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Cited by 483Glaucoma and retinal disordersOphthalmology and Visual Impairment StudiesCorneal surgery and disorders

Prevalence of open-angle glaucoma and ocular hypertension in Latinos

Varma, Rohit, Ying-Lai, Mei, Francis, Brian A, Nguyen, Betsy Bao-Thu, Deneen, Jennifer, Wilson, M.Roy, Azen, Stanley P·2004·Ophthalmology
DOI 10.1016/j.ophtha.2004.01.025
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Abstract

Objective To estimate age- and gender-specific prevalences of ocular hypertension and open-angle glaucoma (OAG) in adult Latinos.Design Population-based, cross-sectional study.Participants Six thousand three hundred fifty-seven Latinos 40 years and older from 6 census tracts in Los Angeles, California.Methods The study cohort consisted of all self-identified Latinos of primarily Mexican ancestry 40 years and older residing in 6 census tracts in La Puente, California. All participants underwent a complete ophthalmologic examination, including measurement of intraocular pressure (IOP), visual field (VF) testing using an automated field analyzer, and simultaneous stereoscopic fundus photography of the optic disc. Ocular hypertension was defined as IOP of >21 mmHg and the absence of optic disc damage or abnormal VF test results. Open-angle glaucoma was defined as the presence of an open angle and various criteria that included a glaucomatous VF abnormality and/or evidence of glaucomatous optic disc damage in at least one eye.Main outcome measures Prevalence of open-angle glaucoma and ocular hypertension.Results For the 6142 participants who underwent a complete ophthalmologic examination at the clinical center, the prevalence of OAG was 4.74% (95% confidence interval [CI], 4.22%-5.30%). The prevalence of ocular hypertension was 3.56% (95% CI, 3.12%-4.06%). The prevalences of OAG and ocular hypertension were higher in older Latinos than in younger Latinos (P<0.0001). No gender-related differences in prevalences of OAG and ocular hypertension were present. The mean IOP, mean deviation, and mean vertical cup-disc ratio in persons with OAG were 17 mmHg, -9.6 decibels, and 0.6, respectively. Seventy-five percent of Latinos with OAG and 75% of Latinos with ocular hypertension were previously undiagnosed. Further, 17% of Latinos with OAG and 23% of Latinos with ocular hypertension had received treatment for "glaucoma."Conclusion Our data suggest that the prevalence of OAG is high among Latinos of Mexican ancestry. The higher prevalence of OAG in older Latinos emphasizes the public health importance of providing eye care services for the early diagnosis and management of this condition in Latinos.

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Authors
Varma, R., Ying-Lai, M., Francis, B. A., Nguyen, B. B.-T., Deneen, J., Wilson, M. R., & Azen, S. P.
Affiliations
  • University of Southern California (US)
  • Texas Tech University Health Sciences Center (US)
Corresponding author
Varma, Rohit
ORCID
Venue
Ophthalmology
Publisher
Elsevier BV
Published
2004-08
Volume
111
Issue
8
Pages
1439-1448
ISSN
0161-6420 (ISSN-L)
DOI
10.1016/j.ophtha.2004.01.025
OpenAlex
W2105989442
Cited by
483
References
29
Citations by year
2026: 19 · 2025: 23 · 2024: 26 · 2023: 24 · 2022: 31 · 2021: 25 · 2020: 29 · 2019: 20 · 2018: 19 · 2017: 19 · 2016: 22 · 2015: 19 · 2014: 23 · 2013: 29 · 2012: 17
FWCI
15.74
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Ophthalmology (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Eye Institute (P30EY003040, #EY03040, EY11753, U10EY011753)
Topics
  • Health Sciences › Medicine › Ophthalmology › Glaucoma and retinal disorders
  • Health Sciences › Medicine › Epidemiology › Ophthalmology and Visual Impairment Studies
  • Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Corneal surgery and disorders
Keywords
open-angle glaucoma, ocular hypertension, Hispanic Americans, Mexican Americans, prevalence, intraocular pressure, visual field defects, optic disc damage, age differences, undiagnosed glaucoma, glaucoma treatment, eye care, Los Angeles
MeSH terms
Adult, Aged, Aged, 80 and over, Cross-Sectional Studies, Female, Glaucoma, Open-Angle, Hispanic or Latino, Humans, Intraocular Pressure, Functional Laterality, Male, Middle Aged, Ocular Hypertension, Optic Nerve, Optic Nerve Diseases, Visual Fields, Los Angeles, Prevalence, Age Distribution, Sex Distribution

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