Cited by 398Cardiovascular and exercise physiologySports Performance and TrainingNeuroscience of respiration and sleep

The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.

Consequences of exercise-induced respiratory muscle work

Dempsey, Jerome A., Romer, Lee, Rodman, Joshua, Miller, Jordan, Smith, Curtis·2006·Respiratory Physiology & Neurobiology

DOI 10.1016/j.resp.2005.12.015

Open this paper in CoChat — free account

Abstract

We briefly review the evidence for a hypothesis, which links the ventilatory response to heavy intensity, sustained exercise-to-exercise performance limitation in health. A key step in this linkage is a respiratory muscle fatigue-induced metaboreflex, which increases sympathetic vasoconstrictor outflow, causing reduced blood flow to locomotor muscles and locomotor muscle fatigue. In turn, the limb fatigue comprises an important dual contribution to both peripheral and central fatigue mechanisms, which contribute to limiting exercise performance. Clinical implications for respiratory limitations to exercise in patients with chronic obstructive lung disease (COPD) and chronic heart failure (CHF) are discussed and key unresolved problems are outlined.

Integrity signals

Registry

Crossref · 10.1016/j.resp.2005.12.015

Cites

35 of 35 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Spinal and Supraspinal Factors in Human Muscle Fatigue
Gandevia, S. C. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.4.1725 · Cited by 3,855
Dynamic Hyperinflation and Exercise Intolerance in Chronic Obstructive Pulmonary Disease
O'DONNELL, D. E., REVILL, S. M., & WEBB, K. A. (2001) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.164.5.2012122 · Cited by 1,076
Respiratory muscle work compromises leg blood flow during maximal exercise
Harms, C. A., Babcock, M. A., McClaran, S. R., Pegelow, D. F., Nickele, G. A., Nelson, W. B., & Dempsey, J. A. (1997) · Journal of Applied Physiology · doi:10.1152/jappl.1997.82.5.1573 · Cited by 711
Self-citation
Exercise‐induced diaphragmatic fatigue in healthy humans.
Johnson, B. D., Babcock, M. A., Suman-Vejas, O. E., & Dempsey, J. A. (1993) · The Journal of Physiology · doi:10.1113/jphysiol.1993.sp019477 · Cited by 487
Self-citation
Proportional Assist Ventilation, a New Approach to Ventilatory Support: Theory
Younes, M. K. (1992) · American Review of Respiratory Disease · doi:10.1164/ajrccm/145.1.114 · Cited by 483
Effects of respiratory muscle work on cardiac output and its distribution during maximal exercise
Harms, C. A., Wetter, T. J., McClaran, S. R., Pegelow, D. F., Nickele, G. A., Nelson, W. B., Hanson, P., & Dempsey, J. A. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.85.2.609 · Cited by 469
Self-citation
Effects of respiratory muscle work on exercise performance
Harms, C. A., Wetter, T. J., St. Croix, C. M., Pegelow, D. F., & Dempsey, J. A. (2000) · Journal of Applied Physiology · doi:10.1152/jappl.2000.89.1.131 · Cited by 419
Self-citation
Mechanical constraints on exercise hyperpnea in endurance athletes
Johnson, B. D., Saupe, K. W., & Dempsey, J. A. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.73.3.874 · Cited by 382
Self-citation
Oxygen cost of exercise hyperpnea: implications for performance
Aaron, E. A., Seow, K. C., Johnson, B. D., & Dempsey, J. A. (1992) · Journal of Applied Physiology · doi:10.1152/jappl.1992.72.5.1818 · Cited by 377
Self-citation
Fatiguing inspiratory muscle work causes reflex reduction in resting leg blood flow in humans
Sheel, A. W., Derchak, P. A., Morgan, B. J., Pegelow, D. F., Jacques, A. J., & Dempsey, J. A. (2001) · The Journal of Physiology · doi:10.1111/j.1469-7793.2001.0277k.x · Cited by 331
Self-citation

Flagged first, then by citations

Show all 35 references

Research works printed but not linked: 1

Miller, 2005, Respiratory muscle metaboreflex limits locomotor limb blood flow during submaximal exercise in CHF, FASEB J., 19

