The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
Magnetically sensitive light-induced reactions in cryptochrome are consistent with its proposed role as a magnetoreceptor
Open accessAbstract
Among the biological phenomena that fall within the emerging field of “quantum biology” is the suggestion that magnetically sensitive chemical reactions are responsible for the magnetic compass of migratory birds. It has been proposed that transient radical pairs are formed by photo-induced electron transfer reactions in cryptochrome proteins and that their coherent spin dynamics are influenced by the geomagnetic field leading to changes in the quantum yield of the signaling state of the protein. Despite a variety of supporting evidence, it is still not clear whether cryptochromes have the properties required to respond to magnetic interactions orders of magnitude weaker than the thermal energy, k B T . Here we demonstrate that the kinetics and quantum yields of photo-induced flavin—tryptophan radical pairs in cryptochrome are indeed magnetically sensitive. The mechanistic origin of the magnetic field effect is clarified, its dependence on the strength of the magnetic field measured, and the rates of relevant spin-dependent, spin-independent, and spin-decoherence processes determined. We argue that cryptochrome is fit for purpose as a chemical magnetoreceptor.
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Cites
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Self-citationA Model for Photoreceptor-Based Magnetoreception in Birds
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The cryptochromes: blue light photoreceptors in plants and animals
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Self-citationA pooled analysis of magnetic fields and childhood leukaemia
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Crystal Structure of DNA Photolyase from Escherichia coli
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Chemical magnetoreception in birds: The radical pair mechanism
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Self-citationA Pooled Analysis of Magnetic Fields, Wire Codes, and Childhood Leukemia
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Cryptochrome Blue Light Photoreceptors Are Activated through Interconversion of Flavin Redox States
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Cited by
Lambert, N., Chen, Y.-N., Cheng, Y.-C., Li, C.-M., Chen, G.-Y., & Nori, F. (2013) · Nature Physics · doi:10.1038/nphys2474 · Cited by 948
The Radical-Pair Mechanism of Magnetoreception
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Self-citationMagnetic field effects on plant growth, development, and evolution
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The quantum needle of the avian magnetic compass
Hiscock, H. G., Worster, S., Kattnig, D. R., Steers, C., Jin, Y., Manolopoulos, D. E., Mouritsen, H., & Hore, P. J. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1600341113 · Cited by 215
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Metadata
- Authors
- Maeda, K., Robinson, A. J., Henbest, K. B., Hogben, H. J., Biskup, T., Ahmad, M., Schleicher, E., Weber, S., Timmel, C. R., & Hore, P. J.
- Venue
- Proceedings of the National Academy of Sciences
- Published
- 2012-03-14
- Volume
- 109
- Issue
- 13
- Pages
- 4774-4779
- ISSN
- 0027-8424 (ISSN-L)
- 1091-6490
- OpenAlex
- W2065672538
- Cited by
- 373
- References
- 47
- FWCI
- 11.11
- Type
- journal article
- Language
- en
- Open access
- green
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- Maeda, K., Robinson, A. J., Henbest, K. B., Hogben, H. J., Biskup, T., Ahmad, M., Schleicher, E., Weber, S., Timmel, C. R., & Hore, P. J. (2012). Magnetically sensitive light-induced reactions in cryptochrome are consistent with its proposed role as a magnetoreceptor. Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1118959109
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