The DOI matches its Crossref record; 97 of the 97 references it cites were found in a registry or an index.
Neurophysiology of dystonia: The role of inhibition
Open accessAbstract
The pathophysiology of dystonia has been best studied in patients with focal hand dystonia. A loss of inhibitory function has been demonstrated at spinal, brainstem and cortical levels. Many cortical circuits seem to be involved. One consequence of the loss of inhibition is a failure of surround inhibition, and this appears to directly lead to overflow and unwanted muscle spasms. There are mild sensory abnormalities and deficits in sensorimotor integration; these also might be explained by a loss of inhibition. Increasing inhibition may be therapeutic. A possible hypothesis is that there is a genetic loss of inhibitory interneurons in dystonia and that this deficit is a substrate on which other factors can act to produce dystonia.
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Cites
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Self-citationInteraction between intracortical inhibition and facilitation in human motor cortex.
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Self-citationSpinal motor neuron excitability during the silent period after cortical stimulation
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Cited by
Emerging concepts in the physiological basis of dystonia
Quartarone, A., & Hallett, M. (2013) · Movement Disorders · doi:10.1002/mds.25532 · Cited by 424
Self-citationTranscranial focused ultrasound neuromodulation of the human primary motor cortex
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The non-motor syndrome of primary dystonia: clinical and pathophysiological implications
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Metadata
- Authors
- Hallett, M.
- Venue
- Neurobiology of Disease
- Publisher
- Elsevier BV
- Published
- 2011-05
- Volume
- 42
- Issue
- 2
- Pages
- 177-184
- ISSN
- 0969-9961 (ISSN-L)
- OpenAlex
- W1968263341
- Cited by
- 358
- References
- 97
- FWCI
- 13.02
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.