Protective effects and mechanisms of sirtuins in the nervous system

Zhang, Feng, Wang, Suping, Gan, Li, Vosler, Peter S., Gao, Yanqin, Zigmond, Michael J., Chen, Jun·2011·Progress in Neurobiology
DOI 10.1016/j.pneurobio.2011.09.001

Cites (332)

Items 201–328 of 328

  1. Control of AIF-mediated Cell Death by the Functional Interplay of SIRT1 and PARP-1 in Response to DNA Damage
    Ullas Kolthur‐Seetharam, Françoise Dantzer, Michael W. McBurney, Gilbert de MURCIA, Paolo Sassone‐Corsi · 2006 · Cell Cycle
  2. Protection by tetrahydroxystilbene glucoside against cerebral ischemia: involvement of JNK, SIRT1, and NF-κB pathways and inhibition of intracellular ROS/RNS generation
    Ting Wang, Jun Fei Gu, Pengfei Wu, Fang Wang, Zhe Xiong, Yuan‐Jian Yang, Wen‐Ning Wu, Ling-Dan Dong, Jianguo Chen · 2009 · Free Radical Biology and Medicine
  3. Neuroprotection against focal ischemic brain injury by the peroxisome proliferator‐activated receptor‐γ agonist rosiglitazone
    Yumin Luo, Wei Yin, Armando P. Signore, Feng Zhang, Zhen Hong, Suping Wang, Steven H. Graham, Jun Chen · 2006 · Journal of Neurochemistry
  4. Alternative mechanisms of initiating translation of mammalian mRNAs
    Richard J. Jackson · 2005 · Biochemical Society Transactions
  5. Translation by ribosome shunting on adenovirus and hsp70 mRNAs facilitated by complementarity to 18S rRNA
    Andrew Yueh, Robert J. Schneider · 2000 · Genes & Development
  6. Oral Resveratrol Reduces Neuronal Damage in a Model of Multiple Sclerosis
    Kenneth S. Shindler, Elvira S. Ventura, Mahasweta Dutt, Peter J. Elliott, Denise C. Fitzgerald, Abdolmohamad M. Rostami · 2010 · Journal of Neuro-Ophthalmology
  7. Resveratrol protects dopaminergic neurons in midbrain slice culture from multiple insults
    Mitsugi Okawara, Hiroshi Katsuki, Emi Kurimoto, Haruki Shibata, Toshiaki Kume, Akinori Akaike · 2006 · Biochemical Pharmacology
  8. Cytoplasm‐localized SIRT1 enhances apoptosis
    Qihuang Jin, Tingting Yan, Xinjian Ge, Cheng Sun, Xianglin Shi, Qiwei Zhai · 2007 · Journal of Cellular Physiology
  9. Dietary oxyresveratrol prevents parkinsonian mimetic 6-hydroxydopamine neurotoxicity
    Jianfei Chao, Man-Shan Yu, Janice Yuen Shan Ho, Mingfu Wang, Raymond Chuen‐Chung Chang · 2008 · Free Radical Biology and Medicine
  10. Structural basis for nicotinamide cleavage and ADP-ribose transfer by NAD + -dependent Sir2 histone/protein deacetylases
    Kehao Zhao, Robyn B Harshaw, Xiaomei Chai, Ronen Marmorstein · 2004 · Proceedings of the National Academy of Sciences
  11. Calorie restriction attenuates Alzheimer's disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
    Weiping Qin, Mark E. Chachich, Mark A. Lane, George Roth, Mark Bryant, Rafael de Cabo, Mary Ann Ottinger, Julie A. Mattison, Donald Ingram, Sam Gandy et al. · 2006 · Journal of Alzheimer s Disease
  12. Neuroprotective Effects of Leptin Against Ischemic Injury Induced by Oxygen-Glucose Deprivation and Transient Cerebral Ischemia
    Feng Zhang, Suping Wang, Armando P. Signore, Jun Chen · 2007 · Stroke
  13. Predominant expression of Sir2α, an NAD‐dependent histone deacetylase, in the embryonic mouse heart and brain1
    Jun Sakamoto, Tetsuji Miura, Kazuaki Shimamoto, Yoshiyuki Horio · 2003 · FEBS Letters
  14. Neural sirtuin 6 (Sirt6) ablation attenuates somatic growth and causes obesity
    Bjoern Schwer, Björn Schumacher, David B. Lombard, Cuiying Xiao, Martin V. Kurtev, Jun Gao, Jennifer I. Schneider, Hua Chai, Roderick Terry Bronson, Li‐Huei Tsai et al. · 2010 · Proceedings of the National Academy of Sciences
  15. Regulation of Neuronal Cell Death by MST1-FOXO1 Signaling
    Zengqiang Yuan, Maria K. Lehtinen, Paola Merlo, Judit Villén, Steven P. Gygi, Azad Bonni · 2009 · Journal of Biological Chemistry
