Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease.

Cited by (439)

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  49. Additional file 1 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
  50. Additional file 3 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
  51. Additional file 2 of Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy
    Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, Perez, Sylvia, He, Bin, Stephen D. Ginsberg, Mullan, Michael et al. · 2024 · Figshare
  52. Additional file 1 of Neuroimmune proteins can differentiate between tauopathies
    Jonathan D. Cherry, Zach H. Baucom, Kaleb G. Eppich, Daniel A Kirsch, Erin Dixon, Yorghos Tripodis, Kevin F. Bieniek, Kurt W. Farrell, Kristen R. Whitney, Madeline Uretsky et al. · 2022 · Figshare
  53. Additional file 5 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  54. Additional file 7 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  55. Additional file 5 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
  56. Additional file 1 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Jieqiong Xie, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  57. Additional file 2 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  58. Additional file 8 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  59. Additional file 4 of Altered glia-neuron communication in Alzheimer’s Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq
    Tabea M. Soelter, Timothy C. Howton, Amanda D. Clark, Vishal H. Oza, Brittany N. Lasseigne · 2024 · Figshare
  60. Additional file 1 of IFNγ drives neuroinflammation, demyelination, and neurodegeneration in a mouse model of multiple system atrophy
    Nicole J Corbin-Stein, Gabrielle M. Childers, Jhodi M. Webster, Asta Zane, Yang, Ya-Ting, Nikhita Mudium, Gupta, Rajesh, Fredric P. Manfredsson, Kordower, Jeffrey H., Ashley S. Harms · 2024 · Figshare
  61. Additional file 4 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
  62. Additional file 1 of Altered glia-neuron communication in Alzheimer’s Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq
    Tabea M. Soelter, Timothy C. Howton, Amanda D. Clark, Vishal H. Oza, Brittany N. Lasseigne · 2024 · Figshare
  63. Additional file 1 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
  64. Additional file 1 of Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy
    Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, Perez, Sylvia, He, Bin, Stephen D. Ginsberg, Mullan, Michael et al. · 2024 · Figshare
  65. Additional file 9 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  66. Additional file 10 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  67. Additional file 6 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  68. Additional file 8 of Regulatory T cells decrease C3-positive reactive astrocytes in Alzheimer-like pathology
    Grégoire Stym‐Popper, Karen Matta, Thomas Chaigneau, Roshan Rupra, Alexandros Demetriou, Stéphane Fouquet, Cira Dansokho, Cécile Toly‐Ndour, Guillaume Dorothée · 2023 · Figshare
  69. Additional file 5 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  70. Additional file 7 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  71. Additional file 1 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  72. Additional file 6 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  73. Additional file 3 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  74. Additional file 4 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  75. Additional file 3 of Localized microglia dysregulation impairs central nervous system myelination in development
    Rebecca K. Holloway, Zhang, Liang, Irene Molina-González, Kathy Ton, Nicoll, James A. R., Boardman, James P., Yan Liang, Anna Williams, Miron, Veronique E. · 2024 · Figshare
  76. Additional file 2 of Altered glia-neuron communication in Alzheimer’s Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq
    Tabea M. Soelter, Timothy C. Howton, Amanda D. Clark, Vishal H. Oza, Brittany N. Lasseigne · 2024 · Figshare
  77. Additional file 6 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Wang, Chao, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
  78. Additional file 2 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  79. Additional file 2 of Astrocytic APOE4 removal confers cerebrovascular protection despite increased cerebral amyloid angiopathy
    Monica Xiong, Chao Wang, Maud Gratuze, Fareeha Saadi, Bao, Xin, Megan E. Bosch, Choonghee Lee, Hong Jiang, Serrano, Javier Remolina, Ernesto R. Gonzales et al. · 2023 · Figshare
  80. Additional file 3 of Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy
    Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, Perez, Sylvia, He, Bin, Stephen D. Ginsberg, Mullan, Michael et al. · 2024 · Figshare
  81. Additional file 3 of Neuroimmune proteins can differentiate between tauopathies
    Jonathan D. Cherry, Zach H. Baucom, Kaleb G. Eppich, Daniel A Kirsch, Erin Dixon, Yorghos Tripodis, Kevin F. Bieniek, Kurt W. Farrell, Kristen R. Whitney, Madeline Uretsky et al. · 2022 · Figshare
  82. Additional file 4 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  83. Additional file 3 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
  84. Additional file 4 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
  85. Additional file 8 of Single-nucleus analysis reveals microenvironment-specific neuron and glial cell enrichment in Alzheimer’s disease
    Xie, Jieqiong, Lan, Yating, Cuihua Zou, He, Jingfeng, Huang, Qi, Zeng, Jingyi, Mika Pan, Mei, Yujia, Luo, Jiefeng, Zou, Donghua · 2024 · Figshare
  86. Additional file 5 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
  87. Additional file 2 of Neuroimmune proteins can differentiate between tauopathies
    Jonathan D. Cherry, Zach H. Baucom, Kaleb G. Eppich, Daniel A Kirsch, Erin Dixon, Yorghos Tripodis, Kevin F. Bieniek, Kurt W. Farrell, Kristen R. Whitney, Madeline Uretsky et al. · 2022 · Figshare
  88. Additional file 2 of Deciphering glial contributions to CSF1R-related disorder via single-nuclear transcriptomic profiling: a case study
    Jie Pan, Jaume Forés-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Seyed Ahmadian, Euan Angus Ashley, Michael D. Greicius, Inma Cobos · 2024 · Figshare
  89. Additional file 4 of Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy
    Camila Ortiz, Andrew Pearson, Robyn McCartan, Shawn Roche, Nolan Carothers, Mackenzie Browning, Perez, Sylvia, He, Bin, Stephen D. Ginsberg, Mullan, Michael et al. · 2024 · Figshare
  90. Additional file 3 of Altered glia-neuron communication in Alzheimer’s Disease affects WNT, p53, and NFkB Signaling determined by snRNA-seq
    Tabea M. Soelter, Timothy C. Howton, Amanda D. Clark, Vishal H. Oza, Brittany N. Lasseigne · 2024 · Figshare
  91. Brain Region-Specific Oligodendrocyte States Highlight Mitochondrial Gene Upregulation and Loss of Canonical Identity Signatures in Alzheimer’s Disease
    Francesca Drummer, Nadia Dorosti, Charlene-Annett Hurler, Eduardo Beltrán, Louis Benedikt Kuemmerle, Fabian Joachim Theis, Sarah Jäkel · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  92. Dysregulated RNA G-quadruplex binding proteins reveal shifted stress responses in Alzheimer’s Disease
    Xingyu Zhou, Yuanyuan Zhang, Lei Sun, Chun Kit Kwok, Jilin Zhang · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Hopx expression marks Aβ clearance astrocytes in Alzheimer’s disease
    Dong-Dong Cao, Jian Dong, Xiao-Yu Liao, Yang-Yang Teng, Yang Gu, Zhen‐Ge Luo · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
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