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Cited by 490

The DOI matches its Crossref record; 144 of the 144 references it cites were found in a registry or an index.

A review of the carcinogenic potential of bisphenol A

Open access
Seachrist, Darcie D., Bonk, Kristen W., Ho, Shuk-Mei, Prins, Gail S., Soto, Ana M., Keri, Ruth A.·2016·Reproductive Toxicology

Abstract

The estrogenic properties of bisphenol A (BPA), a ubiquitous synthetic monomer that can leach into the food and water supply, have prompted considerable research into exposure-associated health risks in humans. Endocrine-disrupting properties of BPA suggest it may impact developmental plasticity during early life, predisposing individuals to disease at doses below the oral reference dose (RfD) established by the Environmental Protection Agency in 1982. Herein, we review the current in vivo literature evaluating the carcinogenic properties of BPA. We conclude that there is substantial evidence from rodent studies indicating that early-life BPA exposures below the RfD lead to increased susceptibility to mammary and prostate cancer. Based on the definitions of “carcinogen” put forth by the International Agency for Research on Cancer and the National Toxicology Program, we propose that BPA may be reasonably anticipated to be a human carcinogen in the breast and prostate due to its tumor promoting properties.

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Crossref · 10.1016/j.reprotox.2015.09.006

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Metadata

Authors
Seachrist, D. D., Bonk, K. W., Ho, S.-M., Prins, G. S., Soto, A. M., & Keri, R. A.
Venue
Reproductive Toxicology
Publisher
Elsevier BV
Published
2016-01
Volume
59
Pages
167-182
ISSN
0890-6238 (ISSN-L)
OpenAlex
W2145415601
Cited by
490
References
144
FWCI
19.35
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: A review of the carcinogenic potential of bisphenol A. https://app.cochat.ai/papers/10.1016/j.reprotox.2015.09.006
The paper
Seachrist, D. D., Bonk, K. W., Ho, S.-M., Prins, G. S., Soto, A. M., & Keri, R. A. (2016). A review of the carcinogenic potential of bisphenol A. Reproductive Toxicology. https://doi.org/10.1016/j.reprotox.2015.09.006

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.