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Searching for a photocycle of the cryptochrome photoreceptors

Open access
Liu, Bin, Liu, Hongtao, Zhong, Dongping, Lin, Chentao·2010·Current Opinion in Plant Biology

Abstract

The initial photochemistry of plant cryptochromes has been extensively investigated in recent years. It is hypothesized that cryptochrome photoexcitation involves a Trp-triad-dependent photoreduction. According to this hypothesis, cryptochromes in the resting state contain oxidized FAD; light triggers a sequential electron transfer from three tryptophan residues to reduce FAD to a neutral semiquinone (FADH•); FADH• is the presumed signaling state and it is re-oxidized to complete the photocycle. However, this photoreduction hypothesis is currently under debate. An alternative model argues that the initial photochemistry of cryptochromes involves a photolyase-like cyclic electron shuttle without a bona fide redox reaction mediated by the Trp-triad residues, leading to conformational changes, signal propagation, and physiological responses.

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Metadata

Authors
Liu, B., Liu, H., Zhong, D., & Lin, C.
Venue
Current Opinion in Plant Biology
Publisher
Elsevier BV
Published
2010-10
Volume
13
Issue
5
Pages
578-586
ISSN
1369-5266 (ISSN-L)
OpenAlex
W2048001052
Cited by
169
References
3
FWCI
10.91
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Searching for a photocycle of the cryptochrome photoreceptors. https://app.cochat.ai/papers/10.1016/j.pbi.2010.09.005
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Liu, B., Liu, H., Zhong, D., & Lin, C. (2010). Searching for a photocycle of the cryptochrome photoreceptors. Current Opinion in Plant Biology. https://doi.org/10.1016/j.pbi.2010.09.005

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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