ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

Kanekiyo, Takahisa, Xu, Huaxi, Bu, Guojun·2014·Neuron

DOI 10.1016/j.neuron.2014.01.045

Cited by (626)

Items 501–600 of 626

A Toxicogenic Interaction between Intracellular Amyloid-β and Apolipoprotein-E
Arpan Dey, Aditi Verma, Uchit Bhaskar, Bidyut Sarkar, Mamata Kallianpur, Vicky Vishvakarma, Anand Kant Das, Kanchan Garai, Odity Mukherjee, Kunihiko Ishii et al. · 2024 · ACS Chemical Neuroscience
Whole-genome sequencing reveals the impact of lipid pathway and APOE genotype on brain amyloidosis
Maulikkumar Patel, Cyril P. Pottier, Kang-Hsien Fan, Arda Cetin, Matthew Johnson, Muhammad Ali, Menghan Liu, Priyanka Gorijala, John Budde, Ruyu Shi et al. · 2025 · Human Molecular Genetics
APOE deficiency inhibits amyloid-facilitated (A) tau pathology (T) and neurodegeneration (N), halting progressive ATN pathology in a preclinical model
Sarah Vanherle, Art Janssen, Manuel Gutiérrez de Ravé, Bieke Janssen, Chritica Lodder, Pablo Botella Lucena, Sofie Kessels, Jana Hardy, Eline Vandeput, Yanyan Wang et al. · 2025 · Molecular Psychiatry
Mathematical aspects of the kinetics of formation and degradation of linear peptide or protein aggregates
Vladimir P. Zhdanov · 2016 · Mathematical Biosciences
Compilation and Analysis of Enzymes, Engineered Antibodies, and Nanoparticles Designed to Interfere with Amyloid‐β Aggregation
Jun Zhao, Buyong Ma, Ruth Nussinov · 2016 · Israel Journal of Chemistry
Role of endolysosomes and cholesterol in the pathogenesis of Alzheimer's disease: Insights into why statins might not provide clinical benefit.
Xuesong Chen, Hui Liang, Jonathan D. Geiger · 2014 · PubMed
Association Study of Apolipoprotein E Gene Polymorphism With Incidence and Delayed Resolution of Hemifacial Spasm
Jianxin Zhou, Li Jiang, Sangui Yuan, Jiashang Huang, Quanhong Shi, Yanfeng Xie, Bo Deng, Yan Zhan · 2021 · Frontiers in Neurology
Micelles-based drug delivery for dementia
Oly Katari, Sheetal Yadav, Junia Akhtar, Sanyog Jain · 2022 · Elsevier eBooks
Associations Between Levels of Peripheral NCAPH2 Promoter Methylation and Different Stages of Alzheimer’s Disease: A Cross-Sectional Study
Shuwen Hao, Tao-Ran Li, Chao Han, Ying Han, Yan-Ning Cai · 2023 · Journal of Alzheimer's Disease
Adaptive immune changes associate with clinical progression of Alzheimer’s disease
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APOE genetic variability in an Egyptian cohort of PD
Eman Mohamed Khedr, Martina B. William, Aliaa A Elhosseiny, Ali Shalash, Gharib Fawi, Mohamed H. Yousef, Shaimaa Ibrahim El-Jaafary, Hamin Lee, Alina Jama, Mohamed Koraym et al. · 2025 · Frontiers in Neuroscience
Investigating the Effect of Human APOE Gene on Mitochondrial Dynamics of Nervous System Cells in Drosophila Models of Alzheimer’s Disease
Asma Mirkamali, Samaneh Reiszadeh Jahromi · 2025 · Russian Journal of Genetics
Preexisting Genetic Background Primes the Responses of Human Neurons to Amyloid β
Adedamola Saidi Soladogun, Zhang Li · 2025 · International Journal of Molecular Sciences
Microbiota gut-brain axis dysfunction in Alzheimer’s Disease: From pathogenesis to potential treatments – A review
Bilal Salman, Rima Haidar, Vivian Faour, Wissam Abou Ali, Lea Aridi, Frédéric Harb, Sami T. Azar, Ziad Abi Khattar, Hilda E. Ghadieh · 2025 · Health Sciences Review
Age-related macular degeneration and cerebral amyloid angiopathy have similar pathologies from cholesterol-APOE-amyloid-β-complement mediated inflammation
W. Sambhariya, Catherine Bowes Rickman, P. A. d’Amore, G. Corradetti, G. S. Hageman, Gareth R. Howell, Olivia J. Marola, H. Phatnani, N. Philp, Debasish Sinha et al. · 2026 · Progress in retinal and eye research
Apolipoprotein E in Alzheimer's disease: A review of APOE receptors, signalling pathways and therapeutic opportunities
J. Saravanan, Vigneshwaran Easwaran, Divakar Selvaraj, Venkatesh Gunasekaran, V. Soumya, M. Thiruselvi, M. Laxmana Prasanth, Siddharth Singh, C. Ellaiyarasu, P. Karthik Rai et al. · 2026 · Molecular and Cellular Neuroscience
Nontargeted Metabolite Profiling of Induced Pluripotent Stem Cells (iPSCs) Derived Neural Cells: Insights Into Mechanisms of Brain Diseases
Šárka Lehtonen, Marko Lehtonen, Jari Koıstınaho · 2016 · InTech eBooks
Vigour of CRISPR/Cas9 Gene Editing in Alzheimer’s Disease
Paul Jes · 2018 · Journal of Neuroscience and Neurological Disorders
Is the controversy between Baptists and Tauists still present?
