The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Human Milk Composition
Open accessAbstract
Synopsis The composition of human milk is the biologic norm for infant nutrition. Human milk also contains many hundreds to thousands of distinct bioactive molecules that protect against infection and inflammation and contribute to immune maturation, organ development, and healthy microbial colonization. Some of these molecules, e.g., lactoferrin, are being investigated as novel therapeutic agents. A dynamic, bioactive fluid, human milk changes in composition from colostrum to late lactation, and varies within feeds, diurnally, and between mothers. Feeding infants with expressed human milk is increasing. Pasteurized donor milk is now commonly provided to high risk infants and most mothers in the U.S. express and freeze their milk at some point in lactation for future infant feedings. Many milk proteins are degraded by heat treatment and freeze-thaw cycles may not have the same bioactivity after undergoing these treatments. This article provides an overview of the composition of human milk, sources of its variation, and its clinical relevance.
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Cites
Breastfeeding and the use of human milk
BREASTFEEDING, S. O., Eidelman, A. I., Schanler, R. J., Johnston, M., Landers, S., Noble, L., Szucs, K., & Viehmann, L. (2012) · Pediatrics · doi:10.1542/peds.2011-3552 · Cited by 4,357
Inhibition of cytomegalovirus infection by lactoferrin in vitro and in vivo
BELJAARS, L., VANDERSTRATE, B., BAKKER, H., REKERSMIT, C., VANLOENENWEEMAES, A., WIEGMANS, F., HARMSEN, M., MOLEMA, G., & MEIJER, D. (2004) · Antiviral Research · doi:10.1016/j.antiviral.2004.05.002 · Cited by 78
Cited by
Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., Buzas, E. I., Blenkiron, C., Bussolati, B., Cai, H., Di Vizio, D., Driedonks, T. A. P., Erdbrügger, U., et al. (2024) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12404 · Cited by 4,663
Breast milk, a source of beneficial microbes and associated benefits for infant health
Lyons, K. E., Ryan, C. A., Dempsey, E. M., Ross, R. P., & Stanton, C. (2020) · Nutrients · doi:10.3390/nu12041039 · Cited by 613
Breastfeeding and asthma and allergies: a systematic review and meta‐analysis
Lodge, C., Tan, D., Lau, M., Dai, X., Tham, R., Lowe, A., Bowatte, G., Allen, K., & Dharmage, S. (2015) · Acta Paediatrica · doi:10.1111/apa.13132 · Cited by 581
Mother’s Milk: A purposeful contribution to the development of the infant microbiota and immunity
Le Doare, K., Holder, B., Bassett, A., & Pannaraj, P. S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00361 · Cited by 475
Kell, D. B., Heyden, E. L., & Pretorius, E. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.01221 · Cited by 460
Metadata
- Authors
- Ballard, O., & Morrow, A. L.
- Venue
- Pediatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2013-02
- Volume
- 60
- Issue
- 1
- Pages
- 49-74
- ISSN
- 0031-3955 (ISSN-L)
- OpenAlex
- W204171329
- Cited by
- 2,598
- References
- 2
- FWCI
- 44.75
- Type
- journal article
- Language
- en
- Open access
- green
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