Macular thickness as a potential biomarker of mild Alzheimer's disease

Optic-Nerve Degeneration in Alzheimer's Disease

Hinton, D. R., Sadun, A. A., Blanks, J. C., & Miller, C. A. (1986) · New England Journal of Medicine · doi:10.1056/nejm198608213150804 · Cited by 700 · see citing works

Retinal pathology in Alzheimer's disease. I. Ganglion cell loss in foveal/parafoveal retina.

Blanks, J., Torigoe, Y., Hinton, D., & Blanks, R. (1996) · Neurobiology of Aging · doi:10.1016/0197-4580(96)00010-3 · Cited by 351 · see citing works

Alzheimer’s Disease in the Retina: Imaging Retinal Aβ Plaques for Early Diagnosis and Therapy Assessment

Koronyo, Y., Salumbides, B. C., Black, K. L., & Koronyo‐Hamaoui, M. (2012) · Neurodegenerative Diseases · doi:10.1159/000335154 · Cited by 199 · see citing works

Vision function abnormalities in Alzheimer disease

Tzekov, R., & Mullan, M. (2014) · Survey of Ophthalmology · doi:10.1016/j.survophthal.2013.10.002 · Cited by 94 · see citing works

Optical coherence tomography assessed retinal nerve fiber layer thickness in patients with Alzheimer's disease: a meta-analysis.

He, X., Liu, Y., Peng, C., Zhang, F., Zhuang, S., & Zhang, J. (2012) · Europe PMC (PubMed Central) · doi:10.3980/j.issn.2222-3959.2012.03.30 · Cited by 70 · see citing works

The role of microglia in retinal neurodegeneration: Alzheimer’s disease, parkinson, and glaucoma.

Ramirez, A. I., de Hoz, R., Salobrar-Garcia, E., Salazar, J. J., Rojas, B., Ajoy, D., López-Cuenca, I., Rojas, P., Triviño, A., & Ramírez, J. M. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00214 · Cited by 466 · see citing works

Imaging retina to study dementia and stroke

Cheung, C. Y.-L., Ikram, M. K., Chen, C., & Wong, T. Y. (2017) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2017.01.001 · Cited by 276 · see citing works

Association of Retinal Nerve Fiber Layer Thinning With Current and Future Cognitive Decline

Ko, F., Muthy, Z. A., Gallacher, J., Sudlow, C. L. M., Rees, G. E., Yang, Q., Keane, P. A., Petzold, A., Khaw, P. T., Reisman, C. A., et al. (2018) · JAMA Neurology · doi:10.1001/jamaneurol.2018.1578 · Cited by 241 · see citing works

A systematic review and meta‐analysis of retinal nerve fiber layer change in dementia, using optical coherence tomography

Thomson, K. L., Yeo, J. M., Waddell, B., Cameron, J. R., & Pal, S. (2015) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1016/j.dadm.2015.03.001 · Cited by 193 · see citing works

Developing retinal biomarkers for the earliest stages of Alzheimer's disease: What we know, what we don't, and how to move forward

Alber, J., Goldfarb, D., Thompson, L. I., Arthur, E., Hernandez, K., Cheng, D., DeBuc, D. C., Cordeiro, F., Provetti‐Cunha, L., den Haan, J., et al. (2020) · Alzheimer's & Dementia · doi:10.1002/alz.12006 · Cited by 154 · see citing works

Retinal microvascular network alterations: potential biomarkers of cerebrovascular and neural diseases

DeBuc, D. C., Somfai, G. M., & Koller, Á. (2016) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00201.2016 · Cited by 141 · see citing works

Optical Coherence Tomography Reveals Retinal Neuroaxonal Thinning in Frontotemporal Dementia as in Alzheimer’s Disease

Ferrari, L. D., Huang, S., Magnani, G., Ambrosi, A., Comı, G., & Leocani, L. (2017) · Journal of Alzheimer s Disease · doi:10.3233/jad-160886 · Cited by 130 · see citing works

Optical Coherence Tomography as a Biomarker for Diagnosis, Progression, and Prognosis of Neurodegenerative Diseases

Satué, M., Obís, J., Rodrigo, M. J., Otín, S., Fuertes, M. I., Viladés, E., Gracia, H., Ara, J. R., Alarcia, R., Polo, V., et al. (2016) · Journal of Ophthalmology · doi:10.1155/2016/8503859 · Cited by 126 · see citing works

Change in retinal structural anatomy during the preclinical stage of Alzheimer's disease