Anisha Bhola, Kameev Sharma, Shampa Ghosh, Dr. Krishna Kumar Singh, Rakesh Bhaskar, Jitendra Kumar Sinha · 2024 · Elsevier eBooks
Further study of the rôle played by fluorine in the causation of disease.
Leo Spira · 1952 · PubMed
APOE4 expression confers a mild, persistent reduction in neurovascular function in the visual cortex and hippocampus of awake mice
Orla Bonnar, Kira Shaw, Dori M. Grijseels, Devin Clarke, Laura Bell, Silvia Anderle, Sarah L. King, Catherine N. Hall · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
APOEe4.Trem2*R47H Mice Show Changes in Alzheimer’s Disease-Relevant Processes in the Absence of Amyloid Plaques
Kevin P. Kotredes, Adrian L. Oblak, Ravi S. Pandey, Peter Bor‐Chian Lin, Dylan T. Garceau, Harriet M. Williams, Asli Uyar, Rita O’Rourke, Sarah O’Rourke, Cynthia M. Ingraham et al. · 2021 · Research Square
ABCA1 activity is associated with reduced Alzheimer’s Disease risk in APOE ε4 non-carriers
Andrés Peña‐Tauber, Ricardo Hernández Arriaza, Yann Le Guen, Jun Young Park, Michael D. Greicius · 2025 · medRxiv
ApoE lipidation, not isoform, is the key modulator of Aβ interaction, uptake, and cytotoxicity
Kamila Nurmakova, Gregory-Neal W Gomes, Zachary A. Levine · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
Genetics and Pathology of Chronic Traumatic Encephalopathy
Laura L. Krafjack, Ramesh Raghupathi · 2015 · Current Genetic Medicine Reports
Human APOE4 affects microglial reactivity and spatial cognition in a mouse model of alzheimer's disease risk
Gustavo A. Rodriguez · 2014 · DigitalGeorgetown (Georgetown University Library)
Brain Aging as a Cause of Alzheimer’s Disease
Toshiharu Suzuki, Ayano Kimura, Kyoko Chiba, Tadashi Nakaya, Saori Hata · 2015 · Springer eBooks
Effect of liver x receptor target genes Apolipoprotein E and ATP-binding cassette transporter A1 on beta-amyloid dependent pathology in Alzheimer's disease model mice
Alexis B. Carter · 2017 · D-Scholarship@Pitt (University of Pittsburgh)
Magnetic resonance imaging and spectroscopy in at-risk populations and preclinical Alzheimer's disease
Olga Voevodskaya · 2018 · Figshare
Investigating alterations in autophagy in Alzheimer’s disease using human brain tissue and skin-derived fibroblasts
Diana Madalina Stan · 2018 · University of Salford Institutional Repository (University of Salford)
AXL receptor tyrosine kinase regulates Apolipoprotein E expression
Wenchen Zhao · 2019 · cIRcle (University of British Columbia)
Fact, Fiction, or Evolution: Mechanism Hypothesis of Alzheimer’s Disease
José V. Pardo · 2019 · IntechOpen eBooks
Ageing in Better Mental Health
Marisa Cordella, Aldo Poiani · 2021 · International perspectives on aging
APOE ε4 allele advances the age-dependent decline of amyloid β clearance in the human cortex
Atsushi Saito, Yusuke Kageyama, Olga Pletniková, Gay L. Rudow, Yang An, Yumi Irie, Akiko Kita, Kunio Miki, Ling Li, Pamela E. Southall et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
ApoE4 and the Clinical Outcomes and Pathophysiology of Degenerative Cervical Myelopathy: Evidence from Human Data and Mouse Models
Alexa Maria Lena Desimone · 2021 · TSpace (University of Toronto)
Perivascular drainage of amyloid beta (Aβ) and waste products from the brain and its failure.
