How do sleep disturbance and chronic pain inter-relate? Insights from the longitudinal and cognitive-behavioral clinical trials literature

Smith, Michael T; Haythornthwaite, Jennifer A

doi:10.1016/s1087-0792(03)00044-3

Cited by 914Sleep and related disordersMusculoskeletal pain and rehabilitationObstructive Sleep Apnea Research

How do sleep disturbance and chronic pain inter-relate? Insights from the longitudinal and cognitive-behavioral clinical trials literature

Smith, Michael T, Haythornthwaite, Jennifer A·2004·Sleep Medicine Reviews

DOI 10.1016/s1087-0792(03)00044-3

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Abstract

Sleep disturbance is perhaps one of the most prevalent complaints of patients with chronically painful conditions. Experimental studies of healthy subjects and cross-sectional research in clinical populations suggest the possibility that the relationship between sleep disturbance and pain might be reciprocal, such that pain disturbs sleep continuity/quality and poor sleep further exacerbates pain. This suggests that aggressive management of sleep disturbance may be an important treatment objective with possible benefits beyond the improvement in sleep. Little is known, however, about how to effectively treat sleep disturbance associated with pain or whether such treatment might have beneficial effects on reducing pain. A small, but growing literature has applied cognitive-behavioral therapies (CBT) for either pain management or insomnia to patients with chronic pain. In this article, we review the longitudinal literature on sleep disturbance associated with chronic pain and clinical trial literatures of cognitive-behavior therapy for pain management and insomnia secondary to chronic pain with the aim of evaluating whether the relationship between clinical pain and insomnia is reciprocal. While methodological problems are common, the literature suggests that the relationship is reciprocal and CBT treatments for pain or insomnia hold promise in reducing pain severity and improving sleep quality. Directions for future research include the use of validated measures of sleep, longitudinal studies, and larger randomized clinical trials incorporating appropriate attentional controls and longer periods of follow-up.

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Dysfunction in the physiology of sleep is common in those suffering from chronic pain.
“Dysfunction in the physiology of sleep is common in those suffering from chronic pain (Smith and Haythornthwaite, 2004).”
From Self-management strategies to consider to combat endometriosis symptoms during the COVID-19 pandemic (2020) · cites this paper as Smith and Haythornthwaite, 2004
Sleep disorders are among the most common concerns related to pain.
“Sleep disorders are among the most common concerns related to pain [73].”
From ACTsmart: Guided Smartphone-Delivered Acceptance and Commitment Therapy for Chronic Pain—A Pilot Trial. (2021) · cites this paper as [73]
Between 50% and 88% of patients with chronic pain report problems with sleep.
“between 50% and 88% of patients with chronic pain report problems with sleep (Smith & Haythornthwaite, 2004).”
From Hypnotic approaches for chronic pain management: Clinical implications of recent research findings. (2014) · cites this paper as Smith & Haythornthwaite, 2004

The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234 · see citing works
Epidemiologic study of sleep disturbances and psychiatric disorders. An opportunity for prevention?
Ford, D. E. (1989) · JAMA · doi:10.1001/jama.262.11.1479 · Cited by 2,440 · see citing works
Epidemiologic Study of Sleep Disturbances and Psychiatric Disorders: An Opportunity for Prevention?
Ford, D. E. (1989) · JAMA · doi:10.1001/jama.1989.03430110069030 · Cited by 2,252 · see citing works
Sleep disturbance and psychiatric disorders: A longitudinal epidemiological study of young Adults
Breslau, N., Roth, T., Rosenthal, L., & Andreski, P. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00188-3 · Cited by 1,831 · see citing works
The functional states of the thalamus and the associated neuronal interplay.
Steriade, M., & Llinas, R. R. (1988) · Physiological Reviews · doi:10.1152/physrev.1988.68.3.649 · Cited by 1,746 · see citing works
Systematic review and meta-analysis of randomized controlled trials of cognitive behaviour therapy and behaviour therapy for chronic pain in adults, excluding headache
Morley, S., Eccleston, C., & Williams, A. (1999) · Pain · doi:10.1016/s0304-3959(98)00255-3 · Cited by 1,597 · see citing works
Gabapentin for the Treatment of Postherpetic Neuralgia A Randomized Controlled Trial
Rowbotham, M. C. (1998) · JAMA · doi:10.1001/jama.280.21.1837 · Cited by 1,418 · see citing works
A behavioral perspective on insomnia treatment
Spielman, A. J., Caruso, L. S., & Glovinsky, P. B. (1987) · Psychiatric Clinics of North America · doi:10.1016/s0193-953x(18)30532-x · Cited by 1,261 · see citing works
Behavioral and Pharmacological Therapies for Late-Life Insomnia: A Randomized Controlled Trial
Morin, C. M., Colecchi, C., Stone, J., Sood, R., & Brink, D. (1999) · JAMA · doi:10.1001/jama.281.11.991 · Cited by 1,095 · see citing works
Treatment of Chronic Insomnia by Restriction of Time in Bed
(1987) · Sleep · doi:10.1093/sleep/10.1.45 · Cited by 948 · see citing works
Comparative Meta-Analysis of Pharmacotherapy and Behavior Therapy for Persistent Insomnia
Smith, M. T., Perlis, M. L., Park, A., Smith, M. S., Pennington, J., Giles, D. E., & Buysse, D. J. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.1.5 · Cited by 863 · see citing works
Musculosketal Symptoms and Non-REM Sleep Disturbance in Patients with “Fibrositis Syndrome” and Healthy Subjects
Moldofsky, H., Scarisbrick, P., England, R. W., & SMYTHE, H. A. (1975) · Psychosomatic Medicine · doi:10.1097/00006842-197507000-00008 · Cited by 851 · see citing works
Identifying effective psychological treatments for insomnia: A meta-analysis.
Murtagh, D. R. R., & Greenwood, K. M. (1995) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.63.1.79 · Cited by 664 · see citing works
Cognitive Behavioral Therapy for Treatment of Chronic Primary Insomnia: A Randomized Controlled Trial
Edinger, J. D., Wohlgemuth, W. K., Radtke, R. A., Marsh, G. R., & Quillian, R. E. (2001) · JAMA · doi:10.1001/jama.285.14.1856 · Cited by 625 · see citing works
Cognitive Behavior Therapy for Depression in Type 2 Diabetes Mellitus: A Randomized, Controlled Trial
Lustman, P. J., Griffith, L. S., Freedland, K. E., Kissel, S. S., & Clouse, R. E. (1998) · Annals of Internal Medicine · doi:10.7326/0003-4819-129-8-199810150-00005 · Cited by 562 · see citing works
Induction of Neurasthenic Musculoskeletal Pain Syndrome by Selective Sleep Stage Deprivation
Moldofsky, H., & Scarisbrick, P. (1976) · Psychosomatic Medicine · doi:10.1097/00006842-197601000-00006 · Cited by 560 · see citing works
The Pittsburgh Sleep Diary
Monk, T. H., Reynolds, C. F., Kupfer, D. J., Buysse, D. J., Coble, P. A., HAYES, A. J., Machen, M. A., PETRIE, S. R., & Ritenour, A. (1994) · Journal of Sleep Research · doi:10.1111/j.1365-2869.1994.tb00114.x · Cited by 537 · see citing works
The effects of total sleep deprivation, selective sleep interruption and sleep recovery on pain tolerance thresholds in healthy subjects
Onen, S. ‐., Alloui, A., Gross, A. S., Eschalier, A., & Dubray, C. (2001) · Journal of Sleep Research · doi:10.1046/j.1365-2869.2001.00240.x · Cited by 512 · see citing works
Clinical correlates of insomnia in patients with chronic illness
Katz, D. A., & McHorney, C. A. (1998) · Archives of Internal Medicine · doi:10.1001/archinte.158.10.1099 · Cited by 480 · see citing works
Sequential daily relations of sleep, pain intensity, and attention to pain among women with fibromyalgia
Affleck, G. G., URROWS, S. T., Tennen, H. A., Higgins, P. S., & Abeles, M. (1996) · Pain · doi:10.1016/s0304-3959(96)03226-5 · Cited by 467 · see citing works
Quality of life in people with insomnia.