Santos, C. Y., Johnson, L. N., Sinoff, S. E., Festa, E. K., Heindel, W. C., & Snyder, P. J. (2018) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1016/j.dadm.2018.01.003 · Cited by 124 · see citing works

Changes in visual function and retinal structure in the progression of Alzheimer's disease

Salobrar‐García, E., de Hoz, R., Ramirez, A. I., López‐Cuenca, I., Rojas, P., Vazirani, R., Cuadrado, C. A., Yubero, R., Gil, P., Pinazo-Duran, M. D., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0220535 · Cited by 115 · see citing works

OCT in Alzheimer’s disease: thinning of the RNFL and superior hemiretina

Cunha, J. P., Proença, R. P., Dias‐Santos, A., de Almeida, R. M., Águas, H., Alves, M., Papoila, A. L., Louro, C., & Castanheira-Dinis, A. (2017) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-017-3715-9 · Cited by 109 · see citing works

Alzheimer's disease pathophysiology in the Retina

Gaire, B. P., Koronyo, Y., Fuchs, D.-T. S., Shi, H., Rentsendorj, A., Danziger, R., Vit, J., Mirzaei, N., Doustar, J., Sheyn, J., et al. (2024) · Progress in Retinal and Eye Research · doi:10.1016/j.preteyeres.2024.101273 · Cited by 102 · see citing works

Optical coherence tomography angiography as a potential screening tool for cerebral small vessel diseases

Lee, J., Kim, J. P., Jang, H., Kim, J., Kang, S. H., Kim, J. S., Lee, J. M., Jung, Y. H., Na, D. L., Seo, S. W., et al. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-020-00638-x · Cited by 98 · see citing works

Macular Ganglion Cell -Inner Plexiform Layer Thickness Is Associated with Clinical Progression in Mild Cognitive Impairment and Alzheimers Disease

Choi, S. H., Park, S. J., & Kim, N. R. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162202 · Cited by 95 · see citing works

Motoric cognitive risk syndrome: Integration of two early harbingers of dementia in older adults

Semba, R. D., Tian, Q., Carlson, M. C., Xue, Q., & Ferrucci, L. (2020) · Ageing Research Reviews · doi:10.1016/j.arr.2020.101022 · Cited by 88 · see citing works

Visual dysfunction and its correlation with retinal changes in patients with Alzheimer's disease

Polo, V., Rodrigo, M. J., García‐Martín, E., Otín, S., Poves, J. M. L., FUERTES, M., BAMBO, M., Pablo, L. E., & Satué, M. (2017) · Eye · doi:10.1038/eye.2017.23 · Cited by 86 · see citing works

Optical Coherence Tomography in the UK Biobank Study – Rapid Automated Analysis of Retinal Thickness for Large Population-Based Studies

Keane, P. A., Grossi, C. M., Foster, P. J., Yang, Q., Reisman, C. A., Chan, K., Pető, T., Thomas, D., & Patel, P. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164095 · Cited by 84 · see citing works

Eye-tracking paradigms for the assessment of mild cognitive impairment: a systematic review

Wolf, A., Tripanpitak, K., Umeda, S., & Otake, M. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1197567 · Cited by 86 · see citing works

Neurodegeneration in Alzheimer’s disease and glaucoma: overlaps and missing links

Sen, S., Saxena, R., Tripathi, M., Vibha, D., & Dhiman, R. (2020) · Eye · doi:10.1038/s41433-020-0836-x · Cited by 79 · see citing works

Combination of snapshot hyperspectral retinal imaging and optical coherence tomography to identify Alzheimer’s disease patients

Lemmens, S., Craenendonck, T. V., Eijgen, J. V., Groef, L. D., Bruffaerts, R., Jesus, D. A. D., Charle, W., Jayapala, M., Sunaric‐Mégevand, G., Standaert, A., et al. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-020-00715-1 · Cited by 78 · see citing works

Analysis of Retinal Peripapillary Segmentation in Early Alzheimer’s Disease Patients

Salobrar‐García, E., Hoyas, I., Leal, M., de Hoz, R., Rojas, B., Ramirez, A. I., Salazar, J. J., Yubero, R., Gil, P., Triviño, A., et al. (2015) · BioMed Research International · doi:10.1155/2015/636548 · Cited by 76 · see citing works

Actin-mediated Microglial Chemotaxis via G-Protein Coupled Purinergic Receptor in Alzheimer’s Disease

Das, R. R., & Chinnathambi, S. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.09.024 · Cited by 71 · see citing works

Visual system manifestations of Alzheimer's disease

Kusne, Y. N., Wolf, A. B., Townley, K., Conway, M. D., & Peyman, G. A. (2016) · Acta Ophthalmologica · doi:10.1111/aos.13319 · Cited by 69 · see citing works