Sorted by citations

Items 201–300 of 397

Relationship between Respiratory Muscle Strength and Exercise Tolerance
Sugiura, H., Ohta, K., Minatani, S., Tanoue, H., Kokubo, A., Kanada, Y., & Sako, S. (2009) · Journal of Physical Therapy Science · doi:10.1589/jpts.21.393 · Cited by 8
The misuse of respiratory resistive loading during aerobic exercises: revisiting mechanisms of “standalone” inspiratory muscle training
Rodrigues, G. D., & MCCONNELL, A. K. (2024) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.00396.2023 · Cited by 8
Inspiratory muscle warm up improves 400 m performance in elite male runners
Yılmaz, Y. A., Tosun, M. İ., Demirkan, E., Can, S., Özkan, A., Arıcı, M., Kutlu, M., Ayrancı, M., Marković, M., Arıcı, İ. E., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-14797-0 · Cited by 9
The Effect of Inspiratory Muscle Warm-Up on VO2 Kinetics during Submaximal Rowing
Arend, M., Kivastik, J., Talts, J., & Mäestu, J. (2021) · Sports · doi:10.3390/sports9030042 · Cited by 7
Inspiratory Muscle Training Improves Maximal Inspiratory Pressure Without Increasing Performance in Elite Swimmers
Gómez-Albareda, E., Viscor, G., & García, I. (2023) · International Journal of Sports Physiology and Performance · doi:10.1123/ijspp.2022-0238 · Cited by 7
Improving Endurance Exercise Performance at High Altitude: Traditional and Nontraditional Approaches
Salgado, R. M., Ryan, B. J., Seeley, A. D., & Charkoudian, N. (2024) · Exercise and Sport Sciences Reviews · doi:10.1249/jes.0000000000000347 · Cited by 9
Association of Oscillatory Ventilation during Cardiopulmonary Test to Clinical and Functional Variables of Chronic Heart Failure Patients
Reis, H. V., Sperandio, P. A., Corrêa, C. L., Guizilini, S., Neder, J. A., Borghi‐Silva, A., & Reis, M. S. (2018) · Brazilian Journal of Cardiovascular Surgery · doi:10.21470/1678-9741-2017-0158 · Cited by 7
Breathing valve resistance alters physiological responses during a graded exercise test
Kim, S., Homestead, E. P., & Byrnes, W. C. (2018) · European Journal of Applied Physiology · doi:10.1007/s00421-018-3922-z · Cited by 7
Inspiratory muscle training in young, race-fit Thoroughbred racehorses during a period of detraining
Katz, L. M., Stallard, J., Holtby, A. R., Hill, E. W., Allen, K., & Sweeney, J. S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0225559 · Cited by 7
A flow resistive inspiratory muscle training mask worn during high-intensity interval training does not improve 5 km running time-trial performance
Faghy, M. A., Brown, P. I., Davis, N. M., Mayes, J., & Maden‐Wilkinson, T. (2020) · European Journal of Applied Physiology · doi:10.1007/s00421-020-04505-3 · Cited by 7
Psychophysiological Responses During a Cycling Test to Exhaustion While Wearing the Elevation Training Mask
López-Pérez, M. E., Romero‐Arenas, S., Colomer‐Poveda, D., Keller, M. B., & Márquez, G. (2020) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000003626 · Cited by 7
Application of respiratory muscle training for improved intermittent exercise performance in team sports: a narrative review
Kowalski, T., Rodrigues, G. D., & Zanini, M. (2025) · Frontiers in Sports and Active Living · doi:10.3389/fspor.2025.1632207 · Cited by 6
Maximal pulmonary ventilation and lactate affect the anaerobic performance in young women exposed to hypobaric hypoxia
Paéz, V., Rodriguez-Fernández, M., Silva‐Urra, J., Núñez-Espinosa, C. A., & Lang, M. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1110477 · Cited by 6
Respiratory and locomotor muscle blood flow measurements using near-infrared spectroscopy and indocyanine green dye in health and disease
Megaritis, D., Echevarria, C., & Vogiatzis, I. (2024) · Chronic Respiratory Disease · doi:10.1177/14799731241246802 · Cited by 6
Inspiratory muscle weakness further impairs exercise capacity and respiratory functions and increases dyspnea perception in patients with heart failure