Zammit, G. K., Weiner, J., Damato, N., Sillup, G. P., & McMillan, C. A. (1999) · PubMed · Cited by 467 · see citing works
Management of Chronic Tension-Type Headache With Tricyclic Antidepressant Medication, Stress Management Therapy, and Their Combination: A Randomized Controlled Trial
Holroyd, K. A., O'Donnell, F. J., Stensland, M., Lipchik, G. L., Cordingley, G. E., & Carlson, B. W. (2001) · JAMA · doi:10.1001/jama.285.17.2208 · Cited by 457 · see citing works
Self-Reported Sleep and Mood Disturbance in Chronic Pain Patients
Morin, C. M., Gibson, D., & Wade, J. B. (1998) · Clinical Journal of Pain · doi:10.1097/00002508-199812000-00007 · Cited by 380 · see citing works
Sleep problems and their correlates in a working population
Kuppermann, M., Lubeck, D. P., Mazonson, P. D., Patrick, D. L., Stewart, A. L., Buesching, D. P., & Filer, S. K. (1995) · Journal of General Internal Medicine · doi:10.1007/bf02599573 · Cited by 341 · see citing works
Effects of selective slow wave sleep disruption on musculoskeletal pain and fatigue in middle aged women.
Lentz, M. J., Landis, C. A., Rothermel, J., & Shaver, J. L. F. (1999) · PubMed · Cited by 333 · see citing works
Effects of Aerobic Exercise Versus Stress Management Treatment in Fibromyalgia
Wigers, S. H., Stiles, T. C., & Vogel, P. A. (1996) · Scandinavian Journal of Rheumatology · doi:10.3109/03009749609069212 · Cited by 328 · see citing works
Economic effects of insomnia.
Stoller, M. K. (1995) · PubMed · Cited by 322 · see citing works
Does sleep disturbance predict depression in elderly people? A study in inner London.
Livingston, G., Blizard, B., & Mann, A. (1993) · PubMed · Cited by 313 · see citing works
Stimulus Control Instructions
Bootzin, R. R., Epstein, D. R., & Wood, J. M. (1991) · Springer eBooks · doi:10.1007/978-1-4757-9586-8_2 · Cited by 307 · see citing works
Sleep quality and presleep arousal in chronic pain
Smith, M. T., Perlis, M. L., Smith, M. S., Giles, D. E., & Carmody, T. P. (2000) · Journal of Behavioral Medicine · doi:10.1023/a:1005444719169 · Cited by 302 · see citing works
Cognitive–behavioral treatment of insomnia secondary to chronic pain.
Currie, S. R., Wilson, K. G., Pontefract, A. J., & deLaplante, L. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.68.3.407 · Cited by 301 · see citing works
Cognitive-behavioral treatment of insomnia secondary to chronic pain.
Currie, S. R., Wilson, K. G., Pontefract, A. J., & deLaplante, L. (2000) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.68.3.407 · Cited by 299 · see citing works
Quality of sleep and its daily relationship to pain intensity in hospitalized adult burn patients
Raymond, I., Nielsen, T., Lavigne, G. J., Manzini, C., & Choinière, M. (2001) · Pain · doi:10.1016/s0304-3959(01)00282-2 · Cited by 279 · see citing works
Stimulus Control Treatment for Insomnia
Bootzin, R. R. (1973) · PsycEXTRA Dataset · doi:10.1037/e465522008-198 · Cited by 279 · see citing works
Cognitive-behavior therapy for late-life insomnia.
Morin, C. M., Kowatch, R. A., Barry, T., & Walton, E. (1993) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.61.1.137 · Cited by 274 · see citing works
Major depression and insomnia in chronic pain
Wilson, K. G., Eriksson, M. Y., D'Eon, J. L., Mikail, S. F., & Emery, P. C. (2002) · The Clinical Journal of Pain · doi:10.1097/00002508-200203000-00002 · Cited by 267 · see citing works
Sleep disturbance in pain clinic patients
Pilowsky, I., Crettenden, I., & Townley, M. (1985) · Pain · doi:10.1016/0304-3959(85)90227-1 · Cited by 257 · see citing works
The experience of rheumatoid arthritis pain and fatigue: Examining momentary reports and correlates over one week
Stone, A. A., Broderick, J. E., Porter, L. S., & Kaell, A. T. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1790100306 · Cited by 240 · see citing works
Sleep Disturbance and Nonmalignant Chronic Pain: A Comprehensive Review of the Literature
Menefee, L. A., Cohen, M. J. M., Anderson, W. R., Doghramji, K., Frank, E. D., & Lee, H. B. (2000) · Pain Medicine · doi:10.1046/j.1526-4637.2000.00022.x · Cited by 234 · see citing works
Psychological treatment of secondary insomnia.
Lichstein, K. L., Wilson, N. M., & Johnson, C. T. (2000) · Psychology and Aging · doi:10.1037//0882-7974.15.2.232 · Cited by 234 · see citing works
Longitudinal relationships among pain, sleep problems, and depression in rheumatoid arthritis.
Nicassio, P. M., & Wallston, K. A. (1992) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.101.3.514 · Cited by 225 · see citing works
Cognitive-behavior therapy for late-life insomnia.