Potential Utility of Retinal Imaging for Alzheimer’s Disease: A Review

Liao, H., Zhu, Z., & Peng, Y. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00188 · Cited by 69 · see citing works

Usefulness of peripapillary nerve fiber layer thickness assessed by optical coherence tomography as a biomarker for Alzheimer’s disease

Sánchez, D., Castilla-Marti, M., Rodríguez‐Gómez, O., Valero, S., Piferrer, A., Martínez, G., Martínez, J., Serra, J., Moreno–Grau, S., Hernández‐Olasagarre, B., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-34577-3 · Cited by 63 · see citing works

The role of optical coherence tomography in Alzheimer’s disease

Cunha, L. P., Almeida, A. L. M., Costa-Cunha, L. V. F., Costa, C. F., & Monteiro, M. L. R. (2016) · International Journal of Retina and Vitreous · doi:10.1186/s40942-016-0049-4 · Cited by 57 · see citing works

Relationships between retinal layer thickness and brain volumes in the UK Biobank cohort

Chua, S. Y. L., Lascaratos, G., Atan, D., Zhang, B., Reisman, C. A., Khaw, P. T., Smith, S. M., Matthews, P. M., Petzold, A., Strouthidis, N. G., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14706 · Cited by 54 · see citing works

Optical Coherence Tomography in Patients with Alzheimer’s Disease: What Can It Tell Us?

Song, A., Johnson, N., Ayala, A. M., & Thompson, A. C. (2021) · Eye and Brain · doi:10.2147/eb.s235238 · Cited by 50 · see citing works

Spatial analysis of thickness changes in ten retinal layers of Alzheimer’s disease patients based on optical coherence tomography

Jáñez‐Escalada, L., Jáñez-García, L., Salobrar‐García, E., Santos‐Mayo, A., de Hoz, R., Yubero, R., Gil, P., & Ramirez, J. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-49353-0 · Cited by 47 · see citing works

Identification of Retinal Biomarkers in Alzheimer’s Disease Using Optical Coherence Tomography: Recent Insights, Challenges, and Opportunities

DeBuc, D. C., Gaca-Wysocka, M., Grzybowski, A. E., & Kanclerz, P. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8070996 · Cited by 45 · see citing works

Inherited Photoreceptor Degeneration Causes the Death of Melanopsin-Positive Retinal Ganglion Cells and Increases Their Coexpression of Brn3a

García‐Ayuso, D., Pierdomenico, J. D., Esquiva, G., Nadal-Nicolás, F. M., Pinilla, I., Cuenca, N., Vidal‐Sanz, M., Agudo‐Barriuso, M., & Villegas‐Pérez, M. P. (2015) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.15-16808 · Cited by 46 · see citing works

Can the retina be used to diagnose and plot the progression of Alzheimer's disease?

Mahajan, D., & Votruba, M. (2017) · Acta Ophthalmologica · doi:10.1111/aos.13472 · Cited by 41 · see citing works

Changes in Retinal OCT and Their Correlations with Neurological Disability in Early ALS Patients, a Follow-Up Study

Rojas, P., de Hoz, R., Ramirez, A. I., Ferreras, A., Salobrar‐García, E., Muñoz-Blanco, J. L., Urcelay-Segura, J. L., Salazar, J. J., & Ramirez, J. M. (2019) · Brain Sciences · doi:10.3390/brainsci9120337 · Cited by 40 · see citing works

Association of Cognitive Function with Amyloid-β and Tau Proteins in the Vitreous Humor

Wright, L. M., Stein, T. D., Jun, G., Chung, J., McConnell, K. H., Fiorello, M. G., Siegel, N. H., Ness, S. D., Xia, W., Turner, K. L., et al. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-181104 · Cited by 39 · see citing works

Macular Thickness Decrease in Asymptomatic Subjects at High Genetic Risk of Developing Alzheimer’s Disease: An OCT Study

López‐Cuenca, I., de Hoz, R., Salobrar‐García, E., Elvira‐Hurtado, L., Rojas, P., Fernández‐Albarral, J. A., Barabash, A., Salazar, J. J., Ramirez, A. I., & Ramirez, J. M. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9061728 · Cited by 37 · see citing works

Retinal Dysfunction in Alzheimer’s Disease and Implications for Biomarkers

Liao, C., Xu, J., Chen, Y., & Ip, N. Y. (2021) · Biomolecules · doi:10.3390/biom11081215 · Cited by 36 · see citing works

