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A joint ESTRO and AAPM guideline for development, clinical validation and reporting of artificial intelligence models in radiation therapy
Open accessAbstract
BACKGROUND AND PURPOSE: Artificial Intelligence (AI) models in radiation therapy are being developed with increasing pace. Despite this, the radiation therapy community has not widely adopted these models in clinical practice. A cohesive guideline on how to develop, report and clinically validate AI algorithms might help bridge this gap. METHODS AND MATERIALS: A Delphi process with all co-authors was followed to determine which topics should be addressed in this comprehensive guideline. Separate sections of the guideline, including Statements, were written by subgroups of the authors and discussed with the whole group at several meetings. Statements were formulated and scored as highly recommended or recommended. RESULTS: The following topics were found most relevant: Decision making, image analysis, volume segmentation, treatment planning, patient specific quality assurance of treatment delivery, adaptive treatment, outcome prediction, training, validation and testing of AI model parameters, model availability for others to verify, model quality assurance/updates and upgrades, ethics. Key references were given together with an outlook on current hurdles and possibilities to overcome these. 19 Statements were formulated. CONCLUSION: A cohesive guideline has been written which addresses main topics regarding AI in radiation therapy. It will help to guide development, as well as transparent and consistent reporting and validation of new AI tools and facilitate adoption.
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“Acceptance testing of AI auto contouring algorithms typically involves both area‐based metrics (e.g., Dice Similarity Coefficient, Intersection over Union (IoU)) and distance‐based metrics (e.g., Hausdorff Distance) evaluated against reference standard contours. 11 , 12 , 13 , 14 These metrics are well established for assessing contour agreement, but they say nothing about where the model is confi”
From Uncertainty quantification of U‐Net based segmentation tool using conformal prediction (2026) · cites this paper as [11]
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Cites
The Nature of Statistical Learning Theory
Vapnik, V. (2000) · Statistics for Engineering and Information Science · doi:10.1007/978-1-4757-3264-1 · Cited by 46,387
PROBAST: A Tool to Assess the Risk of Bias and Applicability of Prediction Model Studies
Wolff, R. F., Moons, K. G. M., Riley, R. D., Whiting, P. F., Westwood, M., Collins, G. S., Reitsma, J. B., Kleijnen, J., Mallett, S., & for the PROBAST Group† (2019) · Annals of Internal Medicine · doi:10.7326/m18-1376 · Cited by 2,984
Checklist for Artificial Intelligence in Medical Imaging (CLAIM): a guide for authors and reviewers
Mongan, J., Moy, L., & Kahn, C. E. (2020) · Radiology: Artificial Intelligence · doi:10.1148/ryai.2020200029 · Cited by 1,443
Vasey, B., Nagendran, M., Campbell, B., Clifton, D. A., Collins, G. S., Denaxas, S., Denniston, A. K., Faes, L., Geerts, B., Ibrahim, M., et al. (2022) · Nature Medicine · doi:10.1038/s41591-022-01772-9 · Cited by 1,039
Self-citationCruz Rivera, S., Liu, X., Chan, A.-W., Denniston, A. K., Calvert, M. J., The SPIRIT-AI and CONSORT-AI Working Group, SPIRIT-AI and CONSORT-AI Steering Group, Darzi, A., Holmes, C., Yau, C., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1037-7 · Cited by 933
Collins, G. S., Dhiman, P., Andaur Navarro, C. L., Ma, J., Hooft, L., Reitsma, J. B., Logullo, P., Beam, A. L., Peng, L., Van Calster, B., et al. (2021) · BMJ Open · doi:10.1136/bmjopen-2020-048008 · Cited by 852
Reporting of artificial intelligence prediction models
Collins, G. S., & Moons, K. G. M. (2019) · The Lancet · doi:10.1016/s0140-6736(19)30037-6 · Cited by 701
Minimum information about clinical artificial intelligence modeling: the MI-CLAIM checklist.
