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Association between the CETP polymorphisms and the risk of Alzheimer's disease, carotid atherosclerosis, longevity, and the efficacy of statin therapy

Li, Qing, Huang, Ping, He, Qian-Chao, Lin, Quan-Zhen, Wu, Jian, Yin, Rui-Xing·2014·Neurobiology of Aging
DOI 10.1016/j.neurobiolaging.2013.12.032
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Abstract

The purpose of this meta-analysis was to detect the association between the cholesteryl ester transfer protein gene polymorphisms and the risk of Alzheimer's disease (AD), carotid atherosclerosis, longevity, and the efficacy of statin therapy. Databases of MEDLINE, EMBASE, BIOSIS, the Cochrane Library, and the Chinese National Knowledge Infrastructure were systematically searched. Thirty-two studies were included in this meta-analysis. There was no difference in the I405V, C629A, and Taq1B polymorphisms between AD and control groups. However, stratified analysis showed that AD group had higher B2B2 genotype frequency than control group in Asian populations with APOE4+ in Taq1B. I405V and Taq1B polymorphisms were not associated with the risk of carotid atherosclerosis and longevity. The efficacy of statin therapy was not associated with Taq1B polymorphism. In conclusion, there was no association between cholesteryl ester transfer protein gene polymorphisms and the risk of AD, carotid atherosclerosis, longevity, and the efficacy of statin therapy in the pooled effects of overall population. However, the B2B2 genotype of Taq1B was associated with increased risk of AD in the Asian populations with APOE4+.

