The Many Faces of Tau
Cited by (900)
Items 701–800 of 900
- Rational Modulation of Liquid–Liquid Phase Separation Offers Novel Ways to Combat TauopathiesXingxing Zhang, Lihua Wang, Nixin Lin, Meng Ying Gao, Yongqi Huang · 2025 · International Journal of Molecular Sciences
- Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophyNimrod Miller, Zhaofa Xu, Katharina A. Quinlan, Amy Ji, Jered V. McGivern, Zhihua Feng, Han Shi, Chien‐Ping Ko, Li‐Huei Tsai, Charles J. Heckman et al. · 2023 · Proceedings of the National Academy of Sciences
- Trichloroacetic acid treatment as a tricky way for rapid purification of 1N/4R tau proteinKazem Asadollahi, Saharnaz Rafiee, Gholam Hossein Riazi, Shahriar Pooyan, Ali Afrasiabi · 2015 · Protein Expression and Purification
- Reward motivation and cognitive flexibility in tau null-mutation miceSara Oberrauch, Jeremy A. Metha, Maddison L. Brian, Samuel A. Barnes, Travis J. Featherby, Andrew John Lawrence, Daniël Hoyer, Carsten Murawski, Laura H. Jacobson · 2020 · Neurobiology of Aging
- Molecular Mechanism of Tau Misfolding and Aggregation: Insights from Molecular Dynamics SimulationHaiyang Zhong, Hongli Liu, Huanxiang Liu · 2023 · Current Medicinal Chemistry
- Suspended microtubules demonstrate high sensitivity and low experimental variability in kinesin bead assayMehmet Cagatay Tarhan, Yslam Orazov, Ryuji Yokokawa, Stanislav L. Karsten, Hiroyuki Fujita · 2013 · The Analyst
- HACS1 signaling adaptor protein recognizes a motif in the paired immunoglobulin receptor B cytoplasmic domainJamie J. Kwan, Sladjana Slavkovic, Michael J Piazza, Dingyan Wang, Thorsten Dieckmann, Philip E. Johnson, Xiao‐Yan Wen, Logan W. Donaldson · 2020 · Communications Biology
- Prediction and verification of the AD-FTLD common pathomechanism based on dynamic molecular network analysisMeihua Jin, Xiaocen Jin, Hidenori Homma, Kyota Fujita, Hikari Tanaka, Shigeo Murayama, Hiroyasu Akatsu, Kazuhiko Tagawa, Hitoshi Okazawa · 2021 · Communications Biology
- Structural adjustment and social protection in the Middle East and North Africa: food subsidies in JordanYusuke Kawamura · 2014 · Contemporary Arab Affairs
- Tau Protein and β-Amyloid Associated with Neurodegeneration in Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis (EAE), a Mouse Model of Multiple SclerosisGrażyna Pyka‐Fościak, Ewa Jasek-Gajda, B. Wójcik, GRZEGORZ J. LIS, Jan A. Litwin · 2024 · Biomedicines
- Unraveling APOE4's Role in Alzheimer's Disease: Pathologies and Therapeutic StrategiesSiddhant Tripathi, Yashika Sharma, Dileep Kumar · 2024 · Current Protein and Peptide Science
- Big Tau: Structure, Evolutionary Divergence, and Emerging Roles in Cytoskeletal Dynamics and TauopathiesItzhak Fischer, Peter W. Baas · 2026 · Cells
- Salt Dependence Conformational Stability of the Dimeric SAM Domain of MAPKKK Ste11 from Budding Yeast: A Native-State H/D Exchange NMR StudyAnirban Bhunia, Humaira Ilyas, Surajit Bhattacharjya · 2020 · Biochemistry
- Protective Effect of Hydroxysafflor Yellow A against Chronic Mild Stress-induced Memory Impairments by Suppressing Tau Phosphorylation in MiceYing Wang, Qiang Wang, Jun Chen, Lihe Yao, Ni Tang, Zhenxiu Jiang, Yu Luo · 2021 · Current Medical Science
- Biomedical research brings mTBI biomarkers a step closer to the bedside – implementation in clinical practiceMartina Martiníková, Róbert Ružiňák, Egon Kurča, Michael T. Grey, Štefan Sivák · 2023 · General Physiology and Biophysics
