The DOI matches its Crossref record; 60 of the 62 references it cites were found in a registry or an index.
Acetylcholinesterase inhibitors from plants
Abstract
Inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown of acetylcholine, is considered as a promising strategy for the treatment of neurological disorders such as Alzheimer's disease, senile dementia, ataxia and myasthenia gravis. A potential source of AChE inhibitors is certainly provided by the abundance of plants in nature. This article aims to provide a comprehensive literature survey of plants that have been tested for AChE inhibitory activity. Numerous phytoconstituents and promising plant species as AChE inhibitors are being reported in this communication.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“The secondary metabolites of the various classes such as alkaloids, terpenoids, coumarins, flavonoids, etc. have been reported to have potent AChEinhibitory activity [71,72,73,74].”
From Acetylcholinesterase Inhibitory Potential of Various Sesquiterpene Analogues for Alzheimer’s Disease Therapy (2021) · cites this paper as [73]
Citations
Cites
A new and rapid colorimetric determination of acetylcholinesterase activity
Ellman, G. L., Courtney, K. D., Andres, V., & Featherstone, R. M. (1961) · Biochemical Pharmacology · doi:10.1016/0006-2952(61)90145-9 · Cited by 27,221
SELECTIVE LOSS OF CENTRAL CHOLINERGIC NEURONS IN ALZHEIMER'S DISEASE
DAVIES, P. (1976) · The Lancet · doi:10.1016/s0140-6736(76)91936-x · Cited by 3,565
Asher, R. (1961) · The Lancet · doi:10.1016/s0140-6736(61)91217-x · Cited by 1,293
Erkinjuntti, T., Kurz, A., Gauthier, S., Bullock, R., Lilienfeld, S., & Damaraju, C. V. (2002) · The Lancet · doi:10.1016/s0140-6736(02)08267-3 · Cited by 752
Principles of Medicinal Chemistry
Delgado, J. N. (1975) · Journal of Pharmaceutical Sciences · doi:10.1002/jps.2600641047 · Cited by 723
Principles of medicinal chemistry
Foye, W. O. (1974) · Cited by 476
Rhee, I. K., van de Meent, M. H. M., Ingkaninan, K., & Verpoorte, R. (2001) · Journal of Chromatography A · doi:10.1016/s0021-9673(01)00624-0 · Cited by 465
Perry, N. S. L., Houghton, P. J., Theobald, A. E., Jenner, P. G., & Perry, E. K. (2000) · Journal of Pharmacy and Pharmacology · doi:10.1211/0022357001774598 · Cited by 458
Self-citationHowes, M. R., & Houghton, P. J. (2003) · Pharmacology Biochemistry and Behavior · doi:10.1016/s0091-3057(03)00128-x · Cited by 443
Self-citationPresynaptic Cholinergic Dysfunction in Patients with Dementia
Sims, N. R., Bowen, D. M., Allen, S. J., Smith, C., Neary, D., Thomas, D. J., & DAVISON, A. N. (1983) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1983.tb11311.x · Cited by 421
Cited by
Sorted by citations
Items 101–104 of 104
Dall'Acqua, S., Maggi, F., Minesso, P., Salvagno, M., Papa, F., Vittori, S., & Innocenti, G. (2010) · Fitoterapia · doi:10.1016/j.fitote.2010.08.003 · Cited by 63
Gul, R., Jan, H., Lalay, G., Andleeb, A., Usman, H., Zainab, R., Qamar, Z., Hano, C., & Abbasi, B. H. (2021) · Coatings · doi:10.3390/coatings11060717 · Cited by 33
Alarcón, J., Cespedes, C. L., Muñoz, E., Balbontin, C., Valdes, F., Gutierrez, M., Astudillo, L., & Seigler, D. S. (2015) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5b04168 · Cited by 33
Black soybean extract protects against TMT-induced cognitive defects in mice
Jeong, J. H., Jo, Y. N., Kim, H. J., Jin, D. E., Kim, D.-O., & Heo, H. J. (2014) · Journal of Medicinal Food · doi:10.1089/jmf.2013.3023 · Cited by 11
Metadata
- Authors
- Mukherjee, P. K., Kumar, V., Mal, M., & Houghton, P. J.
- Affiliations
- Jadavpur University (IN)
- King's College London (GB)
- Corresponding author
- Mukherjee, Pulok K.
- Venue
- Phytomedicine
- Publisher
- Elsevier BV
- Published
- 2007-04
- Volume
- 14
- Issue
- 4
- Pages
- 289-300
- ISSN
- 0944-7113 (ISSN-L)
- OpenAlex
- W2060288971
- Cited by
- 809
- References
- 62
- Citations by year
- 2026: 19 · 2025: 38 · 2024: 45 · 2023: 55 · 2022: 56 · 2021: 50 · 2020: 59 · 2019: 44 · 2018: 51 · 2017: 54 · 2016: 61 · 2015: 56 · 2014: 50 · 2013: 35 · 2012: 41
- FWCI
- 14.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Phytomedicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology (medical) › Cholinesterase and Neurodegenerative Diseases
- Health Sciences › Medicine › Complementary and alternative medicine › Medicinal Plants and Neuroprotection
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Drug Discovery › Bioactive natural compounds
- Keywords
- acetylcholinesterase inhibitors, phytochemicals, phytochemical constituents, Alzheimer's disease, senile dementia, myasthenia gravis, ataxia, acetylcholine, plant species screening
- MeSH terms
- Alzheimer Disease, Cholinesterase Inhibitors, Humans, Phytotherapy, Plant Extracts, Plants, Medicinal
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