  16. SIRT1 deacetylates APE1 and regulates cellular base excision repair
    Tohru Yamamori, Jeremy S. DeRicco, Asma Naqvi, Timothy A. Hoffman, Ilwola Mattagajasingh, Kenji Kasuno, Saet-Byel Jung, Cuk‐Seong Kim, Kaikobad Irani · 2009 · Nucleic Acids Research
  17. Liver X Receptor Agonist Treatment Ameliorates Amyloid Pathology and Memory Deficits Caused by High-Fat Diet in APP23 Mice
    Fitz, Nicholas F., Cronican, Andrea, Pham, Tam, Fogg, Allison, Fauq, Abdul H., Chapman, Robert, Lefterov, Iliya, Koldamova, Radosveta · 2010 · The Journal of Neuroscience
  18. SIRT1 Activation Confers Neuroprotection in Experimental Optic Neuritis
    Kenneth S. Shindler, Elvira S. Ventura, Tonia S. Rex, Peter J. Elliott, Abdolmohamad M. Rostami · 2007 · Investigative Ophthalmology & Visual Science
  19. Axonal and neuronal pathology in multiple sclerosis: What have we learnt from animal models
    Hans Lassmann · 2009 · Experimental Neurology
  20. The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo
    Dmitriy N. Atochin, Annie R. Wang, Victor W.T. Liu, Jeffrey D. Critchlow, Ana Paula Dantas, Robin Christine Looft‐Wilson, Takahisa Murata, Salvatore Salomone, Hwa Kyoung Shin, Cenk Ayata et al. · 2007 · Journal of Clinical Investigation
  21. PTEN Acetylation Modulates Its Interaction with PDZ Domain
    Tsuneo Ikenoue, Ken Inoki, Bin Zhao, Kun‐Liang Guan · 2008 · Cancer Research
  22. SIRT1 stimulation by polyphenols is affected by their stability and metabolism
    Vincent C. J. de Boer, Marcus Christofoor de Goffau, Ilja C.W. Arts, Peter C.H. Hollman, Jaap Keijer · 2006 · Mechanisms of Ageing and Development
  23. The SIRT2 Deacetylase Regulates Autoacetylation of p300
    Joshua C. Black, Amber L. Mosley, Tasuku Kitada, Michael P. Washburn, Michael Carey · 2008 · Molecular Cell
  24. NAD+-dependent Deacetylase SIRT3 Regulates Mitochondrial Protein Synthesis by Deacetylation of the Ribosomal Protein MRPL10
    Yongjie Yang, Hüseyin Çimen, Min-Joon Han, Tong Shi, Jian Deng, Hasan Koç, Orsolya M Palacios, Laura Montier, Yidong Bai, Qiang Tong et al. · 2009 · Journal of Biological Chemistry
  25. Neuronal Sirt3 Protects against Excitotoxic Injury in Mouse Cortical Neuron Culture
    Sun Hee Kim, Hua Lu, Conrad C. Alano · 2011 · PLoS ONE
  26. Yeast Life-Span Extension by Calorie Restriction Is Independent of NAD Fluctuation
    Rozalyn M. Anderson, Magda Latorre‐Esteves, Ana Rute Neves, Siva Lavu, Oliver Medvedik, Christopher Taylor, Konrad T. Howitz, Helena Santos, David A. Sinclair · 2003 · Science
  27. Transgenic Mice Expressing the Nmnat1 Protein Manifest Robust Delay in Axonal Degeneration In Vivo
    Sasaki, Yo, Vohra, Bhupinder P. S., Baloh, Robert H., Milbrandt, Jeffrey · 2009 · The Journal of Neuroscience
  28. Hibernation in Ground Squirrels Induces State and Species-Specific Tolerance to Hypoxia and Aglycemia: An In Vitro Study in Hippocampal Slices
    Kai U. Frerichs, John M. Hallenbec · 1998 · Journal of Cerebral Blood Flow & Metabolism
  29. Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease
    Daniel J. Ho, Noel Ylagan Calingasan, Elizabeth J. Wille, Magali Dumont, M. Flint Beal · 2010 · Experimental Neurology
  30. Regulation of global genome nucleotide excision repair by SIRT1 through xeroderma pigmentosum C
    Mei Ming, Christopher R. Shea, Xiumei Guo, Xiaoling Li, Keyoumars Soltani, Weinong Han, Yu-Ying He · 2010 · Proceedings of the National Academy of Sciences
  31. SIRT3 is Pro-Apoptotic and Participates in Distinct Basal Apoptotic Pathways
    Simon J. Allison, J Milner · 2007 · Cell Cycle
  32. Resveratrol neuroprotective effects during focal cerebral ischemia injury via nitric oxide mechanism in rats
