The DOI matches its Crossref record; 81 of the 81 references it cites were found in a registry or an index.
Thalamic structures and associated cognitive functions: Relations with age and aging
Open accessAbstract
The thalamus, with its cortical, subcortical, and cerebellar connections, is a critical node in networks supporting cognitive functions known to decline in normal aging, including component processes of memory and executive functions of attention and information processing. The macrostructure, microstructure, and neural connectivity of the thalamus changes across the adult lifespan. Structural and functional magnetic resonance imaging (MRI) and diffusion tensor imaging (DTI) have demonstrated, regional thalamic volume shrinkage and microstructural degradation, with anterior regions generally more compromised than posterior regions. The integrity of selective thalamic nuclei and projections decline with advancing age, particularly those in thalamofrontal, thalamoparietal, and thalamolimbic networks. This review presents studies that assess the relations between age and aging and the structure, function, and connectivity of the thalamus and associated neural networks and focuses on their relations with processes of attention, speed of information processing, and working and episodic memory.
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“The modulation of frequencies will take place at coordinate Cz, which receives projections of thalamic structures associated with executive functions of attention and information processing as well as memory processes.20”
From Evaluation of a manualised neurofeedback training in psychosomatic-psychotherapeutic outpatient treatment (Neuro-pp-out): study protocol for a clinical mixed-methods pilot study (2024) · cites this paper as [20]
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Metadata
- Authors
- Fama, R., & Sullivan, E. V.
- Affiliations
- SRI International (US)
- Stanford Medicine (US)
- Corresponding author
- Fama, Rosemary
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 54
- Pages
- 29-37
- ISSN
- 0149-7634 (ISSN-L)
- PMC
- PMC4457546
- OpenAlex
- W2081274529
- Cited by
- 323
- References
- 81
- Citations by year
- 2026: 23 · 2025: 38 · 2024: 56 · 2023: 41 · 2022: 37 · 2021: 28 · 2020: 32 · 2019: 18 · 2018: 18 · 2017: 15 · 2016: 13 · 2015: 4
- FWCI
- 2.65
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neuroscience & Biobehavioral Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Alcohol Abuse and Alcoholism (AA010723, AA017168, AA012388)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced Neuroimaging Techniques and Applications
- Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Keywords
- thalamus, aging, cognitive aging, thalamic connectivity, attention, processing speed, working memory, episodic memory, thalamic nuclei
- MeSH terms
- Adult, Aged, Aged, 80 and over, Aging, Brain, Brain Mapping, Cognition, Female, Humans, Magnetic Resonance Imaging, Male, Memory, Middle Aged, Neural Pathways, Thalamus, Young Adult, Diffusion Tensor Imaging
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