Morin, C. M., Kowatch, R. A., Barry, T., et al. (1993) · Journal of Consulting and Clinical Psychology · doi:10.1037/0022-006x.61.1.137 · Cited by 211 · see citing works
Treatment outcome of chronic non-malignant pain patients managed in a Danish multidisciplinary pain centre compared to general practice: a randomised controlled trial
Becker, N., Sjøgren, P., Bech, P., Olsen, A. K., & Eriksen, J. (2000) · Pain · doi:10.1016/s0304-3959(99)00209-2 · Cited by 205 · see citing works
Case Studies in Insomnia
(1991) · Springer eBooks · doi:10.1007/978-1-4757-9586-8 · Cited by 198 · see citing works
Daily diary and ambulatory activity monitoring of sleep in patients with insomnia associated with chronic musculoskeletal pain
Wilson, K. G., Watson, S. T., & Currie, S. R. (1998) · Pain · doi:10.1016/s0304-3959(97)00207-8 · Cited by 186 · see citing works
Psychological treatment of secondary insomnia
Lichstein, K. L., Wilson, N. M., & Johnson, C. T. (2000) · Psychology and Aging · doi:10.1037/0882-7974.15.2.232 · Cited by 184 · see citing works
Importance of the ventrolateral region of the periaqueductal gray and adjacent tegmentum in the control of paradoxical sleep as studied by muscimol microinjections in the cat
Sastre, J., Buda, C., Kitahama, K., & Jouvet, M. (1996) · Neuroscience · doi:10.1016/0306-4522(96)00190-x · Cited by 173 · see citing works
Prevalence and Persistence of Sleep Complaints in a Rural Older Community Sample: The MoVIES Project
Ganguli, M., Reynolds, C. F., & Gilby, J. E. (1996) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1996.tb03733.x · Cited by 163 · see citing works
The socioeconomic impact of chronic pain
Latham, J., & Davis, B. (1994) · Disability and Rehabilitation · doi:10.3109/09638289409166435 · Cited by 162 · see citing works
Development of a sleep diary for chronic pain patients
Haythornthwaite, J. A., Hegel, M. T., & Kerns, R. D. (1991) · Journal of Pain and Symptom Management · doi:10.1016/0885-3924(91)90520-e · Cited by 161 · see citing works
Subjective Sleep Disturbance in Chronic Back Pain
Atkinson, J. H., Ancoli‐Israel, S., Slater, M. A., Garfin, S. R., & Gillin, C. (1988) · Clinical Journal of Pain · doi:10.1097/00002508-198812000-00007 · Cited by 156 · see citing works
Sleep arousal response to experimental thermal stimulation during sleep in human subjects free of pain and sleep problems
Lavigne, G. J., Zucconi, M., Castronovo, C., Manzini, C., Marchettini, P., & Smirne, S. (2000) · Pain · doi:10.1016/s0304-3959(99)00213-4 · Cited by 153 · see citing works
Efficacy of behavioral versus triazolam treatment in persistent sleep-onset insomnia
(1991) · American Journal of Psychiatry · doi:10.1176/ajp.148.1.121 · Cited by 152 · see citing works
The effects of delta wave sleep interruption on pain thresholds and fibromyalgia-like symptoms in healthy subjects; correlations with insulin-like growth factor I.
Older, S. A., Battafarano, D. F., Danning, C. L., Ward, J., Grady, E. P., Derman, S., & Russell, I. J. (1998) · PubMed · Cited by 147 · see citing works
Brainstem modulation of pain during sleep and waking
Foo, H., & Mason, P. (2003) · Sleep Medicine Reviews · doi:10.1053/smrv.2002.0224 · Cited by 145 · see citing works
Temporal and Spatial Dynamics of Human Forebrain Activity During Heat Pain: Analysis by Positron Emission Tomography
Casey, K. L., Morrow, T., Lorenz, J., & Minoshima, S. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.85.2.951 · Cited by 145 · see citing works
Active and placebo treatment effects on moderate insomnia under counterdemand and positive demand instructions.
Steinmark, S. W., & Borkovec, T. D. (1974) · Journal of Abnormal Psychology · doi:10.1037/h0036489 · Cited by 142 · see citing works
Sleep in Fibromyalgia Patients: Subjective and Objective Findings
Harding, S. M. (1998) · The American Journal of the Medical Sciences · doi:10.1016/s0002-9629(15)40354-4 · Cited by 138 · see citing works
Alpha EEG sleep and morning symptoms in rheumatoid arthritis.
Moldofsky, H., Lue, F. A., & SMYTHE, H. A. (1983) · PubMed · Cited by 138 · see citing works
The Effect of Cutaneous and Deep Pain on the Electroencephalogram During Sleep—An Experimental Study
Drewes, A. M., Dremstrup, K., Arendt‐Nielsen, L., Birket‐Smith, L., & Hansen, L. M. (1997) · SLEEP · doi:10.1093/sleep/20.8.632 · Cited by 137 · see citing works
The epidemiology and treatment of depression when it coexists with somatoform disorders, somatization, or pain
Smith, G. R. (1992) · General Hospital Psychiatry · doi:10.1016/0163-8343(92)90097-t · Cited by 134 · see citing works
Disturbed Sleep in Patients Complaining of Chronic Pain
Wittig, R. M., Zorick, F. J., Blumer, D. P., Heilbronn, M., & Roth, T. G. (1982) · The Journal of Nervous and Mental Disease · doi:10.1097/00005053-198207000-00011 · Cited by 134 · see citing works
Sleep and headache
Jennum, P., & Jensen, R. (2002) · Sleep Medicine Reviews · doi:10.1053/smrv.2001.0223 · Cited by 121 · see citing works
Role of glutamate receptors and nitric oxide in the rostral ventromedial medulla in visceral hyperalgesia
Coutinho, V., Urban, O. M., & Gebhart, F. (1998) · Pain · doi:10.1016/s0304-3959(98)00137-7 · Cited by 119 · see citing works
Validation of the WHOQOL-100: Pain Management Improves Quality of Life for Chronic Pain Patients
Skevington, S. M., Carse, M. S., & Williams, A. C. D. C. (2001) · Clinical Journal of Pain · doi:10.1097/00002508-200109000-00013 · Cited by 115 · see citing works
Alternative diagnostic criteria for major depressive disorder in patients with chronic pain
Wilson, K. G., Mikail, S. F., D’Eon, J. L., & Minns, J. E. (2001) · Pain · doi:10.1016/s0304-3959(00)00440-1 · Cited by 113 · see citing works
A pilot study of cognitive behavioral therapy in fibromyalgia.
Singh, B., Berman, B. M., Hadhazy, V., & Creamer, P. (1998) · PubMed · Cited by 102 · see citing works
Treatment of insomnia in cancer patients using muscle relaxation training
Cannici, J. P., Malcolm, R. J., & Peek, L. A. (1983) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(83)90056-3 · Cited by 100 · see citing works
Presleep Cognitions in Patients with Insomnia Secondary to Chronic Pain
Smith, M. T., Perlis, M. L., Carmody, T. P., Smith, M. S., & Giles, D. E. (2001) · Journal of Behavioral Medicine · doi:10.1023/a:1005690505632 · Cited by 95 · see citing works
Behavioral management of sleep disturbances secondary to chronic pain
Morin, C. M., Kowatch, R. A., & Wade, J. B. (1989) · Journal of Behavior Therapy and Experimental Psychiatry · doi:10.1016/0005-7916(89)90060-8 · Cited by 94 · see citing works
Home-based central nervous system assessment of a multifactor behavioral intervention for chronic sleep-onset insomnia
Jacobs, G. D., Benson, H., & Friedman, R. (1993) · Behavior Therapy · doi:10.1016/s0005-7894(05)80261-8 · Cited by 93 · see citing works
A longitudinal study of clinical symptoms and sleep parameters in rheumatoid arthritis
Drewes, A. M., Nielsen, K. D., Hansen, B., Taagholt, S. J., Bjerregård, K., & Svendsen, L. (2000) · Lara D. Veeken · doi:10.1093/rheumatology/39.11.1287 · Cited by 92 · see citing works
SLEEP INTENSITY IN FIBROMYALGIA: FOCUS ON THE MICROSTRUCTURE OF THE SLEEP PROCESS
Drewes, A. M., NIELSEN, K. D., Taagholt, S. J., Bjerregård, K., Svendsen, L., & Gade, J. (1995) · Lara D. Veeken · doi:10.1093/rheumatology/34.7.629 · Cited by 90 · see citing works
A Biopsychosocial Overview of Pretreatment Screening of Patients With Pain
Gatchel, R. J. (2001) · Clinical Journal of Pain · doi:10.1097/00002508-200109000-00002 · Cited by 90 · see citing works
Musculoskeletal Pain and its Socioeconomic Implications
Katz, W. A. (2002) · Clinical Rheumatology · doi:10.1007/s100670200028 · Cited by 89 · see citing works
Fibromyalgia, Sleep Disorder and Chronic Fatigue Syndrome
Moldofsky, H. (2007) · Novartis Foundation symposium · doi:10.1002/9780470514382.ch15 · Cited by 80 · see citing works
Long-term changes in behavior and regional cerebral blood flow associated with painful peripheral mononeuropathy in the rat
Paulson, P. E., Casey, K. L., & Morrow, T. (2002) · Pain · doi:10.1016/s0304-3959(01)00370-0 · Cited by 80 · see citing works
Sleep Disturbance in Orofacial Pain Patients: Pain-Related or Emotional Distress?
