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Cited by 265

The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.

Prevalence of chronic pain seven years following limb threatening lower extremity trauma ☆

Castillo, Renan C., MacKenzie, Ellen J., Wegener, Stephen T., Bosse, Michael J.·2006·Pain

Abstract

Although the etiology of chronic pain following trauma is not well understood, numerous retrospective studies have shown that a significant proportion of chronic pain patients have a history of traumatic injury. The present analysis examines the prevalence and early predictors of chronic pain in a cohort of prospectively followed severe lower extremity trauma patients. Chronic pain was measured using the Graded Chronic Pain Scale, which measures both pain severity and pain interference with activities. Severe lower extremity trauma patients report significantly higher levels of chronic pain than the general population (p<0.001). Their levels are comparable to primary care migraine headache and back pain populations. A number of early predictors of chronic pain were identified, including: having less than a high school education (p<0.01), having less than a college education (p<0.001), low self-efficacy for return to usual major activities (p<0.01), and high levels of average alcohol consumption at baseline (p<0.05). In addition, high reported pain intensity, high levels of sleep and rest dysfunction, and elevated levels of depression and anxiety at 3 months post-discharge were also strong predictors of chronic pain at seven years (p<0.001 for all three predictors). After adjusting for early pain intensity, patients treated with narcotic medication during the first 3 months post-discharge had lower levels of chronic pain at 84 months. It is possible that for patients within these high risk categories, early referral to pain management and/or psychologic intervention may reduce the likelihood or severity of chronic pain.

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Metadata

Authors
Castillo, R. C., MacKenzie, E. J., Wegener, S. T., & Bosse, M. J.
Venue
Pain
Published
2006-10
Volume
124
Issue
3
Pages
321-329
ISSN
0304-3959 (ISSN-L)
OpenAlex
W2070820116
Cited by
265
References
12
FWCI
4.72
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Prevalence of chronic pain seven years following limb threatening lower extremity trauma ☆. https://app.cochat.ai/papers/10.1016/j.pain.2006.04.020
The paper
Castillo, R. C., MacKenzie, E. J., Wegener, S. T., & Bosse, M. J. (2006). Prevalence of chronic pain seven years following limb threatening lower extremity trauma ☆. Pain. https://doi.org/10.1016/j.pain.2006.04.020

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.