Gut hormone PYY3-36 physiologically inhibits food intake

The Mouse Brain in Stereotaxic Coordinates

Paxinos, G. (2001) · Cited by 12,859 · see citing works

Central nervous system control of food intake

Schwartz, M. W., Woods, S. C., Porte, D., Seeley, R. J., & Baskin, D. G. (2000) · Nature · doi:10.1038/35007534 · Cited by 6,451 · see citing works

mouse brain in stereotaxic coordinates

Franklin, K. B. J., & Paxinos, G. (1997) · Cited by 3,258 · see citing works

Leptin activates anorexigenic POMC neurons through a neural network in the arcuate nucleus

Cowley, M. A., Smart, J. L., Rubinstein, M., Cerdán, M. G., Diano, S., Horvath, T. L., Cone, R. D., & Low, M. J. (2001) · Nature · doi:10.1038/35078085 · Cited by 2,356 · see citing works

Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight

Kalra, S. P., Dube, M. G., Pu, S., Xu, B., Horváth, T. L., & Kalra, P. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.1.0357 · Cited by 1,556 · see citing works

Human distribution and release of a putative new gut hormone, peptide YY

Adrian, T. E., Ferri, G., Bacarese-Hamilton, A. J., Fuessl, H. S., Polak, J. M., & Bloom, S. R. (1985) · Gastroenterology · doi:10.1016/0016-5085(85)90211-2 · Cited by 1,064 · see citing works

Genetics of body-weight regulation

Barsh, G. S., Farooqi, I. S., & O’Rahilly, S. (2000) · Nature · doi:10.1038/35007519 · Cited by 775 · see citing works

c-Fos and Related Immediate Early Gene Products as Markers of Activity in Neuroendocrine Systems

Hoffman, G. E., Smith, M. S., & Verbalis, J. G. (1993) · Frontiers in Neuroendocrinology · doi:10.1006/frne.1993.1006 · Cited by 715 · see citing works

Exendin-4 reduces fasting and postprandial glucose and decreases energy intake in healthy volunteers

Edwards, C. M. B., Stanley, S. A., Davis, R. P., Brynes, A. E., Frost, G. S., Seal, L., Ghatei, M. A., & Bloom, S. R. (2001) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.2001.281.1.e155 · Cited by 464 · see citing works

Two molecular forms of Peptide YY (PYY) are abundant in human blood: characterization of a radioimmunoassay recognizing PYY 1–36 and PYY 3–36

Grandt, D., Schimiczek, M., Beglinger, C., Layer, P., Goebell, H., Eysselein, V. E., & Reeve, J. R. (1994) · Regulatory Peptides · doi:10.1016/0167-0115(94)90204-6 · Cited by 363 · see citing works

Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat

Butler, A. A., Marks, D. L., Fan, W., Kuhn, C. M., Bartolome, M. B., & Cone, R. D. (2001) · Nature Neuroscience · doi:10.1038/88423 · Cited by 332 · see citing works

Subtypes Y1 and Y2 of the Neuropeptide Y Receptor Are Respectively Expressed in Pro-Opiomelanocortin- and Neuropeptide-Y-Containing Neurons of the Rat Hypothalamic Arcuate Nucleus

Broberger, C., Landry, M., Wong, H., Walsh, J. N., & Hökfelt, T. G. M. (2008) · Neuroendocrinology · doi:10.1159/000127265 · Cited by 298 · see citing works

Cholecystokinin and satiety: current perspectives.

Moran, T. (2000) · Nutrition (Burbank, Los Angeles County, Calif.) · doi:10.1016/s0899-9007(00)00419-6 · Cited by 280 · see citing works

The central melanocortin system affects the hypothalamo-pituitary thyroid axis and may mediate the effect of leptin

Kim, M. S., Small, C. J., Stanley, S. A., Morgan, D. G. A., Seal, L. J., Kong, W. M., Edwards, C. M. B., Abusnana, S., Sunter, D., Ghatei, M. A., et al. (2000) · Journal of Clinical Investigation · doi:10.1172/jci8857 · Cited by 256 · see citing works

Hypothalamic localization of the feeding effect of agouti-related peptide and alpha-melanocyte-stimulating hormone.

