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Prevention and management of idiosyncratic drug-induced liver injury: Systematic review and meta-analysis of randomised clinical trials

Niu, Hao, Sanabria-Cabrera, Judith, Alvarez-Alvarez, Ismael, Robles-Diaz, Mercedes, Stankevičiūtė, Simona, Aithal, Guruprasad P., Björnsson, Einar S., Andrade, Raul J., Lucena, M. Isabel·2021·Pharmacological Research

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  1. Robles-Diaz, 2014, Use of Hy’s law and a new composite algorithm to predict acute liver failure in patients with drug-induced liver injury, Gastroenterology, 147, 109, 10.1053/j.gastro.2014.03.050 · DOI · Paper page
  2. Mallat, 1997, Terbinafine-induced prolonged cholestasis with reduction of interlobular bile ducts, Dig. Dis. Sci., 42, 1486, 10.1023/A:1018870828038 · DOI
  3. Lheureux, 2009, Carnitine in the treatment of valproic acid-induced toxicity, Clin. Toxicol., 47, 101, 10.1080/15563650902752376 · DOI
  4. Katsinelos, 2000, Ursodeoxycholic acid (UDCA) for the treatment of amoxycillin-clavulanate potassium (Augmentin)-induced intra-hepatic cholestasis: report of two cases, Eur. J. Gastroenterol. Hepatol., 12, 365, 10.1097/00042737-200012030-00017 · DOI
  5. Wree, 2011, Steroid and ursodesoxycholic acid combination therapy in severe drug-induced liver injury, Digestion, 84, 54, 10.1159/000322298 · DOI
  6. Mohammed Saif, 2012, Hepatoprotective efficacy of ursodeoxycholic acid in pediatrics acute lymphoblastic leukemia, Pediatr. Hematol. Oncol., 29, 627, 10.3109/08880018.2012.713083 · DOI
  7. Hu, 2019, Corticosteroid therapy in drug-induced liver injury: pros and cons, J. Dig. Dis., 20, 122, 10.1111/1751-2980.12697 · DOI
  8. Karkhanis, 2014, Steroid use in acute liver failure, Hepatology, 59, 612, 10.1002/hep.26678 · DOI
  9. Keays, 1991, Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial, BMJ, 303, 1026, 10.1136/bmj.303.6809.1026 · DOI
  10. Lee, 2009, Intravenous N-acetylcysteine improves transplant-free survival in early stage non-acetaminophen acute liver failure, Gastroenterology, 137, 856, 10.1053/j.gastro.2009.06.006 · DOI · Paper page
  11. Kortsalioudaki, 2008, Safety and efficacy of N-acetylcysteine in children with non-acetaminophen-induced acute liver failure, Liver Transpl., 14, 25, 10.1002/lt.21246 · DOI
  12. Squires, 2013, Intravenous N-acetylcysteine in pediatric patients with nonacetaminophen acute liver failure: a placebo-controlled clinical trial, Hepatology, 57, 1542, 10.1002/hep.26001 · DOI · Paper page
  13. Borlak, 2018, N-acetylcysteine and prednisolone treatment improved serum biochemistries in suspected flupirtine cases of severe idiosyncratic liver injury, Liver Int., 38, 365, 10.1111/liv.13538 · DOI
  14. Li, 2015, The role of oxidative stress and antioxidants in liver diseases, Int. J. Mol. Sci., 16, 26087, 10.3390/ijms161125942 · DOI
  15. Chen, 2015, Drug-induced liver injury: interactions between drug properties and host factors, J. Hepatol., 63, 503, 10.1016/j.jhep.2015.04.016 · DOI
  16. Koido, 2020, Polygenic architecture informs potential vulnerability to drug-induced liver injury, Nat. Med., 26, 1541, 10.1038/s41591-020-1023-0 · DOI
  17. Singh, 2012, Protective effect of curcumin, silymarin and N-acetylcysteine on antitubercular drug-induced hepatotoxicity assessed in an in vitro model, Hum. Exp. Toxicol., 31, 788, 10.1177/0960327111433901 · DOI
  18. Wang, 2018, Protective effects of silymarin on triptolide-induced acute hepatotoxicity in rats, Mol. Med. Rep., 17, 789
  19. Liu, 2009, Bicyclol: a novel drug for treating chronic viral hepatitis B and C, Med. Chem., 5, 29, 10.2174/157340609787049316 · DOI
