The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Comparative phenotypic characterization of human cord blood monocytes and placental macrophages at term
Abstract
The expression of surface molecules in cord blood monocytes and placental macrophages was studied using flow cytometry. When compared with monocytes, macrophages presented a decrease in HLA-DR and LAP/TGF-β1 levels and increased expression of alternative activation markers, especially CD206. No difference in the production of the apoptotic factors TRAIL and TWEAK was observed, whereas the levels of cytokine receptors in monocytes were significantly higher than in macrophages. Most remarkable was the difference in the expression of IL-17 and TNFα receptors. A strong correlation between VEGF and TNFα receptors was revealed in both cell populations. The results obtained in this study provide antigenic phenotypes for two related cell populations and outline the feasible functional alterations during tissue macrophage differentiation.
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“Increased cytokine expression does not only happen after trauma or infection, but also in physiologic states including pregnancy and other situations where increased cell proliferation and matrix deposition are required.8, 9, 10”
From Hypoalbuminemia: Pathogenesis and Clinical Significance (2019) · cites this paper as [9]
Citations
Cites
The Pathology of the Human Placenta
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Macrophage activation switching: an asset for the resolution of inflammation
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IL‐12 and IL‐23: master regulators of innate and adaptive immunity
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CD14: Cell surface receptor and differentiation marker
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Pathology of the Human Placenta
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Hypoalbuminemia: Pathogenesis and Clinical Significance
Soeters, P. B., Wolfe, R. R., & Shenkin, A. (2019) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1451 · Cited by 1,448
The Elusive Role of Placental Macrophages: The Hofbauer Cell
Zulu, M. Z., Martínez, F. O., Gordon, S., & Gray, C. M. (2019) · Journal of Innate Immunity · doi:10.1159/000497416 · Cited by 122
Schliefsteiner, C., Peinhaupt, M., Kopp, S., Loegl, J., Lang, I., Hiden, U., Heinemann, Á., Desoyé, G., & Wadsack, C. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00888 · Cited by 120
Placental Hofbauer Cell Polarization Resists Inflammatory Cues In Vitro
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Decidual macrophages and Hofbauer cells in fetal growth restriction
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Maternal-Fetal Interplay in Zika Virus Infection and Adverse Perinatal Outcomes
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De novo generation of macrophage from placenta-derived hemogenic endothelium
Liang, G., Zhou, C., Jiang, X., Zhang, Y., Huang, B., Gao, S., Kang, Z., Ma, D., Wang, F., Göttgens, B., et al. (2021) · Developmental Cell · doi:10.1016/j.devcel.2021.06.005 · Cited by 41
Macrophages are a source of IL‐17 in the human placenta
Павлов, О. В., Selutin, A. V., Pavlova, O., & Selkov, S. А. (2018) · American Journal of Reproductive Immunology · doi:10.1111/aji.13016 · Cited by 30
Self-citationTwo patterns of cytokine production by placental macrophages
Павлов, О. В., Selutin, A. V., Pavlova, O., & Selkov, S. А. (2020) · Placenta · doi:10.1016/j.placenta.2020.01.005 · Cited by 23
Self-citationПавлов, О. В., Niauri, D. A., Selutin, A. V., & Selkov, S. А. (2016) · Placenta · doi:10.1016/j.placenta.2016.04.008 · Cited by 18
Self-citationThe pathologic changes of human placental macrophages in women with hyperglycemia in pregnancy
Ning, J., Zhang, M., Cui, D., & Yang, H. (2022) · Placenta · doi:10.1016/j.placenta.2022.11.004 · Cited by 17
Tauber, Z., Burianova, A., Koubova, K., Mrstik, M., Jirkovská, M., & Čížková, K. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1386528 · Cited by 16
Characterization of fetal monocytes in preeclampsia and fetal growth restriction
Alahakoon, T. I., Medbury, H. J., Williams, H., Fewings, N., Wang, X. M., & Lee, V. W. (2019) · Journal of Perinatal Medicine · doi:10.1515/jpm-2018-0286 · Cited by 15
Zhang, M., Cui, D., & Yang, H. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.837391 · Cited by 14
Morphometric analysis of Hofbauer cells in normal placenta and chorioamnionitis in humans
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URFA, As’ád, S., Madjid, M., & Safitri, . (2023) · Nutrición clínica y dietética hospitalaria/Nutrición clínica, dietética hospitalaria · doi:10.12873/434urfa
Sex-influenced DNA methylation differs by placental cell type
Han, J., Inkster, A. M., Yuan, V., Peñaherrera, M. S., & Robinson, W. P. (2026) · Biology of Sex Differences · doi:10.1186/s13293-026-00869-x
Metadata
- Authors
- Selkov, S. A., Selutin, A. V., Pavlova, O. M., Khromov-Borisov, N. N., & Pavlov, O. V.
- Affiliations
- Research Institute of Obstetrics and Gynecology named after D.O. Ott (RU)
- First Pavlov State Medical University of St. Petersburg (RU)
- ORCID
- Pavlova, O.M.
- Venue
- Placenta
- Publisher
- Elsevier BV
- Published
- 2013-09
- Volume
- 34
- Issue
- 9
- Pages
- 836-839
- ISSN
- 0143-4004 (ISSN-L)
- OpenAlex
- W1971201518
- Cited by
- 19
- References
- 27
- Citations by year
- 2026: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 1 · 2020: 4 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 1
- FWCI
- 0.18
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Placenta (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Immunology › Immune cells in cancer
- Life Sciences › Immunology and Microbiology › Immunology › Reproductive System and Pregnancy
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Keywords
- cord blood monocytes, placental macrophages, macrophage differentiation, surface molecule expression, HLA-DR, CD206, alternative activation, TRAIL, TWEAK, cytokine receptors, IL-17 receptor, VEGF receptors, term pregnancy
- MeSH terms
- Mannose Receptor, Antigens, Differentiation, Cell Differentiation, Cells, Cultured, Cesarean Section, Female, Fetal Blood, Fetal Proteins, Flow Cytometry, HLA-DR Antigens, Humans, Macrophages, Monocytes, Placenta, Pregnancy, Pregnancy Trimester, Third, Receptors, Cell Surface, Surface Properties, Cytokines, Receptors, Cytokine, Gene Expression Regulation, Developmental, Lectins, C-Type, Mannose-Binding Lectins
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