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Extracellular MicroRNAs Activate Nociceptor Neurons to Elicit Pain via TLR7 and TRPA1

Park, Chul-Kyu, Xu, Zhen-Zhong, Berta, Temugin, Han, Qingjian, Chen, Gang, Liu, Xing-Jun, Ji, Ru-Rong·2014·Neuron
DOI 10.1016/j.neuron.2014.02.011PMC PMC3982230
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Research works printed but not linked: 29

  1. Akira, 2006, Pathogen recognition and innate immunity, Cell, 124, 783, 10.1016/j.cell.2006.02.015 · DOI
  2. Bartel, 2004, MicroRNAs: genomics, biogenesis, mechanism, and function, Cell, 116, 281, 10.1016/S0092-8674(04)00045-5 · DOI
  3. Basbaum, 2009, Cellular and molecular mechanisms of pain, Cell, 139, 267, 10.1016/j.cell.2009.09.028 · DOI · Paper page
  4. Bautista, 2006, TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents, Cell, 124, 1269, 10.1016/j.cell.2006.02.023 · DOI
  5. Caterina, 2001, The vanilloid receptor: a molecular gateway to the pain pathway, Annu. Rev. Neurosci., 24, 487, 10.1146/annurev.neuro.24.1.487 · DOI
  6. Eacker, 2009, Understanding microRNAs in neurodegeneration, Nat. Rev. Neurosci., 10, 837, 10.1038/nrn2726 · DOI · Paper page
  7. Fabbri, 2012, MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response, Proc. Natl. Acad. Sci. USA, 109, E2110, 10.1073/pnas.1209414109 · DOI · Paper page
  8. Heil, 2004, Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8, Science, 303, 1526, 10.1126/science.1093620 · DOI · Paper page
  9. Hucho, 2007, Signaling pathways in sensitization: toward a nociceptor cell biology, Neuron, 55, 365, 10.1016/j.neuron.2007.07.008 · DOI
  10. Jordt, 2004, Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1, Nature, 427, 260, 10.1038/nature02282 · DOI
  11. Kang, 2010, Analysis of Drosophila TRPA1 reveals an ancient origin for human chemical nociception, Nature, 464, 597, 10.1038/nature08848 · DOI
  12. Lehmann, 2012, An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration, Nat. Neurosci., 15, 827, 10.1038/nn.3113 · DOI · Paper page
  13. Liu, 2013, New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?, Pflugers Arch., 465, 1671, 10.1007/s00424-013-1284-2 · DOI
  14. Liu, 2010, Toll-like receptor 7 mediates pruritus, Nat. Neurosci., 13, 1460, 10.1038/nn.2683 · DOI
  15. Liu, 2012, TLR3 deficiency impairs spinal cord synaptic transmission, central sensitization, and pruritus in mice, J. Clin. Invest., 122, 2195, 10.1172/JCI45414 · DOI
  16. Liu, 2012, Emerging role of Toll-like receptors in the control of pain and itch, Neurosci. Bull., 28, 131, 10.1007/s12264-012-1219-5 · DOI
  17. Macpherson, 2007, Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines, Nature, 445, 541, 10.1038/nature05544 · DOI
  18. McNamara, 2007, TRPA1 mediates formalin-induced pain, Proc. Natl. Acad. Sci. USA, 104, 13525, 10.1073/pnas.0705924104 · DOI
  19. Orlova, 2011, MicroRNA modulation in complex regional pain syndrome, J. Transl. Med., 9, 195, 10.1186/1479-5876-9-195 · DOI
  20. Pasquinelli, 2000, Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA, Nature, 408, 86, 10.1038/35040556 · DOI
  21. Patapoutian, 2009, Transient receptor potential channels: targeting pain at the source, Nat. Rev. Drug Discov., 8, 55, 10.1038/nrd2757 · DOI
  22. Qin, 2008, TRPV2 is activated by cannabidiol and mediates CGRP release in cultured rat dorsal root ganglion neurons, J. Neurosci., 28, 6231, 10.1523/JNEUROSCI.0504-08.2008 · DOI
  23. Reinhart, 2000, The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans, Nature, 403, 901, 10.1038/35002607 · DOI
  24. Schmidt, 2009, Nociceptive signals induce trafficking of TRPA1 to the plasma membrane, Neuron, 64, 498, 10.1016/j.neuron.2009.09.030 · DOI
  25. Story, 2003, ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures, Cell, 112, 819, 10.1016/S0092-8674(03)00158-2 · DOI
  26. Takeuchi, 2010, Pattern recognition receptors and inflammation, Cell, 140, 805, 10.1016/j.cell.2010.01.022 · DOI · Paper page
  27. von Schack, 2011, Dynamic changes in the microRNA expression profile reveal multiple regulatory mechanisms in the spinal nerve ligation model of neuropathic pain, PLoS ONE, 6, e17670, 10.1371/journal.pone.0017670 · DOI
  28. Woolf, 2007, Nociceptors—noxious stimulus detectors, Neuron, 55, 353, 10.1016/j.neuron.2007.07.016 · DOI
  29. Zhao, 2010, Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds, J. Neurosci., 30, 10860, 10.1523/JNEUROSCI.1980-10.2010 · DOI

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Metadata

Authors
Park, C.-K., Xu, Z.-Z., Berta, T., Han, Q., Chen, G., Liu, X.-J., & Ji, R.-R.
Venue
Neuron
Publisher
Elsevier BV
Published
2014-04
Volume
82
Issue
1
Pages
47-54
ISSN
0896-6273
DOI
10.1016/j.neuron.2014.02.011
PMC
PMC3982230
Cited by
289
References
0
Language
en
Licence

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