Nikola Barić · 2020
The APOE4 Mouse as a Model of Chemotherapy-induced Cognitive Impairments and Senescence
Tamar C. Demby · 2021 · DigitalGeorgetown (Georgetown University Library)
Alzheimer’s disease as a syndrome of overloaded amyloidic synaptic tagging in memory networks
Niall Murphy · 2021
Understanding Alzheimer’s Risk Factors Associated with the Prevalence of US Populations and Women
Krrishika Saxena, Sabin A. Nettles · 2022 · Journal of Student Research
Single-Cell Analysis of the Peripheral Immune Landscape in Alzheimer's Disease Reveals a Distinct Adaptive Immune Signature
Lynn van Olst, Susanne M. A. van der Pol, Alwin Kamermans, Inge M.W. Verberk, Danielle W.R. Wessels, Sanne G. S. Verberk, E. Rodriguez, Carla Rodriguez-Mogeda, Jan Verhoeff, Dirk Wouters et al. · 2022 · SSRN Electronic Journal
The Role of Impaired Receptor Trafficking in Mediating the Pathological Effects of ApoE4 in Alzheimer Disease
Mirna Safieh, Ori Liraz, Maayan Ovadia, Danny M. Michaelson · 2022 · Research Square
Apolipoprotein-E transforms intracellular Amyloid-β oligomers to a more toxic state
Arpan Dey, Aditi Verma, Uchit Bhaskar, Bidyut Sarkar, Mamata Kallianpur, Vicky Vishvakarma, Anand Kant Das, Kanchan Garai, Odity Mukherjee, Kunihiko Ishii et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
Human Apolipoprotein E Impairs Csga-Amyloid and Biofilm Formation of E. Coli UTI89
Sanduni Wasana Jayaweera, Anthony Balistreri, Elizabeth Gichana, Elisa Pierre, Si Lhyam Myint, Sun Nyunt Wai, Mark A. Gomulinski, Matthew R. Chapman, Anders Olofsson · 2023 · SSRN Electronic Journal
APOE regulates the transport of GM1
Dong Yan Zhang, Jian Wang, Gangtong Huang, Sara Langberg, Feng Ding, Nikolay V. Dokholyan · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Additional file 1 of CSF biomarker analysis of ABCA7 mutation carriers suggests altered APP processing and reduced inflammatory response
Lena Duchateau, Fahri Küҫükali, Arne De Roeck, Mandy Melissa Jane Wittens, Joke Temmerman, Ilse Weets, Maarten Timmers, Sebastiaan Engelborghs, Maria Bjerke, Kristel Sleegers · 2023 · Figshare
Additional file 2 of Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance
Weixi Feng, Yanli Zhang, Ze Wang, Hanrong Xu, Ting Wu, Charles Marshall, Junying Gao, Ming Xiao · 2020 · Figshare
DiGAS: Differential gene allele spectrum as a descriptor in genetic studies
Antonino Aparo, Vincenzo Bonnici, Simone Avesani, Luciano Cascione, Rosalba Giugno · 2024 · Computers in Biology and Medicine
Understanding the effect of oAβ and oTau proteins on impaired LTP within Alzheimer’s Disease
Shantala Totada, Debra Abramov · 2024 · Journal of Student Research
Epigenomic anomalies in induced pluripotent stem cells from Alzheimer’s disease cases
Anthony Flamier, Alisar Katbe, Dounya Serhani, Rimi Hamam, Ryan Hogan, Erika Sendra Tavares, Elise Héon, Roy Hanna, Gilbert Bernier · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
Relationship Between Dyslipidemia and Alzheimer’s Disease
Murat Bolayırlı, Mine Kücür · 2024
Chronic Traumatic Encephalopathy: A Comprehensive Narrative Review of Its Biomarkers
A. M. A. Majeed, Nageen Naz, FNU Namal, Sohaira Tahir, Vikash Kumar Karmani · 2024 · Cureus
The Liver–Gut–Brain Axis and Hepatic Encephalopathy
Natalia A. Osna, Larisa Y. Poluektova, Kusum K. Kharbanda · 2024 · Springer eBooks
Differential Effects of Aβ Peptides on the Plasmin-Dependent Degradation of ApoE3 and ApoE4.
