The DOI matches its Crossref record; 413 of the 413 references it cites were found in a registry or an index.
The energy allocation function of sleep: A unifying theory of sleep, torpor, and continuous wakefulness
Open accessAbstract
The energy allocation (EA) model defines behavioral strategies that optimize the temporal utilization of energy to maximize reproductive success. This model proposes that all species of the animal kingdom share a universal sleep function that shunts waking energy utilization toward sleep-dependent biological investment. For endotherms, REM sleep evolved to enhance energy appropriation for somatic and CNS-related processes by eliminating thermoregulatory defenses and skeletal muscle tone. Alternating REM with NREM sleep conserves energy by decreasing the need for core body temperature defense. Three EA phenotypes are proposed: sleep-wake cycling, torpor, and continuous (or predominant) wakefulness. Each phenotype carries inherent costs and benefits. Sleep-wake cycling downregulates specific biological processes in waking and upregulates them in sleep, thereby decreasing energy demands imposed by wakefulness, reducing cellular infrastructure requirements, and resulting in overall energy conservation. Torpor achieves the greatest energy savings, but critical biological operations are compromised. Continuous wakefulness maximizes niche exploitation, but endures the greatest energy demands. The EA model advances a new construct for understanding sleep-wake organization in ontogenetic and phylogenetic domains.
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“two recent studies in healthy participants revealed an increase, rather than the expected decrease, in SWA following administration of the anti-inflammatory drugs anakinra, an IL-1ra (495), and minocycline (50)”
From The Sleep-Immune Crosstalk in Health and Disease (2019) · cites this paper as [495]
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Items 401–413 of 413
Dongen, H. P. A. V. (2012) · SLEEP · doi:10.5665/sleep.1982 · Cited by 13
Clugston, G. A., & Pj, G. (1982) · PubMed · Cited by 13
Sleep Deprivation in the Rat: XX. Differences in Wake and Sleep Temperatures during Recovery
Feng, P., Shaw, P. J., Bergmann, B. M., Obermeyer, W. H., Tsai, L., Zenko, C. E., & Rechtschaffen, A. (1995) · SLEEP · doi:10.1093/sleep/18.9.797 · Cited by 13
Shaffery, J. P., & Roffwarg, H. P. (2003) · Neuroscience Letters · doi:10.1016/s0304-3940(03)00279-9 · Cited by 12
What is the Meaning of the ATP Surge During Sleep?
Wong‐Riley, M. T. T. (2011) · SLEEP · doi:10.5665/sleep.1102 · Cited by 10
[Polygraphic study of the wakefulness-sleep cycle of a teleostean (Tinca tinca)].
Peyrethon, J., & Dusan-Peyrethon, D. (1967) · PubMed · Cited by 10
Revell, T. K., & Dunbar, S. G. (2007) · Comparative Biochemistry and Physiology Part A Molecular & Integrative Physiology · doi:10.1016/j.cbpa.2007.05.020 · Cited by 8
Sg, L. (1978) · PubMed · Cited by 8
Does the Brain Gain Back Energy During Sleep? But What Does It Mean?
Haddad, G. G. (2011) · SLEEP · doi:10.5665/sleep.1104 · Cited by 7
Sakai, K., & Neuzeret, P. C. (2011) · PubMed · doi:10.4449/aib.v149i4.1380 · Cited by 6
Neural Mechanisms of Sleep-Related Penile Erections
Schmidt, M. H. (2005) · Elsevier eBooks · doi:10.1016/b0-72-160797-7/50032-x · Cited by 6
Self-citationJouvet, M. (1994) · PubMed · Cited by 5
[Study in utero of wakefulness and sleep states in guinea pigs].
Astic, L., & Jouvet-Mounier, D. (1970) · PubMed · Cited by 1
Research works printed but not linked: 2
- Hartmann, 1968, Sleep and dreaming in the elephant, Psychophysiology, 4
- Segura, 1966, Estudios electroencefalograficos en anfibios, Acta Physiologica Latinoamericana, 16, 277
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The Sleep-Immune Crosstalk in Health and Disease
Besedovsky, L., Lange, T., & Haack, M. (2019) · Physiological Reviews · doi:10.1152/physrev.00010.2018 · Cited by 1,479
Crosstalk between metabolism and circadian clocks
Reinke, H., & Asher, G. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-018-0096-9 · Cited by 598
Role of sleep deprivation in immune-related disease risk and outcomes
Garbarino, S., Lanteri, P., Bragazzi, N. L., Magnavita, N., & Scoditti, E. (2021) · Communications Biology · doi:10.1038/s42003-021-02825-4 · Cited by 665
Evidence that birds sleep in mid-flight
Rattenborg, N. C., Voirin, B., Cruz, S. M., Tisdale, R. K., Dell’Omo, G., Lipp, H., Wikelski, M. C., & Vyssotski, A. L. (2016) · Nature Communications · doi:10.1038/ncomms12468 · Cited by 341
McHill, A. W., & Wright, K. P. (2017) · Obesity Reviews · doi:10.1111/obr.12503 · Cited by 330
Metadata
- Authors
- Schmidt, M. H.
- Corresponding author
- Schmidt, Markus H.
- ORCID
- Schmidt, Markus H.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2014-11
- Volume
- 47
- Pages
- 122-153
- ISSN
- 0149-7634 (ISSN-L)
- OpenAlex
- W2009286795
- Cited by
- 291
- References
- 412
- Citations by year
- 2026: 17 · 2025: 26 · 2024: 25 · 2023: 32 · 2022: 18 · 2021: 29 · 2020: 31 · 2019: 29 · 2018: 24 · 2017: 18 · 2016: 26 · 2015: 14 · 2014: 2
- FWCI
- 1.93
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Neuroscience & Biobehavioral Reviews (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Funders
- University of Toronto
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Keywords
- sleep function, REM sleep, NREM sleep, sleep-wake cycle, torpor, energy conservation, endotherms, thermoregulation, skeletal muscle tone, reproductive success, sleep evolution
- MeSH terms
- Animals, Circadian Rhythm, Electroencephalography, Energy Metabolism, Models, Theoretical, Sleep, Sleep Deprivation, Wakefulness, Torpor
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