Alzheimer’s disease: A review of its visual system neuropathology. Optical coherence tomography—a potential role as a study tool in vivo

Cunha, J. P., Moura‐Coelho, N., Proença, R. P., Dias‐Santos, A., Ferreira, J., Louro, C., & Castanheira-Dinis, A. (2016) · Graefe s Archive for Clinical and Experimental Ophthalmology · doi:10.1007/s00417-016-3430-y · Cited by 35 · see citing works

Retinal imaging biomarkers of Alzheimer's disease: A systematic review and meta‐analysis of studies using brain amyloid beta status for case definition

Ashraf, G., McGuinness, M. B., Khan, M. A., Obtinalla, C., Hadoux, X., & van Wijngaarden, P. (2023) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12421 · Cited by 38 · see citing works

The Value of OCT and OCTA as Potential Biomarkers for Preclinical Alzheimer’s Disease: A Review Study

López‐Cuenca, I., Salobrar‐García, E., Elvira‐Hurtado, L., Fernández‐Albarral, J. A., Sánchez-Puebla, L., Salazar, J. J., Ramirez, J. M., Ramirez, A. I., & de Hoz, R. (2021) · Life · doi:10.3390/life11070712 · Cited by 33 · see citing works

The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer’s disease: an exploratory analysis

López‐Cuenca, I., Dolado, A. M., Yus, M., Salobrar‐García, E., Elvira‐Hurtado, L., Fernández‐Albarral, J. A., Salazar, J. J., Ramirez, A. I., Sánchez-Puebla, L., Fuentes, M. E., et al. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-01008-5 · Cited by 31 · see citing works

Retinal Thickness Changes Over Time in a Murine AD Model APPNL-F/NL-F

Salobrar‐García, E., López‐Cuenca, I., Sánchez-Puebla, L., de Hoz, R., Fernández‐Albarral, J. A., Ramirez, A. I., Bravo‐Ferrer, I., Medina, V., Moro, M. Á., Saido, T. C., et al. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2020.625642 · Cited by 29 · see citing works

A Systematic Review on Retinal Biomarkers to Diagnose Dementia from OCT/OCTA Images

Ibrahim, Y., Xie, J., Macerollo, A., Sardone, R., Shen, Y., Romano, V., & Zheng, Y. (2023) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-230042 · Cited by 28 · see citing works

Ophthalmologic Psychophysical Tests Support OCT Findings in Mild Alzheimer’s Disease

Salobrar‐García, E., de Hoz, R., Rojas, B., Ramirez, A. I., Salazar, J. J., Yubero, R., Gil, P., Triviño, A., & Ramirez, J. M. (2015) · Journal of Ophthalmology · doi:10.1155/2015/736949 · Cited by 28 · see citing works

Peripapillary Retinal Nerve Fiber Layer Thickness and the Evolution of Cognitive Performance in an Elderly Population

Méndez-Gómez, J. L., Rougier, M., Tellouck, L., Korobelnik, J., Schweitzer, C., Delyfer, M., Amieva, H., Dartigues, J., Delcourt, C., & Helmer, C. (2017) · Frontiers in Neurology · doi:10.3389/fneur.2017.00093 · Cited by 28 · see citing works

Neuro-Retina Might Reflect Alzheimer’s Disease Stage

Santangelo, R., Huang, S., Bernasconi, M. P., Falautano, M., Comı, G., Magnani, G., & Leocani, L. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-200043 · Cited by 26 · see citing works

Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-020-00677-4 · Cited by 25 · see citing works

Quantitative assessment of retinal thickness and vessel density using optical coherence tomography angiography in patients with Alzheimer’s disease and glaucoma

Zabel, P., Kałuzny, J. J., Zabel, K., Kaluzna, M., Lamkowski, A., Jaworski, D., Makowski, J., Gębska‐Tołoczko, M., & Kucharski, R. (2021) · PLoS ONE · doi:10.1371/journal.pone.0248284 · Cited by 25 · see citing works

Ocular biomarkers and their role in the early diagnosis of neurocognitive disorders

Chalkias, I.-N., Tegos, T. J., Topouzis, F., & Tsolaki, M. (2021) · European Journal of Ophthalmology · doi:10.1177/11206721211016311 · Cited by 24 · see citing works

A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease

Chua, J., Li, C., Ho, L. K. H., Wong, D. W. K., Tan, B., Yao, X., Gan, A. T. L., Schwarzhans, F., Garhöfer, G., Sng, C. C. A., et al. (2022) · Alzheimer s Research & Therapy · doi:10.1186/s13195-022-00982-0 · Cited by 24 · see citing works