Riley, J. L., Benson, M. B., Gremillion, H. A., Myers, C. D., Robinson, M. E., Smith, C. S., & Waxenberg, L. B. (2001) · CRANIO® · doi:10.1080/08869634.2001.11746159 · Cited by 79 · see citing works
Onset of nocturnal attacks of chronic cluster headache in relation to sleep stages
Pfaffenrath, V., Pöllmann, W., Rüther, E., Lund, R., & Hajak, G. (1986) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1986.tb03296.x · Cited by 75 · see citing works
Sleep in Fibromyalgia Patients: Subjective and Objective Findings
Harding, S. M. (1998) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199806000-00005 · Cited by 74 · see citing works
Nighttime sleep and daytime functioning (sleepiness and fatigue) in less well-defined chronic rheumatic diseases with particular reference to the ‘alpha-delta NREM sleep anomaly’
Mahowald, M. L., & Mahowald, M. W. (2000) · Sleep Medicine · doi:10.1016/s1389-9457(00)00028-9 · Cited by 73 · see citing works
Antinociception and behavioral changes induced by carbachol microinjected into identified sites of the rat brain
Klamt, J. G., & Prado, W. A. (1991) · Brain Research · doi:10.1016/0006-8993(91)90593-k · Cited by 64 · see citing works
The relationship between selective sleep deprivation, nocturnal jaw‐muscle activity and pain in healthy men
Arima, T., Svensson, P. J., Rasmussen, C., Nielsen, K. D., Drewes, A. M., & Arendt‐Nielsen, L. (2001) · Journal of Oral Rehabilitation · doi:10.1046/j.1365-2842.2001.00687.x · Cited by 62 · see citing works
Nocturnal Sleep Recording with Cassette EEG in Chronic Headaches
Drake, M. E., Pakalnis, A., Andrews, J. M., & Bogner, J. E. (1990) · Headache The Journal of Head and Face Pain · doi:10.1111/j.1526-4610.1990.hed3009600.x · Cited by 61 · see citing works
Sleep and chronic pain
Rains, J. C., & Penzien, D. B. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(02)00545-7 · Cited by 58 · see citing works
Sleep in chronic pain: problems and treatments
Cohen, M. J. M., Menefee, L. A., Doghramji, K., Anderson, W. R., & Frank, E. D. (2000) · International Review of Psychiatry · doi:10.1080/09540260050007435 · Cited by 54 · see citing works
Effects of Sleep on Spinal Nociceptive Reflexes in Humans
Sandrini, G., Milanov, I. G., Rossi, B., Murri, L., Alfonsi, E., Moglia, A., & Nappi, G. (2001) · SLEEP · doi:10.1093/sleep/24.1.13 · Cited by 50 · see citing works
Heart rate changes during sleep in response to experimental thermal (nociceptive) stimulations in healthy subjects
Lavigne, G. J., Zucconi, M., Castronovo, V., Manzini, C., Veglia, F., Smirne, S., & Ferini‐Strambi, L. (2001) · Clinical Neurophysiology · doi:10.1016/s1388-2457(00)00558-7 · Cited by 48 · see citing works
STUDIES ON THE PHYSIOLOGY OF SLEEP
Cooperman, N. R., Mullin, F. J., & Kleitman, N. (1934) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1934.107.3.589 · Cited by 47 · see citing works
Sleep Restriction for the Inpatient Treatment of Insomnia
Morin, C. M., Kowatch, R. A., & O’Shanick, G. J. (1990) · SLEEP · doi:10.1093/sleep/13.2.183 · Cited by 44 · see citing works
Cognitive-behavioral therapy in patients with ankylosing spondylitis in a German self-help organization
Basler, H.-D., & Rehfisch, H. P. (1991) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(91)90089-7 · Cited by 44 · see citing works
Differential cholinergic activation of G proteins in rat and mouse brainstem: Relevance for sleep and nociception
DeMarco, G. J., Baghdoyan, H. A., & Lydic, R. (2003) · The Journal of Comparative Neurology · doi:10.1002/cne.10548 · Cited by 41 · see citing works
Triazolam improves sleep but fails to alter pain in TMD patients.