Kim, M. S., Rossi, M., Abusnana, S., Sunter, D., Morgan, D. G., Small, C. J., Edwards, C. M., Heath, M., Stanley, S. A., Seal, L., et al. (2000) · Diabetes · doi:10.2337/diabetes.49.2.177 · Cited by 216 · see citing works

Activation of the ubiquitin pathway in rat skeletal muscle by catabolic doses of glucocorticoids

Auclair, D., Garrel, D. R., Zerouala, A. C., & Ferland, L. H. (1997) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1997.272.3.c1007 · Cited by 161 · see citing works

A model of gastric emptying using paracetamol absorption in intensive care patients

Tarling, M., Toner, C. C., Withington, P. S., BAXTER, M. K., Whelpton, R., & Goldhill, D. R. (1997) · Intensive Care Medicine · doi:10.1007/s001340050325 · Cited by 159 · see citing works

The reproducibility of subjective appetite scores

Raben, A., Tagliabue, A., & Astrup, A. V. (1995) · British Journal Of Nutrition · doi:10.1079/bjn19950056 · Cited by 141 · see citing works

Influence of meal composition on postprandial peripheral plasma concentrations of vasoactive peptides in man

Pedersen‐Bjergaard, U., Høt, U., Kelbæk, H., Schifter, S., Rehfeld, J. F., Faber, J. O., & Christensen, N. J. (1996) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.3109/00365519609088805 · Cited by 136 · see citing works

Primary structures of PYY, [Pro34]PYY, and PYY-(3–36) confer different conformations and receptor selectivity

Keire, D. A., Mannon, P., Kobayashi, M., Walsh, J. H., Solomon, T. E., & Reeve, J. R. (2000) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2000.279.1.g126 · Cited by 126 · see citing works

Zebrafish Genes for Neuropeptide Y and Peptide YY Reveal Origin by Chromosome Duplication from an Ancestral Gene Linked to the Homeobox Cluster

Söderberg, C., Kijas, A. W., Ringvall, M., Yan, Y., Postlethwait, J. H., Brodin, L., & Larhammar, D. (2000) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2000.0750908.x · Cited by 80 · see citing works

Peptide analogue studies of the hypothalamic neuropeptide Y receptor mediating pituitary adrenocorticotrophic hormone release

Small, C. J., Morgan, D. G. A., Meeran, K. M., Heath, M., Gunn, I., Edwards, C. M. B., Gardiner, J., Taylor, G. M., Hurley, J. D., Rossi, M., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.21.11686 · Cited by 67 · see citing works

A novel neuropeptide Y analog, N-acetyl [Leu28, Leu31]neuropeptide Y-(24–36), with functional specificity for the presynaptic (Y2) receptor

Potter, E. K., Barden, J. A., McCloskey, M. J. D., et al. (1994) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(94)90148-1 · Cited by 63 · see citing works

Leptin-induced decrease in food intake is not associated with changes in gastric emptying in lean mice

Barrachina, M. D., Martı́nez, V., Wei, J., & Taché, Y. (1997) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.1997.272.3.r1007 · Cited by 49 · see citing works

Neuropeptide Y Y5 receptor protein in the cortical/limbic system and brainstem of the rat: expression on γ-aminobutyric acid and corticotropin-releasing hormone neurons

Grove, K., Campbell, R. E., ffrench-Mullen, J. M. H., et al. (2000) · Neuroscience · doi:10.1016/s0306-4522(00)00308-0 · Cited by 47 · see citing works

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

den Besten, G., van Eunen, K., Groen, A. K., Venema, K., Reijngoud, D.-J., & Bakker, B. M. (2013) · Journal of Lipid Research · doi:10.1194/jlr.r036012 · Cited by 5,048 · see citing works

Gut microbiota in human metabolic health and disease

Fan, Y., & Pedersen, O. (2021) · Nature Reviews Microbiology · doi:10.1038/s41579-020-0433-9 · Cited by 4,724 · see citing works

Central nervous system control of food intake and body weight

Morton, G. J., Cummings, D. E., Baskin, D. G., Barsh, G. S., & Schwartz, M. W. (2006) · Nature · doi:10.1038/nature05026 · Cited by 2,503 · see citing works

Inhibition of Food Intake in Obese Subjects by Peptide YY _3–36

Batterham, R. L., Cohen, M. A., Ellis, S. M., Le Roux, C. W., Withers, D. J., Frost, G. S., Ghatei, M. A., & Bloom, S. R. (2003) · New England Journal of Medicine · doi:10.1056/nejmoa030204 · Cited by 1,604 · see citing works

Anatomy and regulation of the central melanocortin system

Cone, R. D. (2005) · Nature Neuroscience · doi:10.1038/nn1455 · Cited by 1,583 · see citing works