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  1. Agerholm-Larsen, 2000, Common cholesteryl ester transfer protein mutations, decreased HDL cholesterol, and possible decreased risk of ischemic heart disease: the Copenhagen City Heart Study, Circulation, 102, 2197, 10.1161/01.CIR.102.18.2197 · DOI
  2. Al-Daghri, 2003, Association between the cholesteryl ester transfer protein TaqI-detectable B polymorphism and low high-density lipoprotein cholesterol concentration in Saudis, Clin. Sci. (Lond), 105, 467, 10.1042/CS20030007 · DOI
  3. Arai, 2003, Deficiency of choresteryl ester transfer protein and gene polymorphisms of lipoprotein lipase and hepatic lipase are not associated with longevity, J. Mol. Med. (Berl), 81, 102, 10.1007/s00109-002-0407-6 · DOI
  4. Arias-Vasquez, 2007, The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease, Neurogenetics, 8, 189, 10.1007/s10048-007-0089-x · DOI
  5. Barter, 2006, Targeting cholesteryl ester transfer protein for the prevention and management of cardiovascular disease, J. Am. Coll. Cardiol., 47, 492, 10.1016/j.jacc.2005.09.042 · DOI
  6. Bauerfeind, 2002, Single nucleotide polymorphism haplotypes in the cholesteryl-ester transfer protein (CETP) gene and lipid phenotypes, Hum. Hered., 54, 166, 10.1159/000070662 · DOI
  7. Bercovich, 2006, The association of common SNPs and haplotypes in the CETP and MDR1 genes with lipids response to fluvastatin in familial hypercholesterolemia, Atherosclerosis, 185, 97, 10.1016/j.atherosclerosis.2005.05.025 · DOI
  8. Brewer, 2004, Increasing HDL cholesterol levels, N. Engl. J. Med., 350, 1491, 10.1056/NEJMp048023 · DOI
  9. Cellini, 2005, Cholesteryl ester transfer protein (CETP) I405V polymorphism and longevity in Italian centenarians, Mech. Ageing Dev., 126, 826, 10.1016/j.mad.2005.01.009 · DOI
  10. Chen, 2008, Cholesteryl ester transfer protein polymorphism D442G associated with a potential decreased risk for Alzheimer's disease as a modifier for APOE epsilon4 in Chinese, Brain Res., 1187, 52, 10.1016/j.brainres.2007.10.054 · DOI
  11. Chen, 2012, Relationship between cholesteryl ester transfer protein(CETP) -TaqIB gene polymorphism and soradic Alzheimer's disease, Zhong Guo Lin Chuang Xin Li Xue Za Zhi, 20, 619
  12. Combarros, 2009, Epistasis in sporadic Alzheimer's disease, Neurobiol. Aging, 30, 1333, 10.1016/j.neurobiolaging.2007.11.027 · DOI
  13. Corbex, 2000, Extensive association analysis between the CETP gene and coronary heart disease phenotypes reveals several putative functional polymorphisms and gene-environment interaction, Genet. Epidemiol., 19, 64, 10.1002/1098-2272(200007)19:1<64::AID-GEPI5>3.0.CO;2-E · DOI
  14. Dachet, 2000, New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol levels: role of Sp1/Sp3 in transcriptional regulation, Arterioscler Thromb. Vasc. Biol., 20, 507, 10.1161/01.ATV.20.2.507 · DOI
  15. Fidani, 2004, An association study of the cholesteryl ester transfer protein TaqI B polymorphism with late onset Alzheimer's disease, Neurosci. Lett., 357, 152, 10.1016/j.neulet.2003.11.071 · DOI
  16. Fiegenbaum, 2005, Pharmacogenetic study of apolipoprotein E, cholesteryl ester transfer protein and hepatic lipase genes and simvastatin therapy in Brazilian subjects, Clin. Chim. Acta, 362, 182, 10.1016/j.cccn.2005.06.005 · DOI
  17. Kakko, 2000, Cholesteryl ester transfer protein gene polymorphisms are associated with carotid atherosclerosis in men, Eur. J. Clin. Invest, 30, 18, 10.1046/j.1365-2362.2000.00595.x · DOI
  18. Kolovou, 2013, Cholesteryl ester transfer protein and ATP-binding cassette transporter A1 genotype alter the atorvastatin and simvastatin efficacy: time for genotype-guided therapy?, Angiology, 64, 266, 10.1177/0003319712444594 · DOI
  19. Kolovou, 2013, The frequency of 4 common gene polymorphisms in nonagenarians, centenarians, and average life span individuals, Angiology
  20. Kolovou, 2010, Cholesteryl ester transfer protein gene polymorphisms and longevity syndrome, Open Cardiovasc. Med. J., 4, 14, 10.2174/1874192401004010014 · DOI
  21. Kuivenhoven, 1998, The role of a common variant of the cholesteryl ester transfer protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group, N. Engl. J. Med., 338, 86, 10.1056/NEJM199801083380203 · DOI
  22. Li, 2008, Association of cholesteryl ester transfer protein TaqIB polymorphism and the effect of simvastatin on lipid profile in patients with coronary atherosclerosis heart disease, Zhong Guo Xun Huan Za Zhi, 23, 98