Norgeot, B., Quer, G., Beaulieu-Jones, B. K., Torkamani, A., Dias, R., Gianfrancesco, M., Arnaout, R., Kohane, I. S., Saria, S., Topol, E., et al. (2020) · Nature Medicine · doi:10.1038/s41591-020-1041-y · Cited by 665
Vollmer, S. J., Mateen, B. A., Bohner, G., Király, F. J., Ghani, R., Jonsson, P. F., Cumbers, S., Jonas, A., McAllister, K., Myles, P. R., et al. (2020) · BMJ · doi:10.1136/bmj.l6927 · Cited by 574
Langendijk, J. A., Lambin, P., Ruysscher, D. D., Widder, J., Bos, M., & Verheij, M. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.05.007 · Cited by 559
Liu, X., Cruz Rivera, S., Moher, D., Calvert, M. J., Denniston, A. K., Ashrafian, H., Beam, A. L., Chan, A.-W., Collins, G. S., Deeks, A. D. J., et al. (2020) · The Lancet Digital Health · doi:10.1016/s2589-7500(20)30218-1 · Cited by 555
Collins, G. S., Reitsma, J. B., Altman, D. G., & Moons, K. G. M. (2015) · Annals of Internal Medicine · doi:10.7326/l15-5093-2 · Cited by 493
(1996) · Journal of Clinical Oncology · doi:10.1200/jco.1996.14.2.671 · Cited by 430
Hernandez-Boussard, T., Bozkurt, S., Ioannidis, J. P. A., & Shah, N. H. (2020) · Journal of the American Medical Informatics Association · doi:10.1093/jamia/ocaa088 · Cited by 410
Rapid-Learning System for Cancer Care
Abernethy, A. P., Etheredge, L. M., Ganz, P. A., Wallace, P., German, R. R., Neti, C., Bach, P. B., & Murphy, S. B. (2010) · Journal of Clinical Oncology · doi:10.1200/jco.2010.28.5478 · Cited by 366
Vandewinckele, L., Claessens, M., Dinkla, A. M., Brouwer, C. L., Crijns, W., Verellen, D., & van Elmpt, W. (2020) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2020.09.008 · Cited by 341
MR fingerprinting Deep RecOnstruction NEtwork (DRONE)
Cohen, O., Zhu, B., & Rosen, M. S. (2018) · Magnetic Resonance in Medicine · doi:10.1002/mrm.27198 · Cited by 310
Human–machine partnership with artificial intelligence for chest radiograph diagnosis
Patel, B. N., Rosenberg, L., Willcox, G., Baltaxe, D., Lyons, M., Irvin, J., Rajpurkar, P., Amrhein, T., Gupta, R., Halabi, S., et al. (2019) · npj Digital Medicine · doi:10.1038/s41746-019-0189-7 · Cited by 254
ESTRO-EANO guideline on target delineation and radiotherapy details for glioblastoma
Niyazi, M., Andratschke, N. H., Bendszus, M., Chalmers, A. J., Erridge, S., Galldiks, N., Lagerwaard, F. J., Navarria, P., af Rosenschöld, P. M., Ricardi, U., et al. (2023) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2023.109663 · Cited by 237
Mayo, C. S., Moran, J. M., Bosch, W. R., Xiao, Y., McNutt, T., Popple, R. A., Michalski, J. M., Feng, M. U.-S., Marks, L. B., Fuller, C. D., et al. (2017) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2017.12.013 · Cited by 213
Self-citationDeep learning in head & neck cancer outcome prediction
Diamant, A., Chatterjee, A., Vallières, M., Shenouda, G., & Seuntjens, J. P. (2019) · Scientific Reports · doi:10.1038/s41598-019-39206-1 · Cited by 211
Self-citationHernández, V., Hansen, C. R., Widesott, L., Bäck, A., Canters, R. A. M., Fusella, M., Götstedt, J., Jurado‐Bruggeman, D., Mukumoto, N., Kaplan, L. P., et al. (2020) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2020.09.038 · Cited by 210
McIntosh, C., Conroy, L., Tjong, M. C., Craig, T., Bayley, A., Catton, C., Gospodarowicz, M. K., Helou, J. A., Isfahanian, N., Kong, V., et al. (2021) · Nature Medicine · doi:10.1038/s41591-021-01359-w · Cited by 196