    Shen-Kou Tsai, Li‐Man Hung, Yuan-Tsung Fu, Henrich Cheng, Mao-Wei Nien, Hsin-Yi Liu, Friedrich Bo-Yuan Zhang, Shiang-Suo Huang · 2007 · Journal of Vascular Surgery
  33. Division and apoptosis of E2f-deficient retinal progenitors
    Chen, Danian, Pacal, Marek, Wenzel, Pamela, Knoepfler, Paul S., Leone, Gustavo, Bremner, Rod · 2009 · Nature
  34. WldS requires Nmnat1 enzymatic activity and N16–VCP interactions to suppress Wallerian degeneration
    Michelle A. Avery, Amy E. Sheehan, Kimberly S. Kerr, Jing Wang, Marc R. Freeman · 2009 · The Journal of Cell Biology
  35. Poly(ADP-ribose)polymerase 1 (PARP-1) and postischemic brain damage
    Flavio Moroni · 2007 · Current Opinion in Pharmacology
  36. NAD+ and axon degeneration revisited: Nmnat1 cannot substitute for WldS to delay Wallerian degeneration
    L Conforti, Guofu Fang, Bogdan Beirowski, M S Wang, Leonardo Sorci, S Asress, Róbert Adalbert, A Silva, Katherine Bridge, X P Huang et al. · 2006 · Cell Death and Differentiation
  37. Evidence that the Rate of Wallerian Degeneration is Controlled by a Single Autosomal Dominant Gene
    Victor Hugh Perry, E. R. Lunn, M. C. Brown, S. Cahusac, Siamon Gordon · 1990 · European Journal of Neuroscience
  38. Sirtuin activators
    Alcaín, Francisco J, Villalba, José M · 2009 · Expert Opinion on Therapeutic Patents
  39. The human SIRT3 protein deacetylase is exclusively mitochondrial
    Helen M. Cooper, Johannes N. Spelbrink · 2008 · Biochemical Journal
  40. Icariin protects against brain injury by enhancing SIRT1-dependent PGC-1α Expression in experimental stroke
    Hai-rong Zhu, Zhongyuan Wang, Xiaolei Zhu, Xiaoxin Wu, Erguang Li, Yun Xu · 2010 · Neuropharmacology
  41. CK2 Is the Regulator of SIRT1 Substrate-Binding Affinity, Deacetylase Activity and Cellular Response to DNA-Damage
    Hyeog Kang, Jaewon Jung, Myung K. Kim, Jay H. Chung · 2009 · PLoS ONE
  42. APE1 is the major 3'-phosphoglycolate activity in human cell extracts
    Jason Luke Parsons · 2004 · Nucleic Acids Research
  43. Protection by EGb 761 against β-amyloid-induced neurotoxicity: Involvement of NF-κB, SIRT1, and MAPKs pathways and inhibition of amyloid fibril formation
    Fanny Longpré, Philippe Garneau, Yves Christen, Charles Ramassamy · 2006 · Free Radical Biology and Medicine
  44. Neurological symptoms and natural course of xeroderma pigmentosum
    Anttinen, A., Koulu, L., Nikoskelainen, E., Portin, R., Kurki, T., Erkinjuntti, M., Jaspers, N. G. J., Raams, A., Green, M. H. L., Lehmann, A. R. et al. · 2008 · Brain
  45. Pathways for Ischemic Cytoprotection: Role of Sirtuins in Caloric Restriction, Resveratrol, and Ischemic Preconditioning
    Kahlilia C. Morris, Hung Wen Lin, John W. Thompson, Miguel A. Pérez‐Pinzón · 2011 · Journal of Cerebral Blood Flow & Metabolism
  46. Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2
    Golnar Afshar, John P. Murnane · 1999 · Gene
  47. Lysine deacetylation in ischaemic preconditioning: the role of SIRT1
    Nadtochiy, Sergiy M., Redman, Emily, Rahman, Irfan, Brookes, Paul S. · 2011 · Cardiovascular Research
  48. Localization of mouse mitochondrial SIRT proteins: Shift of SIRT3 to nucleus by co-expression with SIRT5
    Yasuhiko Nakamura, Masahito Ogura, Daisuke Tanaka, Nobuya Inagaki · 2007 · Biochemical and Biophysical Research Communications
  49. 4-hydroxynonenal inhibits SIRT3 via thiol-specific modification
    Fritz, Kristofer S., Galligan, James J., Smathers, Rebecca L., Roede, James R., Shearn, Colin T., Reigan, Philip, Petersen, Dennis R. · 2011 · Chemical Research in Toxicology
  50. The Sirtuin Inhibitor Nicotinamide Enhances Neuronal Cell Survival During Acute Anoxic Injury Through AKT, BAD, PARP, and Mitochondrial Associated "Anti-Apoptotic" Pathways
    Zhao Zhong Chong, Shan Lin, F. Li, Kenneth Maiese · 2005 · Current Neurovascular Research