DeNucci, D. J., Sobiski, C., & Dionne, R. A. (1998) · PubMed · Cited by 35 · see citing works
Ambulatory Recording and Power Spectral Analysis by Autoregressive Modelling of Polygraphic Sleep Signals in Patients Suffering from Chronic Pain
Drewes, A. M., Svendsen, L., Bjerregård, K., Taagholt, S. J., & Nielsen, K. D. (1994) · Methods of Information in Medicine · doi:10.1055/s-0038-1634963 · Cited by 15 · see citing works
Quality of Well-Being Scale and Chronic Low Back Pain
Smith, M. T., Carmody, T. P., & Smith, M. S. (2000) · Journal of Clinical Psychology in Medical Settings · doi:10.1023/a:1009512813102 · Cited by 14 · see citing works
Immunomodulatory effects of anti-tumor necrosis factor alpha therapy on synovium in spondylarthropathy: histologic findings in eight patients from an open-label pilot study
Warrington (2001) · Pure Amsterdam UMC · doi:10.1002/1529-0131(200101)44:1 · Cited by 2 · see citing works

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The association of sleep and pain: an update and a path forward
Finan, P. H., Goodin, B. R., & Smith, M. T. (2013) · The Journal of Pain · doi:10.1016/j.jpain.2013.08.007 · Cited by 1,620 · see citing works
Self-citation
Cognitive Behavioral Therapy for Chronic Insomnia: A Systematic Review and Meta-analysis
Trauer, J. M., Qian, M. Y., Doyle, J. S., Rajaratnam, S. M. W., & Cunnington, D. (2015) · Annals of Internal Medicine · doi:10.7326/m14-2841 · Cited by 1,053 · see citing works
Chronic insomnia
Morin, C. M., & Benca, R. (2012) · The Lancet · doi:10.1016/s0140-6736(11)60750-2 · Cited by 976 · see citing works
The Burden of Chronic Low Back Pain: Clinical Comorbidities, Treatment Patterns, and Health Care Costs in Usual Care Settings
Gore, M., Sadosky, A., Stacey, B., Tai, K.-S., & Leslie, D. (2012) · Spine · doi:10.1097/brs.0b013e318241e5de · Cited by 650 · see citing works
Sleep deprivation and pain perception
LAUTENBACHER, S., KUNDERMANN, B., & KRIEG, J. (2006) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2005.08.001 · Cited by 613 · see citing works
Astrocytes in chronic pain and itch
Ji, R., Donnelly, C. R., & Nedergaard, M. (2019) · Nature reviews. Neuroscience · doi:10.1038/s41583-019-0218-1 · Cited by 553 · see citing works
The effects of sleep deprivation on pain inhibition and spontaneous pain in women
Smith, M. T., Edwards, R. R., McCann, U. D., & Haythornthwaite, J. A. (2007) · Sleep · doi:10.1093/sleep/30.4.494 · Cited by 539 · see citing works
Self-citation
Sleep loss and inflammation
Mullington, J. M., Simpson, N. S., Meier-Ewert, H. K., & Haack, M. (2010) · Best Practice & Research Clinical Endocrinology & Metabolism · doi:10.1016/j.beem.2010.08.014 · Cited by 519 · see citing works
Neuropathic pain: a practical guide for the clinician
Gilron, I. (2006) · Canadian Medical Association Journal · doi:10.1503/cmaj.060146 · Cited by 451 · see citing works
Prevalence and correlates of clinical insomnia co‐occurring with chronic back pain
TANG, N. K. Y., WRIGHT, K. J., & SALKOVSKIS, P. M. (2007) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2007.00571.x · Cited by 383 · see citing works
The comorbidity of insomnia, chronic pain, and depression: Dopamine as a putative mechanism
Finan, P. H., & Smith, M. T. (2012) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2012.03.003 · Cited by 367 · see citing works
Assessment of Psychosocial and Functional Impact of Chronic Pain
Turk, D. C., Fillingim, R. B., Ohrbach, R., & Patel, K. V. (2016) · The Journal of Pain · doi:10.1016/j.jpain.2016.02.006 · Cited by 350 · see citing works
The Association Between Chronic Low Back Pain and Sleep
Kelly, G. A., Blake, C. M., Power, C. K., O'Keeffe, D., & Fullen, B. M. (2010) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e3181f3bdd5 · Cited by 335 · see citing works
Cognitive Behavioral Therapy for Insomnia Improves Sleep and Decreases Pain in Older Adults with Co-Morbid Insomnia and Osteoarthritis
Vitiello, M. V., Rybarczyk, B., Von Korff, M., & Stepanski, E. J. (2009) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27547 · Cited by 321 · see citing works
Duration of sleep contributes to next-day pain report in the general population
Edwards, R. R., Almeida, D. M., Klick, B., Haythornthwaite, J. A., & Smith, M. T. (2008) · Pain · doi:10.1016/j.pain.2008.01.025 · Cited by 321 · see citing works
Sleep and rheumatologic disorders
Abad, V. C., Sarinas, P. S. A., & Guilleminault, C. (2008) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2007.09.001 · Cited by 309 · see citing works
Sleep disturbances and sleep disorders in adults living with chronic pain: a meta-analysis
Mathias, J. L., Cant, M. L., & Burke, A. L. J. (2018) · Sleep Medicine · doi:10.1016/j.sleep.2018.05.023 · Cited by 305 · see citing works
Perspective on diffuse noxious inhibitory controls as a model of endogenous pain modulation in clinical pain syndromes
van Wijk, G., & Veldhuijzen, D. S. (2010) · The Journal of Pain · doi:10.1016/j.jpain.2009.10.009 · Cited by 281 · see citing works
Prevalence of chronic pain seven years following limb threatening lower extremity trauma ☆
Castillo, R. C., MacKenzie, E. J., Wegener, S. T., & Bosse, M. J. (2006) · Pain · doi:10.1016/j.pain.2006.04.020 · Cited by 265 · see citing works
Psychological therapies for the management of chronic pain
Sturgeon, J. (2014) · Psychology Research and Behavior Management · doi:10.2147/prbm.s44762 · Cited by 259 · see citing works
Effects of sleep changes on pain-related health outcomes in the general population: A systematic review of longitudinal studies with exploratory meta-analysis
Afolalu, E. F., Ramlee, F., & Tang, N. K. Y. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.08.001 · Cited by 262 · see citing works
Sedentary Behavior and Sleep Problems: a Systematic Review and Meta-Analysis
Yan, Y., Shin, J. C., Li, D., & An, R. (2016) · International Journal of Behavioral Medicine · doi:10.1007/s12529-016-9609-0 · Cited by 228 · see citing works
Napping: a public health issue. From epidemiological to laboratory studies
Faraut, B., Andrillon, T., Vecchierini, M.-F., & Leger, D. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2016.09.002 · Cited by 217 · see citing works
A systematic review and meta-analysis of cognitive and behavioral interventions to improve sleep health in adults without sleep disorders
Murawski, B., Wade, L., Plotnikoff, R. C., Lubans, D. R., & Duncan, M. J. (2017) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.12.003 · Cited by 225 · see citing works
Sleep Disturbance and Pain
Andersen, M. L., Araujo, P., Frange, C., & Tufik, S. (2018) · CHEST Journal · doi:10.1016/j.chest.2018.07.019 · Cited by 218 · see citing works
Cancer pain, fatigue, distress, and insomnia in cancer patients
Theobald, D. (2004) · Clinical cornerstone · doi:10.1016/s1098-3597(05)80003-1 · Cited by 217 · see citing works
Sleep, Pain Catastrophizing, and Central Sensitization in Knee Osteoarthritis Patients With and Without Insomnia
Campbell, C. M., Buenaver, L. F., Finan, P. H., Bounds, S. C., Redding, M., McCauley, L., Robinson, M., Edwards, R. R., & Smith, M. T. (2015) · Arthritis Care & Research · doi:10.1002/acr.22609 · Cited by 214 · see citing works
The Canadian STOP-PAIN project – Part 1: Who are the patients on the waitlists of multidisciplinary pain treatment facilities?
Choinière, M., Dion, D., Peng, P., Banner, R., Barton, P. M., Boulanger, A., Clark, A. J., GORDON, A. S., Guerriere, D. N., Guertin, M., et al. (2010) · Canadian Journal of Anesthesia/Journal canadien d anesthésie · doi:10.1007/s12630-010-9305-5 · Cited by 213 · see citing works
Background Noise
Bakitas, M. A. (2007) · Nursing Research · doi:10.1097/01.nnr.0000289503.22414.79 · Cited by 213 · see citing works
Cognitive behavioral therapy for insomnia in patients with chronic pain-A systematic review and meta-analysis of randomized controlled trials
Selvanathan, J., Pham, C., Nagappa, M., Peng, P. W. H., Englesakis, M., Espie, C. A., Morin, C. M., & Chung, F. (2021) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2021.101460 · Cited by 206 · see citing works
Exploring the role of sleep and coping in quality of life in fibromyalgia
Theadom, A., Cropley, M., & Humphrey, K.-L. (2007) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2006.09.013 · Cited by 198 · see citing works
Hypnotic approaches for chronic pain management: Clinical implications of recent research findings.
