The DOI matches its Crossref record; 186 of the 186 references it cites were found in a registry or an index.
The vagus nerve, food intake and obesity
Open accessAbstract
Food interacts with sensors all along the alimentary canal to provide the brain with information regarding its composition, energy content, and beneficial effect. Vagal afferents innervating the gastrointestinal tract, pancreas, and liver provide a rapid and discrete account of digestible food in the alimentary canal, as well as circulating and stored fuels, while vagal efferents, together with the sympathetic nervous system and hormonal mechanisms, codetermine the rate of nutrient absorption, partitioning, storage, and mobilization. Although vagal sensory mechanisms play a crucial role in the neural mechanism of satiation, there is little evidence suggesting a significant role in long-term energy homeostasis. However, increasing recognition of vagal involvement in the putative mechanisms making bariatric surgeries the most effective treatment for obesity should greatly stimulate future research to uncover the many details regarding the specific transduction mechanisms in the periphery and the inter- and intra-neuronal signaling cascades disseminating vagal information across the neuraxis.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“They influence the control of food intake and regulation of satiety, gastric emptying and energy balance (39) by transmitting signals arising from the upper gut to the nucleus of the solitary tract in the brain (40).”
From Vagus Nerve as Modulator of the Brain–Gut Axis in Psychiatric and Inflammatory Disorders (2018) · cites this paper as [39]
In the citing paper
“selective vagotomy by itself fails to affect energy homeostasis (19).”
From Leptin and the Central Nervous System Control of Glucose Metabolism (2011) · cites this paper as [19]
In the citing paper
“abundant evidence suggests that vagal afferents play a critical role in the ability of gut-derived satiety signals, such as CCK, to promote the termination of a meal”
From Leptin and the Central Nervous System Control of Glucose Metabolism (2011) · cites this paper as [19]
Citations
Cites
Martin, R. (1986) · Medical Entomology and Zoology · Cited by 8,752
Neurons containing hypocretin (orexin) project to multiple neuronal systems
Peyron, C., Tighe, D. K., van den Pol, A. N., de Lecea, L., Heller, H. C., Sutcliffe, J. G., & Kilduff, T. S. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-23-09996.1998 · Cited by 3,466
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
Cummings, D. E., Purnell, J. Q., Frayo, R. S., Schmidova, K., Wisse, B. E., & Weigle, D. S. (2001) · Diabetes · doi:10.2337/diabetes.50.8.1714 · Cited by 2,940
Gut hormone PYY3-36 physiologically inhibits food intake
Batterham, R. L., Cowley, M. A., Small, C. J., Herzog, H., Cohen, M. A., Dakin, C. L., Wren, A. M., Brynes, A. E., Low, M. J., Ghatei, M. A., et al. (2002) · Nature · doi:10.1038/nature00887 · Cited by 2,351
Ricardo, J. A., & Koh, E. T. (1978) · Brain Research · doi:10.1016/0006-8993(78)91125-3 · Cited by 1,362
Functional and chemical anatomy of the afferent vagal system
Berthoud, H.-R., & Neuhuber, W. L. (2000) · Autonomic Neuroscience · doi:10.1016/s1566-0702(00)00215-0 · Cited by 1,280
Self-citationThe stomach is a source of leptin
Bado, A., Levasseur, S., Attoub, S., Kermorgant, S., Laigneau, J., Bortoluzzi, M.-N., Moizo, L., Lehy, T., Guerre-Millo, M., MARCHAND‐BRUSTEL, Y. L., et al. (1998) · Nature · doi:10.1038/29547 · Cited by 1,242
Handbook of behavioral neurobiology
Blass, E. M. (1988) · Plenum Press eBooks · Cited by 1,122