4π Non-Coplanar Liver SBRT: A Novel Delivery Technique
Dong, P., Lee, P. P., Ruan, D., Long, T., Romeijn, H. E., Yang, Y., Low, D. A., Kupelian, P. A., & Sheng, K. (2012) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2012.09.028 · Cited by 165
Ahmed, K. A., Caudell, J. J., El-Haddad, G. E., Berglund, A., Welsh, E. A., Yue, B., Hoffe, S. E., Naghavi, A. O., Abuodeh, Y. A., Frakes, J. M., et al. (2016) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2016.03.050 · Cited by 162
Introduction to machine and deep learning for medical physicists
Cui, S., Tseng, H., Pakela, J. M., Haken, R. K. T., & Naqa, I. E. (2020) · Medical Physics · doi:10.1002/mp.14140 · Cited by 133
A review of explainable and interpretable AI with applications in COVID‐19 imaging
Fuhrman, J. D., Gorre, N., Hu, Q., Li, H., Naqa, I. E., & Giger, M. L. (2021) · Medical Physics · doi:10.1002/mp.15359 · Cited by 124
Luo, Y., Tseng, H.-H., Cui, S., Wei, L., Haken, R. K. T., & Naqa, I. E. (2019) · BJR|Open · doi:10.1259/bjro.20190021 · Cited by 118
Automated Contouring and Planning in Radiation Therapy: What Is ‘Clinically Acceptable’?
Baroudi, H., Brock, K. K., Cao, W., Chen, X., Chung, C. D., Court, L. E., Basha, M. D. E., Farhat, M., Gay, S., Gronberg, M., et al. (2023) · Diagnostics · doi:10.3390/diagnostics13040667 · Cited by 112
Self-citationRusanov, B., Hassan, G. M., Reynolds, M. A., Sabet, M., Kendrick, J., Rowshanfarzad, P., & Ebert, M. A. (2022) · Medical Physics · doi:10.1002/mp.15840 · Cited by 104
Requirements and reliability of AI in the medical context
Balagurunathan, Y., Mitchell, R., & Naqa, I. E. (2021) · Physica Medica · doi:10.1016/j.ejmp.2021.02.024 · Cited by 94
AI and machine learning ethics, law, diversity, and global impact
Drabiak, K., Kyzer, S., Nemov, V., & El Naqa, I. (2023) · The British Journal of Radiology · doi:10.1259/bjr.20220934 · Cited by 84
A machine learning approach to the accurate prediction of multi-leaf collimator positional errors
Carlson, J., Park, J. M., Park, S. Y., Park, J. M., Choi, Y., & Ye, S. (2016) · Physics in Medicine and Biology · doi:10.1088/0031-9155/61/6/2514 · Cited by 83
Hosny, A., Bitterman, D. S., Guthier, C. V., Qian, J. M., Roberts, H. J., Perni, S., Saraf, A., Peng, L. C., Pashtan, I. M., Ye, Z., et al. (2022) · The Lancet Digital Health · doi:10.1016/s2589-7500(22)00129-7 · Cited by 74
Li, X., Zhang, J., Sheng, Y., Chang, Y., Yin, F.-F., Ge, Y., Wu, Q., & Wang, C. (2020) · Physics in Medicine and Biology · doi:10.1088/1361-6560/aba5eb · Cited by 68
Scott, J. G., Sedor, G., Scarborough, J. A., Kattan, M. W., Peacock, J. S., Grass, G. D., Mellon, E. A., Thapa, R., Schell, M. J., Waller, A. F., et al. (2020) · Journal of Thoracic Oncology · doi:10.1016/j.jtho.2020.11.008 · Cited by 65
Deep learning in magnetic resonance image reconstruction
Chandra, S. S., Lorenzana, M. B., Liu, X., Liu, S., Bollmann, S., & Crozier, . (2021) · Journal of Medical Imaging and Radiation Oncology · doi:10.1111/1754-9485.13276 · Cited by 64
Applications of machine and deep learning to patient‐specific IMRT/VMAT quality assurance
Osman, A. F. I., & Maalej, N. M. (2021) · Journal of Applied Clinical Medical Physics · doi:10.1002/acm2.13375 · Cited by 64
