Circuit-wide Transcriptional Profiling Reveals Brain Region-Specific Gene Networks Regulating Depression Susceptibility

Bagot, Rosemary C., Cates, Hannah M., Purushothaman, Immanuel, Lorsch, Zachary S., Walker, Deena M., Wang, Junshi, Huang, Xiaojie, Schlüter, Oliver M. +17 more·2016·Neuron
DOI 10.1016/j.neuron.2016.04.015

Cited by (334)

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  59. Distinct molecular mechanisms of stress habituation in the mouse hippocampus
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  85. Universal Transcriptional Responses to Different Modalities of Traumatic Stress as a Measure of Stress Exposure
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  91. Transcription factor activity profiling reveals the role of REST and LEF1 in the recovery from depression
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  93. Challenges for Intervention Research Within the GEX Framework
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  94. A convergent depression vulnerability pathway encoded by emergent spatiotemporal dynamics
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