Detection of structural and electrical disturbances in macula and optic nerve in Alzheimer’s patients and their correlation with disease severity

Sen, S., Saxena, R., Vibha, D., Tripathi, M., Sharma, P. K., Phuljhele, S., Tandon, R., & Kumar, P. (2020) · Seminars in Ophthalmology · doi:10.1080/08820538.2020.1748203 · Cited by 24 · see citing works

Neurodegenerative biomarkers in different chambers of the eye relative to plasma: an agreement validation study

Sampani, K., Ness, S. D., Tuz‐Zahra, F., Aytan, N., Spurlock, E., Alluri, S., Chen, X., Siegel, N. H., Alosco, M. L., Xia, W., et al. (2024) · Alzheimer s Research & Therapy · doi:10.1186/s13195-024-01556-y · Cited by 23 · see citing works

Myeloid cells in retinal and brain degeneration

Guo, M., Schwartz, T. D., Dunaief, J. L., & Cui, Q. N. (2021) · FEBS Journal · doi:10.1111/febs.16177 · Cited by 24 · see citing works

Protein and Imaging Biomarkers in the Eye for Early Detection of Alzheimer’s Disease

Fereshetian, S., Agranat, J. S., Siegel, N. H., Ness, S. D., Stein, T. D., & Subramanian, M. L. (2021) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-210283 · Cited by 21 · see citing works

Using Retinal Imaging to Study Dementia

Chan, V. T. T., Tso, T., Tang, F., Tham, C. C. Y., Mok, V., Chen, C., Wong, T. Y., & Cheung, C. Y.-L. (2017) · Journal of Visualized Experiments · doi:10.3791/56137 · Cited by 20 · see citing works

Correlation between retinal nerve fibre layer thickness and white matter lesions in Alzheimer's disease

Barrios, L. C., Archidona‐Arranz, A., Ruiz, J. A. C., García‐Basterra, I., Garzón-Maldonado, F. J., Castro, V. S., Gutiérrez‐Bedmar, M., Barbancho, M. Á., Cosme, C. D. L. C., García-Campos, J. M., et al. (2021) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.5496 · Cited by 19 · see citing works

A recommended “minimum data set” framework for SD‐OCT retinal image acquisition and analysis from the Atlas of Retinal Imaging in Alzheimer's Study (ARIAS)

Alber, J., Arthur, E., Sinoff, S. E., DeBuc, D. C., Chew, E. Y., Douquette, L., Hatch, W. V., Hudson, C., Kashani, A. H., Lee, C. S., et al. (2020) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.12119 · Cited by 19 · see citing works

A systematic survey of advances in retinal imaging modalities for Alzheimer’s disease diagnosis

Vij, R., & Arora, S. (2022) · Metabolic Brain Disease · doi:10.1007/s11011-022-00927-4 · Cited by 19 · see citing works

Meta-analysis of the relationship of peripheral retinal nerve fiber layer thickness to Alzheimer's disease and mild cognitive impairment.

Wang, M., Zhu, Y., Shi, Z., Li, C., & Shen, Y. (2015) · PubMed Central · doi:10.11919/j.issn.1002-0829.215100 · Cited by 19 · see citing works

A multi-regression approach to improve optical coherence tomography diagnostic accuracy in multiple sclerosis patients without previous optic neuritis

Chua, J., Bostan, M., Li, C., Sim, Y. C., Bujor, I. A., Wong, D. W. K., Tan, B., Yao, X., Schwarzhans, F., Garhöfer, G., et al. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103010 · Cited by 16 · see citing works

Retinal Optical Coherence Tomography in Neurodegenerative Diseases (Review)

Svetozarskiy, S. N., & Kopishinskaya, S. V. (2015) · Современные технологии в медицине · doi:10.17691/stm2015.7.1.14 · Cited by 16 · see citing works

A window to beyond the orbit: the value of optical coherence tomography in non‐ocular disease

Cameron, J. R., & Tatham, A. J. (2016) · Acta Ophthalmologica · doi:10.1111/aos.12978 · Cited by 14 · see citing works

OCT Imaging in Murine Models of Alzheimer’s Disease in a Systematic Review: Findings, Methodology and Future Perspectives

Sánchez-Puebla, L., López‐Cuenca, I., Salobrar‐García, E., Ramirez, A. I., Fernández‐Albarral, J. A., Matamoros, J. A., Elvira‐Hurtado, L., Salazar, J. J., Ramirez, J. M., & de Hoz, R. (2024) · Biomedicines · doi:10.3390/biomedicines12030528 · Cited by 14 · see citing works