Jensen, M. P., & Patterson, D. R. (2014) · American Psychologist · doi:10.1037/a0035644 · Cited by 195 · see citing works
“For example, between 50% and 88% of patients with chronic pain report problems with sleep (Smith & Haythornthwaite, 2004).”
Background
Correlation of Postoperative Pain to Quality of Recovery in the Immediate Postoperative Period
Wu, C. L., Rowlingson, A. J., Partin, A. W., Kalish, M. A., Courpas, G. E., Walsh, P. C., & FLEISHER, L. (2005) · Regional Anesthesia & Pain Medicine · doi:10.1016/j.rapm.2005.07.190 · Cited by 194 · see citing works
Estimation of the global prevalence and burden of insomnia: a systematic literature review-based analysis
Benjafield, A., Kuniyoshi, F. H. S., Malhotra, A., Martin, J. L., Morin, C. M., Maurer, L., Cistulli, P. A., Pépin, J., & Wickwire, E. M. (2025) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2025.102121 · Cited by 217 · see citing works
Dissemination of CBTI to the Non-Sleep Specialist: Protocol Development and Training Issues
Manber, R., Carney, C., Edinger, J., Epstein, D., Friedman, L., Haynes, P. L., Karlin, B. E., Pigeon, W., Siebern, A. T., & Trockel, M. (2012) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.1786 · Cited by 178 · see citing works
Sleep and Pain
Whibley, D., AlKandari, N., Kristensen, K., Barnish, M. S., Rzewuska, M., Druce, K. L., & Tang, N. K. Y. (2019) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000697 · Cited by 184 · see citing works
The Pain of Sleep Loss: A Brain Characterization in Humans
Krause, A. J., Prather, A. A., Wager, T. D., Lindquist, M. A., & Walker, M. P. (2019) · Journal of Neuroscience · doi:10.1523/jneurosci.2408-18.2018 · Cited by 178 · see citing works
Sleep Impairment in Patients With Painful Diabetic Peripheral Neuropathy
Zelman, D. C., Brandenburg, N. A., & Gore, M. R. (2006) · Clinical Journal of Pain · doi:10.1097/01.ajp.0000210910.49923.09 · Cited by 175 · see citing works
Nonpharmacological Treatments of Insomnia for Long-Term Painful Conditions: A Systematic Review and Meta-analysis of Patient-Reported Outcomes in Randomized Controlled Trials
Tang, N. K. Y., Lereya, S. T., Boulton, H., Miller, M. A., Wolke, D., & Cappuccio, F. P. (2015) · Sleep · doi:10.5665/sleep.5158 · Cited by 176 · see citing works
Short-term improvement in insomnia symptoms predicts long-term improvements in sleep, pain, and fatigue in older adults with comorbid osteoarthritis and insomnia
Vitiello, M. V., McCurry, S. M., Shortreed, S. M., Baker, L. D., Rybarczyk, B. D., Keefe, F. J., & Von Korff, M. (2014) · Pain · doi:10.1016/j.pain.2014.04.032 · Cited by 171 · see citing works
Cognitive‐Behavioral Treatment for Comorbid Insomnia and Osteoarthritis Pain in Primary Care: The Lifestyles Randomized Controlled Trial
Vitiello, M. V., McCurry, S. M., Shortreed, S. M., Balderson, B. H., Baker, L. D., Keefe, F. J., Rybarczyk, B. D., & Von Korff, M. (2013) · Journal of the American Geriatrics Society · doi:10.1111/jgs.12275 · Cited by 165 · see citing works
Quality of sleep in patients with chronic low back pain: a case-control study
Marty, M., Rozenberg, S., Duplan, B., Thomas, P. L., Duquesnoy, B., Allaert, F., & de Rhumatologie, T. S. R. D. L. S. F. (2008) · European Spine Journal · doi:10.1007/s00586-008-0660-7 · Cited by 164 · see citing works
The symptom cluster of sleep, fatigue and depressive symptoms in breast cancer patients: severity of the problem and treatment options
Fiorentino, L., Rissling, M. B., Liu, L., & Ancoli‐Israel, S. (2011) · Drug Discovery Today Disease Models · doi:10.1016/j.ddmod.2011.05.001 · Cited by 162 · see citing works
Sleep continuity and architecture: Associations with pain‐inhibitory processes in patients with temporomandibular joint disorder
Edwards, R. R., Grace, E., Peterson, S., Klick, B., Haythornthwaite, J. A., & Smith, M. T. (2009) · European Journal of Pain · doi:10.1016/j.ejpain.2008.12.007 · Cited by 158 · see citing works
Activation of the prostaglandin system in response to sleep loss in healthy humans: Potential mediator of increased spontaneous pain
Haack, M., Lee, E., Cohen, D. A., & Mullington, J. M. (2009) · Pain · doi:10.1016/j.pain.2009.05.029 · Cited by 158 · see citing works
Sleep restriction attenuates amplitudes and attentional modulation of pain-related evoked potentials, but augments pain ratings in healthy volunteers
Tiede, W., Magerl, W., Baumgärtner, U., Durrer, B., Ehlert, U., & Treede, R.-D. (2010) · Pain · doi:10.1016/j.pain.2009.08.029 · Cited by 153 · see citing works
Mechanisms by which sleep disturbance contributes to osteoarthritis pain: A conceptual model
Smith, M. T., Quartana, P. J., Okonkwo, R., & Nasir, A. (2009) · Current Pain and Headache Reports · doi:10.1007/s11916-009-0073-2 · Cited by 152 · see citing works
The Coexistence of Neuropathic Pain, Sleep, and Psychiatric Disorders
Argoff, C. E. (2006) · Clinical Journal of Pain · doi:10.1097/01.ajp.0000210945.27052.b3 · Cited by 149 · see citing works
Total sleep deprivation increases pain sensitivity, impairs conditioned pain modulation and facilitates temporal summation of pain in healthy participants
