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Cited by 362

The DOI matches its Crossref record; 174 of the 174 references it cites were found in a registry or an index.

Nanomedicine in the management of microbial infection – Overview and perspectives

Open access
Zhu, Xi, Radovic-Moreno, Aleksandar F., Wu, Jun, Langer, Robert, Shi, Jinjun·2014·Nano Today

Abstract

For more than 2 billion years, microbes have reigned on our planet, evolving or outlasting many obstacles they have encountered. In the 20th century, this trend took a dramatic turn with the introduction of antibiotics and vaccines. Nevertheless, since then, microbes have progressively eroded the effectiveness of previously successful antibiotics by developing resistance, and many infections have eluded conventional vaccine design approaches. Moreover, the emergence of resistant and more virulent strains of bacteria has outpaced the development of new antibiotics over the last few decades. These trends have had major economic and health impacts at all levels of the socioeconomic spectrum – we need breakthrough innovations that could effectively manage microbial infections and deliver solutions that stand the test of time. The application of nanotechnologies to medicine, or nanomedicine, which has already demonstrated its tremendous impact on the pharmaceutical and biotechnology industries, is rapidly becoming a major driving force behind ongoing changes in the antimicrobial field. Here we provide an overview on the current progress of nanomedicine in the management of microbial infection, including diagnosis, antimicrobial therapy, drug delivery, medical devices, and vaccines, as well as perspectives on the opportunities and challenges in antimicrobial nanomedicine.

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Metadata

Authors
Zhu, X., Radovic-Moreno, A. F., Wu, J., Langer, R., & Shi, J.
Venue
Nano Today
Publisher
Elsevier BV
Published
2014-08
Volume
9
Issue
4
Pages
478-498
ISSN
1748-0132 (ISSN-L)
OpenAlex
W2057403423
Cited by
362
References
174
FWCI
10.13
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Nanomedicine in the management of microbial infection – Overview and perspectives. https://app.cochat.ai/papers/10.1016/j.nantod.2014.06.003
The paper
Zhu, X., Radovic-Moreno, A. F., Wu, J., Langer, R., & Shi, J. (2014). Nanomedicine in the management of microbial infection – Overview and perspectives. Nano Today. https://doi.org/10.1016/j.nantod.2014.06.003

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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