- Mixtures of Intrinsically Disordered Neuronal Protein Tau and Anionic Liposomes Reveal Distinct Anionic Liposome-Tau Complexes Coexisting with Tau Liquid–Liquid Phase-Separated CoacervatesChristine K. Tchounwou, Anjali J. Jobanputra, Dylan Lasher, Bretton J. Fletcher, Jorge Jacinto, Arjun Bhaduri, Rebecca L. Best, William S. Fisher, Kai K. Ewert, Youli Li et al. · 2024 · Langmuir
- Electrophysiology-based screening identifies neuronal HtrA serine peptidase 2 (HTRA2) as a synaptic plasticity regulator participating in tauopathyNaizhen Zheng, Kun Li, Jing Cao, Zijie Wang, Liang Zhang, Zihao Zhao, Jiawei He, Yong Wang, Xiang Zhu, Yiqing Chen et al. · 2025 · Translational Psychiatry
- Role of Tau Protein Hyperphosphorylation in Diabetic Retinal NeurodegenerationJingyu Mu, Zengrui Zhang, Chao Jiang, Haoming Geng, Junguo Duan · 2025 · Journal of Ophthalmology
- Conformation- and phosphorylation-dependent electron tunnelling across self-assembled monolayers of tau peptidesAli Akbar Ashkarran, A. Hosseini, R. Loloee, George L. Perry, Ki‐Bum Lee, Mikael Lund, Mohammad Reza Ejtehadi, Morteza Mahmoudi · 2021 · Journal of Colloid and Interface Science
- TauopathyHao Chi, Tzu‐Kang Sang, Hui-Yun Chang · 2019 · IntechOpen eBooks
- Tau Isoforms Imbalance Impairs the Axonal Transport of the Amyloid Precursor Protein in Human NeuronsValentina Lacovich, Sonia L. Espíndola, Matías Alloatti, Victorio M. Pozo Devoto, Lucas Eneas Cromberg, Mária E. Čarná, Giancarlo Forte, Jean‐Marc Gallo, Luciana Bruno, Gorazd Bernard Stokin et al. · 2017 · Journal of Neuroscience
- Prospects and Challenges for Alzheimer TherapeuticsMichael S. Wolfe · 2016 · Elsevier eBooks
- Grove Arctic Curves from Periodic Cluster Modular TransformationsTerrence George · 2019 · International Mathematics Research Notices
- Serum tau concentration after diving – an observational pilot studyAnders Rosén, Nicklas Oscarsson, Andreas Kvarnström, Mikael Gennser, Göran Sandström, Kaj Blennow, Helen Seeman-Lodding, Henrik Zetterberg · 2019 · Diving and Hyperbaric Medicine Journal
- Potential Therapeutic Strategies to Prevent the Progression of Alzheimer to Disease StatesEster Aso, Isidró Ferrer · 2013 · InTech eBooks
- Potential neuroprotective strategies against tauopathyJeanna M. Wheeler, Chris R. Guthrie, Brian C. Kraemer · 2012 · Biochemical Society Transactions
- Phonetic variation in Standard Scottish English: Rhotics in DundeeThomas Jauriberry, Rudolph Sock, Albert Hamm · 2015
- Molecular Interactions between Tau Protein and TIA1: Distinguishing Physiological Condensates from Pathological FibrilsSafwa T. Kizhakkeduth, Arshad Abdul Vahid, Muhammed Shafeek Oliyantakath Hassan, Anagha K. Parambil, Parul Jain, Vinesh Vijayan · 2024 · ACS Chemical Neuroscience
- Salivary total tau: a clinically practical measure of tau neuropathology in Alzheimer’s diseaseAlison R. Bamford, Christopher Logan, Q B Do, Kelly Nguyen, Liv C. McMillan, Michael A. Yassa, William Rodman Shankle, Elizabeth A. Thomas · 2026 · Journal of Neurology
- Harmine and its derivatives: A promising multi-target therapeutic avenue for Alzheimer’s diseaseXue Shen, Xiaoyu Dong, Jianfei Nao · 2026 · Neuroscience
- Tridimensional Structural Analysis of Tau Isoforms Generated by Intronic RetentionIndalo Domene-Serrano, Raquel Cuadros, Félix Hernández, Jesús Ávila, Ismael Santa‐María · 2023 · Journal of Alzheimer s Disease Reports