  20. Yang, 2017, The anti-inflammatory activity of licorice, a widely used Chinese herb, Pharm. Biol., 55, 5, 10.1080/13880209.2016.1225775 · DOI
  21. Moher, 1998, Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analyses?, Lancet, 352, 609, 10.1016/S0140-6736(98)01085-X · DOI · Paper page
  22. Kjaergard, 2001, Reported methodologic quality and discrepancies between large and small randomized trials in meta-analyses, Ann. Intern. Med., 135, 982, 10.7326/0003-4819-135-11-200112040-00010 · DOI
  23. Higgins, 2002, Quantifying heterogeneity in a meta-analysis, Stat. Med., 21, 1539, 10.1002/sim.1186 · DOI · Paper page
  24. Egger, 1997, Bias in meta-analysis detected by a simple, graphical test, BMJ, 315, 629, 10.1136/bmj.315.7109.629 · DOI · Paper page
  25. Li, 2014, Role of bicyclol in preventing chemotherapeutic agent-induced liver injury in patients over 60 years of age with cancer, J. Int. Med. Res., 42, 906, 10.1177/0300060514527058 · DOI
  26. Chu, 2015, Role of bicyclol in preventing drug-induced liver injury in tuberculosis patients with liver disease, Int. J. Tuberc. Lung Dis., 19, 475, 10.5588/ijtld.14.0579 · DOI
  27. Hatamkhani, 2014, Carnitine for prevention of antituberculosis drug-induced hepatotoxicity: a randomized, clinical trial, J. Gastroenterol. Hepatol., 29, 997, 10.1111/jgh.12474 · DOI
  28. Yan, 2015, [Magnesium isoglycyrrhizinate prevention of chemotherapy-induced liver damage during initial treatment of patients with gastrointestinal tumors], Chin. J. Hepatol., 23, 204
  29. Baniasadi, 2010, Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity, Eur. J. Gastroenterol. Hepatol., 22, 1235, 10.1097/MEG.0b013e32833aa11b · DOI
  30. Gu, 2015, An open-label, randomized and multi-center clinical trial to evaluate the efficacy of silibinin in preventing drug-induced liver injury, Int. J. Clin. Exp. Med., 8, 4320
  31. Luangchosiri, 2015, A double-blinded randomized controlled trial of silymarin for the prevention of antituberculosis drug-induced liver injury, BMC Complement. Altern. Med., 15, 334, 10.1186/s12906-015-0861-7 · DOI
  32. Marjani, 2016, Evaluation of hepatoprotective effect of silymarin among under treatment tuberculosis patients: a randomized clinical trial, Iran. J. Pharm. Res., 15, 247
  33. Zhang, 2016, Preventive use of a hepatoprotectant against anti-tuberculosis drug-induced liver injury: a randomized controlled trial, J. Gastroenterol. Hepatol., 31, 409, 10.1111/jgh.13070 · DOI
  34. Heo, 2017, Effect of prophylactic use of silymarin on anti-tuberculosis drugs induced hepatotoxicity, Tuberc. Respir. Dis. (Seoul), 80, 265, 10.4046/trd.2017.80.3.265 · DOI
  35. Wu, 2017, [Efficacy of silibinin capsules in the prevention of liver injury induced by anti-tuberculosis drugs], Chin. J. Antituberc, 39, 757
  36. Li, 2014, The role of tiopronin for the prevention of chemotherapy-related liver toxicity in advanced colorectal cancer patients treated with mFOLFOX7: a prospective analysis, Tumori, 100, 446, 10.1177/1636.17908 · DOI
  37. Tang, 2013, [Analysis of the efficacy of bicyclol tablets in the treatment of liver injury caused by anti-tuberculosis drug], Xinxueguanbing Fangzhi Zhishi, 10, 83
  38. Wu, 2017, A multicenter and randomized controlled trial of bicyclol in the treatment of statin-induced liver injury, Med. Sci. Monit., 23, 5760, 10.12659/MSM.904090 · DOI
  39. Tang, 2012, [Magnesium isoglycyrrhizinate used in the treatment of chemotherapeutic drugs-induced acute liver dysfunction: a phase Ⅲ clinical trial], Tumor, 32, 738