Merc M Kemeh, Anthony J Furnelli, Noel D Lazo · 2025 · ACS Chemical Neuroscience
Psychoneuroimmunology in the Context of Dementia
Shilpa Borehalli Mayegowda, Sacheth Kiran Donni, Aditi Patnaik, Kevin Prince · 2025 · Advances in medical diagnosis, treatment, and care (AMDTC) book series
Co-Deposited Proteins in Alzheimer’s Disease as a Potential Treasure Trove for Drug Repurposing
Avgi E. Apostolakou, Dimitra E. Douska, Zoi I. Litou, Ioannis P. Trougakos, Vassiliki A. Iconomidou · 2025 · Molecules
Anti-Amyloid Agents: A Self-Fulfilling prophecy
Alexandros Giannakis, Spiridon Konitsiotis · 2025 · Journal of Clinical Neuroscience
Gene Therapy Against Age-Related Diseases
Riya Rameshwar Rai, Sagar Hindurao Barage, Rajshri Singh · 2025 · IGI Global eBooks
APOE ε4‐independent pathways predominate in the association between retinal nerve fiber layer thinning and 12‐year incident dementia
Yuzhuo Wang, Xiaoxi Ma, Haoze Cen, Jie Wang, Jie Wu, Ding Ding, Yiqin Xiao, Qianhua Zhao · 2025 · Alzheimer s & Dementia Translational Research & Clinical Interventions
Serum tyrosine associates with increased CSF Aβ42, reduced Aβ deposition, and cognitive improvement in MCI: modulation by confounding factors
Shahad Mohammed Dhiaa Younis, Abdulkareem Shareef, Ashok Kumar Bishoyi, R. Roopashree, Aditya Kashyap, Atreyi Pramanik, Subhashree Ray, МАВЛЯНОВА Зилола Фархадовна, Hayder Naji Sameer, Ahmed Yaseen et al. · 2025 · International Journal of Neuroscience
The Crosstalk Between Non-Coding RNAs and Lipid Metabolism in Chronic Disease Progression
Zoofa Zayani, Arash Matinahmadi, Alireza Tavakolpournegari, Seyedeh Safoora Moosavi, Seyed Hesamoddin Bidooki · 2025 · Lipidology
APOE4-APP interactions exert early influences on cerebrovascular structure and function: implications for Alzheimer’s disease
Lanboling Guo, Jessica Ruth Gaunt, Calvin Chee Hoe Cheah, Albert I. Chen, Stephanie Claudine, Gavin Stewart Dawe, Eyleen Lay Keow Goh, Sok-Hong Kho, Pawan Kumar, Grace G. Y. Lim et al. · 2025 · Frontiers in Neuroscience
Antibodies targeting amyloid-β and Tau oligomers in Alzheimer’s disease
Subashchandrabose Chinnathambi, Nagaraj Rangappa, Madhura Chandrashekar · 2025 · Advances in protein chemistry and structural biology
Role of diabetes and altered metabolic homeostasis in age-related dementia
Tannishtha Biswas, Mehnaz Atiq Ahmed, Sramana Bhowmick, Susmita Mondal · 2025 · Elsevier eBooks
Additional file 14 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 4 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 1 of APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12
Jordy Sepulveda, Jennifer Yejean Kim, Joseph Binder, Stefano Vicini, George William Rebeck · 2024 · Figshare
Additional file 10 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 3 of APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12
Jordy Sepulveda, Jennifer Yejean Kim, Joseph Binder, Stefano Vicini, George William Rebeck · 2024 · Figshare
Additional file 15 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 5 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 21 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 1 of Microglia prevent beta-amyloid plaque formation in the early stage of an Alzheimer’s disease mouse model with suppression of glymphatic clearance
Feng, Weixi, Zhang, Yanli, Ze Wang, Xu, Hanrong, Wu, Ting, Charles Marshall, Gao, Junying, Xiao, Ming · 2020 · Figshare
Additional file 1 of A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
Ana Carolina Valencia‐Olvera, Deebika Balu, Shreya Bellur, Thomas P. McNally, Yaseen Saleh, Pham, Don, Shivesh Ghura, Jason M. York, Jan O. Johansson, Mary Jo LaDu et al. · 2023 · Figshare
Additional file 9 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 11 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 16 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 2 of A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
Ana Carolina Valencia‐Olvera, Deebika Balu, Shreya Bellur, Thomas P. McNally, Yaseen Saleh, Pham, Don, Shivesh Ghura, Jason M. York, Jan O. Johansson, Mary Jo LaDu et al. · 2024 · Figshare
