Treatment targets of exercise for persistent non-specific low back pain: a consensus study
Open accessAbstract
Objectives Despite several hundred previous randomised controlled trials (RCTs), the key treatment targets of exercise for persistent non-specific low back pain (NSLBP) remain unclear. This study aimed to generate consensus about the key treatment targets of exercise interventions for patients with NSLBP.Design Consensus was generated using modified nominal group technique in two, sequential, workshops. The results of a previous systematic review informed the first, national, workshop idea generation and the results of this workshop informed the second, international, workshop. The authors generated a starting list of 30 treatment targets from the systematic review. A pre-specified consensus threshold of 75% was used in the voting stage.Participants Workshop participants included people with experience of using exercise to manage their persistent NSLBP, clinicians who prescribe exercise for persistent NSLBP, and researchers who design and evaluate exercise interventions in RCTs. All participants generated, voted and ranked the treatment targets in each workshop using an online platform.Results A total of 39 participants contributed to the consensus (15 in the national workshop and 24 in the international workshop), comprising two people with NSLBP, six clinicians and 31 researchers/clinicians. A total of 40 exercise treatment targets were generated, and 25 were retained after voting and ranking. The prioritised targets of exercise for persistent NSLBP were: improving function, improving quality of life, reducing pain, meeting patient-specific goals and reducing fear of movement.Conclusions Future RCTs of exercise should specify the targets of their exercise intervention and consider assessing these treatment targets as well as including mediation analyses.
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The clinical outcomes assessed are consistent with consensus based treatment targets of exercise for people with chronic, non-specific low back pain.
“These clinical outcomes are also consistent with the consensus based treatment targets of exercise for people with chronic, non-specific LBP: to improve function, improve quality of life, reduce pain, meet patient specific goals, and reduce fear of movement.104”
From Psychological interventions for chronic, non-specific low back pain: systematic review with network meta-analysis (2022) · cites this paper as [104]
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Cites
Prevention and treatment of low back pain: evidence, challenges, and promising directions
Foster, N. E., Anema, J. R., Cherkin, D., Chou, R., Cohen, S. P., Gross, D. P., Ferreira, P. H., Fritz, J. M., Koes, B. W., Peul, W., et al. (2018) · The Lancet · doi:10.1016/s0140-6736(18)30489-6 · Cited by 2,398 · see citing works
Self-citationThe Cochrane Database of Systematic Reviews
Handoll, H. H. (2004) · The British Journal of Hand Therapy · doi:10.1177/175899830400900201 · Cited by 1,516 · see citing works
Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews
Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A., & Smith, B. H. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011279.pub3 · Cited by 1,222 · see citing works
Exercise therapy for treatment of non-specific low back pain
Hayden, J., van Tulder, M. W., Malmivaara, A., & Koes, B. W. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd000335.pub2 · Cited by 879 · see citing works
Self-citationHayden, J. A., van Tulder, M. W., & TOMLINSON, G. A. (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-9-200505030-00014 · Cited by 848 · see citing works
Self-citationNominal group technique: An effective method for obtaining group consensus
Harvey, N., & Holmes, C. A. (2012) · International Journal of Nursing Practice · doi:10.1111/j.1440-172x.2012.02017.x · Cited by 813 · see citing works
Physical activity and exercise for chronic pain in adults: an overview of Cochrane Reviews
Geneen, L. J., Moore, R. A., Clarke, C., Martin, D., Colvin, L. A., & Smith, B. H. (2017) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd011279.pub2 · Cited by 719 · see citing works
Stochkendahl, M. J., Kjær, P., Hartvigsen, J., Kongsted, A., Aaboe, J., Andersen, M., Andersen, M. Ø., Fournier, G. L., Højgaard, B., Jensen, M. B., et al. (2017) · European Spine Journal · doi:10.1007/s00586-017-5099-2 · Cited by 664 · see citing works
Exercise Interventions for Mental Health: A Quantitative and Qualitative Review.