Retinal and Choroidal Changes in Men Compared with Women with Alzheimer’s Disease

Mirzania, D., Thompson, A., Robbins, C. B., Soundararajan, S., Lee, J., Agrawal, R. V., Liu, A. J., Johnson, K. G., Grewal, D., & Fekrat, S. (2021) · Ophthalmology Science · doi:10.1016/j.xops.2021.100098 · Cited by 9 · see citing works

Macular Thickness in Subjective Memory Complaints and Mild Cognitive Impairment: A Non-Invasive Biomarker

Castejón, D. G., Dudekova, M., Gallego, M. G., & Lajara, J. (2016) · Neuro-Ophthalmology · doi:10.3109/01658107.2015.1118516 · Cited by 11 · see citing works

Evaluation of the visual system with visual evoked potential and optical coherence tomography in patients with idiopathic Parkinson's disease and with multiple system atrophy

Batum, M., Ak, A. K., Arı, S., Mayalı, H., Kurt, E., & Selçuki, D. (2022) · Documenta Ophthalmologica · doi:10.1007/s10633-022-09887-7 · Cited by 11 · see citing works

Retinal thickness and vascular parameters using optical coherence tomography in Alzheimer’s disease: a meta-analysis

Sheriff, S., Shen, T., Abdal, S., Saks, D., Mirzaei, M., Gupta, V. B., Chitranshi, N., You, Y., Schultz, A., Graham, S. L., et al. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.371380 · Cited by 10 · see citing works

Retinal Ganglion Cell Complex in Alzheimer Disease: Comparing Ganglion Cell Complex and Central Macular Thickness in Alzheimer Disease and Healthy Subjects Using Spectral Domain-Optical Coherence Tomography

Farzinvash, Z., abutorabi-zarchi, M., Manaviat, M. R., & Mehrjardi, H. Z. (2021) · Basic and Clinical Neuroscience Journal · doi:10.32598/bcn.2021.2040.1 · Cited by 10 · see citing works

Changes in Ocular Biomarkers from Normal Cognitive Aging to Alzheimer’s Disease: A Pilot Study

Chaitanuwong, P., Jariyakosol, S., Apinyawasisuk, S., Hirunwiwatkul, P., Lawanlattanagul, H., Hemrungrojn, S., & Chongpison, Y. (2023) · Eye and Brain · doi:10.2147/eb.s391608 · Cited by 10 · see citing works

Retinal Microstructural and Microvascular Changes in Alzheimer Disease: A Review

Ordoñez, M. A. O., Smith, R. C., Yiu, G. C., & Liu, Y. (2024) · International Ophthalmology Clinics · doi:10.1097/iio.0000000000000549 · Cited by 9 · see citing works

Retinale Bildgebung von Makula und Papille bei neurodegenerativen Erkrankungen

Turski, G. N., Schmitz-Valckenberg, S., Holz, F. G., & Finger, R. P. (2016) · Der Ophthalmologe · doi:10.1007/s00347-016-0412-8 · Cited by 9 · see citing works

The Impact of the Eye in Dementia: The Eye and its Role in Diagnosis and Follow‐up

Salobrar‐García, E., Ramirez, A. I., de Hoz, R., Rojas, P., Salazar, J. J., Rojas, B., Yubero, R., Gil, P., Triviño, A., & Ramirez, J. M. (2016) · InTech eBooks · doi:10.5772/64490 · Cited by 8 · see citing works

Association between cognitive performance and self-reported glaucoma in middle-aged and older adults: a cross-sectional analysis of ELSA-Brasil

Vidal, K. M., Suemoto, C., Moreno, A., Duncan, B. B., Schmidt, M. I., Maestri, M., Barreto, S. M., Lotufo, P., Bertola, L., Benseñor, I., et al. (2020) · Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · doi:10.1590/1414-431x202010347 · Cited by 7 · see citing works

Use of artificial intelligence algorithms to predict systemic diseases from retinal images

Khan, R., Surya, J., Roy, M., Priya, M. N. S., Mohan, S., Raman, S., Raman, A., Vyas, A., & Raman, R. (2023) · Wiley Interdisciplinary Reviews Data Mining and Knowledge Discovery · doi:10.1002/widm.1506 · Cited by 7 · see citing works

Alzheimer’s disease: a continuum with visual involvements

Elvira‐Hurtado, L., López‐Cuenca, I., de Hoz, R., Salas, M., Sánchez-Puebla, L., Ramírez‐Toraño, F., Matamoros, J. A., Fernández‐Albarral, J. A., Rojas, P., Alfonsín, S., et al. (2023) · Frontiers in Psychology · doi:10.3389/fpsyg.2023.1124830 · Cited by 7 · see citing works