Artificial Intelligence for Optimization and Interpretation of PET/CT and PET/MR Images
Zaharchuk, G., & Davidzon, G. (2020) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2020.10.001 · Cited by 61
Wootton, L. S., Nyflot, M. J., Chaovalitwongse, W. A., & Ford, E. (2018) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2018.05.033 · Cited by 59
Kawula, M., Hadi, I., Nierer, L., Vagni, M., Cusumano, D., Boldrini, L., Placidi, L., Corradini, S., Belka, C., Landry, G., et al. (2022) · Medical Physics · doi:10.1002/mp.16056 · Cited by 55
Self-citationNguyen, D. T. D., Barkousaraie, A. S., Bohara, G., Balagopal, A., McBeth, R., Lin, M., & Jiang, S. B. (2021) · Physics in Medicine and Biology · doi:10.1088/1361-6560/abe04f · Cited by 54
Advances in Automated Treatment Planning
Nguyen, D. T. D., Lin, M., Sher, D. J., Lu, W., Jia, X., & Jiang, S. B. (2022) · Seminars in Radiation Oncology · doi:10.1016/j.semradonc.2022.06.004 · Cited by 53
Real-time motion management in MRI-guided radiotherapy: Current status and AI-enabled prospects
Lombardo, E., Dhont, J., Page, D., Garibaldi, C., Künzel, L. A., Hurkmans, C., Tijssen, R. H. N., Paganelli, C., Liu, P. Z. Y., Keall, P., et al. (2023) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2023.109970 · Cited by 52
Self-citationBrady, A. P., Allen, B., Chong, J., Kotter, E., Kottler, N. E., Mongan, J., Oakden‐Rayner, L., dos Santos, D. P., Tang, A., Wald, C., et al. (2024) · Journal of Medical Imaging and Radiation Oncology · doi:10.1111/1754-9485.13612 · Cited by 50
Brouwer, C. L., Djamal Boukerroui, A., Oliveira, J., Looney, P., Steenbakkers, R. J. H. M., Langendijk, J. A., Both, S., & Gooding, M. J. (2020) · Physics and Imaging in Radiation Oncology · doi:10.1016/j.phro.2020.10.001 · Cited by 50
Kiser, K. J., Barman, A., Stieb, S., Fuller, C. D., & Giancardo, L. (2021) · Journal of Imaging Informatics in Medicine · doi:10.1007/s10278-021-00460-3 · Cited by 49
Mayo, C. S., Feng, M. U.-S., Brock, K. K., Kudner, R., Balter, P. A., Buchsbaum, J. C., Caissie, A. L., Covington, E. L., Daugherty, E. C., Dekker, A. L. A. J., et al. (2023) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2023.05.033 · Cited by 47
Self-citationPatient-specific daily updated deep learning auto-segmentation for MRI-guided adaptive radiotherapy
Li, Z., Zhang, W., Li, B., Zhu, J., Peng, Y., Li, C., Zhu, J. Y., Zhou, Q., & Yin, Y. (2022) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2022.11.004 · Cited by 47
Fast contour propagation for MR‐guided prostate radiotherapy using convolutional neural networks
Eppenhof, K. A. J., Maspero, M., Savenije, M. H. F., de Boer, J. C. J., van Zyp, J. R. N. V. D. V., Raaymakers, B. W., Raaijmakers, A. J. E., Veta, M., van den Berg, C. A. T., & Pluim, J. P. W. (2019) · Medical Physics · doi:10.1002/mp.13994 · Cited by 46
Gugliandolo, S. G., Pepa, M., Isaksson, L. J., Marvaso, G., Raimondi, S., Botta, F., Gandini, S., Ciardo, D., Volpe, S., Riva, G., et al. (2020) · European Radiology · doi:10.1007/s00330-020-07105-z · Cited by 44
Self-citationAI in medical physics: guidelines for publication
Naqa, I. E., Boone, J. M., Benedict, S., Goodsitt, M. M., Chan, H., Drukker, K., Hadjiiski, L. M., Ruan, D., & Sahiner, B. (2021) · Medical Physics · doi:10.1002/mp.15170 · Cited by 43