  51. Hypoxia‐inducible factor 1: a new hope to counteract neurodegeneration?
    Sónia C. Correia, Paula Isabel Moreira · 2009 · Journal of Neurochemistry
  52. Targeting NMNAT1 to Axons and Synapses Transforms Its Neuroprotective PotencyIn Vivo
    Elisabetta Babetto, Bogdan Beirowski, Lucie Janečková, Rosalind Brown, Jonathan Gilley, Derek Thomson, Richard R. Ribchester, Michael P. Coleman · 2010 · Journal of Neuroscience
  53. Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: Potential signaling mechanisms
    Feng Zhang, Armando P. Signore, Zhigang Zhou, Suping Wang, Guodong Cao, Jun Chen · 2006 · Journal of Neuroscience Research
  54. Intranasal administration with NAD+ profoundly decreases brain injury in a rat model of transient focal ischemia
    Weihai Ying · 2006 · Frontiers in bioscience
  55. Mammalian Sir2-related protein (SIRT) 2–mediated modulation of resistance to axonal degeneration in slow Wallerian degeneration mice: A crucial role of tubulin deacetylation
    Kazuhiko Suzuki, Takayoshi Koike · 2007 · Neuroscience
  56. Function and metabolism of sirtuin metabolite O-acetyl-ADP-ribose
    Lei Tong, John M. Denu · 2010 · Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
  57. Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions
    Damiano Fantini, Carlo Vascotto, Daniela Marasco, Chiara DˈAmbrosio, Milena Romanello, Luigi Vitagliano, Carlo Pedone, Mattia Poletto, Laura Cesaratto, Franco Quadrifoglio et al. · 2010 · Nucleic Acids Research
  58. Overexpression of SIRT5 confirms its involvement in deacetylation and activation of carbamoyl phosphate synthetase 1
    Ogura, Masahito, Nakamura, Yasuhiko, Tanaka, Daisuke, Zhuang, Xiaotong, Fujita, Yoshihito, Obara, Akio, Hamasaki, Akihiro, Hosokawa, Masaya, Inagaki, Nobuya · 2010 · Biochemical and Biophysical Research Communications
  59. Nuclear genes and mitochondrial translation: a new class of genetic disease
    Howard Trevor Jacobs, D TURNBULL · 2005 · Trends in Genetics
  60. Cellular NAD Replenishment Confers Marked Neuroprotection Against Ischemic Cell Death
    Suping Wang, Zili Xing, Peter S. Vosler, Hannah Yin, Wenjin Li, Feng Zhang, Armando P. Signore, Ruth Anne Stetler, Yanqin Gao, Jun Chen · 2008 · Stroke
  61. WldS protein requires Nmnat activity and a short N-terminal sequence to protect axons in mice
    Laura Conforti, Anna L. Wilbrey, Giacomo Morreale, Lucie Janečková, Bogdan Beirowski, Róbert Adalbert, Francesca Mazzola, M. Di Stefano, Robert Hartley, Elisabetta Babetto et al. · 2009 · The Journal of Cell Biology
  62. VEGF overexpression enhances striatal neurogenesis in brain of adult rat after a transient middle cerebral artery occlusion
    Yong‐Quan Wang, Xin Guo, Mei‐Hong Qiu, Xiaoyuan Feng, Feng‐Yan Sun · 2006 · Journal of Neuroscience Research
  63. Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti‐aging and metabolic effects of sirtuins
    Ivy Ka Man Law, Ling Liu, Aimin Xu, Karen S.L. Lam, Paul M. Vanhoutte, Chi‐Ming Che, Priscilla T.Y. Leung, Yu Wang · 2009 · PROTEOMICS
  64. Modulation of SIRT1 expression in different neurodegenerative models and human pathologies
    Mercè Pallàs, Javier G. Pizarro, Javier Cuesta, Natàlia Crespo‐Biel, Daniel Alvira, Marta Tajes, Marc Yeste‐Velasco, Jaume Folch, Anna Maria Canudas, Francesc Xavier Sureda et al. · 2008 · Neuroscience
  65. Controlling SIRT1 expression by microRNAs in health and metabolic disease
    Ji‐Young Lee, Jongsook Kim Kemper · 2010 · Aging