- Recent Advances in Mapping Protein Self-Assembly and Aggregation for Common ProteinopathiesShapla Bhattacharya, Damien Thompson · 2024 · Acta Physica Polonica A
- Mechanistic insights into the molecular and cellular basis of Alzheimer's diseaseA Issa · 2024 · Elsevier eBooks
- Advancements in diagnosing Post-concussion Syndrome: insights into epidemiology, pathophysiology, neuropathology, neuroimaging, and salivary biomarkersIoannis Asterios Mavroudis, Foivos Petridis, Alin Stelian Ciobica, Fatima Zahra Kamal, Manuela Pădurariu, Dimitrios A. Kazis · 2025 · Acta Neurologica Belgica
- Shapeshifter W-Tau Peptide Inhibits Tau Aggregation and Disintegrates Paired Helical FilamentsIndalo Domene-Serrano, Raquel Cuadros, Vega García‐Escudero, Francisco Vallejo-Bedia, Ismael Santa‐María, Laura Vallés‐Saiz, Félix Hernández, Jesús Ávila · 2025 · Biochemistry
- Effects of interval exercise and diurnal variation on blood biomarkers for sport-related concussion: A crossover cohort studyLinden C. Penner, Jason Tabor, Joel S. Burma, Heather C Godfrey, Jean-Michel F Galarneau, Jennifer Gradi Cooper, Mohammad Ghodsi, Cheryl Lea Wellington, Chantel Teresa Debert, Carolyn A. Emery et al. · 2025 · Journal of science and medicine in sport
- Nutrient sensing receptor GPRC6A regulates mTORC1 signaling and Tau biologyChao Ma, Kelsey Campbell, Andrii Kovalenko, Junyan Li, Leslie A. Sandusky‐Beltran, Huimin Liang, Jerry B. Hunt, John Ivan T. Calahatian, Mani Kallupurackal, Shalini Pandey et al. · 2025 · Neurobiology of Disease
- Pericytes and the Neurovascular Unit: The Critical Nexus of Alzheimer Disease Pathogenesis?Steven P. Cercy · 2021 · Exploratory Research and Hypothesis in Medicine
- Blood Markers in Relation to a History of Traumatic Brain Injury Across Stages of Cognitive Impairment in a Diverse CohortChristian LoBue, Barbara Elena Stopschinski, Nil Saez-Calveras, Peter M. Douglas, Ryan M. Huebinger, C. Munro Cullum, John Hart, Mitzi M. Gonzales · 2023 · Journal of Alzheimer s Disease
- Neuroregeneration: Disease Modeling and Therapeutic Strategies for Alzheimer’s and Parkinson’s DiseasesAngel J. Santiago-Lopez, Candice M. Hovell, Hyunjung Lee, YongTae Kim · 2015 · Biosystems & biorobotics
- Cytoskeletal Elements in Neurotoxicity*Sally J. Pyle, Kenneth R. Reuhl · 2010 · Elsevier eBooks
- Glymphatic SystemHelene Benveniste, Maiken Nedergaard · 2015 · Springer eBooks
- The Therapeutic Effects of Seven Lycopodium Compounds on Cell Models of Alzheimer’s DiseaseQian Guo, Qinfeng Cai, Fang Huang, Zhen Cheng Wei, Jian‐Zhi Wang, Bin Zhang, Rong Liu, Yang Yang, Xiaochuan Wang, Honglian Li · 2022 · Journal of Alzheimer s Disease
- Tau protein aggregation: A therapeutic target for neurodegenerative diseasesAryan Duggal, Drishti Mahindru, Kirti Baghel, Sanjana Mehrotra, Vijay Kumar Prajapati · 2025 · Advances in protein chemistry and structural biology
- Drosophila wing is a high-throughput and versatile screening tool for Tau-mediated disease mechanisms and drug discoveryMiguel Ramírez Moreno, Amber S. Cooper, Tianshun Lian, Jie Liu, Seyedehleila Abtahi, Efthimios M. C. Skoulakis, Lovesha Sivanantharajah, Douglas W. Allan, Amritpal K. Mudher · 2026 · Disease Models & Mechanisms