Long-term persistence of hormonal adaptations to weight loss

Sumithran, P., Prendergast, L. A., Delbridge, E., Purcell, K., Shulkes, A., Kriketos, A., & Proietto, J. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1105816 · Cited by 1,449 · see citing works

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults

Chambers, E. S., Viardot, A., Psichas, A., Morrison, D. J., Murphy, K. G., Zac-Varghese, S. E. K., MacDougall, K., Preston, T., Tedford, C., Finlayson, G. S., et al. (2015) · Gut · doi:10.1136/gutjnl-2014-307913 · Cited by 1,424 · see citing works

Gastrointestinal regulation of food intake

Cummings, D. E., & Overduin, J. (2007) · Journal of Clinical Investigation · doi:10.1172/jci30227 · Cited by 1,216 · see citing works

The Need to Feed

Saper, C. B., Chou, T. C., & Elmquist, J. K. (2002) · Neuron · doi:10.1016/s0896-6273(02)00969-8 · Cited by 1,120 · see citing works

Anti-obesity drug discovery: advances and challenges

Müller, T. D., Blüher, M., Tschöp, M. H., & DiMarchi, R. D. (2022) · Nature Reviews Drug Discovery · doi:10.1038/s41573-021-00337-8 · Cited by 1,021 · see citing works

Gut Hormone Profiles Following Bariatric Surgery Favor an Anorectic State, Facilitate Weight Loss, and Improve Metabolic Parameters

Roux, C. W. L., Aylwin, S. J. B., Batterham, R. L., Borg, C. M., Coyle, F., Prasad, V., Shurey, S., Ghatei, M. A., Patel, A. G., & Bloom, S. R. (2006) · Annals of Surgery · doi:10.1097/01.sla.0000183349.16877.84 · Cited by 985 · see citing works

Gender differences in insulin resistance, body composition, and energy balance

Geer, E. B., & Shen, W. (2009) · Gender Medicine · doi:10.1016/j.genm.2009.02.002 · Cited by 913 · see citing works

Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor

Xu, B., Goulding, E. H., Zang, K., Cepoi, D., Cone, R. D., Jones, K. R., Tecott, L. H., & Reichardt, L. F. (2003) · Nature Neuroscience · doi:10.1038/nn1073 · Cited by 896 · see citing works

Gut hormones and the regulation of energy homeostasis

Murphy, K. G., & Bloom, S. R. (2006) · Nature · doi:10.1038/nature05484 · Cited by 778 · see citing works

Neurobiology of food intake in health and disease

Morton, G. J., Meek, T. H., & Schwartz, M. W. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3745 · Cited by 748 · see citing works

Gut hormones as mediators of appetite and weight loss after Roux-en-Y gastric bypass

le Roux, C. W., Welbourn, R., Werling, M., Osborne, A., Kokkinos, A., Laurenius, A., Lönroth, H., Fändriks, L., Ghatei, M. A., Bloom, S. R., et al. (2007) · Annals of Surgery · doi:10.1097/sla.0b013e3180caa3e3 · Cited by 741 · see citing works

Dietary fibre modulates the gut microbiota

Cronin, P., Joyce, S. A., O’Toole, P. W., & O’Connor, E. M. (2021) · Nutrients · doi:10.3390/nu13051655 · Cited by 658 · see citing works

Studies on the Physiological Functions of the Melanocortin System

Cone, R. D. (2006) · Endocrine Reviews · doi:10.1210/er.2006-0034 · Cited by 615 · see citing works

Dietary fructose: implications for dysregulation of energy homeostasis and lipid/carbohydrate metabolism.

Havel, P. J. (2005) · Nutrition Reviews · doi:10.1111/j.1753-4887.2005.tb00132.x · Cited by 607 · see citing works

Microbial regulation of organismal energy homeostasis

Cani, P. D., Van Hul, M., Lefort, C., Depommier, C., Rastelli, M., & Everard, A. (2019) · Nature Metabolism · doi:10.1038/s42255-018-0017-4 · Cited by 569 · see citing works

The gut and energy balance: visceral allies in the obesity wars

Badman, M. K., & Flier, J. S. (2005) · Science · doi:10.1126/science.1109951 · Cited by 532 · see citing works

Gastric Bypass for Obesity: Mechanisms of Weight Loss and Diabetes Resolution

Cummings, D. E., Overduin, J., & Foster-Schubert, K. E. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-0433 · Cited by 503 · see citing works

Neuropeptide, Y, peptide YY and pancreatic polypeptide in the gut-brain axis

Holzer, P., Reichmann, F., & Farzi, A. (2012) · Neuropeptides · doi:10.1016/j.npep.2012.08.005 · Cited by 501 · see citing works