  66. Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1
    Lin Wang, Ling Zhang, Zhibin Chen, Jiayong Wu, Xin Zhang, Yun Xu · 2009 · European Journal of Pharmacology
  67. Poly(ADP-ribose) polymerase-1 modulates DNA repair capacity and prevents formation of DNA double strand breaks
    Bethany C. Woodhouse, Irina I. Dianova, Jason Luke Parsons, Grigory L. Dianov · 2008 · DNA repair
  68. Sirt1 inhibition promotes in vivo arterial thrombosis and tissue factor expression in stimulated cells
    Alexander Breitenstein, Sokrates Stein, Erik Walter Holy, Giovanni Guido Camici, Christine Lohmann, Alexander Akhmedov, Remo D. Spescha, Peter J. Elliott, Christoph Heiner Westphal, Christian M. Matter et al. · 2010 · Cardiovascular Research
  69. Resveratrol and Ischemic Preconditioning in the Brain
    Ami P. Raval, Hung Wen Lin, Kunjan R. Dave, Richard Anthony DeFazio, David Della‐Morte, Eun Joo Kim, Miguel A. Pérez‐Pinzón · 2008 · Current Medicinal Chemistry
  70. Brain molecular aging, promotion of neurological disease and modulation by Sirtuin5 longevity gene polymorphism
    Christin A. Glorioso, Sunghee Oh, Gaëlle Douillard‐Guilloux, Etienne L. Sibille · 2010 · Neurobiology of Disease
  71. Stability Regulation of mRNA and the Control of Gene Expression
    Chris Cheadle, Jinshui Fan, Yoon S. Cho‐Chung, Thomas Artur Werner, Jill Ray, Lana Do, Myriam Gorospe, Kevin G. Becker · 2005 · Annals of the New York Academy of Sciences
  72. Minireview: The PGC-1 Coactivator Networks: Chromatin-Remodeling and Mitochondrial Energy Metabolism
    Jiandie D. Lin · 2008 · Molecular Endocrinology
  73. p53-mediated neuronal cell death in ischemic brain injury
    Li-Zhi Hong, Xiao-Yuan Zhao, Hui-Ling Zhang · 2010 · Neuroscience Bulletin
  74. Foxo3a induces motoneuron death through the Fas pathway in cooperation with JNK
    Catherine Barthélémy, Christopher E. Henderson, Brigitte Pettmann · 2004 · BMC Neuroscience
  75. MST1 Promotes Apoptosis through Regulating Sirt1-dependent p53 Deacetylation
    Fang Yuan, Qi Xie, Junbing Wu, Yujie Bai, Beibei Mao, Yongli Dong, Wenzhi Bi, Guangju Ji, Wufan Tao, Yan Wang et al. · 2011 · Journal of Biological Chemistry
  76. Comparative analysis of the effects of resveratrol in two apoptotic models: Inhibition of complex I and potassium deprivation in cerebellar neurons
    Daniel Alvira, Marc Yeste‐Velasco, Jaume Folch, Ester Verdaguer, Anna Maria Canudas, Mercè Pallàs, Antoni Camins · 2007 · Neuroscience
  77. Uncoupling of Endothelial Nitric Oxide Synthase after Experimental Subarachnoid Hemorrhage
    Mohammed Sabri, Jinglu Ai, Britta J. Knight, Asma Tariq, Hyojin Jeon, Xueyuan Shang, Philip A. Marsden, Robert Loch Macdonald · 2010 · Journal of Cerebral Blood Flow & Metabolism
  78. FOXO3a Is Broadly Neuroprotective In Vitro and In Vivo against Insults Implicated in Motor Neuron Diseases
    Jelena Mojsilovic‐Petrovic, Natalia B. Nedelsky, Marco Boccitto, I. Mano, Savvas N. Georgiades, W. Zhou, Y. Liu, Rachael L. Neve, J. Paul Taylor, Monica Driscoll et al. · 2009 · Journal of Neuroscience
  79. The Conserved Core of a HumanSIR2Homologue Functions in Yeast Silencing
    Joyce M. Sherman, Elisa M. Stone, Lisa L. Freeman-Cook, Carrie Baker Brachmann, Jef D. Boeke, Lorraine Pillus · 1999 · Molecular Biology of the Cell
  80. SIRT1 Deficiency Downregulates PTEN/JNK/FOXO1 Pathway to Block Reactive Oxygen Species-Induced Apoptosis in Mouse Embryonic Stem Cells
    Hee-Don Chae, Hal E. Broxmeyer · 2010 · Stem Cells and Development
