Cited by 266Plant Gene Expression AnalysisPlant biochemistry and biosynthesisPlant Molecular Biology Research

Multifunctional flavonoid dioxygenases: Flavonol and anthocyanin biosynthesis in Arabidopsis thaliana L

Martens, Stefan, Preuß, Anja, Matern, Ulrich·2010·Phytochemistry

Abstract

Flavonols and conditionally also anthocyanins, aside from flavonols, are the predominant polyphenols accumulated in various tissues of the model plant Arabidopsis thaliana L. In vitro experiments suggested that the dioxygenases involved in their biosynthesis, flavonol synthase and anthocyanidin synthase, are "multifunctional" enzymes showing distinct side activities. The in vivo relevance of the additional activities attributed to these enzymes, however, has remained obscure. In this review we summarize the most recent results and present final proof of the complementing activities of these synthases for flavonol and anthocyanidin formation in the model plant A. thaliana. The impact of their modification on the biosynthetic pathway and the pattern of flavonoids in different plant tissues are discussed.

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Crossref · 10.1016/j.phytochem.2010.04.016

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Authors
Martens, S., Preuß, A., & Matern, U.
Affiliations
  • Philipps University of Marburg (DE)
  • Technical University of Munich (DE)
Corresponding author
Martens, Stefan
Venue
Phytochemistry
Publisher
Elsevier BV
Published
2010-07
Volume
71
Issue
10
Pages
1040-1049
ISSN
0031-9422 (ISSN-L)
OpenAlex
W2047382548
Cited by
258
References
95
Citations by year
2026: 17 · 2025: 18 · 2024: 24 · 2023: 18 · 2022: 23 · 2021: 21 · 2020: 18 · 2019: 16 · 2018: 16 · 2017: 20 · 2016: 10 · 2015: 7 · 2014: 15 · 2013: 16 · 2012: 10
FWCI
0.98
Type
journal article
Language
en
Open access
closed
Locations
  • Phytochemistry (publishedVersion)
  • PubMed (publishedVersion)
Funders
Deutsche Forschungsgemeinschaft
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant Gene Expression Analysis
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
Keywords
flavonol biosynthesis, anthocyanin biosynthesis, flavonol synthase, anthocyanidin synthase, multifunctional enzyme, Arabidopsis thaliana, polyphenols, flavonoid biosynthesis
MeSH terms
Anthocyanins, Flavonoids, Arabidopsis, Flavonols, Dioxygenases

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