- Mechanistic insights into the synaptic damage-repair and regeneration processes in neurodegenerative Alzheimer’s disease: phytochemicals as neuroprotective agentsBharti Yadav, Prabhakar Gangwar, Kirti Kumari, Anuradha Yadav, Rashmi Rao, Keshav Kumar, Harkomal Verma, Monisha Dhiman, Anil Kumar Mantha · 2026 · Frontiers in Synaptic Neuroscience
- Candidate biomarkers and CSF profiles for alzheimer’s disease and CADASILAbdalla Bowirrat, Bishara Bisharat, Nseir William, Omary Muhamad, Mustafa Yassin · 2015 · Journal of Alzheimer’s Disease & Parkinsonism
- Neurochemical Aspects of Alzheimer DiseaseA. A. Farooqui · 2016 · Springer eBooks
- Endocrine Receptors: The Potential Therapeutic Targets for Alzheimer’sTabassum Zafar, Ab Qayoom Naik, Bashirulla Shaik · 2023 · Springer eBooks
- Stem Cells Vs Exosomes: Promising Therapeutic Approach and Biomarkers Agent against Neurodegenerative DisordersJohra Khan, I. İrem Tatlı · 2023 · Springer eBooks
- Development of a sensor to detect methylmercury toxicityAkio Sumioka, Fusako Usuki, Masatake Fujimura · 2024 · Scientific Reports
- Effect of stress on neuronal cell: Morphological to molecular approachIshita Bhardwaj, Sippy Singh, Atifa Haseeb Ansari, Swayam Prabha Rai, Durgesh Singh · 2025 · Progress in brain research
- Biomarkers for Alzheimer’s Disease: Imagination or Reality-View and Review!Mustafa Yassin, Zaher Armaly, Bishara Bisharat, Abdalla Bowirrat · 2013 · Journal of Behavioral and Brain Science
- Chemical Modulators of Protein Misfolding, Neurodegeneration and TauPierfausto Seneci · 2015 · Elsevier eBooks
- Date seeds alleviate behavioural and neuronal complications of metabolic syndrome in ratsYosra Dallagi, Dalila Rahali, Morgane Perrotte, Houssem Dkhili, Asma Korsan, Michèle Véronique El May, Saloua El Fazâa, Charles Ramassamy, Nargès El Golli · 2020 · Archives of Physiology and Biochemistry
- Preclinical models of Alzheimer’s disease for identification and preclinical validation of therapeutic targets: from fine-tuning strategies for validated targets to new venues for therapyBruno Vasconcelos, Matthew Bird, Ilie‐Cosmin Stancu, Dick Terwel, Ilse Dewachter · 2017 · Elsevier eBooks
- The role of protein phosphatase 2A tau axis in traumatic brain injury therapyMaibouge Tanko Mahamane Salissou, Yacoubou Abdoul Razak Mahaman, Xiaochuan Wang, Rabiu Abdussalam Magaji · 2022 · Beni-Suef University Journal of Basic and Applied Sciences
- Deliberate self-harm in the South West: Setting a research agendaYvette Morey, Lynne C. Eagle, Julia Verne, Helen Cook · 2011 · ResearchOnline at James Cook University (James Cook University)
- Multiple amyloid binding sites in Alzheimer brain and their interaction with synaptic and inflammatory mechanismsRuiqing Ni · 2015 · Figshare
- Designed Peptides that Control Protein NanoassembliesHiroshi Inaba, Kazunori Matsuura · 2023 · Supramolecular Nanotechnology
- Tau-Centric Therapies for Treating Alzheimer’s DiseaseShmma Quraishe, C.M. Cowan, Amritpal K. Mudher · 2017 · Elsevier eBooks
- Quantification of Methylation and Phosphorylation StoichiometryChristopher A. Ayoub, Khadijah I. Moore, Jeff Kuret · 2024 · Methods in molecular biology
- Prion protein prevents the inhibition of large-conductance calcium-activated potassium channel by Tau peptide K18 oligomersYevheniia Kravenska, Piotr Koprowski, Hanna Nieznańska, Krzysztof Nieznański · 2024 · Biochemical and Biophysical Research Communications
- Effect of PHF-1 hyperphosphorylation on the seeding activity of C-terminal Tau fragmentsLéa El Hajjar, Emmanuelle Boll, François‐Xavier Cantrelle, Clarisse Bridot, Isabelle Landrieu, Caroline Smet‐Nocca · 2025 · Scientific Reports