Date, Y., Murakami, N., Toshinai, K., Matsukura, S., Niijima, A., Matsuo, H., Kangawa, K., & Nakazato, M. (2002) · Gastroenterology · doi:10.1053/gast.2002.35954 · Cited by 1,099
Bittencourt, J. C., Presse, F., Arias, C. M., Peto, C. A., Vaughan, J. M., Nahon, J., Vale, W., & Sawchenko, P. E. (1992) · The Journal of Comparative Neurology · doi:10.1002/cne.903190204 · Cited by 1,075
Flagged first, then by citations
Cited by
Sorted by citations
Items 301–314 of 314
A vagal gut-brain axis for feeding induced gastric secretionPreprint
Wang, Z., Tang, Q., Li, K., Li, J., Mou, J., Sun, X., Wei, Y., Chen, Y., Guo, P., Jin, L., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.03.01.708884
Gut-brain axis in metabolic control
Singh, S. P., Ghosh, S., Singh, D. K. K., & Sinha, J. K. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-32848-0.00024-8
Khlaifia, A. (2015) · theses.fr (ABES) · doi:10.70675/48826ff3zef5bz49d0z8389z57ab7666f35b
The Microbiome-Body Connection: Unraveling the Gut-Brain Axis
Islam, M. M., Mahbub, N. U., & Islam, M. A. (2026) · Springer eBooks · doi:10.1007/978-981-95-7494-0_1
Fekri-Kourabbaslou, V., Amirsasan, R., & Nikoukheslat, S. D. (2026) · Health Science Reports · doi:10.1002/hsr2.72204
Zhang, A.-Y., Guo, Z.-H., Huang, Y., Shi, Y.-R., Song, X., Wang, S.-Y., Yang, G.-H., Liu, Y., & Xu, T.-C. (2026) · World Journal of Transplantation · doi:10.5500/wjt.v16.i2.118169
The vagus nerve as a neurovisceral interface: a comprehensive review
In, S.-Y., Cho, T., & Yang, H. (2026) · Frontiers in Neuroscience · doi:10.3389/fnins.2026.1878765
Paraventricular thalamic neurons respond to vagus nerve activation and modulate anxious behavior
Xie, Z., Yamakawa, M., Kayama, T., Sasaki, T., & Kuga, N. (2026) · Frontiers in Neural Circuits · doi:10.3389/fncir.2026.1865790
Jia, K., Liu, Y., Zhang, Y., Bai, L., Zhang, L., Xie, F., Yan, X., Xu, J., & Liao, K. (2026) · Journal of Biological Chemistry · doi:10.1016/j.jbc.2026.113515
Awakening the Vagus: Transcutaneous Auricular Vagus Nerve Stimulation—A Narrative Review
Portincaso, L., Santi, G. C., Villa, N., & Pietro, D. A. D. (2026) · Brain Sciences · doi:10.3390/brainsci16090979
A vagal gut-brain axis for feeding-induced gastric secretion in mice
Wang, Z., Tang, Q., Li, K., Li, J., Mou, J., Sun, X., Wei, Y., Chen, Y., Guo, P., Jin, L., et al. (2026) · Neuron · doi:10.1016/j.neuron.2026.09.033
Wasse, L. K. (2011) · Loughborough University Institutional Repository (Loughborough University)
Metadata
- Authors
- Berthoud, H.-R.
- Affiliations
- Pennington Biomedical Research Center (US)
- Corresponding author
- Berthoud, Hans-Rudolf
- Venue
- Regulatory Peptides
- Publisher
- Elsevier BV
- Published
- 2008-08
- Volume
- 149
- Issue
- 1-3
- Pages
- 15-25
- ISSN
- 0167-0115 (ISSN-L)
- PMC
- PMC2597723
- OpenAlex
- W2110310483
- Cited by
- 316
- References
- 182
- Citations by year
- 2026: 13 · 2025: 20 · 2024: 7 · 2023: 15 · 2022: 9 · 2021: 18 · 2020: 24 · 2019: 24 · 2018: 28 · 2017: 23 · 2016: 16 · 2015: 21 · 2014: 19 · 2013: 18 · 2012: 17
- FWCI
- 1.51
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Regulatory Peptides (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Diabetes and Digestive and Kidney Diseases (R01DK071082, R01DK047348)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Life Sciences › Neuroscience › Neurology › Vagus Nerve Stimulation Research
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Keywords
- vagus nerve, vagal afferents, vagal efferents, dietary intake, obesity, satiation, energy homeostasis, nutrient absorption, nutrient partitioning, bariatric surgery
- MeSH terms
- Animals, Eating, Humans, Models, Biological, Obesity, Vagus Nerve
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
