MicroRNAs on the move: microRNAs in astrocyte-derived ApoE particles regulate neuronal function

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

Vickers, K. C., Palmisano, B. T., Shoucri, B. M., Shamburek, R. D., & Remaley, A. T. (2011) · Nature Cell Biology · doi:10.1038/ncb2210 · Cited by 2,741 · see citing works

MicroRNAs in body fluids—the mix of hormones and biomarkers

Cortez, M. A., Bueso-Ramos, C., Ferdin, J., Lopez‐Berestein, G., Sood, A. K., & Călin, G. A. (2011) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2011.76 · Cited by 1,471 · see citing works

Haploinsufficiency of Human APOE Reduces Amyloid Deposition in a Mouse Model of Amyloid-β Amyloidosis

Kim, J., Jiang, H., Park, S., Eltorai, A. E. M., Stewart, F. R., Yoon, H., Basak, J. M., Finn, M. B., & Holtzman, D. M. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.3773-11.2011 · Cited by 199 · see citing works

Apolipoprotein E metabolism and functions in brain and its role in Alzheimer's disease

Liao, F., Yoon, H., & Kim, J. (2017) · Current Opinion in Lipidology · doi:10.1097/mol.0000000000000383 · Cited by 191 · see citing works

Reducing Human Apolipoprotein E Levels Attenuates Age-Dependent Aβ Accumulation in Mutant Human Amyloid Precursor Protein Transgenic Mice

Bien-Ly, N., Gillespie, A. K., Walker, D., Yoon, S. Y., & Huang, Y. (2012) · The Journal of Neuroscience · doi:10.1523/jneurosci.0033-12.2012 · Cited by 170 · see citing works

Astrocytic ApoE reprograms neuronal cholesterol metabolism and histone-acetylation-mediated memory

Li, X., Zhang, J., Li, D., He, C., He, K., Xue, T., Wan, L., Zhang, C., & Liu, Q. (2021) · Neuron · doi:10.1016/j.neuron.2021.01.005 · Cited by 165 · see citing works

miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling

Kim, W., Lee, Y., McKenna, N. D., Yi, M., Šimunović, F., Wang, Y., Kong, B., Rooney, R. J., Seo, H., Stephens, R. M., et al. (2014) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2014.01.021 · Cited by 147 · see citing works

Anti-ApoE Antibody Given after Plaque Onset Decreases Aβ Accumulation and Improves Brain Function in a Mouse Model of Aβ Amyloidosis

Liao, F., Hori, Y., Hudry, E., Bauer, A. Q., Jiang, H., Mahan, T. E., Lefton, K. B., Zhang, T. J., Dearborn, J. T., Kim, J., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.0646-14.2014 · Cited by 128 · see citing works

Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice

Lane-Donovan, C., Wong, W. M., Durakoglugil, M. S., Wasser, C. R., Jiang, S., Xian, X., & Herz, J. (2016) · The Journal of Neuroscience · doi:10.1523/jneurosci.1054-16.2016 · Cited by 115 · see citing works

MiR-126 Regulates Growth Factor Activities and Vulnerability to Toxic Insult in Neurons

Kim, W., Noh, H., Lee, Y., Jeon, J., Shanmugavadivu, A., McPhie, D. L., Kim, K., Cohen, B. M., Seo, H., & Sonntag, K. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8989-x · Cited by 56 · see citing works

Astrocytic microRNAs and transcription factors in Alzheimer’s disease and therapeutic interventions

Nassar, A., Kodi, T., Satarker, S., Chowdari Gurram, P., Upadhya, D., SM, F., Mudgal, J., & Nampoothiri, M. (2022) · Cells · doi:10.3390/cells11244111 · Cited by 36 · see citing works

MAD—microbial (origin of) Alzheimer’s disease hypothesis: from infection and the antimicrobial response to disruption of key copper-based systems

Min, J.-H., Sarlus, H., & Harris, R. A. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1467333 · Cited by 11 · see citing works

Unveiling the Role of Novel miRNA PC-5P-12969 in Alleviating Alzheimer’s Disease

Vijayan, M., & Reddy, P. H. (2024) · Journal of Alzheimer s Disease · doi:10.3233/jad-231281 · Cited by 4 · see citing works

Astrocyte lactoferrin deficiency affects the construction and function of spinal neurons by regulating cholesterol metabolism

Tong, X., Liu, X., Jiang, Y., Su, J., Luan, J.-Q., & Guo, C. (2025) · Experimental Cell Research · doi:10.1016/j.yexcr.2025.114595

Lenism: A Novel Biopsychosocial-Philosophical Framework for Right-Brain Dominance as a Leverage Point for Creative Problem-Solving and Human Thriving in Society

Ogunlade, O. (2025) · International Journal of Psychological and Brain Sciences · doi:10.11648/j.ijpbs.20251002.11

Apolipoprotein E as a therapeutic target in Alzheimer's disease: A review of basic research and clinical evidence

Kaur, A., Murthy, S., Bharath Kumar, D. R., Gokulakrishnan, S., Philantharopa, U. P. B., & Narajji, C. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40563-1.00010-7

APOE ε3/ε4 and APOE ε4/ε4 genotypes drive unique gene signatures in the cortex of young micePreprint

Foley, K. E., Garceau, D. T., Kotredes, K. P., Carter, G. W., Sasner, M., & Howell, G. R. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.28.359422 · Cited by 3 · see citing works

Apolipoprotein E Genotype Affects Size of ApoE Complexes in Cerebrospinal Fluid

Heinsinger, N. M., Gachechiladze, M. A., & Rebeck, G. W. (2016) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlw067 · Cited by 74 · see citing works

The Recycling of Apolipoprotein E in Primary Cultures of Mouse Hepatocytes

Farkas, M. H., Swift, L. L., Hasty, A. H., Linton, M. F., & Fazio, S. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m208026200 · Cited by 46 · see citing works

The Expression of Apolipoprotein E in Osteoblastic Cells on Titanium

Ishibe, T., Goto, T., Kawata, K., et al. (2009) · The Journal of the Kyushu Dental Society · doi:10.2504/kds.63.78

Astrocyte-mediated control of cerebral microcirculation

Anderson, C. M., & Nedergaard, M. (2003) · Trends in Neurosciences · doi:10.1016/s0166-2236(03)00141-3 · Cited by 183 · see citing works