  81. Apoptosis in cerebral ischemia: executional and regulatory signaling mechanisms
    Feng Zhang, Wei Yin, Jun Chen · 2004 · Neurological Research
  82. Leptin Is Induced in the Ischemic Cerebral Cortex and Exerts Neuroprotection Through NF-κB/c-Rel–Dependent Transcription
    Alessandra Valerio, Marta Dossena, Paola Bertolotti, Flora Boroni, Ilenia Sarnico, Giuseppe Faraco, Alberto Chiarugi, Andrea Frontini, Antonio Giordano, Hsiou‐Chi Liou et al. · 2008 · Stroke
  83. Death-associated Protein 4 Binds MST1 and Augments MST1-induced Apoptosis
    Yenshou Lin, Andrei V. Khokhlatchev, Daniel Figeys, Joseph Avruch · 2002 · Journal of Biological Chemistry
  84. HDAC3 Is Negatively Regulated by the Nuclear Protein DBC1
    Claudia C.S. Chini, Carlos Escande, Verónica Nin, Eduardo N. Chini · 2010 · Journal of Biological Chemistry
  85. Resveratrol prevents antibody-induced apoptotic death of retinal cells through upregulation of Sirt1 and Ku70
    Thimmappa S. Anekonda, Grazyna Adamus · 2008 · BMC Research Notes
  86. SIRTUIN 1: Regulating the regulator
    Barbara Zschoernig, Ulrich Mahlknecht · 2008 · Biochemical and Biophysical Research Communications
  87. SIRT1 markedly extends replicative lifespan if the NAD+ salvage pathway is enhanced
    Cynthia Ho, Eric van der Veer, Oula Akawi, J. Geoffrey Pickering · 2009 · FEBS Letters
  88. Cerebral Endothelial Cell Apoptosis after Ischemia—Reperfusion: Role of PARP Activation and AIF Translocation
    Yunhong Zhang, Xiaochun Zhang, T.S. Park, Jeffrey M. Gidday · 2005 · Journal of Cerebral Blood Flow & Metabolism
  89. Apurinic/apyrimidinic endonuclease APE1 is required for PACAP-induced neuroprotection against global cerebral ischemia
    Ruth Anne Stetler, Yanqin Gao, R. Suzanne Zukin, Peter S. Vosler, Lili Zhang, Feng Zhang, Guodong Cao, Michael V. L. Bennett, Jun Chen · 2010 · Proceedings of the National Academy of Sciences
  90. Pharmacological inhibition of PARP-1 reduces α-synuclein- and MPP+-induced cytotoxicity in Parkinson’s disease in vitro models
    Tiago F. Outeiro, Tom N. Grammatopoulos, Steven Altmann, Allison M. Amore, David G. Standaert, Bradley T. Hyman, Aleksey G. Kazantsev · 2007 · Biochemical and Biophysical Research Communications
  91. Inhibitors of NAD+ Dependent Histone Deacetylases (Sirtuins)
    Manfred Jung, Robert C. Neugebauer, Wolfgang Sippl · 2008 · Current Pharmaceutical Design
  92. Activation of Akt/FoxO signaling pathway contributes to induction of neuroprotection against transient global cerebral ischemia by hypoxic pre‐conditioning in adult rats
    Lixuan Zhan, Tao Wang, Wen Li, Zao Cheng Xu, Weiwen Sun, En Xu · 2010 · Journal of Neurochemistry
  93. Leptin protects hippocampal CA1 neurons against ischemic injury
    Feng Zhang, Jun Chen · 2008 · Journal of Neurochemistry
  94. Enhanced Tolerance against Early and Late Apoptotic Oxidative Stress in Mammalian Neurons through Nicotinamidase and Sirtuin Mediated Pathways
    Zhao Zhong Chong, Kenneth Maiese · 2008 · Current Neurovascular Research
  95. SIRT1, a histone deacetylase, regulates prion protein-induced neuronal cell death
    Jae‐Suk Seo, Myung‐Hee Moon, Jae‐Kyo Jeong, Jae‐Won Seol, You-Jin Lee, Byung‐Hyun Park, Sang‐Youel Park · 2010 · Neurobiology of Aging
  96. Activation of liver X receptor reduces global ischemic brain injury by reduction of nuclear factor-κB
    O. Cheng, Robert P. Ostrowski, Wenwu Liu, Jianghong Zhang · 2010 · Neuroscience
