XNAT Central: Open sourcing imaging research data
Open accessAbstract
XNAT Central is a publicly accessible medical imaging data repository based on the XNAT open-source imaging informatics platform. It hosts a wide variety of research imaging data sets. The primary motivation for creating XNAT Central was to provide a central repository to host and provide access to a wide variety of neuroimaging data. In this capacity, XNAT Central hosts a number of data sets from research labs and investigative efforts from around the world, including the OASIS Brains imaging studies, the NUSDAST study of schizophrenia, and more. Over time, XNAT Central has expanded to include imaging data from many different fields of research, including oncology, orthopedics, cardiology, and animal studies, but continues to emphasize neuroimaging data. Through the use of XNAT’S DICOM metadata extraction capabilities, XNAT Central provides a searchable repository of imaging data that can be referenced by groups, labs, or individuals working in many different areas of research. The future development of XNAT Central will be geared towards greater ease of use as a reference library of heterogeneous neuroimaging data and associated synthetic data. It will also become a tool for making data available supporting published research and academic articles.
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The OASIS-3 data are hosted on XNAT Central.
“The OASIS-3 data are hosted on XNAT Central 56 (https://central.xnat.org), a publicly accessible data-repository.”
From OASIS-3: Longitudinal Neuroimaging, Clinical, and Cognitive Dataset for Normal Aging and Alzheimer Disease (2019) · cites this paper as [56]
The Hosted Data section (page unavailable) says XNAT Central hosts the OASIS Brains imaging studies, and the Introduction identifies it as a publicly accessible repository. The paper describes cross-sectional and longitudinal OASIS studies but does not identify the hosted data as OASIS-3. (LLM, conf=0.86)
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Cites
Marcus, D. S., Wang, T. H., Parker, J., Csernansky, J. G., Morris, J. C., & Buckner, R. L. (2007) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2007.19.9.1498 · Cited by 2,163 · see citing works
Self-citationMarcus, D. S., Fotenos, A. F., Csernansky, J. G., Morris, J. C., & Buckner, R. L. (2009) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.2009.21407 · Cited by 635 · see citing works
Self-citationMapping distributed brain function and networks with diffuse optical tomography
Eggebrecht, A. T., Ferradal, S. L., Robichaux‐Viehoever, A., Hassanpour, M. S., Dehghani, H., Snyder, A. Z., Hershey, T. G., & Culver, J. P. (2014) · Nature Photonics · doi:10.1038/nphoton.2014.107 · Cited by 602 · see citing works
The extensible neuroimaging archive toolkit
Marcus, D. S., Olsen, T. R., Ramaratnam, M., & Buckner, R. L. (2007) · Neuroinformatics · doi:10.1385/ni:5:1:11 · Cited by 460 · see citing works
Self-citationToward open sharing of task-based fMRI data: the OpenfMRI project
Poldrack, R. A., Barch, D. M., Mitchell, J. P., Wager, T. D., Wagner, A. D., Devlin, J. T., Cumba, C., Koyejo, S., & Milham, M. P. (2013) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2013.00012 · Cited by 341 · see citing works
Data sharing in neuroimaging research
Poline, J., Breeze, J. L., Ghosh, S., Gorgolewski, K. J., Halchenko, Y. O., Hanke, M., Haselgrove, C., Helmer, K. G., Keator, D. B., Marcus, D. S., et al. (2012) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2012.00009 · Cited by 262 · see citing works
Self-citationGrandjean, J., Schroeter, A., He, P., Tanadini, M., Keist, R., Krstic, D., Konietzko, U., Klohs, J., Nitsch, R. M., & Rudin, M. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.4762-13.2014 · Cited by 70 · cited 2× · see citing works
“…provides clinical, cognitive, genetic, and imaging data for 450 subjects, includingmanywith diagnosed schizophrenia (Wang et al., 2013); and animal studies on cerebral amyloidosis (Grandjean et al., 2014) and functional networksmeasuredwith diffuse optical tomography (Eggebrecht et al., 2014).”
BackgroundNorthwestern University Schizophrenia Data and Software Tool (NUSDAST)
Wang, L., Kogan, A., Cobia, D. J., et al. (2013) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2013.00025 · Cited by 45 · see citing works
Schwartz, Y., Barbot, A., Thyreau, B., Frouin, V., Varoquaux, G. P., Aditya, S., Marcus, D. S., & Poline, J. (2012) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2012.00012 · Cited by 39 · see citing works
Self-citationDicomBrowser: Software for Viewing and Modifying DICOM Metadata
Archie, K. A., & Marcus, D. S. (2012) · Journal of Imaging Informatics in Medicine · doi:10.1007/s10278-012-9462-x · Cited by 22 · see citing works
Self-citationData dictionary services in XNAT and the Human Connectome Project
Herrick, R., McKay, M., Olsen, T., et al. (2014) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2014.00065 · Cited by 13 · see citing works
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LaMontagne, P. J., Benzinger, T. L., Morris, J. C., Keefe, S., Hornbeck, R., Xiong, C., Grant, E., Hassenstab, J., Moulder, K., Vlassenko, A. G., et al. (2019) · medRxiv · doi:10.1101/2019.12.13.19014902 · Cited by 779 · see citing works
Self-citationEverything Matters: The ReproNim Perspective on Reproducible Neuroimaging
Kennedy, D. N., Abraham, S. A., Bates, J. F., Crowley, A., Ghosh, S., Gillespie, T., Goncalves, M., Grethe, J. S., Halchenko, Y. O., Hanke, M., et al. (2019) · Frontiers in Neuroinformatics · doi:10.3389/fninf.2019.00001 · Cited by 113 · see citing works
- Authors
- Herrick, R., Horton, W., Olsen, T., McKay, M., Archie, K. A., & Marcus, D. S.
- Affiliations
- Washington University in St. Louis (US)
- Corresponding author
- Herrick, Rick
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2016-01
- Volume
- 124
- Issue
- Pt B
- Pages
- 1093-1096
- ISSN
- 1053-8119 (ISSN-L)
- PMC
- PMC4965359
- OpenAlex
- W787452952
- Semantic Scholar
- 902e130f11b8c0c2d46e0296427914e02beec632
- Cited by
- 62
- References
- 11
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 7 · 2023: 13 · 2022: 8 · 2021: 10 · 2020: 6 · 2019: 3 · 2018: 5 · 2017: 1 · 2016: 1 · 2015: 1
- FWCI
- 7.17
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- NeuroImage (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (5 R01 EB009352, U24 RR026057, U54 EB005149, U24 RR025736)
- Topics
- Physical Sciences › Computer Science › Information Systems › Research Data Management Practices
- Social Sciences › Sociology and Political Science › Data Analysis and Archiving
- Social Sciences › Decision Sciences › Information Systems and Management › Scientific Computing and Data Management
- Keywords
- neuroimaging data, open research data, XNAT, DICOM metadata, data sharing, OASIS, schizophrenia, synthetic data, imaging informatics
- MeSH terms
- Brain, Humans, Information Systems, Medical Informatics, Schizophrenia, Databases, Factual, Access to Information, Information Dissemination, Neuroimaging
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