The DOI matches its Crossref record; 53 of the 53 references it cites were found in a registry or an index.
Resonance of cortico-cortical connections of the motor system with the observation of goal directed grasping movements
Abstract
Goal directed movements require the activation of parietal, premotor and primary motor areas. In monkeys, neurons of these areas become active also during the observation of movements performed by others, especially for coding the goal of the action (mirror system). Using bifocal transcranial magnetic stimulation (TMS) in healthy subjects, we tested whether the observation of goal directed reach to grasp actions may lead to specific changes in the short-latency connections linking key areas of the mirror system, such as the anterior intraparietal cortex (AIP) and the ventral premotor cortex (PMv), with the primary motor cortex (M1). We found that AIP-M1 and PMv-M1 cortico-cortical interactions were specifically activated when observing successful reaching to grasp goal directed actions, in which the hand posture was congruent with the goal of the action performed by the actor. On the other hand they were not modified when the same goal directed actions were performed wrongly with an inappropriate grasping posture. A similar profile of excitability was observed when testing specific intracortical facilitatory circuits in M1 (I(2)-waves), known to reflect the activity in cortico-cortical pathways transmitting information from PMv. We conclude that the simple observation of others' goal directed actions is able to induce specific neurophysiological changes in some cortico-cortical circuits of the human motor system.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Ventral premotor and parietal regions that are homologous to macaque regions containing mirror neurons have been shown to be causally involved in motor resonance (Avenanti et al., 2007; Koch et al., 2010).”
From To imitate or not: Avoiding imitation involves preparatory inhibition of motor resonance (2014) · cites this paper as Koch et al., 2010
Citations
Cites
The assessment and analysis of handedness: The Edinburgh inventory
Oldfield, R. C. (1971) · Neuropsychologia · doi:10.1016/0028-3932(71)90067-4 · Cited by 35,900
Action recognition in the premotor cortex
Gallese, V., Fadiga, L., Fogassi, L., & Rizzolatti, G. (1996) · Brain · doi:10.1093/brain/119.2.593 · Cited by 4,968
Understanding motor events: a neurophysiological study
di Pellegrino, G., Fadiga, L., Fogassi, L., Gallese, V., & Rizzolatti, G. (1992) · Experimental Brain Research · doi:10.1007/bf00230027 · Cited by 3,539
Neurophysiological mechanisms underlying the understanding and imitation of action
Rizzolatti, G., Fogassi, L., & Gallese, V. (2001) · Nature Reviews Neuroscience · doi:10.1038/35090060 · Cited by 3,302
Corticocortical inhibition in human motor cortex.
Kujirai, T., Caramia, M. D., Rothwell, J. C., Day, B. L., Thompson, P. D., Ferbert, A., Wroe, S. J., Asselman, P., & MARSDEN, C. D. (1993) · The Journal of Physiology · doi:10.1113/jphysiol.1993.sp019912 · Cited by 3,132
Cortical mechanisms of human imitation
Iacoboni, M., Woods, R. P., Brass, M., Bekkering, H., Mazziotta, J. C., & Rizzolatti, G. (1999) · Science · doi:10.1126/science.286.5449.2526 · Cited by 2,683
Action observation activates premotor and parietal areas in a somatotopic manner: an fMRI study
Buccino, G., Binkofski, F., Fink, G. R., Fadiga, L., Fogassi, L., Gallese, V., Seitz, R. J., Zilles, K., Rizzolatti, G., & Freund, H. ‐. (2001) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2001.01385.x · Cited by 2,488
Motor facilitation during action observation: a magnetic stimulation study
Fadiga, L., Fogassi, L., Pavesi, G., & Rizzolatti, G. (1995) · Journal of Neurophysiology · doi:10.1152/jn.1995.73.6.2608 · Cited by 2,297
Action Observation and Acquired Motor Skills: An fMRI Study with Expert Dancers
Calvo‐Merino, B., Glaser, D. E., Grèzes, J., Passingham, R. E., & Haggard, P. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhi007 · Cited by 2,095
Grasping the intentions of others with one's own mirror neuron system
Iacoboni, M., Molnar-Szakacs, I., Gallese, V., Buccino, G., Mazziotta, J. C., & Rizzolatti, G. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030079 · Cited by 2,044 · cited 1×
“…the same parietal and premotor regions during movement observation (Buccino, Binkofski, Fink, Fadiga, & Fogassi, 2001; Calvo-Merino, Glaser, Grèzes, Passingham, & Haggard, 2005; Grafton, Arbib, Fadiga, & Rizzolatti, 1996; Iacoboni et al., 2005; Iacoboni, Woods, Brass, Bekkering, & Mazziotta, 1999).”
