Cited by 160biodegradable polymer synthesis and propertiesHydrogels: synthesis, properties, applicationsAdvanced Drug Delivery Systems

Chain-end scission in acid catalyzed hydrolysis of poly (d,l-lactide) in solution

Shih, Chung·1995·Journal of Controlled Release

Integrity signals

Registry

Crossref · 10.1016/0168-3659(94)00100-9

Cites

12 of 12 references verified0 citation errors · 0 not checkable

Statistics

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  • Although the two mechanisms operate simultaneously during hydrolysis, several studies have found that the chain-end scission is significantly faster than the random backbone cleavage.

    “Although the two mechanisms operate simultaneously during hydrolysis, several studies have found that the chainend scission is significantly faster than the random backbone cleavage.424,426,427”

    From Catalysis as an Enabling Science for Sustainable Polymers (2018) · cites this paper as [426]

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Authors
Shih, C.
Affiliations
Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
Corresponding author
Shih, Chung
Venue
Journal of Controlled Release
Publisher
Elsevier BV
Published
1995-04
Volume
34
Issue
1
Pages
9-15
ISSN
0168-3659 (ISSN-L)
OpenAlex
W2038798099
Cited by
159
References
13
Citations by year
2026: 5 · 2025: 8 · 2024: 7 · 2023: 2 · 2022: 11 · 2021: 8 · 2020: 4 · 2019: 5 · 2018: 2 · 2017: 6 · 2016: 3 · 2015: 5 · 2014: 6 · 2013: 6 · 2012: 6
FWCI
3.92
Type
journal article
Language
en
Open access
closed
Locations
Journal of Controlled Release (publishedVersion)
Topics
  • Physical Sciences › Materials Science › Biomaterials › biodegradable polymer synthesis and properties
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmaceutical Science › Advanced Drug Delivery Systems
Keywords
poly(D,L-lactide), acid hydrolysis, polymer degradation kinetics, polycaprolactone, deuterium labeling, autocatalysis

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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

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