Microglial Hemoxygenase-1 Deletion Reduces Inflammation in the Retina of Old Mice with Tauopathy

Fernández‐Albarral, J. A., Salobrar‐García, E., Matamoros, J. A., Fernández‐Mendívil, C., del Sastre, E., Chen, L., de Hoz, R., López‐Cuenca, I., Sánchez-Puebla, L., Ramirez, J. M., et al. (2022) · Antioxidants · doi:10.3390/antiox11112151 · Cited by 4 · see citing works

Ocular Exploration in the Diagnosis and Follow-Up of the Alzheimer’s Dementia

Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, U. C. D. M., Salobrar‐García, E., de Hoz, R., Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, U. C. D. M., Facultad de Óptica y Optometría, U. C. D. M., Ramirez, A. I., Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, U. C. D. M., Facultad de Óptica y Optometría, U. C. D. M., Salazar, J. J., Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, U. C. D. M., et al. (2019) · Codon Publications eBooks · doi:10.15586/alzheimersdisease.2019.ch10 · Cited by 4 · see citing works

Visual disorders and driving ability in persons with dementia: A mini review

Papageorgiou, E., Tsirelis, D., Lazari, K., Siokas, V., Dardiotis, E., & Tsironi, E. E. (2022) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2022.932820 · Cited by 3 · see citing works

Ophthalmic examination in the debut and during progression of neurodegenerative diseases

Фурсова, А. Ж., Gamza, Y. A., Zubkova, M. Y., Derbeneva, A. S., Doronina, O. B., Doronina, K. S., Bulatova, N. V., & Belgibaeva, A. S. (2021) · Russian Ophthalmological Journal · doi:10.21516/2072-0076-2021-14-1-104-110 · Cited by 3 · see citing works

Glial fibrillary acidic protein, an early and sustained indicator of retinopathy progression

Fernández, Y., Subirada, P. V., Vaglienti, M. V., Tovo, A., Paz, M. C., Barcelona, P. F., & Sanchez, M. C. (2025) · Experimental Eye Research · doi:10.1016/j.exer.2025.110796 · Cited by 2 · see citing works

Application of Structural Retinal Biomarkers to Detect Cognitive Impairment in a Primary Care Setting

Mozdbar, S., Petersen, M. E., Zhang, F., Johnson, L. A., Tolman, A., Nyalakonda, R., Gutierrez, A., & O’Bryant, S. E. (2022) · Journal of Alzheimer s Disease Reports · doi:10.3233/adr-220070 · Cited by 2 · see citing works

Exploratory Longitudinal Study of Ocular Structural and Visual Functional Changes in Subjects at High Genetic Risk of Developing Alzheimer’s Disease

López‐Cuenca, I., Sánchez-Puebla, L., Salobrar‐García, E., Álvarez-Gutierrez, M., Elvira‐Hurtado, L., Barabash, A., Ramírez‐Toraño, F., Fernández‐Albarral, J. A., Matamoros, J. A., Nebreda, A., et al. (2023) · Biomedicines · doi:10.3390/biomedicines11072024 · Cited by 2 · see citing works

Inner and outer retinal abnormalities detected in Alzheimer's disease subjects diagnosed by amyloid PET not revealed when classified based on clinical criteria

Ariello, L. E., Faria, D. D. P., Andrade, T. D. S., Oyamada, M. K., Cunha, L. P., Westenhofen, G. K., Nasser, R. V., Yokomizo, J. E., Duran, F., Porto, F. H. D. G., et al. (2025) · Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring · doi:10.1002/dad2.70218 · Cited by 1 · see citing works

Оптическая к Огерентная тОмОграфия сетчатки при нейрОдегенеративных забОлеваниях

Svetozarskiy, S. N., Resident, C., Square, P., Novgorod, N., & Russian Federation (2015) · CyberLeninK (CyberLeninka)

Trans Neuronal Retrograde Degeneration to OCT in Central Nervous System Diseases

Sánchez-Dalmau, B. F., Torres–Torres, R., Keller, J., Martínez‐Lapiscina, E. H., & Villoslada, P. (2016) · Springer eBooks · doi:10.1007/978-3-319-24085-5_11

Cardiovascular and Retinal Vascular Changes in Preclinical Alzheimer's Disease

Santos, C. (2018) · doi:10.23860/diss-santos-claudia-2018

RETINAL NEURODEGENERATION IN PATIENTS WITH MILD COGNITIVE IMPAIRMENT AND ALZHEIMER S DISEASE AN OPTICAL COHERENCE TOMOGRAPHY STUDY