  23. McKhann, 1984, Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease, Neurology, 34, 939, 10.1212/WNL.34.7.939 · DOI · Paper page
  24. Miltiadous, 2005, Genetic and environmental factors affecting the response to statin therapy in patients with molecularly defined familial hypercholesterolaemia, Pharmacogenet Genomics, 15, 219, 10.1097/01213011-200504000-00005 · DOI
  25. Mohrschladt, 2005, TaqIB polymorphism in CETP gene: the influence on incidence of cardiovascular disease in statin-treated patients with familial hypercholesterolemia, Eur. J. Hum. Genet., 13, 877, 10.1038/sj.ejhg.5201426 · DOI
  26. Murphy, 2012, CETP polymorphisms associate with brain structure, atrophy rate, and Alzheimer's disease risk in an APOE-dependent manner, Brain Imaging Behav., 6, 16, 10.1007/s11682-011-9137-0 · DOI
  27. Novelli, 2008, Lack of replication of genetic associations with human longevity, Biogerontology, 9, 85, 10.1007/s10522-007-9116-4 · DOI
  28. Pan, 2012, Cholesteryl ester transfer protein TaqIB polymorphism and its association with serum lipid levels and longevity in Chinese Bama Zhuang population, Lipids Health Dis., 11, 26, 10.1186/1476-511X-11-26 · DOI
  29. Parra, 2012, The I405V and Taq1B polymorphisms of the CETP gene differentially affect sub-clinical carotid atherosclerosis, Lipids Health Dis., 11, 130, 10.1186/1476-511X-11-130 · DOI
  30. Qureischie, 2008, CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk, Brain Res., 1232, 1, 10.1016/j.brainres.2008.07.047 · DOI · Paper page
  31. Qureischie, 2009, Association of CETP polymorphisms with the risk of vascular dementia and white matter lesions, J. Neural Transm., 116, 467, 10.1007/s00702-008-0180-y · DOI
  32. Rodriguez, 2006, Cholesteryl ester transfer protein (CETP) polymorphism modifies the Alzheimer's disease risk associated with APOE epsilon4 allele, J. Neurol., 253, 181
  33. Shi, 2012, Genetic variants influencing human aging from late-onset Alzheimer's disease (LOAD) genome-wide association studies (GWAS), Neurobiol. Aging, 33, 1849, 10.1016/j.neurobiolaging.2012.02.014 · DOI
  34. Shi, 2012, Relationship between CEPT gene single neucleotide polymorphisms and Alzheimer's disease in northeast China population, Zhong Guo Dang Dai Yi Yao, 19, 5
  35. Soyal, 2011, Cholesteryl ester transfer protein and hepatic lipase gene polymorphisms: effects on hepatic mRNA levels, plasma lipids and carotid atherosclerosis, Atherosclerosis, 216, 374, 10.1016/j.atherosclerosis.2011.01.052 · DOI
  36. Sun, 2007, Correlation of the polymorphisms of CETP gene with the natural longevity in Uygur population, Yi Xue Yan Jiu Za Zhi, 36, 27
  37. Winkelmann, 2003, Haplotypes of the cholesteryl ester transfer protein gene predict lipid-modifying response to statin therapy, Pharmacogenomics J., 3, 284, 10.1038/sj.tpj.6500195 · DOI
  38. Xiao, 2012, Association studies of several cholesterol-related genes (ABCA1, CETP and LIPC) with serum lipids and risk of Alzheimer's disease, Lipids Health Dis., 11, 163, 10.1186/1476-511X-11-163 · DOI
  39. Yin, 2012, Several genetic polymorphisms interact with overweight/obesity to influence serum lipid levels, Cardiovasc. Diabetol., 11, 123, 10.1186/1475-2840-11-123 · DOI
  40. Yu, 2012, The CETP I405V polymorphism is associated with an increased risk of Alzheimer's disease, Aging Cell., 11, 228, 10.1111/j.1474-9726.2011.00777.x · DOI
  41. Zhang, 2008, TaqIB poIymorphism in CETP gene in 140 hyperlipemia patients and lipid regulating effects of statins, Guang Dong Yi Xue Yuan Xue Bao, 26, 492
  42. Zhang, 2011, Cholesteryl ester transfer protein I405V polymorphism and its association with longevity in Hainan centenarians, Zhong Guo Lao Nian Xue Za Zhi, 31, 3011
  43. Zhu, 2005, Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease, Neurosci. Lett., 381, 36, 10.1016/j.neulet.2005.01.078 · DOI

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Metadata

Authors
Li, Q., Huang, P., He, Q.-C., Lin, Q.-Z., Wu, J., & Yin, R.-X.
Venue
Neurobiology of Aging
Publisher
Elsevier BV
Published
2014-06
Volume
35
Issue
6
Pages
1513.e13-1513.e23
ISSN
0197-4580
DOI
10.1016/j.neurobiolaging.2013.12.032
Cited by
16
References
1
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Funders
National Natural Science Foundation of China (81200205, 30960130)

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