The DOI matches its Crossref record; 428 of the 428 references it cites were found in a registry or an index.
Risk factors and biomarkers of age-related macular degeneration
Open accessAbstract
A biomarker can be a substance or structure measured in body parts, fluids or products that can affect or predict disease incidence. As age-related macular degeneration (AMD) is the leading cause of blindness in the developed world, much research and effort has been invested in the identification of different biomarkers to predict disease incidence, identify at risk individuals, elucidate causative pathophysiological etiologies, guide screening, monitoring and treatment parameters, and predict disease outcomes. To date, a host of genetic, environmental, proteomic, and cellular targets have been identified as both risk factors and potential biomarkers for AMD. Despite this, their use has been confined to research settings and has not yet crossed into the clinical arena. A greater understanding of these factors and their use as potential biomarkers for AMD can guide future research and clinical practice. This article will discuss known risk factors and novel, potential biomarkers of AMD in addition to their application in both academic and clinical settings.
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Cites
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Cited by
Age-related macular degeneration
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The blood–retina barrier in health and disease
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Metadata
- Authors
- Lambert, N. G., ElShelmani, H., Singh, M. K., Mansergh, F. C., Wride, M. A., Padilla, M., Keegan, D., Hogg, R. E., & Ambati, B. K.
- Venue
- Progress in Retinal and Eye Research
- Publisher
- Elsevier BV
- Published
- 2016-09
- Volume
- 54
- Pages
- 64-102
- ISSN
- 1350-9462 (ISSN-L)
- OpenAlex
- W2347205644
- Cited by
- 351
- References
- 428
- FWCI
- 27.65
- Type
- journal article
- Language
- en
- Open access
- green
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- Lambert, N. G., ElShelmani, H., Singh, M. K., Mansergh, F. C., Wride, M. A., Padilla, M., Keegan, D., Hogg, R. E., & Ambati, B. K. (2016). Risk factors and biomarkers of age-related macular degeneration. Progress in Retinal and Eye Research. https://doi.org/10.1016/j.preteyeres.2016.04.003
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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