Feeding the microbiota–gut–brain axis: Diet, microbiome, and neuropsychiatry

Sandhu, K. V., Sherwin, E., Schellekens, H., Stanton, C., Dinan, T. G., & Cryan, J. F. (2017) · Translational Research · doi:10.1016/j.trsl.2016.10.002 · Cited by 491 · see citing works

Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells

Bohórquez, D. V., Shahid, R. A., Erdmann, A., Kreger, A. M., Wang, Y., Calakos, N., Wang, F., & Liddle, R. A. (2015) · Journal of Clinical Investigation · doi:10.1172/jci78361 · Cited by 484 · see citing works

Microbiota-derived metabolites as drivers of gut–brain communication

Ahmed, H., Leyrolle, Q., Koistinen, V., Kärkkäinen, O., Layé, S., Delzenne, N., & Hanhineva, K. (2022) · Gut Microbes · doi:10.1080/19490976.2022.2102878 · Cited by 462 · see citing works

Diet and the Microbiota–Gut–Brain Axis: Sowing the Seeds of Good Mental Health

Berding, K., Vlckova, K., Marx, W., Schellekens, H., Stanton, C., Clarke, G., Jacka, F., Dinan, T. G., & Cryan, J. F. (2021) · Advances in Nutrition · doi:10.1093/advances/nmaa181 · Cited by 451 · see citing works

Ileal brake: a sensible food target for appetite control. A review

Maljaars, P. W. J., Peters, H. P. F., Mela, D. J., & Masclee, A. A. M. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2008.07.018 · Cited by 451 · see citing works

Subcutaneous Oxyntomodulin Reduces Body Weight in Overweight and Obese Subjects

Wynne, K., Park, A. J., Small, C. J., Patterson, M., Ellis, S. M., Murphy, K. G., Wren, A. M., Frost, G. S., Meeran, K., Ghatei, M. A., et al. (2005) · Diabetes · doi:10.2337/diabetes.54.8.2390 · Cited by 435 · see citing works

The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats

Koda, S., Date, Y., Murakami, N., Shimbara, T., Hanada, T., Toshinai, K., Niijima, A., Furuya, M., Inomata, N., Osuye, K., et al. (2005) · Endocrinology · doi:10.1210/en.2004-1266 · Cited by 431 · see citing works

Effects of Roux-en-Y Gastric Bypass Surgery on Fasting and Postprandial Concentrations of Plasma Ghrelin, Peptide YY, and Insulin

Korner, J., Bessler, M., Cirilo, L. J., Conwell, I. M., Daud, A., Restuccia, N. L., & Wardlaw, S. L. (2005) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2004-1076 · Cited by 417 · see citing works

Role of the gut microbiota in host appetite control: bacterial growth to animal feeding behaviour

Fetissov, S. O. (2017) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2016.150 · Cited by 403 · see citing works

Glucagon-like peptide-1, peptide YY, hunger, and satiety after gastric bypass surgery in morbidly obese subjects

Morínigo, R., Moizé, V., Musri, M., Lacy, A. M., Navarro, S., Marín, J. L., Delgado, S., Casamitjana, R., & Vidal, J. (2006) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2005-0904 · Cited by 397 · see citing works

Gut microbiota-mediated inflammation in obesity: a link with gastrointestinal cancer

Cani, P. D., & Jordan, B. F. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0025-6 · Cited by 383 · see citing works

Enteroendocrine cells: a review of their role in brain–gut communication

Latorre, R., Sternini, C., De Giorgio, R., & Greenwood‐Van Meerveld, B. (2016) · Neurogastroenterology & Motility · doi:10.1111/nmo.12754 · Cited by 392 · see citing works

Gut Hormones and Appetite Control: A Focus on PYY and GLP-1 as Therapeutic Targets in Obesity

Silva, A. D., & Bloom, S. R. (2012) · Gut and Liver · doi:10.5009/gnl.2012.6.1.10 · Cited by 373 · see citing works

Hormonal regulation of food intake

Stanley, S., Wynne, K., McGowan, B., & Bloom, S. (2005) · Physiological Reviews · doi:10.1152/physrev.00015.2004 · Cited by 372 · see citing works

Peptide YY3–36 and Glucagon-Like Peptide-17–36 Inhibit Food Intake Additively

Neary, N. M., Small, C. J., Druce, M. R., Park, A. J., Ellis, S. M., Semjonous, N. M., Dakin, C. L., Filipsson, K., Wang, F., Kent, A. S., et al. (2005) · Endocrinology · doi:10.1210/en.2005-0237 · Cited by 371 · see citing works

