The DOI matches its Crossref record; 153 of the 153 references it cites were found in a registry or an index.
Oxidative stress pathways of air pollution mediated toxicity: Recent insights
Open accessAbstract
Ambient air pollution is a leading environmental cause of morbidity and mortality globally with most of the outcomes of cardiovascular origin. While numerous mechanisms are proposed to explain the link between air pollutants and cardiovascular events, the evidence supports a role for oxidative stress as a critical intermediary pathway in the transduction of systemic responses in the cardiovascular system. Indeed, alterations in vascular function are a critical step in the development of cardiometabolic disorders such as hypertension, diabetes, and atherosclerosis. This review will provide an overview of the impact of particulate and gaseous pollutants on oxidative stress from human and animal studies published in the last five years. We discuss current gaps in knowledge and evidence to date implicating the role of oxidative stress with an emphasis on inhalational exposures. We conclude with the identification of gaps, and an exhortation for further studies to elucidate the impact of oxidative stress in air pollution mediated effects.
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Cites
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Advanced human developmental toxicity and teratogenicity assessment using human organoid models
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Prenatal Ambient Ultrafine Particle Exposure and Childhood Asthma in the Northeastern United States
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Airways Type-2 Related Disorders: Multiorgan, Systemic or Syndemic Disease?
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Metadata
- Authors
- Gangwar, R. S., Bevan, G. H., Palanivel, R., Das, L., & Rajagopalan, S.
- Venue
- Redox Biology
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 34
- Pages
- 101545
- ISSN
- 2213-2317 (ISSN-L)
- OpenAlex
- W3027341006
- Cited by
- 409
- References
- 153
- FWCI
- 13.27
- Type
- journal article
- Language
- en
- Open access
- gold
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- Gangwar, R. S., Bevan, G. H., Palanivel, R., Das, L., & Rajagopalan, S. (2020). Oxidative stress pathways of air pollution mediated toxicity: Recent insights. Redox Biology. https://doi.org/10.1016/j.redox.2020.101545
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