Katayıfçı, N., & Güçlü, M. B. (2025) · Scientific Reports · doi:10.1038/s41598-025-16492-6 · Cited by 6
Effects of Respiratory Muscle Warm-up on High-Intensity Exercise Performance
Thurston, T. S., Coburn, J. W., Brown, L. E., Bartolini, A., Beaudette, T. L., Karg, P., McLeland, K. A., Arevalo, J. A., Judelson, D. A., & Galpin, A. J. (2015) · Sports · doi:10.3390/sports3040312 · Cited by 6
Electrical activity of the diaphragm during progressive cycling exercise in endurance-trained men
Poulsen, M. K., Thomsen, L. P., Mifsud, N. L., Nygaard, N.-P. B., Jørgensen, R. M., Kjærgaard, S., & Karbing, D. S. (2014) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2014.10.012 · Cited by 6
Quadriceps Endurance Increases Following Cycling Exercise With Non-Invasive Ventilation In Moderate-To-Severe COPD Patients. A Non-Randomized Controlled Study
Labeix, P., Berger, M., Court‐Fortune, I., Féasson, L., Vergès, S., & Costes, F. (2019) · International Journal of COPD · doi:10.2147/copd.s216347 · Cited by 6
The Prevalence of Expiratory Flow Limitation in Youth Elite Male Cyclists
COX, K. R., Smith, J. R., Luden, N. D., Saunders, M. J., & Kurti, S. P. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002325 · Cited by 6
Clinical importance of respiratory muscle fatigue in patients with cardiovascular disease
Taya, M., Amiya, E., Hatano, M., Saito, A., Nitta, D., Maki, H., Hosoya, Y., Minatsuki, S., Tsuji, M., Sato, T., et al. (2020) · Medicine · doi:10.1097/md.0000000000021794 · Cited by 6
Nox4 Knockout Does Not Prevent Diaphragm Atrophy, Contractile Dysfunction, or Mitochondrial Maladaptation in the Early Phase Post-Myocardial Infarction in Mice
Hahn, D., Kumar, R. A., Muscato, D. R., RYAN, T. E., SchrÃ¶der, K., & Ferreira, L. F. (2021) · Cellular Physiology and Biochemistry · doi:10.33594/000000400 · Cited by 6
Patterns of Changes in Respiratory Muscle Strength over 1 Year in Non-Sarcopenia, Sarcopenia, and Severe Sarcopenia
Sawaya, Y., Hirose, T., Ishizaka, M., Shiba, T., Sato, R., Akira, K. U. B. O., & Urano, T. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph192416571 · Cited by 6
Effect of inspiratory muscle training with load compared with sham training on blood pressure in individuals with hypertension: study protocol of a double-blind randomized clinical trial
Posser, S. R., Callegaro, C. C., Moreira, M. B., & Moreira, L. B. (2016) · Trials · doi:10.1186/s13063-016-1514-y · Cited by 6
Correlation Between Muscle Strength, Pulmonary Function and Respiratory Muscle in Children with Cerebral Palsy
Shin, S.-O., & Kim, N.-S. (2016) · Journal of the Korean Society of Physical Medicine · doi:10.13066/kspm.2016.11.2.123 · Cited by 6
The effect of breathing pattern retraining on performance in competitive cyclists
Vickery, R. L. (2008) · Tuwhera (Auckland University of Technology) · Cited by 6
Inspiratory muscle training in natural bodybuilders: adaptations in diaphragm muscle thickness and maximal strength
Güler, I., Yılmaz, C., Soylu, H. H., BİRİNCİ, M. C., Arslan, A., Ocak, H., ÇAYIR, H., Kavuran, K., SAÇ, A., Uçar, M. A., et al. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1628146 · Cited by 6
Maximal inspiratory pressure is associated with health-related quality of life and is a reliable method for evaluation of patients on hemodialysis
Vieira, C. F. D., Costa, H. S., Lima, M. M. O., Alves, F. L., Rodrigues, V. G. B., Maciel, E. H. B., Prates, M. C. S. M., Lima, V. P., Mendonça, V. A., Lacerda, A. C. R., et al. (2020) · Physiotherapy Theory and Practice · doi:10.1080/09593985.2020.1818338 · Cited by 5
Relationship between respiratory sarcopenia and respiratory muscle weakness in community-dwelling older adults: a preliminary cross-sectional study