Stathopoulou, G., Powers, M. B., Berry, A. C., Smits, J. A. J., & Otto, M. W. (2006) · Clinical Psychology: Science and Practice · doi:10.1111/j.1468-2850.2006.00021.x · Cited by 663 · see citing works
Searle, A., Spink, M., Ho, A., & Chuter, V. (2015) · Clinical Rehabilitation · doi:10.1177/0269215515570379 · Cited by 555 · see citing works
Lee, H., Hübscher, M., Moseley, G. L., Kamper, S. J., Traeger, A. C., Mansell, G., & McAuley, J. H. (2015) · Pain · doi:10.1097/j.pain.0000000000000146 · Cited by 526 · see citing works
Exercise therapy improves both mental and physical health in patients with major depression
Knapen, J., Vancampfort, D., Moriën, Y., & Marchal, Y. (2015) · Disability and Rehabilitation · doi:10.3109/09638288.2014.972579 · Cited by 395 · see citing works
Babatunde, O. O., Jordan, J. L., van der Windt, D., Hill, J. C., Foster, N. E., & Protheroe, J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0178621 · Cited by 390 · see citing works
Self-citationCefalu, W. T., Kaul, S., Gerstein, H. C., Holman, R. R., Zinman, B., Skyler, J. S., Green, J. B., Buse, J. B., Inzucchi, S. E., Leiter, L. A., et al. (2017) · Diabetes Care · doi:10.2337/dci17-0057 · Cited by 382 · see citing works
Exercise as a treatment for chronic low back pain
Rainville, J., Hartigan, C., Martinez, E., Limke, J. C., Jouve, C., & Finno, M. (2004) · The Spine Journal · doi:10.1016/s1529-9430(03)00174-8 · Cited by 337 · see citing works
Qualitative Research in Health Care
Webster, J. A. (2005) · Nursing Older People · doi:10.7748/nop.16.10.43.s21 · Cited by 335 · see citing works
Costal, L. D. C. M., Maherl, C. G., McAuleyl, J. H., Hancockl, M. J., & Smeetsl, R. J. E. M. (2011) · European Journal of Pain · doi:10.1016/j.ejpain.2010.06.014 · Cited by 312 · see citing works
Woby, S., Watson, P., Roach, N., & Urmston, M. (2004) · European Journal of Pain · doi:10.1016/j.ejpain.2003.08.002 · Cited by 264 · see citing works
Marshall, P. W., Schabrun, S. M., & Knox, M. F. (2017) · PLoS ONE · doi:10.1371/journal.pone.0180788 · Cited by 231 · see citing works
Cooney, G., Dwan, K., & Mead, G. (2014) · JAMA · doi:10.1001/jama.2014.4930 · Cited by 168 · see citing works
Musculoskeletal pain and exercise—Challenging existing paradigms and introducing new
Smith, B. E., Hendrick, P., Bateman, M., Holden, S., Littlewood, C., Smith, T. O., & Logan, P. (2019) · British Journal of Sports Medicine · doi:10.1136/bjsports-2017-098983 · Cited by 166 · see citing works
Water First Aid Is Beneficial In Humans Post-Burn: Evidence from a Bi-National Cohort Study
Wood, F. M., Phillips, M. R., Jovic, T., Cassidy, J. T., Cameron, P. A., & Edgar, D. W. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147259 · Cited by 159 · see citing works
The Nominal Group Technique: A useful concensus methodology in physiotherapy research
Potter, M., Gordon, S., & HAMER, P. W. (2004) · UWA Profiles and Research Repository (University of Western Australia) · Cited by 153 · see citing works
Rohwer, A., Pfadenhauer, L., Burns, J., Brereton, L., Gerhardus, A., Booth, A., Oortwijn, W., & Rehfuess, E. (2017) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2016.06.012 · Cited by 121 · see citing works
Individualized Exercise Interventions for Spinal Pain
Falla, D., & Hodges, P. W. (2017) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000103 · Cited by 116 · see citing works
Hurley, D. A., Murphy, L. C., Hayes, D., Hall, A. M., Toomey, E., McDonough, S. M., Lonsdale, C., Walsh, N. E., Guerin, S., & Matthews, J. (2015) · Implementation Science · doi:10.1186/s13012-016-0418-2 · Cited by 110 · see citing works
Moffett, J. K., Jackson, D. A., Gardiner, E., Torgerson, D. J., Coulton, S., Eaton, S., Mooney, M. P., Pickering, C., Green, A. J., Walker, L. G., et al. (2006) · Rheumatology · doi:10.1093/rheumatology/kel339 · Cited by 88 · see citing works
Why and how back pain interventions work: What can we do to find out?