Additional file 18 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, van der Pol, Susanne M. A., Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 4 of A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
Ana Carolina Valencia‐Olvera, Deebika Balu, Shreya Bellur, Thomas P. McNally, Yaseen Saleh, Pham, Don, Shivesh Ghura, Jason M. York, Jan O. Johansson, Mary Jo LaDu et al. · 2024 · Figshare
Additional file 7 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 13 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 2 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 1 of Photoactivation of TGFβ/SMAD signaling pathway ameliorates adult hippocampal neurogenesis in Alzheimer’s disease model
Xiaolei Wu, Qi Shen, Zhan Zhang, Di Zhang, Ying Gu, Xing, Da · 2021 · Figshare
Additional file 8 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 12 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 1 of Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients
Matthew Paul Lennol, Irene Sánchez-Domínguez, Inmaculada Cuchillo‐Ibáñez, Elena Camporesi, Gunnar Brinkmalm, Daniel Andres Alcolea, Juan Fortea, Alberto Lleó, Guadalupe Sòria, Fernando Aguado et al. · 2022 · Figshare
Additional file 1 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 5 of A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
Ana Carolina Valencia‐Olvera, Deebika Balu, Shreya Bellur, Thomas P. McNally, Yaseen Saleh, Pham, Don, Shivesh Ghura, Jason M. York, Jan O. Johansson, Mary Jo LaDu et al. · 2024 · Figshare
Additional file 2 of CSF biomarker analysis of ABCA7 mutation carriers suggests altered APP processing and reduced inflammatory response
Lena Duchateau, Fahri Küҫükali, Arne De Roeck, Mandy Melissa Jane Wittens, Joke Temmerman, Ilse Weets, Maarten Timmers, Sebastiaan Engelborghs, Maria Bjerke, Kristel Sleegers · 2024 · Figshare
Additional file 3 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 20 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 6 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 3 of A novel apoE-mimetic increases brain apoE levels, reduces Aβ pathology and improves memory when treated before onset of pathology in male mice that express APOE3
Ana Carolina Valencia‐Olvera, Deebika Balu, Shreya Bellur, Thomas P. McNally, Yaseen Saleh, Pham, Don, Shivesh Ghura, Jason M. York, Jan O. Johansson, Mary Jo LaDu et al. · 2024 · Figshare
Additional file 2 of APOE4 genotype and aging impair injury-induced microglial behavior in brain slices, including toward Aβ, through P2RY12
Jordy Sepulveda, Jennifer Yejean Kim, Joseph Binder, Stefano Vicini, George William Rebeck · 2024 · Figshare
Additional file 19 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Additional file 17 of Adaptive immune changes associate with clinical progression of Alzheimer’s disease
Lynn van Olst, Alwin Kamermans, Sem Halters, Susanne M. A. van der Pol, Ernesto Rodríguez, Inge M.W. Verberk, Sanne G. S. Verberk, Danielle W.R. Wessels, Carla Rodriguez-Mogeda, Jan Verhoeff et al. · 2024 · Figshare
Biosimilars: Antibody and nanobody-based therapeutic approaches towards protein misfolding diseases
Subashchandrabose Chinnathambi, Nagaraj Rangappa · 2025 · Advances in protein chemistry and structural biology
High-density lipoprotein mimetic peptide 4F ameliorates APOE4-associated lipid dysfunction in primary and iPSC-derived astrocytes and cerebral organoids
Kristina Fredriksen, Siddhi S. Joshi, Allison Chang, Ling Li · 2025 · bioRxiv
Genome-wide association studies identify genetic determinants of synucleinopathy biomarkers
Emma N. Somerville, Lang Liu, Michael Ta, Hirotaka Iwaki, Konstantin A. Senkevich, Roy N. Alcalay, Ziv Gan‐Or · 2025 · Research Square
Probucol attenuates bone loss in APP/PS1 mice and ameliorates Aβ42-induced osteoblast dysfunction by regulating AKT/FOXO3a signaling pathway
D. Liu, Hongyan Yang, Xiangqian Feng, Mingliang Hou, Xiaoyan Fu, X Y Li, Wenjuan Hong, Le Chen, Jinping Li, Linqiu Ma et al. · 2026 · Experimental Gerontology