Inomoto, A., Kanzaki, R., Suzuki, Y., Hiroshige, K., Yotsumoto, T., Yoshida, Y., Nakatou, K., Tokitoh, M., Kawakami, J., Nagano, T., et al. (2024) · Journal of Physical Therapy Science · doi:10.1589/jpts.36.603 · Cited by 5
The association between normal lung function and peak oxygen uptake in patients with exercise intolerance and coronary artery disease
Rasch-Halvorsen, Ø., Hassel, E., Brumpton, B. M., Jenssen, H., Spruit, M. A., Langhammer, A., & Steinshamn, S. (2020) · PLoS ONE · doi:10.1371/journal.pone.0232693 · Cited by 5
Comparison of Effect of High-Intensity Interval Training and Aerobic Training on Respiratory Volumes in Female Students.
Shadmehri, S., Kazemi, N., & Heydari, F. Z. (2021) · PubMed Central · Cited by 5
Insights into the Serum Metabolic Adaptations in Response to Inspiratory Muscle Training: A Metabolomic Approach Based on 1H NMR and UHPLC-HRMS/MS
Castro, A., Catai, A. M., Rehder‐Santos, P., Signini, É. D. F., de Abreu, R. M., Silva, C. D. D., Dato, C. C., Oliveira, R. V., & Ferreira, A. G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms242316764 · Cited by 5
Exploratory study of factors associated with probable respiratory sarcopenia in elderly subjects
Umehara, T., Kaneguchi, A., Yamasaki, T., & Kito, N. (2024) · Respiratory Investigation · doi:10.1016/j.resinv.2024.06.009 · Cited by 5
Maximal inspiratory pressure and exercise-induced inspiratory muscle fatigue in chronic nonspecific low back pain
Klaps, S., Verbrugghe, J., Goossens, N., Meus, T., Köke, A. J. A., Verbunt, J., Langer, D., Timmermans, A. A. A., & Janssens, L. (2024) · Respiratory Medicine · doi:10.1016/j.rmed.2024.107887 · Cited by 6
Cardiorespiratory responses to exercise in CHF: a conspiracy of maladaptation
Dempsey, J. A. (2010) · The Journal of Physiology · doi:10.1113/jphysiol.2010.193805 · Cited by 5
Self-citation
Ergogenic value of oxygen supplementation in chronic obstructive pulmonary disease
Megaritis, D., Wagner, P., & Vogiatzis, I. (2022) · Internal and Emergency Medicine · doi:10.1007/s11739-022-03037-2 · Cited by 4
The management of chronic breathlessness
Evans, R. A., Spathis, A., Daynes, E., & Currow, D. C. (2022) · European Respiratory Society eBooks · doi:10.1183/2312508x.10013921 · Cited by 5
The effect of training with additional respiratory dead space on haematological elements of blood
Zatoń, M. W., Hebisz, R. G., & Hebisz, P. (2010) · Isokinetics and Exercise Science · doi:10.3233/ies-2010-0372 · Cited by 5
The equine diaphragm: A novel technique for repeatable ultrasound measurement
Fitzharris, L. E., Meehan, L. J., Hezzell, M., & Allen, K. (2020) · Veterinary Radiology & Ultrasound · doi:10.1111/vru.12903 · Cited by 5
Exciting perspectives for Translational Myology in the Abstracts of the 2018Spring PaduaMuscleDays: Giovanni Salviati Memorial – Chapter II - Abstracts of March 15, 2018
Carraro, U. (2018) · European Journal of Translational Myology · doi:10.4081/ejtm.2018.7364 · Cited by 5
Strength and Conditioning
Brown, L. E. (2017) · MDPI eBooks · doi:10.3390/books978-3-03842-347-8 · Cited by 5
Clinical Exercise Testing
Luks, A. M., & Glenny, R. W. (2015) · Elsevier eBooks · doi:10.1016/b978-1-4557-3383-5.00026-9 · Cited by 6
Respiratory and Muscle Oxygenation Responses to Two Constant-Load Exercise Intensities
Oueslati, F., Girard, O., & Ahmaidi, S. (2018) · Journal of Athletic Enhancement · doi:10.4172/2324-9080.1000296 · Cited by 5
Muscle metaboreflex activation via postexercise ischemia increases intercostal muscle blood flow index without evidence of local vasoconstriction in humans
Ichinose, M., Nakabayashi, M., & Ono, Y. (2025) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00577.2025 · Cited by 4
Regulated Monosyllabic Talk Test vs. Counting Talk Test During Incremental Cardiorespiratory Exercise: Determining the Implications of the Utterance Rate on Exercise Intensity Estimation
Mahmod, S. R., Narayanan, L. T., Hasan, R. A., & Supriyanto, E. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.832647 · Cited by 4