Mansell, G., Kamper, S. J., & Kent, P. M. (2013) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2013.10.001 · Cited by 82 · see citing works
Garcia, A. N., Costa, L. D. C. M., Hancock, M. J., Souza, F. S. D., Gomes, G. V. F. D. O., Almeida, M. O. D., & Costa, L. O. P. (2018) · British Journal of Sports Medicine · doi:10.1136/bjsports-2016-097327 · Cited by 73 · see citing works
Causal mechanisms in the clinical course and treatment of back pain
Lee, H., Mansell, G., McAuley, J. H., Kamper, S. J., Hübscher, M., Moseley, G. L., Wolfenden, L., Hodder, R. K., & Williams, C. M. (2016) · Best Practice & Research Clinical Rheumatology · doi:10.1016/j.berh.2017.04.001 · Cited by 69 · see citing works
Froud, R., Patel, S., Rajendran, D., Bright, P., Bjørkli, T., Buchbinder, R., Eldridge, S. M., & Underwood, M. R. (2016) · PLoS ONE · doi:10.1371/journal.pone.0164573 · Cited by 66 · see citing works
Whittle, R., Mansell, G., Jellema, P., & van der Windt, D. (2016) · European Journal of Pain · doi:10.1002/ejp.964 · Cited by 55 · see citing works
Kong, A. P. S., Yang, X., Ko, G. T. C., So, W., Chan, W. B., Ronald, C. W., Ng, V., Chow, C., Cockram, C. S., Tong, P. C. Y., et al. (2007) · Diabetes Care · doi:10.2337/dc06-2443 · Cited by 50 · see citing works
Mansell, G., Hill, J. C., Main, C. J., Vowles, K. E., & van der Windt, D. (2016) · Journal of Pain · doi:10.1016/j.jpain.2016.08.005 · Cited by 50 · see citing works
Stevens, M. L., Boyle, E., Hartvigsen, J., Mansell, G., Søgaard, K., Jørgensen, M. B., Holtermann, A., & Rasmussen, C. D. N. (2018) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-018-1350-3 · Cited by 42 · see citing works
Black, N. A. (2006) · doi:10.1002/9780470750841.ch12 · Cited by 37 · see citing works
Exercise Therapy and Low Back Pain
Helmhout, P. H., Staal, J. B., Maher, C. G., Petersen, T., Rainville, J., & Shaw, W. S. (2008) · Spine · doi:10.1097/brs.0b013e31817b8fd6 · Cited by 34 · see citing works
McSharry, J., Fredrix, M., Hynes, L., & Byrne, M. (2016) · Research Involvement and Engagement · doi:10.1186/s40900-016-0028-9 · Cited by 33 · see citing works
Wood, L., Foster, N. E., Lewis, M., & Bishop, A. (2020) · Journal of Pain · doi:10.1016/j.jpain.2020.04.002 · Cited by 29 · see citing works
Self-citationGianola, S., Frigerio, P., Agostini, M., Bolotta, R., Castellini, G., Corbetta, D., Gasparini, M., Gozzer, P., Guariento, E., LI, L. C., et al. (2016) · Physiotherapy Canada · doi:10.3138/ptc.2015-30 · Cited by 26 · see citing works
Individualised treatment targets in patients with type-2 diabetes and hypertension
for the DIALOGUE study group, Schmieder, R. E., Tschöpe, D., Koch, C., Ouarrak, T., & Gitt, A. K. (2018) · Cardiovascular Diabetology · doi:10.1186/s12933-018-0661-8 · Cited by 21 · see citing works
Targets, Techniques, and Treatment Contexts in Emergent Literacy Intervention
Justice, L. M., Sofka, A., & McGinty, A. S. (2007) · Seminars in Speech and Language · doi:10.1055/s-2007-967926 · Cited by 19 · see citing works
Primary outcome measure use in back pain trials may need radical reassessment
Froud, R., Ellard, D. R., Patel, S., Eldridge, S. M., & Underwood, M. R. (2015) · BMC Musculoskeletal Disorders · doi:10.1186/s12891-015-0534-1 · Cited by 16 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LOC, Ostelo RW, et al. Motor control exercise for chronic non-specific low-back pain. In: Saragiotto BT, edi- tor. Cochrane Database Syst Rev 2016;(1):CD012004. Available from: http://www.ncbi.nlm.nih.gov/pubmed/26742533 [cited 3 August 2017].