The role of peptide YY in appetite regulation and obesity

Karra, E., Chandarana, K., & Batterham, R. L. (2009) · The Journal of Physiology · doi:10.1113/jphysiol.2008.164269 · Cited by 336 · see citing works

Central and Peripheral Regulation of Food Intake and Physical Activity: Pathways and Genes

Lenard, N. R., & Berthoud, H. (2008) · Obesity · doi:10.1038/oby.2008.511 · Cited by 338 · see citing works

How Palatable Food Disrupts Appetite Regulation

Erlanson‐Albertsson, C. (2005) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/j.1742-7843.2005.pto_179.x · Cited by 330 · see citing works

Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth

Breton, J., Tennoune, N., Lucas, N., Francois, M., Legrand, R., Jacquemot, J., Goichon, A., Guérin, C., Peltier, J., Pestel-Caron, M., et al. (2016) · Cell Metabolism · doi:10.1016/j.cmet.2015.10.017 · Cited by 321 · see citing works

The complex interaction between obesity, metabolic syndrome and reproductive axis: A narrative review

Michalakis, K., Mintziori, G., Kaprara, A., Tarlatzis, B. C., & Goulis, D. G. (2013) · Metabolism · doi:10.1016/j.metabol.2012.08.012 · Cited by 321 · see citing works

The vagus nerve, food intake and obesity

Berthoud, H.-R. (2008) · Regulatory Peptides · doi:10.1016/j.regpep.2007.08.024 · Cited by 316 · see citing works

The defence of body weight: a physiological basis for weight regain after weight loss

Sumithran, P., & Proietto, J. (2013) · Clinical Science · doi:10.1042/cs20120223 · Cited by 310 · see citing works

Vagal and hormonal gut-brain communication: from satiation to satisfaction

Berthoud, H. ‐. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01104.x · Cited by 307 · see citing works

Regulation of energy homeostasis by the NPY system

Loh, K., Herzog, H., & Shi, Y.-C. (2015) · Trends in Endocrinology & Metabolism · doi:10.1016/j.tem.2015.01.003 · Cited by 293 · see citing works

Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve

Luyer, M. D., Greve, J. W. M., Hadfoune, M., Jacobs, J. A., Dejong, C. H., & Buurman, W. A. (2005) · The Journal of Experimental Medicine · doi:10.1084/jem.20042397 · Cited by 295 · see citing works

Gut hormones, early dumping and resting energy expenditure in patients with good and poor weight loss response after Roux-en-Y gastric bypass

Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Kielgast, U., Jacobsen, S. H., Clausen, T. R., Worm, D., Hartmann, B., Rehfeld, J. F., Damgaard, M., et al. (2013) · International Journal of Obesity · doi:10.1038/ijo.2013.15 · Cited by 276 · see citing works

Acute effects of intravenous and rectal acetate on glucagon-like peptide-1, peptide YY, ghrelin, adiponectin and tumour necrosis factor-α

Freeland, K. R., & Wolever, T. M. S. (2010) · British Journal of Nutrition · doi:10.1017/s0007114509991863 · Cited by 275 · see citing works

Role of the gut-brain axis in energy and glucose metabolism

Wachsmuth, H. R., Weninger, S. N., & Duca, F. A. (2022) · Experimental & Molecular Medicine · doi:10.1038/s12276-021-00677-w · Cited by 269 · see citing works

Arcuate NPY Controls Sympathetic Output and BAT Function via a Relay of Tyrosine Hydroxylase Neurons in the PVN

Shi, Y.-C., Lau, J., Lin, Z., Zhang, H., Zhai, L., Sperk, G., Heilbronn, R., Mietzsch, M., Weger, S., Huang, X.-F., et al. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.01.006 · Cited by 266 · see citing works

Kisspeptin Directly Excites Anorexigenic Proopiomelanocortin Neurons but Inhibits Orexigenic Neuropeptide Y Cells by an Indirect Synaptic Mechanism

Fu, L.-Y., & van den Pol, A. N. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.2098-10.2010 · Cited by 243 · see citing works

Differential Effects of Gastric Bypass and Banding on Circulating Gut Hormone and Leptin Levels

Korner, J., Inabnet, W., Conwell, I. M., Taveras, C., Daud, A., Olivero‐Rivera, L., Restuccia, N. L., & Bessler, M. (2006) · Obesity · doi:10.1038/oby.2006.179 · Cited by 240 · see citing works