The effect of proportional assist ventilation on the electrical activity of the human diaphragm during exercise
Gerson, E. A. M., Dominelli, P. B., Leahy, M. G., Kipp, S., Guenette, J. A., Archiza, B., & Sheel, A. W. (2022) · Experimental Physiology · doi:10.1113/ep090808 · Cited by 4
The effect of a pressure ventilatory support on quadriceps endurance is maintained after exercise training in severe COPD patients. A longitudinal randomized, cross over study
Labeix, P., Fortune, I. C., Muti, D., Berger, M., Chomette-Ballereau, S., Barthélemy, J., Féasson, L., & Costes, F. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.1055023 · Cited by 4
Differential effects of exercise intensity and tolerable duration on exercise-induced diaphragm and expiratory muscle fatigue
Hardy, T. A., Chadwick, M. R., Ferguson, C., Cross, T. J., & Taylor, B. J. (2024) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00007.2024 · Cited by 4
Non-Invasive Ventilation Applied for Recovery from Exercise-Induced Diaphragmatic Fatigue
Kabitz, H., Walker, D., Prettin, S., Walterspacher, S., Sonntag, F., Dreher, M., & Windisch, W. (2008) · The Open Respiratory Medicine Journal · doi:10.2174/1874306400802010016 · Cited by 4
Metabolic and muscular factors limiting aerobic exercise in obese subjects
Vaccari, F., Floreani, M., Tringali, G., Micheli, R. D., Sartório, A., & Lazzer, S. (2019) · European Journal of Applied Physiology · doi:10.1007/s00421-019-04167-w · Cited by 4
Long-Term Benefits of Tailored Exercise in Severe Sarcoidosis: A Case Report
Herrera-Olivares, A. M., Manso, J. M. G., Rodríguez‐Gómez, I., Ara, I., Lucía, A., & Santalla, A. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17249512 · Cited by 4
The cardiovascular consequences of fatiguing expiratory muscle work in otherwise resting healthy humans
Hardy, T. A., Paula‐Ribeiro, M., Silva, B. M., Lyall, G. K., Birch, K. M., Ferguson, C., & Taylor, B. J. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00116.2020 · Cited by 4
Acute psychophysiological responses during exercise while using resistive respiratory devices: A systematic review.
López-Pérez, M. E., Romero‐Arenas, S., García, M. A. G., Colomer‐Poveda, D., & Márquez, G. (2022) · Physiology & Behavior · doi:10.1016/j.physbeh.2022.113968 · Cited by 4
Monitoring Changes in Oxygen Muscle during Exercise with High-Flow Nasal Cannula Using Wearable NIRS Biosensors
Briceño, F. A. C., Espinosa‐Ramírez, M., Rivera-Greene, A., Guerra-Venegas, C., Lungenstrass-Poulsen, A., Villagra-Reyes, V., Caulier‐Cisterna, R., Araneda, O. F., & Viscor, G. (2023) · Biosensors · doi:10.3390/bios13110985 · Cited by 4
The Influence of Lung Function and Respiratory Muscle Strength on Quadriceps Muscle Fatigability in COPD Patients Under Long-term Oxygen Therapy
Paneroni, M., Cavicchia, A., Salvi, B., Bertacchini, L., Venturelli, M., & Vitacca, M. (2024) · Archivos de Bronconeumología · doi:10.1016/j.arbres.2024.04.004 · Cited by 4
Intolérance à l’effort de la personne obèse : modalités d’évaluation et conséquences pour la prescription de l’activité physique
Mendelson, M., Michallet, A. S., Tonini, J., Favre‐Juvin, A., Guinot, M., Bricout, V., Wuyam, B., & Flore, P. (2012) · Obésité · doi:10.1007/s11690-012-0344-7 · Cited by 4
Has the Golden Age of Equine Exercise Physiology Passed and if so, Have We Answered All the Big Questions?
Marlin, D. (2015) · Journal of Equine Veterinary Science · doi:10.1016/j.jevs.2015.03.006 · Cited by 4
Progressive arteriolar vasoconstriction and fatigue during tetanic contractions of rat skeletal muscle are inhibited by α-receptor blockade
Inagaki, T., Sonobe, T., Poole, D. C., & Kano, Y. (2011) · The Journal of Physiological Sciences · doi:10.1007/s12576-011-0134-2 · Cited by 4
