The DOI matches its Crossref record; 78 of the 79 references it cites were found in a registry or an index.
Pharmacological Treatment of Obsessive-Compulsive Disorder
Open accessAbstract
Obsessive-compulsive disorder (OCD) affects up to 2.5% of the population of the course of a lifetime and produces substantial morbidity. Approximately 70% of patients can experience significant symptomatic relief with appropriate pharmacotherapy. Selective serotonin reuptake inhibitors are the mainstay of pharmacological treatment. These drugs are typically used at higher doses and for longer periods than in depression. Proven second-line treatments include the tricyclic clomipramine and the addition of low-dose neuroleptic medications. OCD refractory to available treatments remains a profound clinical challenge.
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“Since patients with OCD need higher doses of medication compared to other anxiety disorders, this lack of information may compromise the internal validity of this study [50].”
From Personalized exposure and experience sampling method feedback versus exposure as usual for obsessive–compulsive disorder: a study protocol for a randomized controlled trial (2024) · cites this paper as [50]
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Neuroscience-informed psychoeducation for OCD
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Metadata
- Authors
- Pittenger, C., & Bloch, M. H.
- Affiliations
- Yale University (US)
- Corresponding author
- Pittenger, Christopher
- Venue
- Psychiatric Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2014-09
- Volume
- 37
- Issue
- 3
- Pages
- 375-391
- ISSN
- 0193-953X (ISSN-L)
- PMC
- PMC4143776
- OpenAlex
- W1997452831
- Cited by
- 222
- References
- 79
- Citations by year
- 2026: 24 · 2025: 25 · 2024: 31 · 2023: 32 · 2022: 21 · 2021: 16 · 2020: 17 · 2019: 16 · 2018: 8 · 2017: 7 · 2016: 12 · 2015: 10 · 2014: 1
- FWCI
- 1.52
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Psychiatric Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (UL1TR000142)
- National Institute of Mental Health (R01MH095790, R34MH083115, K23MH091240, R25MH077823)
- National Center for Advancing Translational Sciences
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- obsessive-compulsive disorder, pharmacotherapy, selective serotonin reuptake inhibitors, clomipramine, tricyclic antidepressants, treatment-resistant OCD, second-line therapy
- MeSH terms
- Combined Modality Therapy, Drug Therapy, Combination, Nonprescription Drugs, Humans, Obsessive-Compulsive Disorder, Psychotherapy, Psychotropic Drugs, Precision Medicine
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