  97. The Importance of NAD in Multiple Sclerosis
    William Todd Penberthy, Ikuo Tsunoda · 2009 · Current Pharmaceutical Design
  98. Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection
    Kenichi Kakefuda, Yasunori Fujita, Atsushi Oyagi, Kana Hyakkoku, Toshio Kojima, Ken Umemura, Kazuhiro Tsuruma, Masamitsu Shimazawa, Masafumi Ito, Yoshinori Nozawa et al. · 2009 · Biochemical and Biophysical Research Communications
  99. The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration
    Danica Chen, Andrew D. Steele, Gregor Hütter, Joanne Bruno, Arvind Govindarajan, Erin J. Easlon, Su-Ju Lin, Adriano Aguzzi, Susan Lee Lindquist, Leonard Guarente · 2008 · Experimental Gerontology
  100. Carboxy-terminal phosphorylation of SIRT1 by protein kinase CK2
    Barbara Zschoernig, Ulrich Mahlknecht · 2009 · Biochemical and Biophysical Research Communications
  101. Ischemic Preconditioning in the Rat Brain Enhances the Repair of Endogenous Oxidative DNA Damage by Activating the Base-Excision Repair Pathway
    Wenjin Li, Yumin Luo, Feng Zhang, Armando P. Signore, Glenn T. Gobbel, Roger Pancoast Simon, Jun Chen · 2005 · Journal of Cerebral Blood Flow & Metabolism
  102. Peroxisome Proliferator-Activated Receptor-α Activation Protects Brain Capillary Endothelial Cells from Oxygen-Glucose Deprivation-Induced Hyperpermeability in the Blood-Brain Barrier
    Caroline Mysiorek, Maxime Culot, Lucie Dehouck, Bruno Derudas, Bart Staels, Régis Bordet, Roméo Cecchelli, Laurence Fénart, Vincent Bérézowski · 2009 · Current Neurovascular Research
  103. Post‐ischemic brain damage: NF‐κB dimer heterogeneity as a molecular determinant of neuron vulnerability
    Marina Pizzi, Ilenia Sarnico, Annamaria Lanzillotta, Leontino Battistin, PierFranco Spano · 2008 · FEBS Journal
  104. Resveratrol inhibits MMP-9 expression by up-regulating PPAR α expression in an oxygen glucose deprivation-exposed neuron model
    Gang Cheng, Xiang Zhang, Dakuan Gao, Xiaofan Jiang, Wenpeng Dong · 2008 · Neuroscience Letters
  105. The mitochondria permeability transition pore complex in the brain with interacting proteins – promising targets for protection in neurodegenerative diseases
    Tamara Azarashvili, Rolf Stricker, Georg Reiser · 2010 · Biological Chemistry
  106. Mice knock out for the histone acetyltransferase p300/CREB binding protein-associated factor develop a resistance to amyloid toxicity
    Florian Duclot, Julie Meffre, Chantal Jacquet, Céline Gongora, Tangui Maurice · 2010 · Neuroscience
  107. A Single-Dose Resveratrol Treatment in a Mouse Model of Amyotrophic Lateral Sclerosis
    Chad D. Markert, Eunkuk Kim, David J. Gifondorwa, Martin K. Childers, Carol Milligan · 2010 · Journal of Medicinal Food
  108. Biochemical pathways that regulate acetyltransferase and deacetylase activity in mammalian cells
    Hestia S. Mellert, Steven B. McMahon · 2009 · Trends in Biochemical Sciences
  109. Transcriptional activation of NAD+-dependent protein deacetylase SIRT1 by nuclear receptor TLX
    Naotoshi Iwahara, Shin Hisahara, Takashi Hayashi, Yoshiyuki Horio · 2009 · Biochemical and Biophysical Research Communications
  110. Early Decrease in DNA Repair Proteins, Ku70 and Ku86, and Subsequent DNA Fragmentation After Transient Focal Cerebral Ischemia in Mice
    Gyung Whan Kim, Nobuo Noshita, Taku Sugawara, Pak Hoo Chan · 2001 · Stroke
  111. Enhanced Delivery of Erythropoietin Across the Blood–Brain Barrier for Neuroprotection Against Ischemic Neuronal Injury