Jabbarpour, A., Mahdavi, S. R., Sadr, A. V., Esmaili, G., Shiri, I., & Zaidi, H. (2022) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2022.105277 · Cited by 43
HYDRA: Hybrid deep magnetic resonance fingerprinting
Song, P., Eldar, Y. C., Mazor, G., & Rodrigues, M. R. D. (2019) · Medical Physics · doi:10.1002/mp.13727 · Cited by 37
Chuang, K., Giles, W., & Adamson, J. D. (2020) · Medical Physics · doi:10.1002/mp.14670 · Cited by 37
Barkousaraie, A. S., Ogunmolu, O., Jiang, S. B., & Nguyen, D. T. D. (2019) · Medical Physics · doi:10.1002/mp.13986 · Cited by 35
Machine and Deep Learning in Oncology, Medical Physics and Radiology
(2022) · Springer eBooks · doi:10.1007/978-3-030-83047-2 · Cited by 35
Chen, X., Ma, X., Yan, X., Luo, F., Yang, S., Wang, Z., Wu, R., Wang, J., Lu, N., Bi, N., et al. (2022) · Medical Physics · doi:10.1002/mp.15793 · Cited by 34
Kimura, Y., Kadoya, N., Oku, Y., Kajikawa, T., Tomori, S., & Jingu, K. (2021) · Medical Physics · doi:10.1002/mp.15031 · Cited by 33
A review of artificial intelligence applications for motion tracking in radiotherapy
Mylonas, A., Booth, J., & Nguyen, D. T. (2021) · Journal of Medical Imaging and Radiation Oncology · doi:10.1111/1754-9485.13285 · Cited by 30
Lessons learned in transitioning to AI in the medical imaging of COVID-19
Naqa, I. M. E., Hu, Q., Chen, W., Li, H., Fuhrman, J. D., Gorre, N., & Giger, M. L. (2021) · Journal of medical imaging · doi:10.1117/1.jmi.8.s1.010902 · Cited by 30
Kang, J., Thompson, R. F., Aneja, S., Lehman, C., Trister, A., Zou, J., Obcemea, C., & El Naqa, I. (2021) · Practical Radiation Oncology · doi:10.1016/j.prro.2020.06.001 · Cited by 30
Fransson, S., Tilly, D., & Strand, R. (2022) · Physics and Imaging in Radiation Oncology · doi:10.1016/j.phro.2022.06.001 · Cited by 29
Deep learning driven predictive treatment planning for adaptive radiotherapy of lung cancer
Lee, D., Hu, Y., Kuo, L., Alam, S. R., Yorke, E. D., Li, A., Rimner, A., & Zhang, P. (2022) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2022.02.013 · Cited by 29
Eriksson, O., & Zhang, T. (2022) · Medical Physics · doi:10.1002/mp.15622 · Cited by 28
Yuan, Z., Wang, Y., Hu, P., Zhang, D., Yan, B., Lu, H., Zhang, H., & Yang, Y. (2022) · Medical Physics · doi:10.1002/mp.15530 · Cited by 24
Uncertainty-guided man–machine integrated patient-specific quality assurance
Yang, X., Li, S., Shao, Q., Cao, Y. S., Yang, Z., & Zhao, Y. (2022) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2022.05.016 · Cited by 24
ESTRO ACROP guideline on prostate bed delineation for postoperative radiotherapy in prostate cancer
Pra, A. D., Dirix, P. R., Khoo, V. S., Carrié, C., Cozzarini, C., Fonteyne, V., Ghadjar, P., Iturriaga, A. G., Panebianco, V., Zapatero, A., et al. (2023) · Clinical and Translational Radiation Oncology · doi:10.1016/j.ctro.2023.100638 · Cited by 23
Prospective clinical deployment of machine learning in radiation oncology
Naqa, I. E. (2021) · Nature Reviews Clinical Oncology · doi:10.1038/s41571-021-00541-w · Cited by 22
Clinical evaluation of two AI models for automated breast cancer plan generation
Kneepkens, E., Bakx, N., van der Sangen, M., Theuws, J. C. M., van der Toorn, P.-P., Rijkaart, D., van der Leer, J., van Nunen, T., Hagelaar, E., Bluemink, H., et al. (2022) · Radiation Oncology · doi:10.1186/s13014-022-01993-9 · Cited by 21