Staffe, A. T., Bech, M. W., Clemmensen, S. L. K., Nielsen, H. T., Larsen, D. B., & Petersen, K. K. (2019) · PLoS ONE · doi:10.1371/journal.pone.0225849 · Cited by 150 · see citing works
Negative Mood Mediates the Effect of Poor Sleep on Pain Among Chronic Pain Patients
O’Brien, E. M., Waxenberg, L. B., Atchison, J. W., Gremillion, H. A., Staud, R. M., McCrae, C. S., & Robinson, M. E. (2010) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e3181c328e9 · Cited by 146 · see citing works
Deployment-Related Insomnia in Military Personnel and Veterans
Bramoweth, A. D., & Germain, A. (2013) · Current Psychiatry Reports · doi:10.1007/s11920-013-0401-4 · Cited by 144 · see citing works
Chronic Pain and Sleep Disturbances: A Pragmatic Review of Their Relationships, Comorbidities, and Treatments
HUSAK, A., & Bair, M. J. (2019) · Pain Medicine · doi:10.1093/pm/pnz343 · Cited by 144 · see citing works
Associations between sleep disturbance and primary headaches: the third Nord-Trøndelag Health Study
Ødegård, S. S., Engstrøm, M., Sand, T., Stovner, L. J., Zwart, J., & Hagen, K. (2010) · The Journal of Headache and Pain · doi:10.1007/s10194-010-0201-8 · Cited by 144 · see citing works
Pain as a mediator of sleep problems in arthritis and other chronic conditions
Power, J. D., Perruccio, A. V., & Badley, E. M. (2005) · Arthritis Care & Research · doi:10.1002/art.21584 · Cited by 145 · see citing works
Increased sensitivity to physical activity among individuals with knee osteoarthritis: Relation to pain outcomes, psychological factors, and responses to quantitative sensory testing
Wideman, T. H., Finan, P. H., Edwards, R. R., Quartana, P. J., Buenaver, L. F., Haythornthwaite, J. A., & Smith, M. T. (2014) · Pain · doi:10.1016/j.pain.2013.12.028 · Cited by 142 · see citing works
Characteristics of Chronic Pain Associated with Sleep Difficulty in Older Adults: The Maintenance of Balance, Independent Living, Intellect, and Zest in the Elderly (MOBILIZE) Boston Study
Chen, Q., Hayman, L. L., Shmerling, R. H., Bean, J. F., & Leveille, S. G. (2011) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2011.03544.x · Cited by 140 · see citing works
Relationships Between Sleep Quality and Pain-Related Factors for People with Chronic Low Back Pain: Tests of Reciprocal and Time of Day Effects
Gerhart, J. I., Burns, J. W., Post, K. M., Smith, D. A., Porter, L. S., Burgess, H. J., Schuster, E., Buvanendran, A., Fras, A. M., & Keefe, F. J. (2016) · Annals of Behavioral Medicine · doi:10.1007/s12160-016-9860-2 · Cited by 137 · see citing works
Comparative effectiveness of CBT interventions for co-morbid chronic pain & insomnia: A pilot study
Pigeon, W. R., Moynihan, J., Matteson-Rusby, S., Jungquist, C. R., Xia, Y., Tu, X., & Perlis, M. L. (2012) · Behaviour Research and Therapy · doi:10.1016/j.brat.2012.07.005 · Cited by 134 · see citing works
Use and Costs of Prescription Medications and Alternative Treatments in Patients with Osteoarthritis and Chronic Low Back Pain in Community‐Based Settings
Gore, M. R., Tai, K., Sadosky, A., LESLIE, D. L., & Stacey, B. R. (2012) · Pain Practice · doi:10.1111/j.1533-2500.2012.00532.x · Cited by 138 · see citing works
The prevalence and risk factors of sleep disturbances in surgical patients: A systematic review and meta-analysis
Butris, N., Tang, E., Pivetta, B., He, D., Saripella, A., Yan, E., Englesakis, M. F., Boulos, M. I., Nagappa, M., & Chung, F. F. (2023) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2023.101786 · Cited by 145 · see citing works
The Relation of Trouble Sleeping, Depressed Mood, Pain, and Fatigue in Patients with Cancer
Stepanski, E. J., Walker, M. S., Schwartzberg, L. S., Blakely, L. J., Ong, J. C., & Houts, A. C. (2009) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.27441 · Cited by 134 · see citing works
Cognitive behavioral treatments for insomnia and pain in adults with comorbid chronic insomnia and fibromyalgia: clinical outcomes from the SPIN randomized controlled trial
McCrae, C. S., Williams, J. M., Roditi, D., Anderson, R., Mundt, J. M., Miller, M. B., Curtis, A. F., Waxenberg, L. B., Staud, R. M., Berry, R. B., et al. (2018) · SLEEP · doi:10.1093/sleep/zsy234 · Cited by 138 · see citing works
Sleep Quality and Functional Disability in Patients with Rheumatoid Arthritis
Luyster, F. S., Chasens, E. R., Wasko, M. C., & Dunbar‐Jacob, J. M. (2011) · Journal of Clinical Sleep Medicine · doi:10.5664/jcsm.28041 · Cited by 131 · see citing works
Sleep problems and pain
Bonvanie, I. J., Oldehinkel, A. J., Rosmalen, J. G. M., & Janssens, K. A. M. (2015) · Pain · doi:10.1097/j.pain.0000000000000466 · Cited by 131 · see citing works
Sleep disturbance, distress, and quality of life in ovarian cancer patients during the first year after diagnosis
Clevenger, L., Schrepf, A., DeGeest, K., Bender, D., Goodheart, M., Ahmed, A., Dahmoush, L., Penedo, F., Lucci, J., Thaker, P. H., et al. (2013) · Cancer · doi:10.1002/cncr.28188 · Cited by 127 · see citing works
“Bidirectional relationships may exist between chronic pain and sleep disturbance.(43) Specifically, chronic pain is thought to contribute to poorer sleep, which in turn may increase pain sensitivity.”