    Feng Zhang, Juan Xing, Anthony K. F. Liou, Suping Wang, Yu Gan, Yumin Luo, Xunming Ji, Ruth Anne Stetler, Jun Chen, Guodong Cao · 2010 · Translational Stroke Research
  112. Role of Pax3 acetylation in the regulation ofHes1andNeurog2
    Shunsuke Ichi, Vanda Boshnjaku, Yueh-Wei Shen, Barbara L. Mania-Farnell, Sara C. Ahlgren, Sidanth Sapru, Nikhita D. Mansukhani, David G. McLone, Tadanori Tomita, Chandra Shekhar K. Mayanil · 2010 · Molecular Biology of the Cell
  113. Resveratrol is neuroprotective because it is not a direct activator of Sirt1—A hypothesis
    Bor Luen Tang · 2009 · Brain Research Bulletin
  114. Neuron Dysfunction Is Induced by Prion Protein with an Insertional Mutation via a Fyn Kinase and Reversed by Sirtuin Activation inCaenorhabditis elegans
    Nicolas Bizat, Jean‐Michel Peyrin, Stéphane Haı̈k, Véronique Cochois, P. Beaudry, Jean Laplanche, Christian Néri · 2010 · Journal of Neuroscience
  115. Role of Nrf2-Dependent ARE-Driven Antioxidant Pathway in Neuroprotection
    Jiang Li, Marcus J. Calkins, Delinda A. Johnson, Jeffrey Allan Johnson · 2007 · Methods in molecular biology
  116. Leptin Reduces Infarct Size in Association with Enhanced Expression of CB2, TRPV1, SIRT-1 and Leptin Receptor
    Yosefa Avraham, N. Davidi, Moran Porat, D. Chernoguz, Iddo Magen, Lia Vorobeiv, Elliot M. Berry, Ronen R. Leker · 2010 · Current Neurovascular Research
  117. Modulation of Microglial Innate Immunity in Alzheimers Disease by Activation of Peroxisome Proliferator-activated Receptor Gamma
    Feng‐Shiun Shie, Mary P. Nivison, Pei-Chien Hsu, Thomas Jude Montine · 2009 · Current Medicinal Chemistry
  118. Shut-Down of Translation, a Global Neuronal Stress Response:Mechanisms and Pathological Relevance
    Wulf Paschen, Christopher G. Proud, Günter Mies · 2007 · Current Pharmaceutical Design
  119. Neuronal Expression of the DNA Repair Protein Ku 70 After Ischemic Preconditioning Corresponds to Tolerance to Global Cerebral Ischemia
    Taku Sugawara, Nobuo Noshita, Anders Lewén, Gyung Whan Kim, Pak Hoo Chan · 2001 · Stroke
  120. Sir2 is induced by oxidative stress in a yeast model of Huntington disease and its activation reduces protein aggregation
    Maria Alba Sorolla, Clara Nierga, Maria J. Rodríguez Colman, Gemma Reverter‐Branchat, Alicia Arenas, Jordi Tamarit, Joaquim Ros, Elisa Cabiscol · 2011 · Archives of Biochemistry and Biophysics
  121. Sirt1’s Complex Roles in Neuroprotection
    Bor Luen Tang · 2009 · Cellular and Molecular Neurobiology
  122. Knockdown of FoxO3a induces increased neuronal apoptosis during embryonic development in zebrafish
    Kou Peng, Yi Li, Ling Long, Dong Li, Qiuli Jia, Yidong Wang, Qingyu Shen, Yamei Tang, Lu Wen, Hsiang‐Fu Kung et al. · 2010 · Neuroscience Letters
  123. NF-κΒ Signaling in Neurite Growth and Neuronal Survival
    Felicia Yu Hsuan Teng, Bor Luen Tang · 2010 · Reviews in the Neurosciences
  124. Evidence that core histone H3 is targeted to the mitochondria in Brassica oleracea
    Mary K.B. Zanin, Jon M. Donohue, Bryan A. Everitt · 2010 · Cell Biology International
  125. DNA-binding proteins of mammalian mitochondria
    Michael P. Kutsyi, N. A. Gouliaeva, E. Kuznetsova, A.I. Gaziev · 2005 · Mitochondrion
  126. Neurodegeneration in xeroderma pigmentosum
    Alexander Malcolm R. Taylor · 2008 · Brain
  127. Untitled work
    1999 · 10.1002/(sici)1097-4547(19990915)57:6
  128. Untitled work
    1999 · 10.1002/(sici)1097-4547(19990715)57:2