Current and investigational antiobesity agents and obesity therapeutic treatment targets

Bays, H. E. (2004) · Obesity Research · doi:10.1038/oby.2004.151 · Cited by 228 · see citing works

Neuropeptide Y Family Receptors Traffic via the Bardet-Biedl Syndrome Pathway to Signal in Neuronal Primary Cilia

Loktev, A. V., & Jackson, P. K. (2013) · Cell Reports · doi:10.1016/j.celrep.2013.11.011 · Cited by 212 · see citing works

Effect of pramlintide on satiety and food intake in obese subjects and subjects with type 2 diabetes

Chapman, I., Parker, B., Doran, S., Feinle-Bisset, C., Wishart, J., Strobel, S., Wang, Y., Burns, C., Lush, C., Weyer, C., et al. (2005) · Diabetologia · doi:10.1007/s00125-005-1732-4 · Cited by 205 · see citing works

Neurotrophic factor control of satiety and body weight

Xu, B., & Xie, X. (2016) · Nature reviews. Neuroscience · doi:10.1038/nrn.2016.24 · Cited by 203 · see citing works

Taste receptor signaling in the mammalian gut

Rozengurt, E., & Sternini, C. (2007) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2007.10.002 · Cited by 203 · see citing works

The L-cell in nutritional sensing and the regulation of appetite

Spreckley, E. (2015) · Frontiers in Nutrition · doi:10.3389/fnut.2015.00023 · Cited by 198 · see citing works

Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Wewer Albrechtsen, N. J., Rehfeld, J. F., Hartmann, B., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.121 · Cited by 185 · see citing works

Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes

Horowitz, M., Flint, A., Jones, K. L., Hindsberger, C., Rasmussen, M. F., Kapitza, C., Doran, S., Jax, T., Zdravkovic, M., & Chapman, I. M. (2012) · Diabetes Research and Clinical Practice · doi:10.1016/j.diabres.2012.02.016 · Cited by 179 · see citing works

Effects of Weight Loss and Long-Term Weight Maintenance With Diets Varying in Protein and Glycemic Index on Cardiovascular Risk Factors: The Diet, Obesity, and Genes (DiOGenes) Study: A Randomized, Controlled Trial

Gögebakan, Ö., Kohl, A., Osterhoff, M. A., van Baak, M. A., Jebb, S. A., Papadaki, A., Martinez, J. A., Handjieva-Darlenska, T., Hlavaty, P., Weickert, M. O., et al. (2011) · Circulation · doi:10.1161/circulationaha.111.033274 · Cited by 180 · see citing works

Comparable effects of moderate intensity exercise on changes in anorectic gut hormone levels and energy intake to high intensity exercise

Ueda, S.-Y., Yoshikawa, T., Katsura, Y., Usui, T., & Fujimoto, S. (2009) · Journal of Endocrinology · doi:10.1677/joe-09-0190 · Cited by 178 · see citing works

Inter‐organ communication: a gatekeeper for metabolic health

Castillo‐Armengol, J., Fajas, L., & Lopez‐Mejia, I. C. (2019) · The EMBO Reports · doi:10.15252/embr.201947903 · Cited by 178 · see citing works

Gut hypertrophy after gastric bypass is associated with increased glucagon-like peptide 2 and intestinal crypt cell proliferation

le Roux, C. W., Borg, C., Wallis, K., Vincent, R. P., Bueter, M., Goodlad, R., Ghatei, M. A., Patel, A., Bloom, S. R., & Aylwin, S. J. B. (2010) · Annals of Surgery · doi:10.1097/sla.0b013e3181d3d21f · Cited by 176 · see citing works

Efficacy and safety of intranasal peptide YY3-36 for weight reduction in obese adults

Gantz, I., Erondu, N., Mallick, M., Musser, B., Krishna, R., Tanaka, W. K., Snyder, K., Stevens, C., Stroh, M. A., Zhu, H., et al. (2007) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2006-1806 · Cited by 163 · see citing works

Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota

Mishra, A. K., Dubey, V., & Ghosh, A. R. (2016) · Metabolism · doi:10.1016/j.metabol.2015.10.008 · Cited by 161 · see citing works

Gene-Environment Interactions Controlling Energy and Glucose Homeostasis and the Developmental Origins of Obesity

Bouret, S., Levin, B. E., & Ozanne, S. E. (2015) · Physiological Reviews · doi:10.1152/physrev.00007.2014 · Cited by 157 · see citing works