Background
Objective and subjective assessment of sleep in chronic low back pain patients compared with healthy age and gender matched controls: a pilot study
O’Donoghue, G., Fox, N. A., Heneghan, C., & Hurley, D. A. (2009) · BMC Musculoskeletal Disorders · doi:10.1186/1471-2474-10-122 · Cited by 127 · see citing works
Sleep disturbances and sleep disorders as risk factors for chronic postsurgical pain: A systematic review and meta-analysis
Varallo, G., Giusti, E. M., Manna, C., Castelnuovo, G., Pizza, F., Franceschini, C., & Plazzi, G. (2022) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2022.101630 · Cited by 127 · see citing works
Clinical comorbidities, treatment patterns, and direct medical costs of patients with osteoarthritis in usual care: a retrospective claims database analysis
Gore, M. R., Tai, K.-S., Sadosky, A., LESLIE, D. L., & Stacey, B. R. (2011) · Journal of Medical Economics · doi:10.3111/13696998.2011.594347 · Cited by 127 · see citing works
Prevalence of sleep deprivation in patients with chronic neck and back pain: a retrospective evaluation of 1016 patients
Artner, J., Çakır, B., Spiekermann, Kurz, Leucht, Reichel, & Lattig (2012) · Journal of Pain Research · doi:10.2147/jpr.s36386 · Cited by 125 · see citing works
Chronic pain patients' perspectives of medical cannabis
Piper, B. J., Beals, M. L., Abess, A. T., Nichols, S. D., Martin, M. W., Cobb, C. M., & DeKeuster, R. M. (2017) · Pain · doi:10.1097/j.pain.0000000000000899 · Cited by 124 · see citing works
Polysomnographic characteristics in nonmalignant chronic pain populations: A review of controlled studies
Bjurstrom, M. F., & Irwin, M. R. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.03.004 · Cited by 123 · see citing works
Insomnia, Sleep Duration, Depressive Symptoms, and the Onset of Chronic Multisite Musculoskeletal Pain
Generaal, E., Vogelzangs, N., Penninx, B. W. J. H., & Dekker, J. (2016) · SLEEP · doi:10.1093/sleep/zsw030 · Cited by 122 · see citing works
Concurrent Use of Alcohol and Sedatives Among Persons Prescribed Chronic Opioid Therapy: Prevalence and Risk Factors
Saunders, K. W., Korff, M. V., Campbell, C. I., Banta‐Green, C. J., Sullivan, M. D., Merrill, J. O., & Weisner, C. M. (2012) · Journal of Pain · doi:10.1016/j.jpain.2011.11.004 · Cited by 114 · see citing works
Intraindividual Variability in Daily Sleep and Pain Ratings Among Chronic Pain Patients
O’Brien, E. M., Waxenberg, L. B., Atchison, J. W., Gremillion, H. A., Staud, R. M., McCrae, C. S., & Robinson, M. E. (2011) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e318208c8e4 · Cited by 113 · see citing works
The Interface of Pain and Mood Disturbances in the Rheumatic Diseases
Goldenberg, D. L. (2009) · Seminars in Arthritis and Rheumatism · doi:10.1016/j.semarthrit.2008.11.005 · Cited by 112 · see citing works
Insomnia, sleep quality, pain, and somatic symptoms: Sex differences and shared genetic components
Zhang, J., Lam, S. P., Li, S. X., Tang, N. L. S., Yu, M., Li, A. M., & Wing, Y. K. (2012) · Pain · doi:10.1016/j.pain.2011.12.003 · Cited by 111 · see citing works
Sleep, Sleep Disorders, and Circadian Health following Mild Traumatic Brain Injury in Adults: Review and Research Agenda
Wickwire, E. M., Schnyer, D. M., Germain, A., Smith, M. T., Williams, S. G., Lettieri, C. J., McKeon, A. B., Scharf, S. M., Stocker, R., Albrecht, J. S., et al. (2018) · Journal of Neurotrauma · doi:10.1089/neu.2017.5243 · Cited by 106 · see citing works
Evidence for indirect effects of pain catastrophizing on clinical pain among myofascial temporomandibular disorder participants: The mediating role of sleep disturbance
Buenaver, L. F., Quartana, P. J., Grace, E. G., Sarlani, E., Simango, M., Edwards, R. R., Haythornthwaite, J. A., & Smith, M. T. (2012) · Pain · doi:10.1016/j.pain.2012.01.023 · Cited by 105 · see citing works
Chronic Low Back Pain, Sleep Disturbance, and Interleukin-6
Heffner, K. L., France, C. R., Trost, Z., Ng, H. M., & Pigeon, W. R. (2010) · Clinical Journal of Pain · doi:10.1097/ajp.0b013e3181eef761 · Cited by 108 · see citing works
A systematic review of the effects of acupuncture in treating insomnia
Huang, W., Kutner, N. G., & Bliwise, D. L. (2008) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2008.04.002 · Cited by 105 · see citing works
Rethinking chronic pain in a primary care setting
Stanos, S. P., Brodsky, M., Argoff, C. E., Clauw, D. J., D’Arcy, Y. M., Donevan, S. D., Gebke, K. B., Jensen, M. P., Clark, E. L., McCarberg, B. H., et al. (2016) · Postgraduate Medicine · doi:10.1080/00325481.2016.1188319 · Cited by 101 · see citing works
A Randomized Controlled Trial of Cognitive-behavioral Therapy for the Treatment of PTSD in the Context of Chronic Whiplash
Dunne, R. L., Kenardy, J., & Sterling, M. (2012) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e318243e16b · Cited by 103 · see citing works
Cebranopadol, a novel first-in-class analgesic drug candidate: first experience in patients with chronic low back pain in a randomized clinical trial
Christoph, A., Eerdekens, M., Kok, M., Volkers, G., & Freynhagen, R. (2017) · Pain · doi:10.1097/j.pain.0000000000000986 · Cited by 103 · see citing works
The relationship between sleep quality and fibromyalgia symptoms
Andrade, A., Vilarino, G. T., Sieczkowska, S. M., Coimbra, D. R., Bevilacqua, G. G., & Steffens, R. D. A. K. (2018) · Journal of Health Psychology · doi:10.1177/1359105317751615 · Cited by 108 · see citing works
Resilience moderates the association between chronic pain and depressive symptoms in the elderly
Bauer, H., Emeny, R. T., Baumert, J., & Ladwig, K. (2016) · European Journal of Pain · doi:10.1002/ejp.850 · Cited by 101 · see citing works
Sex differences in measures of central sensitization and pain sensitivity to experimental sleep disruption: implications for sex differences in chronic pain
Smith, M. T., Remeniuk, B., Finan, P. H., Speed, T. J., Tompkins, D. A., Robinson, M., Gonzalez, K., Bjurström, M. F., & Irwin, M. R. (2018) · SLEEP · doi:10.1093/sleep/zsy209 · Cited by 101 · see citing works
Medical and Psychological Risks and Consequences of Long-Term Opioid Therapy in Women
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Penedo, J. M. G., Rubel, J. A., Blättler, L., Schmidt, S. J., Stewart, J., Egloff, N., & Holtforth, M. G. (2019) · Clinical Journal of Pain · doi:10.1097/ajp.0000000000000797 · Cited by 100 · see citing works
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Long-term outcomes and predictors of chronic insomnia: a prospective study in Hong Kong Chinese adults.
Zhang, J.-H., Lam, S., Li, S., Yu, M. W., Li, A. M., Ma, R., Kong, A. P. S., & Wing, Y. K. (2012) · Sleep Medicine · doi:10.1016/j.sleep.2011.11.015 · Cited by 103 · see citing works
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Authors: Smith, M. T., & Haythornthwaite, J. A.
Affiliations: Johns Hopkins University (US)
Corresponding author: Smith, Michael T
ORCID: Smith, Michael T
Haythornthwaite, Jennifer A
Venue: Sleep Medicine Reviews
Publisher: Elsevier BV
Published: 2004-04
Volume: 8
Issue: 2
Pages: 119-132
ISSN: 1087-0792 (ISSN-L)
DOI: 10.1016/s1087-0792(03)00044-3
OpenAlex: W2167864730
Cited by: 914
References: 95
Citations by year: 2026: 38 · 2025: 44 · 2024: 33 · 2023: 52 · 2022: 54 · 2021: 61 · 2020: 59 · 2019: 58 · 2018: 55 · 2017: 58 · 2016: 64 · 2015: 64 · 2014: 52 · 2013: 33 · 2012: 41
FWCI: 2.54
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Sleep Medicine Reviews (publishedVersion)
PubMed (publishedVersion)
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
Keywords: sleep disorders, chronic pain, insomnia, cognitive behavioral therapy for insomnia, pain management, sleep quality, longitudinal study
MeSH terms: Chronic Disease, Clinical Trials as Topic, Humans, Pain, Sleep Wake Disorders, Cognitive Behavioral Therapy, Pain Management

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How do sleep disturbance and chronic pain inter-relate? Insights from the longitudinal and cognitive-behavioral clinical trials literature

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