- World Health Organization. Towards a common language for functioning, disability and health: ICF. Int Classif 2002;1149:1-22. Available from: http://www.who.int/classifications/ icf/training/icfbeginnersguide.pdf.
Cited by
Sorted by citations
Ho, E. K.-Y., Chen, L., Simic, M., Ashton-James, C. E., Comachio, J., Wang, D. X. M., Hayden, J. A., Ferreira, M. L., & Ferreira, P. H. (2022) · BMJ · doi:10.1136/bmj-2021-067718 · Cited by 220 · see citing works
Self-citationWood, L., Bejarano, G., Csiernik, B., Miyamoto, G. C., Mansell, G., Hayden, J. A., Lewis, M., & Cashin, A. G. (2023) · Journal of physiotherapy · doi:10.1016/j.jphys.2023.05.008 · Cited by 65 · see citing works
Self-citationCashin, A. G., Furlong, B., Kamper, S. J., Carvalho, D. E. D., Machado, L. A. C., Davidson, S. R. E., Bursey, K., Shaheed, C. A., & Hall, A. M. (2025) · BMJ Evidence-Based Medicine · doi:10.1136/bmjebm-2024-112974 · Cited by 33 · see citing works
The use of virtual nominal groups in healthcare research: An extended scoping review
Lee, S. H., ten Cate, O., Gottlieb, M. A., Horsley, T., Shea, B., Fournier, K., Tran, C. S., Chan, T. M., Wood, T. J., & Humphrey-Murto, S. M. (2024) · PLoS ONE · doi:10.1371/journal.pone.0302437 · Cited by 30 · see citing works
Prescription of therapeutic exercise for chronic low back pain management: a narrative review
Ganesh, G. S., Khan, A. R., Das, S. P., & Khan, A. (2023) · Bulletin of Faculty of Physical Therapy · doi:10.1186/s43161-023-00156-5 · Cited by 10 · see citing works
Sun, D., Wang, Z., Mou, J., Tian, F., Cao, J., Guo, L., & Liu, P. (2022) · Clinical Neurology and Neurosurgery · doi:10.1016/j.clineuro.2022.107484 · Cited by 10 · see citing works
Exercise treatments for chronic low back pain: a network meta-analysis
Hayden, J. A., Ogilvie, R., Kashif, S., Singh, S., Boulos, L., Stewart, S. A., Wieland, L. S., de Jesus‐Moraleida, F. R., Saragiotto, B. T., Yamato, T. P., et al. (2023) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd015608 · Cited by 9 · see citing works
Self-citationConsensus Methods for Health Research in a Global Setting
Carter, S. A., Tong, A., Craig, J. C., Teixeira-Pinto, A. M., & Manera, K. (2023) · Springer eBooks · doi:10.1007/978-3-031-25110-8_65 · Cited by 5 · see citing works
Humphrey, P., Dures, E. K., Hoskin, P., Johnston, J., Reardon, L., & Cramp, F. L. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-08997-z · Cited by 4 · see citing works
Mampel, J. V., Blanco-Gímenez, P., & Barrios, C. (2025) · Scientific Reports · doi:10.1038/s41598-025-22260-3 · Cited by 4 · see citing works
The use of virtual nominal groups in healthcare research: An extended scoping review
Lee, S. H., ten Cate, O., Gottlieb, M. A., Horsley, T., Shea, B., Fournier, K., Tran, C. S., Chan, T. M., Wood, T. J., & Humphrey-Murto, S. M. (2024) · doi:10.32920/27922062.v1 · Cited by 4 · see citing works
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Zebisch, J., & Diemer, F. (2022) · Schmerz Therapie · doi:10.1055/a-1756-8998 · Cited by 2 · see citing works
Bergevin, M., Bendas, A., Bobeuf, F., Gentile, E., Woznowski‐Vu, A., Wideman, T. H., Berryman, N., Bherer, L., Roy, M., & Pageaux, B. (2025) · Journal of science and medicine in sport · doi:10.1016/j.jsams.2025.07.003 · Cited by 2 · see citing works
Prevalence of Low Back Pain and Its Intensity Among Teachers of Universities in Lahore
Mushtaq, M., Qamar, S., Rafiq, S., Zia, S., Mohiuddin, M., Ghafoor, A., Saeed, M., & Iqbal, S. (2022) · Pakistan Journal of Health Sciences · doi:10.54393/pjhs.v3i06.309 · Cited by 2 · see citing works