Gut hormones in microbiota-gut-brain cross-talk

Sun, L.-J., Li, J.-N., & Nie, Y.-Z. (2020) · Chinese Medical Journal · doi:10.1097/cm9.0000000000000706 · Cited by 145 · see citing works

The intestine as an endocrine organ and the role of gut hormones in metabolic regulation

Bany Bakar, R., Reimann, F., & Gribble, F. M. (2023) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-023-00830-y · Cited by 144 · see citing works

Signals that influence food intake and body weight

WOODS, S. (2005) · Physiology & Behavior · doi:10.1016/j.physbeh.2005.08.060 · Cited by 131 · see citing works

Bariatric surgery, bone loss, obesity and possible mechanisms

Brzozowska, M. M., Sainsbury, A., Eisman, J. A., Baldock, P. A., & Center, J. R. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01050.x · Cited by 128 · see citing works

New targets to treat obesity and the metabolic syndrome

Martin, K. A., Mani, M. V., & Mani, A. (2015) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2015.03.093 · Cited by 121 · see citing works

The role of gut hormone peptide YY in energy and glucose homeostasis: Twelve years on

Manning, S., & Batterham, R. L. (2014) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021113-170404 · Cited by 124 · see citing works

Short-chain fatty acids, secondary bile acids and indoles: gut microbial metabolites with effects on enteroendocrine cell function and their potential as therapies for metabolic disease

Masse, K. E., & Lu, V. B. (2023) · Frontiers in Endocrinology · doi:10.3389/fendo.2023.1169624 · Cited by 120 · see citing works

The neuropharmacology of relapse to food seeking: Methodology, main findings, and comparison with relapse to drug seeking

Nair, S. G., Adams-Deutsch, T., Epstein, D. H., & Shaham, Y. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.05.003 · Cited by 112 · see citing works

Recent developments in the pathophysiology of irritable bowel syndrome

El-Salhy, M. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i25.7621 · Cited by 111 · see citing works

Mechanisms responsible for excess weight loss after bariatric surgery

Ionut, V., & Bergman, R. N. (2011) · Journal of Diabetes Science and Technology · doi:10.1177/193229681100500536 · Cited by 105 · see citing works

The role of PYY in feeding regulation

Ueno, H., Yamaguchi, H., Mizuta, M., & Nakazato, M. (2008) · Regulatory Peptides · doi:10.1016/j.regpep.2007.09.011 · Cited by 105 · see citing works

Effect of subcutaneous injections of PYY_1-36 and PYY_3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males

Sloth, B., Davidsen, L., Holst, J. J., Flint, A., & Astrup, A. (2007) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00153.2007 · Cited by 104 · see citing works

Changes in gut hormones after bariatric surgery

Vincent, R. P., & Le Roux, C. W. (2008) · Clinical Endocrinology · doi:10.1111/j.1365-2265.2007.03164.x · Cited by 100 · see citing works

Going with the grain: Fiber, cognition, and the microbiota-gut-brain-axis

Berding, K., Carbia, C., & Cryan, J. F. (2021) · Experimental Biology and Medicine · doi:10.1177/1535370221995785 · Cited by 100 · see citing works

Central and Peripheral Administration of Secretin Inhibits Food Intake in Mice through the Activation of the Melanocortin System

Cheng, C. Y. Y., Chu, J. Y. S., & Chow, B. K. C. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2010.178 · Cited by 98 · see citing works

Sex-dependent control of murine emotional-affective behaviour in health and colitis by peptide YY and neuropeptide Y

Painsipp, E., Herzog, H., Sperk, G., & Holzer, P. (2011) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.2011.01326.x · Cited by 93 · see citing works

Recent advances in clinical practice challenges and opportunities in the management of obesity

Acosta, A., Abu Dayyeh, B. K., Port, J. D., & Camilleri, M. (2014) · Gut · doi:10.1136/gutjnl-2013-306235 · Cited by 91 · see citing works

Gut adaptation after metabolic surgery and its influences on the brain, liver and cancer

Sinclair, P., Brennan, D. J., & le Roux, C. W. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0057-y · Cited by 91 · see citing works

Normalizing eating behavior reduces body weight and improves gastrointestinal hormonal secretion in obese adolescents

Galhardo, J., Hunt, L. P., Lightman, S. L., Sabin, M. A., Bergh, C., Sodersten, P., & Shield, J. P. H. (2012) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2011-1999 · Cited by 89 · see citing works