ÖLÇÜCÜOĞLU, L. C. A. (2021) · The Turkish Journal of Geriatrics · doi:10.31086/tjgeri.2021.214

Trans Neuronal Retrograde Degeneration to OCT in Central Nervous System Diseases

Sánchez-Dalmau, B. F., Camós‐Carreras, A., Torres–Torres, R., Keller, J., Sánchez-Vela, L., Martínez‐Lapiscina, E. H., & Villoslada, P. (2020) · Springer eBooks · doi:10.1007/978-3-030-26269-3_17

Prediction of Disease Using Retinal Image in Deep Learning

Sivakani, R., & Masood, M. (2023) · Lecture notes in electrical engineering · doi:10.1007/978-981-19-7753-4_25

Trans-synaptic Retrograde Degeneration in the Visual Pathway in Central Nervous System Diseases

Sánchez-Dalmau, B. F., Brotons-Muñoz, E., Camós‐Carreras, A., Alcubierre, R., & Villoslada, P. (2025) · Springer eBooks · doi:10.1007/978-3-031-72156-4_17

Additional file 2 of Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12972148

Additional file 4 of Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12972154

Additional file 1 of The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer’s disease: an exploratory analysis

López-Cuenca, I., Marcos-Dolado, A., Yus, M., Salobrar‐García, E., Elvira‐Hurtado, L., Albarral, J. A. F., Salazar, J. J., Ramírez, A. I., Sánchez-Puebla, L., Fuentes-Ferrer, M. E., et al. (2022) · Figshare · doi:10.6084/m9.figshare.20004602

Additional file 1 of Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12972145

Additional file 5 of Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12972157

Additional file 3 of Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12972151

Additional file 6 of Neurofilament light chain in the vitreous humor of the eye

Subramanian, M. L., Vig, V., Chung, J., Fiorello, M. G., Xia, W., Zetterberg, H., Blennow, K., Zetterberg, M., Shareef, F., Siegel, N. H., et al. (2020) · Figshare · doi:10.6084/m9.figshare.12972160

Biomarqueurs rétiniens de la maladie d'Alzheimer et du vieillissement cérébral

Gomez, J. L. M. (2016) · doi:10.70675/477e6a1ez209az4a71za0c6z8629c2d7e785

Brain care score and retinal health: structural and metabolic insights from the UK Biobank

Yu, J., Zhang, Y., Gao, Y. L., Ho, M., Kam, K. W., Gong, B., Young, A. L., Pang, C. P., Tham, C. C., Yam, J. C. S., et al. (2026) · GeroScience · doi:10.1007/s11357-026-02579-z

Detection of retinal nerve fiber layer degeneration in patients with Alzheimer's disease using optical coherence tomography: searching new biomarkers

BAMBO, M., García‐Martín, E., Pinilla, J., Herrero, R., Satué, M., Otín, S., Fuertes, I., Marques, M. L., & Pablo, L. E. (2014) · Acta Ophthalmologica · doi:10.1111/aos.12374 · Cited by 48 · see citing works

ALZHEIMER'S DISEASE: EARLY NEURODEGENERATION INDICATORS IN THE RETINA -A NARRATIVE REVIEW

Gupta, S., & Abbas, M. (2026) · EPRA International Journal of Multidisciplinary Research (IJMR) · doi:10.36713/epra27802

P2‐166: Retinal Thickness in Alzheimer′s Disease: A Potential Diagnostic Biomarker? Evidence from an Amyloid Proven Early Onset Alzheimer′s Disease Cohort

den Haan, J., Janssen, S. F., van Berckel, B. N. M., Teunissen, C. E., Verbraak, F. D., & Bouwman, F. H. (2016) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2016.06.1333 · Cited by 1 · see citing works

Retinal Nerve Fiber Layer Measurement in Patients with Alzheimer’s Disease

Kasl, Z., Rušňák, Š., & Jirásková, N. (2016) · Česká a slovenská neurologie a neurochirurgie · doi:10.14735/amcsnn2016424 · Cited by 1 · see citing works

Retinal biomarkers in Alzheimer’s disease and mild cognitive impairment: A systematic review and meta-analysis

Ge, Y., Xu, W., Ou, Y., Qu, Y., Ma, Y., Huang, Y., Shen, X., Chen, S.-D., Tan, L., Zhao, Q., et al. (2021) · Ageing Research Reviews · doi:10.1016/j.arr.2021.101361 · Cited by 116 · see citing works