Self-citationA comprehensive survey on deep learning techniques in CT image quality improvement
Li, D., Ma, L., Li, J., Qi, S., Yao, Y., & Teng, Y. (2022) · Medical & Biological Engineering & Computing · doi:10.1007/s11517-022-02631-y · Cited by 19
Huang, Y., Pi, Y., Ma, K., Miao, X., Fu, S., Zhu, Z., Cheng, Y., Zhang, Z., Chen, H., Wang, H., et al. (2022) · Technology in Cancer Research & Treatment · doi:10.1177/15330338221104881 · Cited by 19
Luo, Y., Jolly, S., Palma, D. A., Lawrence, T. S., Tseng, H.-H., Valdés, G., McShan, D. L., Haken, R. K. T., & Naqa, I. E. (2021) · Physica Medica · doi:10.1016/j.ejmp.2021.05.032 · Cited by 19
Hussein, M., Clementel, E., Eaton, D. J., Greer, P. B., Haworth, A., Ishikura, S., Kry, S. F., Lehmann, J., Lye, J., Monti, A. F., et al. (2017) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2017.10.012 · Cited by 18
Self-citationMayo, C. S., Mierzwa, M. L., Yalamanchi, P., Evans, J. R., Worden, F. P., Medlin, R. P., Schipper, M. J., Schonewolf, C. A., Shah, J. L., Spector, M. E., et al. (2023) · JCO Clinical Cancer Informatics · doi:10.1200/cci.22.00037 · Cited by 12
Self-citationThor, M., Oh, J. H., Apte, A., & Deasy, J. O. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00978 · Cited by 10
Gong, C., Zhu, K., Lin, C., Han, C., Lu, Z., Chen, Y., Yu, C., Hou, L., Zhou, Y., Yi, J., et al. (2022) · Medical Physics · doi:10.1002/mp.16010 · Cited by 9
Chen, A., Chen, F., Li, X., Zhang, Y., Chen, L., Chen, L., & Zhu, J. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.908903 · Cited by 8
Ni, Y., Chen, S., Hibbard, L. S., & Voet, P. W. J. (2022) · Physics in Medicine and Biology · doi:10.1088/1361-6560/ac80e5 · Cited by 8
Matsuura, T., Kawahara, D., Saito, A., Miura, H., Yamada, K., Ozawa, S., & Nagata, Y. (2022) · Physical and Engineering Sciences in Medicine · doi:10.1007/s13246-022-01172-w · Cited by 6
Wolfs, C. J. A., Varfalvy, N., Canters, R. A. M., Nijsten, S. M. J. J. G., Hattu, D., Archambault, L., & Verhaegen, F. (2020) · Medical Physics · doi:10.1002/mp.14385 · Cited by 6
Bakx, N., van der Sangen, M., Theuws, J. C. M., Bluemink, H., & Hurkmans, C. (2023) · Technical Innovations & Patient Support in Radiation Oncology · doi:10.1016/j.tipsro.2023.100209 · Cited by 5
Self-citationChun, J., Park, J. C., Olberg, S., Zhang, Y., Nguyen, D. T. D., Wang, J., Kim, J. S., & Jiang, S. B. (2021) · Medical Physics · doi:10.1002/mp.15352 · Cited by 4
Research works printed but not linked: 6
- Fda, 2019, Proposed regulatory framework for modifications to artificial intelligence/machine learning (AI/ML)- based software as a medical device (SaMD). Food and Drug, Administration
- Holmes, 2023, Evaluating Large Language Models on a Highly-specialized Topic, Radiation Oncology Physics. Front, Oncol, 17, 1219326
- Huang, 2021, Virtual Patient-Specific Quality Assurance of IMRT Using UNet++: Classification, Gamma Passing Rates Prediction, and Dose Difference Prediction. Front, Oncol, %20;11
- Liu, Z, Wang, P, Li, Y, Holmes, J, Shu, P, Zhang, L, Liu, C, Liu, N, Zhu, D, Li, X, Li, Q, Patel, S. H., Sio, T. T, Liu, T, Liu, W. RadOnc-GPT: A Large Language Model for Radiation Oncology. arXiv:2309.10160 webpage visited 6-11-2023. · arXiv
- Prunaretty, 2023, A multi-centric evaluation of self-learning GAN based pseudo-CT generation software for low field pelvic magnetic resonance imaging. Front, Oncol, 13, 1245054