  40. Wang, 2019, Efficacy and safety of magnesium isoglycyrrhizinate injection in patients with acute drug-induced liver injury: a phase II trial, Liver Int., 39, 2102, 10.1111/liv.14204 · DOI · Paper page
  41. Asgarshirazi, 2017, Comparison of efficacy of folic acid and silymarin in the management of antiepileptic drug induced liver injury: a randomized clinical trial, Hepatobiliary Pancreat. Dis. Int., 16, 296, 10.1016/S1499-3872(16)60142-X · DOI
  42. Marjani, 2019, Evaluation of silymarin for management of anti-tuberculosis drug induced liver injury: a randomized clinical trial, Gastroenterol. Hepatol. Bed Bench, 12, 138
  43. Zhou, 2018, [Clinical study on Yinzhihuang oral liquid combined with tiopronin in treatment of drug-induced liver injury], Drugs & Clinic, 33, 866
  44. Yuan, 2019, [Clinical study on Xuebijing injection combined with magnesium isoglycyrrhizinate in treatment of drug-induced liver injury], Drugs & Clinic, 34, 3102
  45. Nabi, 2017, Role of N-acetylcysteine treatment in non-acetaminophen-induced acute liver failure: a prospective study, Saudi J. Gastroenterol., 23, 169, 10.4103/1319-3767.207711 · DOI
  46. Drug-induced Liver Disease Study Group, 2015, [Guidelines for the management of drug-induced liver injury], J. Clin. Hepatol., 31, 1752
  47. Aithal, 2011, Case definition and phenotype standardization in drug-induced liver injury, Clin. Pharmacol. Ther., 89, 806, 10.1038/clpt.2011.58 · DOI
  48. Low, 2020, Drug induced liver injury: east versus West - a systematic review and meta-analysis, Clin. Mol. Hepatol., 26, 142, 10.3350/cmh.2019.1003 · DOI · Paper page
  49. Flora, 1998, Milk thistle (Silybum marianum) for the therapy of liver disease, Am. J. Gastroenterol., 93, 139, 10.1111/j.1572-0241.1998.00139.x · DOI
  50. Eminzade, 2008, Silymarin protects liver against toxic effects of anti-tuberculosis drugs in experimental animals, Nutr. Metab. (Lond.), 5, 18, 10.1186/1743-7075-5-18 · DOI
  51. Gillessen, 2020, Silymarin as supportive treatment in liver diseases: a narrative review, Adv. Ther., 37, 1279, 10.1007/s12325-020-01251-y · DOI
  52. Ramappa, 2013, Hepatotoxicity related to anti-tuberculosis drugs: mechanisms and management, J. Clin. Exp. Hepatol., 3, 37, 10.1016/j.jceh.2012.12.001 · DOI
  53. Lee, 2016, Early monitoring for detection of antituberculous drug-induced hepatotoxicity, Korean J. Intern. Med., 31, 65, 10.3904/kjim.2016.31.1.65 · DOI
  54. Abbara, 2017, Drug-induced liver injury from antituberculous treatment: a retrospective study from a large TB centre in the UK, BMC Infect. Dis., 17, 231, 10.1186/s12879-017-2330-z · DOI · Paper page
  55. Tao, 2019, Prophylactic therapy of silymarin (milk thistle) on antituberculosis drug-induced liver injury: a meta-analysis of randomized controlled trials, Can. J. Gastroenterol. Hepatol., 2019, 3192351, 10.1155/2019/3192351 · DOI
  56. Rambaldi, 2005, Milk thistle for alcoholic and/or hepatitis B or C liver diseases—a systematic cochrane hepato-biliary group review with meta-analyses of randomized clinical trials, Am. J. Gastroenterol., 100, 2583, 10.1111/j.1572-0241.2005.00262.x · DOI
  57. Yu, 2017, CSH guidelines for the diagnosis and treatment of drug-induced liver injury, Hepatol. Int., 11, 221, 10.1007/s12072-017-9793-2 · DOI
  58. Liu, 2005, Mechanism of protective action of bicyclol against CCl-induced liver injury in mice, Liver Int., 25, 872, 10.1111/j.1478-3231.2005.01103.x · DOI
  59. Wang, 2006, Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice, Eur. J. Pharmacol., 534, 194, 10.1016/j.ejphar.2005.12.080 · DOI