The Effect of a Subcutaneous Infusion of GLP-1, OXM, and PYY on Energy Intake and Expenditure in Obese Volunteers

Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Albrechtsen, N. J. W., Holst, J. J., & Bloom, S. R. (2017) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2017-00469 · Cited by 88 · see citing works

The Regulation of Peripheral Metabolism by Gut-Derived Hormones

Sun, E. W. L., Martin, A. M., Young, R. L., & Keating, D. J. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2018.00754 · Cited by 71 · see citing works

The role of peptide YY in regulating glucose homeostasis

Boey, D., Sainsbury, A., & Herzog, H. (2007) · Peptides · doi:10.1016/j.peptides.2006.07.031 · Cited by 77 · see citing works

The incretin/glucagon system as a target for pharmacotherapy of obesity

Del Prato, S., Gallwitz, B., Holst, J. J., & Meier, J. J. (2022) · Obesity Reviews · doi:10.1111/obr.13372 · Cited by 77 · see citing works

Gut-derived signaling molecules and vagal afferents in the control of glucose and energy homeostasis

Thorens, B., & Larsen, P. J. (2004) · Current Opinion in Clinical Nutrition and Metabolic Care · doi:10.1097/01.mco.0000134368.91900.84 · Cited by 73 · see citing works

Peptide hormones regulating appetite—focus on neuroimaging studies in humans

Schloegl, H., Percik, R., Horstmann, A., Villringer, A., & Stumvoll, M. (2011) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.1154 · Cited by 70 · see citing works

Influence of a regular, standardized meal on clinical chemistry analytes

Lima-Oliveira, G., Salvagno, G. L., Lippi, G., Gelati, M., Montagnana, M., Danese, E., Picheth, G., & Guidi, G. C. (2012) · Annals of Laboratory Medicine · doi:10.3343/alm.2012.32.4.250 · Cited by 63 · see citing works

The new era of drug therapy for obesity: the evidence and the expectations

Jones, B. J., & Bloom, S. R. (2015) · Drugs · doi:10.1007/s40265-015-0410-1 · Cited by 58 · see citing works

Obesity medications in development

Rebello, C. J., & Greenway, F. L. (2020) · Expert Opinion on Investigational Drugs · doi:10.1080/13543784.2020.1705277 · Cited by 62 · see citing works

Impact of Nutrient Type and Sequence on Glucose Tolerance: Physiological Insights and Therapeutic Implications

Nesti, L., Mengozzi, A., & Tricò, D. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00144 · Cited by 53 · see citing works

Energy Homeostasis and Gastrointestinal Endocrine Differentiation Do Not Require the Anorectic Hormone Peptide YY

Schonhoff, S., Baggio, L., Ratineau, C., Ray, S. K., Lindner, J., Magnuson, M. A., Drucker, D. J., & Leiter, A. B. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.10.4189-4199.2005 · Cited by 53 · see citing works

Neuropeptide Y: History and Overview

Tatemoto, K. (2004) · Handbook of Experimental Pharmacology · doi:10.1007/978-3-642-18764-3_1 · Cited by 52 · see citing works

In vivo interaction of neuropeptide Y and peptide YY with σ receptor sites in the mouse brain

Roman, F. J., Martin, B., & Junien, J. (1993) · European Journal of Pharmacology · doi:10.1016/0014-2999(93)90255-g · Cited by 10 · see citing works

Neuropeptide Y (NPY)-induced feeding behavior in female rats: comparison with human NPY ([Met17]NPY), NPY analog ([norLeu4]NPY) and peptide YY

Clark, J. T., Sahu, A., Kalra, P. S., Balasubramaniam, A., & Kalra, S. P. (1987) · Regulatory Peptides · doi:10.1016/0167-0115(87)90030-9 · Cited by 96 · see citing works

Effects of various neuropeptide Y/peptide YY fragments on electrically‐evoked contractions of the rat vas deferens

Grundemar, L., & Håkanson, R. (1990) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1990.tb12075.x · Cited by 61 · see citing works

Neuropeptide Y, peptide YY and C‐terminal fragments release histamine from rat peritoneal mast cells

Grundemar, L., & Håkanson, R. (1991) · British Journal of Pharmacology · doi:10.1111/j.1476-5381.1991.tb12505.x · Cited by 55 · see citing works

Robust feeding following central administration of neuropeptide Y or peptide YY in chicks, Gallus domesticus

Kuenzel, W. J., Douglass, L. W., & Davison, B. A. (1987) · Peptides · doi:10.1016/0196-9781(87)90066-0 · Cited by 217 · see citing works