- van de, 2021, Artificial intelligence based treatment planning of radiotherapy for locally advanced breast cancer. Phys Imaging, Radiat Oncol, 20, 111
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Mastella, E., Calderoni, F., Manco, L., Ferioli, M., Medoro, S., Turra, A., Giganti, M., & Stefanelli, A. (2025) · Physics and Imaging in Radiation Oncology · doi:10.1016/j.phro.2025.100731 · Cited by 31
Rusanov, B., Ebert, M. A., Sabet, M., Rowshanfarzad, P., Barry, N., Kendrick, J., Alkhatib, Z., Gill, S., Dass, J., Bucknell, N. W., et al. (2025) · Physical and Engineering Sciences in Medicine · doi:10.1007/s13246-024-01513-x · Cited by 21
Giordano, A., Romero-Mascarell, C., González-Suárez, B., & Guarner‐Argente, C. (2025) · Digestive Diseases and Sciences · doi:10.1007/s10620-025-09099-4 · Cited by 13
Carriero, S., Cannella, R., Cicchetti, F., Angileri, S. A., Bruno, A., Biondetti, P., Colciago, R. R., D’Antonio, A., Pepa, G. D., Grassi, F., et al. (2025) · Journal of Medical Imaging and Radiation Oncology · doi:10.1111/1754-9485.13880 · Cited by 16
Metadata
- Authors
- Hurkmans, C., Bibault, J.-E., Brock, K. K., van Elmpt, W., Feng, M., David Fuller, C., Jereczek-Fossa, B. A., Korreman, S., Landry, G., Madesta, F., Mayo, C., McWilliam, A., Moura, F., Muren, L. P., El Naqa, I., Seuntjens, J., Valentini, V., & Velec, M.
- Affiliations
- Catharina Ziekenhuis (NL)
- Hôpital Européen Georges-Pompidou (FR)
- The University of Texas MD Anderson Cancer Center (US)
- Maastricht University Medical Centre (NL)
- University of California, San Francisco (US)
- Aarhus University (DK)
- LMU Klinikum (DE)
- University Medical Center Hamburg-Eppendorf (DE)
- University of Michigan (US)
- University of Manchester (GB)
- University Health Network (CA)
- Università Cattolica del Sacro Cuore (IT)
- University of Toronto (CA)
- Corresponding author
- Hurkmans, Coen
- ORCID
- Venue
- Radiotherapy and Oncology
- Publisher
- Elsevier BV
- Published
- 2024-08
- Volume
- 197
- Pages
- 110345
- ISSN
- 0167-8140 (ISSN-L)
- OpenAlex
- W4399327635
- Cited by
- 110
- References
- 85
- Citations by year
- 2026: 56 · 2025: 46 · 2024: 7
- FWCI
- 10.19
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Radiotherapy and Oncology (publishedVersion, cc-by)
- PubMed (publishedVersion)
- TU/e Research Portal (publishedVersion, cc-by)
- Digital Commons-TMC (Texas Medical Center) (submittedVersion)
- Research Publications (Maastricht University) (submittedVersion, cc-by)
- Funders
- European SocieTy for Radiotherapy and Oncology
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Physics and Astronomy › Radiation › Advanced Radiotherapy Techniques
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiomics and Machine Learning in Medical Imaging
- Keywords
- artificial intelligence, radiotherapy, treatment planning, adaptive radiotherapy, image segmentation, patient-specific quality assurance, outcome prediction, AI ethics, clinical adoption of AI, Delphi consensus
- MeSH terms
- Algorithms, Artificial Intelligence, Delphi Technique, Humans, Radiotherapy, Radiotherapy Planning, Computer-Assisted, Radiation Oncology
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Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
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