The neurobiology of depression, ketamine and rapid-acting antidepressants: Is it glutamate inhibition or activation?

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Chronic stress pathology and ketamine-induced alterations in functional connectivity in major depressive disorder: An abridged review of the clinical evidence

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The role of GPR39 zinc receptor in the modulation of glutamatergic and GABAergic transmission

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S-ketamine reduces marble burying behaviour: Involvement of ventromedial orbitofrontal cortex and AMPA receptors

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Study of the Neurotransmitter Changes Adjusted by Circadian Rhythm in Depression Based on Liver Transcriptomics and Correlation Analysis

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Ketamine and Zinc: Treatment of Anorexia Nervosa Via Dual NMDA Receptor Modulation

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Shared effects of electroconvulsive shocks and ketamine on neuroplasticity: A systematic review of animal models of depression

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NLRP3 inflammasome: structure, mechanism, drug-induced organ toxicity, therapeutic strategies, and future perspectives

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Measuring acute effects of subanesthetic ketamine on cerebrovascular hemodynamics in humans using TD-fNIRS

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Reelin Rescues Behavioral, Electrophysiological, and Molecular Metrics of a Chronic Stress Phenotype in a Similar Manner to Ketamine

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Lack of rapid antidepressant effects of Kir4.1 channel inhibitors in a chronic social defeat stress model: Comparison with (R)-ketamine

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Repeated, low-dose oral esketamine in patients with treatment-resistant depression: pilot study

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A Review of fMRI Affective Processing Paradigms Used in the Neurobiological Study of Posttraumatic Stress Disorder

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Role of group II metabotropic glutamate receptors in ketamine's antidepressant actions

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Changes in synaptic markers after administration of ketamine or psychedelics: a systematic scoping review

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The 5-HT1A receptor biased agonists, NLX-204 and NLX-101, like ketamine, elicit rapid-acting antidepressant activity in the rat chronic mild stress model via cortical mechanisms

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Neuronal glutamatergic changes and peripheral markers of cytoskeleton dynamics change synchronically 24 h after sub-anaesthetic dose of ketamine in healthy subjects

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Could ketamine be the answer to treating treatment‐resistant major depressive disorder?

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A neuroactive steroid with a therapeutically interesting constellation of actions at GABAA and NMDA receptors

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Molecular mechanisms underlying the N-methyl-d-aspartate receptor antagonists: Highlighting their potential for transdiagnostic therapeutics

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Stress, mental disorder and ketamine as a novel, rapid acting treatment

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Targeting the dysfunction of glutamate receptors for the development of novel antidepressants

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Metformin as a potential antidepressant: Mechanisms and therapeutic insights in depression

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Oral ketamine reduces the experience of stress in people with chronic suicidality

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DNA Methylation in Depression and Depressive-Like Phenotype: Biomarker or Target of Pharmacological Intervention?

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cAMP-dependent protein kinase signaling is required for (2R,6R)-hydroxynorketamine to potentiate hippocampal glutamatergic transmission

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Effects of ketamine and other rapidly acting antidepressants on hippocampal excitatory and inhibitory transmission

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(2R,6R)-hydroxynorketamine rapidly potentiates optically-evoked Schaffer collateral synaptic activity

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Challenges and rewards of in vivo synaptic density imaging, and its application to the study of depression

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Traxoprodil Produces Antidepressant-Like Behaviors in Chronic Unpredictable Mild Stress Mice through BDNF/ERK/CREB and AKT/FOXO/Bim Signaling Pathway

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S-Ketamine Improves Slow Wave Sleep and the Associated Changes in Serum Protein Among Gynecological Abdominal Surgery Patients: A Randomized Controlled Trial

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Urine metabolomic responses to aerobic and resistance training in rats under chronic unpredictable mild stress

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Glutamate Chemical Exchange Saturation Transfer Imaging and Functional Alterations of Hippocampus in Rat Depression Model: A Pilot Study

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Physiology, NMDA Receptor

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Neural Integro-Differential Equations

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A molecular perspective on mGluR5 regulation in the antidepressant effect of ketamine

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Association Between Anterior Cingulate Cortex Neurochemical Profile and Clinical Remission After Electroconvulsive Treatment in Major Depressive Disorder

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Blocking the ErbB pathway during adolescence affects the induction of anxiety-like behavior in young adult maternal immune activation offspring

