The DOI matches its Crossref record; 314 of the 314 references it cites were found in a registry or an index.
Neuregulin-ERBB Signaling in the Nervous System and Neuropsychiatric Diseases
Open accessAbstract
Summary Neuregulins (NRGs) comprise a large family of growth factors that stimulate ERBB receptor tyrosine kinases. NRGs and their receptors ERBBs have been identified as susceptibility genes for diseases such as schizophrenia (SZ) and bipolar disorder. Recent studies have revealed complex Nrg/Erbb signaling networks that regulate the assembly of neural circuitry, myelination, neurotransmission and synaptic plasticity. Evidence indicates there is an optimal level of NRG/ERBB signaling in the brain and deviation from it impairs brain functions. NRGs/ERBBs and downstream signaling pathways may provide therapeutic targets for specific neuropsychiatric symptoms.
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Metadata
- Authors
- Mei, L., & Nave, K.-A.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2014-07
- Volume
- 83
- Issue
- 1
- Pages
- 27-49
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2023527463
- Cited by
- 592
- References
- 314
- FWCI
- 21.40
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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