Heme as key regulator of major mammalian cellular functions: Molecular, cellular, and pharmacological aspects

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Cell Biology of Heme

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Bach Proteins Belong to a Novel Family of BTB-Basic Leucine Zipper Transcription Factors That Interact with MafK and Regulate Transcription through the NF-E2 Site

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Heme mediates derepression of Maf recognition element through direct binding to transcription repressor Bach1

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Hemoxygenase-2 Is an Oxygen Sensor for a Calcium-Sensitive Potassium Channel

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Identification of a Human Heme Exporter that Is Essential for Erythropoiesis

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Heme Protein Assemblies

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Control of globin gene expression during development and erythroid differentiation

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The enzymatic catabolism of hemoglobin: stimulation of microsomal heme oxygenase by hemin.

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Heme regulates the dynamic exchange of Bach1 and NF-E2-related factors in the Maf transcription factor network

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Heme oxygenase and the cardiovascular–renal system

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Reciprocal regulation of haem biosynthesis and the circadian clock in mammals

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Sequential induction of heme pathway enzymes during erythroid differentiation of mouse Friend leukemia virus-infected cells.

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Heme-based sensors: defining characteristics, recent developments, and regulatory hypotheses

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Heme oxygenase-1 gene ablation or expression modulates cisplatin-induced renal tubular apoptosis

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Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress

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A mutation in the human heme A:farnesyltransferase gene (COX10 ) causes cytochrome c oxidase deficiency

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Gene Therapy Strategy for Long-Term Myocardial Protection Using Adeno-Associated Virus-Mediated Delivery of Heme Oxygenase Gene

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Heme binds to a short sequence that serves a regulatory function in diverse proteins.

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Haem can bind to and inhibit mammalian calcium-dependent Slo1 BK channels

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Human SCO1 and SCO2 have independent, cooperative functions in copper delivery to cytochrome c oxidase

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Assembly of Cytochrome c Oxidase within the Mitochondrion

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Heme regulates gene expression by triggering Crm1‐dependent nuclear export of Bach1

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Induction of globin mRNA accumulation by hemin in cultured erythroleukemic cells

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Heme deficiency may be a factor in the mitochondrial and neuronal decay of aging

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Oxidases and Related Redox Systems

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Crystal structure of 5‐aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans

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Heme Degradation by Reactive Oxygen Species

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Dynamic changes in transcription factor complexes during erythroid differentiation revealed by quantitative proteomics

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Cytochrome oxidase in health and disease

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Structure–Function Relationships in Heme-Proteins

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Antiapoptotic role of heme oxygenase (HO) and the potential of HO as a target in anticancer treatment

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The structure of carbonmonoxy neuroglobin reveals a heme-sliding mechanism for control of ligand affinity

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Heme Deficiency Selectively Interrupts Assembly of Mitochondrial Complex IV in Human Fibroblasts

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Mechanisms involved in the induced differentiation of leukemia cells

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The Heme Oxygenase Dilemma in Cellular Homeostasis: New Insights for the Feedback Regulation of Heme Catabolism

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Angiotensin II induces apoptosis in renal proximal tubular cells

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Transcriptional Regulation of Globin Gene Expression in the Human Erythroid Cell Line K562

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Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation

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How Cytochromes with Different Folds Control Heme Redox Potentials

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Purification, characterization, and cloning of a heme-binding protein (23 kDa) in rat liver cytosol

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Hemin binding and oxidation of lipoproteins in serum: mechanisms and effect on the interaction of LDL with human macrophages

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Function of human cytochrome P450s: Characterization of the orphans

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Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis

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Apoptosis induced by erythroid differentiation of human leukemia cell lines is inhibited by Bcl-XL

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Induction of Hemoglobin Accumulation in Human K562 Cells by Hemin Is Reversible

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Heme Positively Regulates the Expression of β-Globin at the Locus Control Region via the Transcriptional Factor Bach1 in Erythroid Cells

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Heme: a determinant of life and death in renal tubular epithelial cells

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Crystal Structure of Human SCO1

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Molecular Characterization of a Newly Identified Heme-binding Protein Induced during Differentiation of urine Erythroleukemia Cells

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Hemin enhances the differentiation of mouse 3T3 cells to adipocytes

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The role of heme in gene expression.

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Aquisition, Mobilization and Utilization of Cellular Iron and Heme: Endless Findings and Growing Evidence of Tight Regulation

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