Tau Kinetics in Neurons and the Human Central Nervous System
Sato, Chihiro, Barthélemy, Nicolas R., Mawuenyega, Kwasi G., Patterson, Bruce W., Gordon, Brian A., Jockel-Balsarotti, Jennifer, Sullivan, Melissa, Crisp, Matthew J. +9 more·2018·Neuron
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- Regional correlation of biochemical measures of amyloid and tau phosphorylation in the brainKanta Horie, Nicolas R. Barthélemy, Nipun Mallipeddi, Yan Li, Erin E. Franklin, Richard J. Perrin, Randall John Bateman, Chihiro Sato · 2020 · Acta Neuropathologica Communications
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