Cited by
Sorted by citations
Items 101–119 of 119
Tracking and representing others’ mental states
Butterfill, S. (2017) · Warwick Research Archive Portal (University of Warwick) · doi:10.4324/9781315742250.ch25 · Cited by 1
The Effect of Action Observation Training on Balance and Cognition on the Elderly with Dementia
Kang, C.-J., Son, S.-M., & Park, S. (2024) · The Journal of Korean Physical Therapy · doi:10.18857/jkpt.2024.36.2.61 · Cited by 1
Moriuchi, T., Matsuda, D., Nakamura, J., Matsuo, T., Nakashima, A., Mitsunaga, W., Hasegawa, T., Ikio, Y., Koyanagi, M., & Higashi, T. (2017) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2017.00546 · Cited by 1
Cortical Connections to Motor Cortex and Their Modulation in Behavioural Tasks
Koch, G. (2012) · Springer eBooks · doi:10.1007/978-3-642-32767-4_8
Self-citationYour emotion moves into my motor system
Borgomaneri, S. (2015) · UvA-DARE (University of Amsterdam)
Mirror Neuron Formation via Associative Learning
Catmur, C. (2016) · Cambridge University Press eBooks · doi:10.1017/cbo9781107279353.023
da Silva, R. L., de Souza, Â. M. C., Santos, F. F., Inoue, S. T., Higgins, J., & Frak, V. (2018) · Brain Sciences · doi:10.3390/brainsci8050078
Krawinkel, L. A., Forisch, J., Feldheim, J. F., Backhaus, W., Quandt, F., & Gerloff, C. P. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/525584
Neural Mechanisms Underlying Action with Mirror Visual Feedback
Jegatheeswaran, G. (2019) · TSpace (University of Toronto)
Bunday, K. L., Bonaiuto, J. J., Betti, S., Orban, G. A., & Davare, M. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/743351 · Cited by 1
Anatomy and Physiology of the Mirror Neuron System
Fadiga, L., Tia, B., & Viaro, R. (2015) · Elsevier eBooks · doi:10.1016/b978-0-12-397025-1.00240-2 · Cited by 2
Padova: la rete stradale extraurbana e gli accesi urbani
Madugno, I. (1997) · Quaderni di archeologia del Veneto
Ertelt, D., & Binkofski, F. (2011) · Springer eBooks · doi:10.1007/978-3-642-17257-1_12
Structure of the Motor Descending Pathways Correlates with the Temporal Kinematics of Hand Movements
Begliomini, C., Ceccarini, F., Dell’Acqua, V. P., Budisavljević, S., & Castiello, U. (2022) · Biology · doi:10.3390/biology11101482
Sensorimotor integration during grasping is mediated by distinct M1 circuits
Botta, K., Dolfini, E., Casarotto, A., Koch, G., D’Ausilio, A., & Fadiga, L. (2025) · Journal of Neurophysiology · doi:10.1152/jn.00189.2025
Self-citationSpatiotemporal Brain Dynamics of Transitive and Intransitive Action Observation
Guidali, G., Arrigoni, E., Maravita, A., Pisoni, A., & Bolognini, N. (2026) · Human Brain Mapping · doi:10.1002/hbm.70623
Metadata
- Authors
- Koch, G., Versace, V., Bonnì, S., Lupo, F., Gerfo, E. L., Oliveri, M., & Caltagirone, C.
- Affiliations
- University of Rome Tor Vergata (IT)
- Fondazione Santa Lucia (IT)
- Corresponding author
- Koch, Giacomo
- Venue
- Neuropsychologia
- Publisher
- Elsevier BV
- Published
- 2010-10
- Volume
- 48
- Issue
- 12
- Pages
- 3513-3520
- ISSN
- 0028-3932 (ISSN-L)
- OpenAlex
- W2043841604
- Cited by
- 119
- References
- 53
- Citations by year
- 2026: 2 · 2025: 9 · 2024: 4 · 2023: 2 · 2022: 4 · 2021: 3 · 2020: 8 · 2019: 7 · 2018: 7 · 2017: 6 · 2016: 8 · 2015: 14 · 2014: 12 · 2013: 11 · 2012: 10
- FWCI
- 13.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Neuropsychologia (publishedVersion)
- PubMed (publishedVersion)
- Cineca Institutional Research Information System (Tor Vergata University) (submittedVersion)
- BOA (University of Milano-Bicocca) (submittedVersion)
- Nova Science Publishers (Nova Science Publishers, Inc.) (submittedVersion)
- Institutional Research Information System University of Ferrara (University of Ferrara) (submittedVersion)
- Topics
- Social Sciences › Psychology › Social Psychology › Action Observation and Synchronization
- Life Sciences › Neuroscience › Neurology › Transcranial Magnetic Stimulation Studies
- Life Sciences › Neuroscience › Cognitive Neuroscience › Motor Control and Adaptation
- Keywords
- mirror system, corticocortical connections, ventral premotor cortex, primary motor cortex, action observation
- MeSH terms
- Adult, Brain Mapping, Cerebral Cortex, Electromyography, Female, Goals, Humans, Male, Movement, Neural Pathways, Photic Stimulation, Psychomotor Performance, Muscle, Skeletal, Hand Strength, Evoked Potentials, Motor, Observation, Transcranial Magnetic Stimulation, Young Adult
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
