Tuning polycaprolactone degradation for long acting implantables
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PCL is often blended with polymers such as PLA or PEG to accelerate degradation and improve cytocompatibility.
“To address this, PCL is often blended with polymers such as PLA or PEG to not only accelerate degradation, but also improve cytocompatibility [198].”
From Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering (2025) · cites this paper as [198]
Cites
Degradation mechanisms of polycaprolactone in the context of chemistry, geometry and environment
Bartnikowski, M., Dargaville, T. R., Ivanovski, S., & Hutmacher, D. W. (2019) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2019.05.004 · Cited by 769 · see citing works
Lam, C. X. F., Savalani, M. M., Teoh, S.-H., & Hutmacher, D. W. (2008) · Biomedical Materials · doi:10.1088/1748-6041/3/3/034108 · Cited by 444 · see citing works
Chain-end scission in acid catalyzed hydrolysis of poly (d,l-lactide) in solution
Shih, C. (1995) · Journal of Controlled Release · doi:10.1016/0168-3659(94)00100-9 · Cited by 159 · see citing works
Mei, L., Bao, J., Tang, L., Zhang, C., Wang, H., Sun, L., Ma, G., Huang, L., Yang, J., Zhang, L., et al. (2010) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2010.01.012 · Cited by 36 · see citing works
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Biomaterials in Postoperative Adhesion Barriers and Uterine Tissue Engineering
Fazel Anvari-Yazdi, A., Badea, I., & Chen, X. (2025) · Gels · doi:10.3390/gels11060441 · Cited by 20 · see citing works
- Authors
- Lykins, W. R., Bernards, D. A., Schlesinger, E. B., Wisniewski, K., & Desai, T. A.
- Affiliations
- University of California, San Francisco (US)
- Corresponding author
- Desai, Tejal A.
- Venue
- Polymer
- Publisher
- Elsevier BV
- Published
- 2022-12
- Volume
- 262
- Pages
- 125473
- ISSN
- 0032-3861 (ISSN-L)
- OpenAlex
- W4308149936
- Cited by
- 34
- References
- 4
- Citations by year
- 2026: 13 · 2025: 10 · 2024: 8 · 2023: 2 · 2022: 1
- FWCI
- 1.31
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (am, 342 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Polymer (acceptedVersion)
- Funders
- National Science Foundation (1650113)
- NIH
- U.S. President’s Emergency Plan for AIDS Relief
- Topics
- Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
- Physical Sciences › Materials Science › Biomaterials › Magnesium Alloys: Properties and Applications
- Keywords
- polycaprolactone, polymer degradation, molecular weight, drug-eluting implants, biodegradable drug delivery, polymer films, mechanical properties, accelerated degradation testing, tissue engineering scaffolds
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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