The DOI matches its Crossref record; 112 of the 112 references it cites were found in a registry or an index.
Nanotechnology in bone tissue engineering
Open accessAbstract
Nanotechnology represents a major frontier with potential to significantly advance the field of bone tissue engineering. Current limitations in regenerative strategies include impaired cellular proliferation and differentiation, insufficient mechanical strength of scaffolds, and inadequate production of extrinsic factors necessary for efficient osteogenesis. Here we review several major areas of research in nanotechnology with potential implications in bone regeneration: 1) nanoparticle-based methods for delivery of bioactive molecules, growth factors, and genetic material, 2) nanoparticle-mediated cell labeling and targeting, and 3) nano-based scaffold construction and modification to enhance physicochemical interactions, biocompatibility, mechanical stability, and cellular attachment/survival. As these technologies continue to evolve, ultimate translation to the clinical environment may allow for improved therapeutic outcomes in patients with large bone deficits and osteodegenerative diseases.
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Cites
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Cited by
Scaffolds for bone tissue engineering: state of the art and new perspectives
Roseti, L., Parisi, V., Petretta, M., Cavallo, C., Desando, G., Bartolotti, I., & Grigolo, B. (2017) · Materials Science and Engineering: C · doi:10.1016/j.msec.2017.05.017 · Cited by 1,320
Abbasi, R., Shineh, G., Mobaraki, M., Doughty, S., & Tayebi, L. (2023) · Journal of Nanoparticle Research · doi:10.1007/s11051-023-05690-w · Cited by 623
Emerging Applications of Nanotechnology in Healthcare and Medicine
Malik, S., Muhammad, K., & Waheed, Y. (2023) · Molecules · doi:10.3390/molecules28186624 · Cited by 610
Bone tissue engineering via growth factor delivery: from scaffolds to complex matrices
De Witte, T.-M., Fratila-Apachitei, L. E., Zadpoor, A. A., & Peppas, N. A. (2018) · Regenerative Biomaterials · doi:10.1093/rb/rby013 · Cited by 513
Oryan, A., Kamali, A., Moshiri, A., Baharvand, H., & Daemi, H. (2018) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2017.08.184 · Cited by 500
Metadata
- Authors
- Walmsley, G. G., McArdle, A., Tevlin, R., Momeni, A., Atashroo, D., Hu, M. S., Feroze, A. H., Wong, V. W., Lorenz, P. H., Longaker, M. T., & Wan, D. C.
- Venue
- Nanomedicine: Nanotechnology, Biology and Medicine
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 11
- Issue
- 5
- Pages
- 1253-1263
- ISSN
- 1549-9634 (ISSN-L)
- OpenAlex
- W1975968586
- Cited by
- 290
- References
- 112
- FWCI
- 11.17
- Type
- journal article
- Language
- en
- Open access
- green
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- Walmsley, G. G., McArdle, A., Tevlin, R., Momeni, A., Atashroo, D., Hu, M. S., Feroze, A. H., Wong, V. W., Lorenz, P. H., Longaker, M. T., & Wan, D. C. (2015). Nanotechnology in bone tissue engineering. Nanomedicine: Nanotechnology, Biology and Medicine. https://doi.org/10.1016/j.nano.2015.02.013
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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