Kałużna, A., Kałużny, K., Pyskir, M., Staniewska, A., Hagner–Derengowska, M., & Budzyński, J. (2023) · Medical Research Journal · doi:10.5603/mrj.a2023.0035 · Cited by 1 · see citing works
Consensus Methods for Health Research in a Global Setting
Carter, S. A., Tong, A., Craig, J. C., Teixeira-Pinto, A. M., & Manera, K. (2023) · Springer eBooks · doi:10.1007/978-3-030-96778-9_65-2 · Cited by 1 · see citing works
Bernaers, L., Willems, T. M., Lam, G. H., Mahy, M., Rusu, D., Demoulin, C., VELDE, D. V. D., & Braeckman, L. (2025) · Scientific Reports · doi:10.1038/s41598-025-97683-z · Cited by 2 · see citing works
Consensus Methods for Health Research in a Global Setting
Carter, S. A., Tong, A., Craig, J. C., Teixeira-Pinto, A. M., & Manera, K. (2023) · Springer eBooks · doi:10.1007/978-3-030-96778-9_65-1 · Cited by 1 · see citing works
Wood, L., Booth, V., Dean, S. G., Foster, N. E., Hayden, J. A., & Booth, A. (2024) · Systematic Reviews · doi:10.1186/s13643-024-02466-8
Self-citationThe use of virtual nominal groups in healthcare research: An extended scoping review
Lee, S. H., ten Cate, O., Gottlieb, M. A., Horsley, T., Shea, B., Fournier, K., Tran, C. S., Chan, T. M., Wood, T. J., & Humphrey-Murto, S. M. (2024) · doi:10.32920/27922062
Parolini, F. C. S., Becker, K. M., Goethel, M. F., Fernandes, R. J., Fonseca, H., Ervilha, U. F., Vilas‐Boas, J. P., & Santos, R. S. (2025) · Healthcare · doi:10.3390/healthcare13121471 · Cited by 1 · see citing works
Wood, L., Booth, V., Dean, S., Foster, N. E., Hayden, J. A., & Booth, A. (2024) · Figshare · doi:10.6084/m9.figshare.26678780
Self-citationA Chinese Guideline for the Diagnosis and Treatment of Chronic LOW Back Pain (2024 Edition)
Cheng, Z.-X., Liu, X.-G., Lu, Y., Ma, K., Dong, H., Liu, Q., Yang, X., Lu, L.-J., Liu, T.-H., Wang, L., et al. (2025) · International Journal of Pain Research · doi:10.11648/j.ijpr.20250104.14
Liu, S., Yang, J., Lei, B., Yage, W. A. N. G., Zhuang, W., & Liu, H. (2026) · Frontiers in Public Health · doi:10.3389/fpubh.2026.1965765
- Authors
- Wood, L., Bishop, A., Lewis, M., Smeets, R. J. E. M., Bronfort, G., Hayden, J. A., & Foster, N. E.
- Affiliations
- Nottingham University Hospitals NHS Trust (GB)
- Arthritis UK (GB)
- Maastricht University (NL)
- Dalhousie University (CA)
- Corresponding author
- Wood, Lianne
- Venue
- Physiotherapy
- Publisher
- Elsevier BV
- Published
- 2021-09
- Volume
- 112
- Pages
- 78-86
- ISSN
- 0031-9406 (ISSN-L)
- OpenAlex
- W3138358269
- Cited by
- 24
- References
- 43
- Citations by year
- 2026: 1 · 2025: 6 · 2024: 6 · 2023: 7 · 2022: 4
- FWCI
- 2.48
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Physiotherapy (publishedVersion)
- PubMed (publishedVersion)
- Research Publications (Maastricht University) (submittedVersion, other-oa)
- Keele Research Repository (Keele University) (submittedVersion, cc-by)
- Funders
- NIHR
- Keele University
- Topics
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Pregnancy-related medical research
- Health Sciences › Medicine › Pathology and Forensic Medicine › Spine and Intervertebral Disc Pathology
- Keywords
- non-specific low back pain, exercise intervention, treatment goals, exercise prescription, consensus, analgesia, quality of life, kinesiophobia, functional improvement, mediation analysis
- MeSH terms
- Back Pain, Exercise Therapy, Humans, Exercise, Low Back Pain
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