- Isoforms of Phosphorylated Tau as Potential Biomarkers for Alzheimer’s Disease: The Contribution of Mass Spectrometry-Based ProteomicsMarco Agostini, Pietro Traldi, Mahmoud H. Hamdan · 2025 · NeuroSci
- Brain Injury Biomarkers in Humans Undergoing General Anaesthesia and Noncerebral SurgeryRichard Vithal, Ali El‐Merhi, Amar Chandan, Anna Kosovic, Helena Odenstedt Hergès, Henrik Zetterberg, Christina Biörserud, Miroslaw Staron, Jaquette Liljencrantz, Linda Block · 2025 · Acta Neurologica Scandinavica
- The application of directly induced neurons into neurodegenerative disease modelingKeita Matsumoto, Sumihiro Maeda · 2025 · Neuroscience Research
- Integrated network pharmacology, molecular docking and MD simulation unravel neuroprotective phytochemicals from aframomum melegueta targeting microglial neuroinflammation in Alzheimer’s diseaseSameera Khan, Prinsa, Nargis Bano, Faaizah Fazal, Shakir Ahamad, Supriyo Saha, Nawab John Dar, Shahnawaz Ali Bhat · 2026 · Network Modeling Analysis in Health Informatics and Bioinformatics
- Canine Cognitive Dysfunction and Alzheimer’s Disease: Pathophysiological Relationships and the Impact of Glymphatic System Impairment on NeurodegenerationMaurizio Dondi, Ezio Bianchi, Paolo Borghetti, Rosanna Di Lecce, Giacomo Gnudi, Chiara Guarnieri, Valentina Buffagni, Francesca Ravanetti, Roberta Saleri, Attilio Corradi · 2026 · Veterinary Sciences
- Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's diseaseJoshua T. Skrehot, Dmitry Kurouski · 2026 · Protein Science
- Spatial-temporal reasoning applications of computational intelligence in the game of Go and computer networksTae Hyung Kim · 2012
- Cellular Prion Protein and CancersWei Xin, Man‐Sun Sy, Chaoyang Li · 2012 · Springer eBooks
- A stochastic approach to rhotic variation in Spanish codasMark Gibson · 2015 · Loquens
- Tau Phosphorylation as a Therapeutic Target in Alzheimer’s DiseaseMiguel Medina, Jesús Ávila · 2016 · Elsevier eBooks
- Sensitive immunoassay testing platformsMaximo J Marin, Xander M.R. van Wijk · 2020 · Elsevier eBooks
- Protein–Protein Interactions in Neurodegenerative DiseasesKrishna Mohan Poluri, Khushboo Gulati, Deepak Kumar Tripathi, Nupur Nagar · 2023 · Springer eBooks
- Perspective Chapter: Challenges in the Diagnosis of Post-Concussion Syndrome – Epidemiology, Pathophysiology, Neuropathology, Neuroimaging Biomarkers, and Salivary BiomarkersIoannis Asterios Mavroudis, Foivos Petridis, Alin Stelian Ciobica, Fatima Zahra Kamal, Manuela Pădurariu · 2024 · IntechOpen eBooks
- Autophagy in Alzheimer’s disease: A Cleaning Service Out-of-order?Sónia C. Correia, Paula Isabel Moreira, George L. Perry · 2015 · Current topics in neurotoxicity
- Copper and Alzheimer Disease: The Good, the Bad and the UglyYa Hui Hung, Ashley Ian Bush, Robert A. Cherny · 2012 · Springer eBooks
- Reduce the Risk of Dementia; Early Diagnosis of Alzheimer’s DiseaseShweta Jakhmola, Hem Chandra Jha · 2018 · Advances in intelligent systems and computing
- Antisense-Oligonukleotide IClaudia D. Wurster, Albert Christian Ludolph, Denise Lehmann, Heiko Graf · 2018 · Nervenheilkunde
- Влияние бета-амилоидных пептидов и основного стресс-белка HSP70 на протеом клеток SH-SY5Y нейробластомы человекаAlexander P. Rezvykh, М. М. Юринская, М. Г. Винокуров, George Sergeevich Krasnov, Vladimir A. Mitkevich, Alexander А. Makarov, Michael B. Evgen’ev, Olga G. Zatsepina · 2018 · Molecular Biology
