Duman, Ronald S.

Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

Santarelli, L., Saxe, M., Gross, C., Surget, A., Battaglia, F., Dulawa, S., Weisstaub, N., Lee, J., Duman, R., Arancio, O., et al. (2003) · Science

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 4,321

A Neurotrophic Model for Stress-Related Mood Disorders

Duman, R. S., & Monteggia, L. M. (2006) · Biological Psychiatry

Treatment of Major DepressionNerve injury and regeneration

Cited by 3,375

Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus

Malberg, J. E., Eisch, A. J., Nestler, E. J., & Duman, R. S. (2000) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 3,111

mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists

Li, N., Lee, B., Liu, R.-J., Banasr, M., Dwyer, J. M., Iwata, M., Li, X.-Y., Aghajanian, G., & Duman, R. S. (2010) · Science

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 2,881

A molecular and cellular theory of depression

Duman, R. S. (1997) · Archives of General Psychiatry

Treatment of Major DepressionStress Responses and Cortisol

Cited by 2,129

Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms

Pittenger, C., & Duman, R. S. (2008) · Neuropsychopharmacology

Treatment of Major DepressionStress Responses and Cortisol

Cited by 1,795

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Duman, R. S., Aghajanian, G. K., Sanacora, G., & Krystal, J. H. (2016) · Nature Medicine

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1,750

Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression

Shirayama, Y., Chen, A. C.-H., Nakagawa, S., Russell, D. S., & Duman, R. S. (2002) · The Journal of Neuroscience

Treatment of Major DepressionNerve injury and regeneration

Cited by 1,654

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

Duman, R. S., & Aghajanian, G. K. (2012) · Science

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1,651

Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

Sen, S., Duman, R., & Sanacora, G. (2008) · Biological Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 1,232

Glutamate N-methyl-D-aspartate Receptor Antagonists Rapidly Reverse Behavioral and Synaptic Deficits Caused by Chronic Stress Exposure

Li, N., Liu, R.-J., Dwyer, J. M., Banasr, M., Lee, B., Son, H., Li, X.-Y., Aghajanian, G., & Duman, R. S. (2011) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1,082

Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments

Duman, R. S., Sanacora, G., & Krystal, J. H. (2019) · Neuron

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 1,026

IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress

Koo, J. W., & Duman, R. S. (2008) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 862

Cell Proliferation in Adult Hippocampus is Decreased by Inescapable Stress: Reversal by Fluoxetine Treatment

Malberg, J. E., & Duman, R. S. (2003) · Neuropsychopharmacology

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 815

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

Kang, H. J., Voleti, B., Hajszan, T., Rajkowska, G., Stockmeier, C. A., Licznerski, P., Lepack, A., Majik, M. S., Jeong, L. S., Banasr, M., et al. (2012) · Nature Medicine

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 808

Hippocampal neurogenesis: opposing effects of stress and antidepressant treatment

Warner‐Schmidt, J. L., & Duman, R. S. (2006) · Hippocampus

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 787

Regulation of cocaine reward by CREB

Carlezon, W. A., Thome, J., Olson, V. G., Lane-Ladd, S. B., Brodkin, E. S., Hiroi, N., Duman, R. S., Neve, R. L., & Nestler, E. J. (1998) · Science

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 767

Neuroplasticity in cognitive and psychological mechanisms of depression: an integrative model

Price, R. B., & Duman, R. (2020) · Molecular Psychiatry

Treatment of Major DepressionStress Responses and Cortisol

Cited by 739

Signaling pathways underlying the pathophysiology and treatment of depression: novel mechanisms for rapid-acting agents

Duman, R. S., & Voleti, B. (2012) · Trends in Neurosciences

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 714

Integrating neuroimmune systems in the neurobiology of depression

Wohleb, E. S., Franklin, T., Iwata, M., & Duman, R. S. (2016) · Nature Reviews Neuroscience

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 668

Neuronal plasticity and survival in mood disorders

Duman, R. S., Malberg, J., Nakagawa, S., & D’Sa, C. (2000) · Biological Psychiatry

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 652

Expression of the transcription factor ΔFosB in the brain controls sensitivity to cocaine

Kelz, M. B., Chen, J., Carlezon, W. A., Whisler, K., Gilden, L., Beckmann, A. M., Steffen, C., Zhang, Y.-J., Marotti, L., Self, D. W., et al. (1999) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 641

How do antidepressants work? New perspectives for refining future treatment approaches

Harmer, C. J., Duman, R. S., & Cowen, P. J. (2017) · The Lancet Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 616

Nuclear factor-κB is a critical mediator of stress-impaired neurogenesis and depressive behavior

Koo, J. W., Russo, S. J., Ferguson, D., Nestler, E. J., & Duman, R. S. (2010) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 607