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Insights into the neurobiology of suicidality: explicating the role of glutamatergic systems through the lens of ketamine

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Activation of σ1-Receptors by R-Ketamine May Enhance the Antidepressant Effect of S-Ketamine

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Advancing past ketamine: emerging glutamatergic compounds for the treatment of depression

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Ketamine normalizes high-gamma power in the anterior cingulate cortex in a rat chronic pain model

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The intersection of astrocytes and the endocannabinoid system in the lateral habenula: on the fast-track to novel rapid-acting antidepressants

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Towards an expanded neurocognitive account of ketamine’s rapid antidepressant effects

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Dysfunction of GluN3A subunit is involved in depression-like behaviors through synaptic deficits

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Region- and time- specific effects of ketamine on cerebral blood flow: a randomized controlled trial

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Hippocampal subfield volumes predict treatment response to oral ketamine in people with suicidality

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Planar cell polarity proteins mediate ketamine-induced restoration of glutamatergic synapses in prefrontal cortical neurons in a mouse model for chronic stress

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Early Astrocytic Dysfunction Is Associated with Mistuned Synapses as well as Anxiety and Depressive-Like Behavior in the App NL - F Mouse Model of Alzheimer’s Disease

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A single dose of ketamine cannot prevent protracted stress-induced anhedonia and neuroinflammation in rats

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Association between ketogenic diets and depression: A cross-sectional analysis of the NHANES 2005–2023 August

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Treatment-resistant depression and intranasal esketamine: Spanish consensus on theoretical aspects

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Biological embedding of early trauma: the role of higher prefrontal synaptic strength

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Highly sensitive determination of l -glutamic acid in pig serum with an enzyme-free molecularly imprinted polymer on a carbon-nanotube modified electrode

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Cortical Mechanisms Contributing to Ketamine-Induced Dissociation

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Oxidative Stress in Treatment-Resistant and Refractory Depression: A Hidden Therapeutic Target?

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I. Antidepressants and sexual behavior: Weekly ketamine injections increase sexual behavior initially in female and male rats

Guarraci, F. A., Ali, M. A., Gonzalez, C. M. F., Lucero, D., Clemons, L. W., Davis, L. K., Henneman, E. L., Odell, S. E., & Meerts, S. H. (2020) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2020.173039 · Cited by 7

Effects of nitrous oxide and ketamine on electrophysiological and molecular responses in the prefrontal cortex of mice: A comparative study

Rozov, S. V., Saarreharju, R., Khirug, S., Storvik, M., Rivera, C., & Rantamäki, T. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176426 · Cited by 6

Esketamine Nasal Spray for Treatment-Resistant Depression

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Recent approaches to target apoptosis in neurological disorders

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Neuroadaptation in neurodegenerative diseases: compensatory mechanisms and therapeutic approaches

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Functional activity and connectivity signatures of ketamine and lamotrigine during negative emotional processing: a double-blind randomized controlled fMRI study

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Exploring ketamine’s reinforcement, cue-induced reinstatement, and nucleus accumbens cFos activation in male and female long evans rats

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Neurobiological Mechanisms of Ketamine: Depression, Suicide, Trauma, and Chronic Stress Pathologies

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Preclinical toxicological study of prolonged exposure to ketamine as an antidepressant

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Long access to cocaine self‐administration dysregulates the glutamate synapse in the nucleus accumbens core of serotonin transporter knockout rats

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A unique case of very low‐dose subcutaneous ketamine use: Maintenance option of ketamine for treatment‐resistant depression

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Neural correlates of the late positive potential in relation to non-suicidal self-injury in depressed youth

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Role of Genetic and Epigenetic Biomarkers in Treatment-Resistant Depression: A Literature Review

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Bifunctional Modulation of NMDA and Opioid Receptors in Ketamine Reinforcement and Misuse: Implications for Substance Use Disorder Treatment

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Elevated neuron specific enolase levels in post-traumatic stress disorder

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The next psychoactive drugs: From imipramine to ketamine

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Subanesthetic ketamine alters EEG signal complexity: Implications for treatment stratification in depression

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Boosting the ventrolateral periaqueductal gray-ventral tegmental area pathway by disinhibition of group II mGluRs alleviates chronic restraint stress-induced depression-like behavior in mice

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Transcriptional Signatures of Mitochondrial Metabolism Predict Esketamine-Induced rACC Structural Changes in Adolescent Major Depression

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