CoChat
Sign Up
Cited by 536Musculoskeletal pain and rehabilitationPain Mechanisms and TreatmentsNeural and Behavioral Psychology Studies

The DOI matches its Crossref record; 37 of the 37 references it cites were found in a registry or an index.

Chronic pain patients are impaired on an emotional decision-making task

Apkarian, Vania A., Sosa, Yamaya, Krauss, Beth R., Thomas, Sebastian P., Fredrickson, Bruce E., Levy, Robert E., Harden, Norman R., Chialvo, Dante R.·2004·Pain
DOI 10.1016/j.pain.2003.12.015
Open this paper in CoChat — free account

Abstract

Chronic pain can result in anxiety, depression and reduced quality of life. However, its effects on cognitive abilities have remained unclear although many studies attempted to psychologically profile chronic pain. We hypothesized that performance on an emotional decision-making task may be impaired in chronic pain since human brain imaging studies show that brain regions critical for this ability are also involved in chronic pain. Chronic back pain (CBP) patients, chronic complex regional pain syndrome (CRPS) patients, and normal volunteers (matched for age, sex, and education) were studied on the Iowa Gambling Task, a card game developed to study emotional decision-making. Outcomes on the gambling task were contrasted to performance on other cognitive tasks. The net number of choices made from advantageous decks after subtracting choices made from disadvantageous decks on average was 22.6 in normal subjects (n = 26), 13.4 in CBP patients (n = 26), and -9.5 in CRPS patients (n = 12), indicating poor performance in the patient groups as compared to the normal controls (P < 0.004). Only pain intensity assessed during the gambling task was correlated with task outcome and only in CBP patients (r = -0.75, P < 0.003). Other cognitive abilities, such as attention, short-term memory, and general intelligence tested normal in the chronic pain patients. Our evidence indicates that chronic pain is associated with a specific cognitive deficit, which may impact everyday behavior especially in risky, emotionally laden, situations.

Overview

Integrity signals

Registry

Crossref · 10.1016/j.pain.2003.12.015

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Cited by

Sorted by citations

See all 536

Related

See all

Metadata

Authors
Apkarian, V. A., Sosa, Y., Krauss, B. R., Thomas, S. P., Fredrickson, B. E., Levy, R. E., Harden, N. R., & Chialvo, D. R.
Affiliations
  • Northwestern University (US)
  • SUNY Upstate Medical University (US)
ORCID
Chialvo, Dante R.
Venue
Pain
Publisher
Ovid Technologies (Wolters Kluwer Health)
Published
2004-03
Volume
108
Issue
1
Pages
129-136
ISSN
0304-3959 (ISSN-L)
DOI
10.1016/j.pain.2003.12.015
OpenAlex
W2144854156
Cited by
536
References
37
Citations by year
2026: 14 · 2025: 23 · 2024: 21 · 2023: 21 · 2022: 15 · 2021: 31 · 2020: 24 · 2019: 18 · 2018: 32 · 2017: 31 · 2016: 24 · 2015: 28 · 2014: 44 · 2013: 35 · 2012: 31
FWCI
9.21
Type
journal article
Language
en
Open access
closed
Locations
  • Pain (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Institute of Neurological Disorders and Stroke (NS35115, R01NS035115)
Topics
  • Health Sciences › Health Professions › Physical Therapy, Sports Therapy and Rehabilitation › Musculoskeletal pain and rehabilitation
  • Health Sciences › Medicine › Physiology (medical) › Pain Mechanisms and Treatments
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
Keywords
chronic pain, emotional decision-making, Iowa Gambling Task, chronic back pain, complex regional pain syndrome, cognitive impairment, pain intensity, risk assessment
MeSH terms
Adult, Back Pain, Chronic Disease, Cognition, Decision Making, Emotions, Female, Humans, Male, Middle Aged, Neuropsychological Tests, Complex Regional Pain Syndromes

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review