  60. Liu, 2017, Protective effect of bicyclol on anti-tuberculosis drug induced liver injury in rats, Molecules, 22, 524, 10.3390/molecules22040524 · DOI
  61. Zhao, 2020, Bicyclol attenuates acute liver injury by activating autophagy, anti-oxidative and anti-inflammatory capabilities in mice, Front. Pharmacol., 11, 463, 10.3389/fphar.2020.00463 · DOI
  62. Huang, 2014, [Pharmacoeconomic profiles of four hepatoprotective drugs used for the treatment of drug-induced liver injury], Chin. J. Hepatol., 22, 763
  63. Chalasani, 2014, ACG clinical guideline: the diagnosis and management of idiosyncratic drug-induced liver injury, Am. J. Gastroenterol., 109, 950, 10.1038/ajg.2014.131 · DOI · Paper page
  64. Xie, 2015, Anti-inflammatory activity of magnesium isoglycyrrhizinate through inhibition of phospholipase A2/arachidonic acid pathway, Inflammation, 38, 1639, 10.1007/s10753-015-0140-2 · DOI
  65. Jiang, 2017, Magnesium isoglycyrrhizinate shows hepatoprotective effects in a cyclophosphamide-induced model of hepatic injury, Oncotarget, 8, 33252, 10.18632/oncotarget.16629 · DOI
  66. Cao, 2019, Protective effects of magnesium glycyrrhizinate on methotrexate-induced hepatotoxicity and intestinal toxicity may be by reducing COX-2, Front. Pharmacol., 10, 119, 10.3389/fphar.2019.00119 · DOI
  67. Hu, 2015, Efficacy and safety of acetylcysteine in "non-acetaminophen" acute liver failure: a meta-analysis of prospective clinical trials, Clin. Res. Hepatol. Gastroenterol., 39, 594, 10.1016/j.clinre.2015.01.003 · DOI
  68. Elliott, 2016, Resolution of norfloxacin-induced acute liver failure after N-acetylcysteine therapy: further support for the use of NAC in drug-induced ALF?, BMJ Case Rep., 2016, 10.1136/bcr-2015-213189 · DOI
  69. Chughlay, 2016, N-Acetylcysteine for non-paracetamol drug-induced liver injury: a systematic review, Br. J. Clin. Pharmacol., 81, 1021, 10.1111/bcp.12880 · DOI
  70. Reuben, 2016, Outcomes in adults with acute liver failure between 1998 and 2013: an observational cohort study, Ann. Intern. Med., 164, 724, 10.7326/M15-2211 · DOI · Paper page
  71. Peeraphatdit, 2020, Hepatotoxicity from immune checkpoint inhibitors: a systematic review and management recommendation, Hepatology, 72, 315, 10.1002/hep.31227 · DOI · Paper page
  72. Watkins, 2008, Using controlled clinical trials to learn more about acute drug-induced liver injury, Hepatology, 48, 1680, 10.1002/hep.22633 · DOI
  73. Danan, 1993, Causality assessment of adverse reactions to drugs—I. A novel method based on the conclusions of international consensus meetings: application to drug-induced liver injuries, J. Clin. Epidemiol., 46, 1323, 10.1016/0895-4356(93)90101-6 · DOI · Paper page
  74. García-Cortés, 2011, Causality assessment methods in drug induced liver injury: strengths and weaknesses, J. Hepatol., 55, 683, 10.1016/j.jhep.2011.02.007 · DOI · Paper page

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Metadata

Authors
Niu, H., Sanabria-Cabrera, J., Alvarez-Alvarez, I., Robles-Diaz, M., Stankevičiūtė, S., Aithal, G. P., Björnsson, E. S., Andrade, R. J., & Lucena, M. I.
Venue
Pharmacological Research
Publisher
Elsevier BV
Published
2021-02
Volume
164
Pages
105404
ISSN
1043-6618
Cited by
58
References
4
Language
en
Funders
  • European Cooperation in Science and Technology (CA17112)
  • Instituto de Salud Carlos III (CM17/00243, CD20/00083, JR16/00015, PT17/0017/0020, PI18/01804, PI18/00901, PT 20/00127, B-0002-2019)
  • Federación Española de Enfermedades Raras
  • Consejería de Salud y Familias, Junta de Andalucía
  • European Regional Development Fund

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