The DOI matches its Crossref record; 303 of the 303 references it cites were found in a registry or an index.
Cancer stem cells and chemoresistance: The smartest survives the raid
Open accessAbstract
Chemoresistant metastatic relapse of minimal residual disease plays a significant role for poor prognosis of cancer. Growing evidence supports a critical role of cancer stem cell (CSC) behind the mechanisms for this deadly disease. This review briefly introduces the basics of the conventional chemotherapies, updates the CSC theories, highlights the molecular and cellular mechanisms by which CSC smartly designs and utilizes multiple lines of self-defense to avoid being killed by chemotherapy, and concisely summarizes recent progress in studies on CSC-targeted therapies in the end, with the hope to help guide future research towards developing more effective therapeutic strategies to eradicate tumor cells in the patients.
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Cited by
Targeting cancer stem cell pathways for cancer therapy
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Cancer stem cells as key drivers of tumour progression
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The Role of Nrf2 Activity in Cancer Development and Progression
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Metadata
- Authors
- Zhao, J.
- Venue
- Pharmacology & Therapeutics
- Publisher
- Elsevier BV
- Published
- 2016-04
- Volume
- 160
- Pages
- 145-158
- ISSN
- 0163-7258 (ISSN-L)
- OpenAlex
- W2284683492
- Cited by
- 437
- References
- 303
- FWCI
- 20.86
- Type
- journal article
- Language
- en
- Open access
- green
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
