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Amyotrophic Lateral Sclerosis-Associated SOD1 Mutant Proteins Bind and Aggregate with Bcl-2 in Spinal Cord Mitochondria

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Pasinelli, Piera, Belford, Mary Elizabeth, Lennon, Niall, Bacskai, Brian J, Hyman, Bradley T, Trotti, Davide, Brown, Robert H·2004·Neuron

DOI 10.1016/j.neuron.2004.06.021

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“Today, while there are several theories of aging, the basic principle of most of them is still oxidative stress (Finkel and Holbrook, 2000; Payne and Chinnery, 2015).”
Background
State of play in amyotrophic lateral sclerosis genetics
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See all 506

Authors: Pasinelli, P., Belford, M. E., Lennon, N., Bacskai, B. J., Hyman, B. T., Trotti, D., & Brown, R. H.
Venue: Neuron
Publisher: Elsevier BV
Published: 2004-07
Volume: 43
Issue: 1
Pages: 19-30
ISSN: 0896-6273 (ISSN-L)
DOI: 10.1016/j.neuron.2004.06.021
OpenAlex: W2015266340
Cited by: 506
References: 44
FWCI: 27.42
Type: journal article
Language: en
Open access: bronze

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Amyotrophic Lateral Sclerosis-Associated SOD1 Mutant Proteins Bind and Aggregate with Bcl-2 in Spinal Cord Mitochondria

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