- Tau, Tangles and Tauopathies: Insights from Drosophila Disease ModelsNisha Nisha, Pragati, Shweta Tandon, Aqsa Aqsa, Prerna Aggarwal, Surajit Sarkar · 2019 · Springer eBooks
- Soluble 4R0N Tau Abrogates Endocytic Vesicular DynamicsTharun Selvam Mahendran, Shwetha Suresh, Lakshmi Garimella, Ravi R. Manjithaya · 2020 · Frontiers in Aging Neuroscience
- Glymphatic SystemHelene Benveniste, Maiken Nedergaard · 2022 · Springer eBooks
- The aging synapse: Synaptic proteome changes in mouse models of agingMarlene J. Végh · 2012 · Digital Academic REpository of VU University Amsterdam (Vrije Universiteit Amsterdam)
- Drug therapies for Alzheimer's diseaseEmma Louise Cunningham, Anthony Peter Passmore · 2013 · British Journal of Mental Health Nursing
- Traumatic Brain Injury and Neurodegenerative DiseaseDawn McGuire · 2018 · Wiley eBooks
- Overexpression of HIF-2α in Protected Regions of Alzheimer’s disease Resilient CasesVivianne Mitri · 2020 · medRxiv
- Iron Homeostasis and NeurodegenerationRobert R. Crichton · 2016 · Wiley eBooks
- Tau-seed interactome analysis reveals distinct functional signatures in Alzheimer’s disease across model systemsPablo Martínez, Henika Patel, Yanwen You, Daniella Lopes, Armando Amaro, Nur Jury, Yuhao Min, Javier Redding‐Ochoa, Sayan Dutta, Jean‐Christophe Rochet et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Tau Ablation Rewires Brain Cell Programs in Health and Restores Function in DiseaseChimal-Juárez, Enrique, Patel, Henika, Jury-Garfe, Nur, Dabin, Luke C., Vidal, Ruben, Kim, Jungsu, Lasagna-Reeves, Cristian A. · 2026 · bioRxiv
- Pharmacodynamic Mechanisms of Tolfenamic Acid Induced SP1 Degradation Relative to Alzheimer's Disease PathologyLina I. Adwan · 2013 · Digital Commons - URI (University of Rhode Island)
- Interaction between Peptide Pheromone or Its Truncated Derivatives and Pheromone Receptor of the Fission Yeast Schizosaccharomyces pombe Examined by a Force Spectroscopy Study and a GFP Reporter AssaySho Hidaka, Osamu Nikaido, Shoichi Kiyosaki, Atsushi Ikai, Toshiya Osada · 2013 · Journal of Surface Engineered Materials and Advanced Technology
- Las percepciones de amenazas y de seguridad entre Europa y el mundo árabeMartín Jerch, Alejandro V. Lorca Corróns · 2011 · Estudios Internacionales
- depression in the hippocampus Microtubule-associated protein tau is essential for long-termEunjoon Kim, Graham L. Collingridge, Akihiko Takashima, Kwangwook Cho Christopher Brown, Tsutomu Hashikawa, Miyuki Murayama, Heon Seok, Ioannis Sotiropoulos, Tetsuya Kimura, Daniel J. Whitcomb et al. · 2013
- Tau Pathology: A Selected View on the Current StatusIllana Gozes · 2012 · Advances in predictive, preventive and personalised medicine
- CD64-mediated specific elimination of M1-polarized macrophages : implications for therapeutic intervention in chronic inflammatory diseasesDmitrij Hristodorov, Universitätsprofessor Dr. Rainer Fischer · 2013 · RWTH Publications (RWTH Aachen)
- The Tau of Myelin Basic Protein (MBP): Biophysical Studies of Microtubule Assembly by MBPAgata Zienowicz · 2014 · The Atrium (University of Guelph)
- Dysregulation of neuronal calcium signaling impairs axonal transport independent of tau in a model of Alzheimer's diseaseKathlyn J. Gan · 2014 · Summit (Simon Fraser University)