Diaphragm: The Relationship between Blood Supply Regulation and Characteristics of the Contractile Function
Borzykh, A. A., Виноградова, О. Л., & Tarasova, O. S. (2020) · Moscow University Biological Sciences Bulletin · doi:10.3103/s0096392520020029 · Cited by 4
Repeated-sprint training with low lung volume voluntary hypoventilation performed continuously throughout each set in healthy females
Devantay, L., Millet, G. P., & Raberin, A. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2025.1713797 · Cited by 3
Load carriage physiology in normoxia and hypoxia
Baur, D., Baur, K. G., Buchanan, B. K., Ortiz, M. J., & Doody, A. G. (2023) · European Journal of Applied Physiology · doi:10.1007/s00421-023-05320-2 · Cited by 4
The Respiratory System during Intermittent-Sprint Work: Respiratory Muscle Work and the Critical Distribution of Oxygen
Rodriguez, R. F., Aughey, R. J., & Billaut, F. (2020) · IntechOpen eBooks · doi:10.5772/intechopen.91207 · Cited by 3
Combined influence of inspiratory loading and locomotor subsystolic cuff inflation on cardiovascular responses during submaximal exercise
Smith, J. R., Bruhn, E. J., Berg, J., Nur, A. A., Villarraga, N., & Olson, T. P. (2020) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00781.2019 · Cited by 3
The Effect of Preexercise Expiratory Muscle Loading on Exercise Tolerance in Healthy Men
Hardy, T. A., How, S. C., & Taylor, B. J. (2020) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002468 · Cited by 3
Acute respiratory muscle unloading improves time-to-exhaustion during moderate- and heavy-intensity cycling in obese adolescent males
Alemayehu, H. K., Salvadego, D., Tringali, G., Micheli, R. D., Caccavale, M., Sartório, A., & Grassi, B. (2020) · Scientific Reports · doi:10.1038/s41598-020-74240-4 · Cited by 3
Exertional dyspnea associated with chest wall strapping is reduced when external dead space substitutes for part of the exercise stimulus to ventilation
Garske, L. A., Lal, R., Stewart, I. B., Morris, N. R., Cross, T. J., & Adams, L. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00051.2016 · Cited by 3
Resting limb muscle perfusion during inspiratory muscle loading in hypoxia and normoxia
Klenze, H., Köhler, T. C., Farquharson, F., Walterspacher, S., Duerschmied, D., Röecker, K., Kabitz, H., & Walker, D. (2017) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2017.06.003 · Cited by 3
The Effects of N-Acetylcysteine on Respiratory Muscle Fatigue During Heavy Exercise
Kelly, M. K., Wicker, R. J., Barstow, T. J., & Harms, C. A. (2008) · Medicine & Science in Sports & Exercise · doi:10.1249/01.mss.0000323641.38730.7e · Cited by 3
Passive limb movement augments ventilatory response to CO2 via sciatic inputs in anesthetized rats
Zhuang, J., Xu, F., Zhang, C., & FRAZIER, D. T. (2009) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2009.04.004 · Cited by 3
Effects of incremental cardiorespiratory exercise on the speech rate and the estimated exercise intensity using the counting talk test
Mahmod, S. R., Narayanan, L. T., & Supriyanto, E. (2018) · Journal of Physical Therapy Science · doi:10.1589/jpts.30.933 · Cited by 3
Blood pressure and limb blood flow responses during hyperpnoea are not affected by menstrual cycle phase in young women
Shimizu, K., Shiozawa, K., Ishida, K., Saito, M., Mizuno, S., Akima, H., & Katayama, K. (2020) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2020.103387 · Cited by 3
Work of Breathing During Exercise: Implications for Performance
Romer, L. M., & Dempsey, J. A. (2014) · Springer eBooks · doi:10.1007/978-88-470-5647-3_2 · Cited by 3
Self-citation
Strength and Conditioning
(2014) · Human Kinetics eBooks · doi:10.5040/9781718218727.part-004 · Cited by 3
Influence of an inspiratory muscle fatigue protocol on older adults on respiratory muscle strength and heart rate variability. A randomized controlled trial
Ladriñán-Maestro, A., Sánchez-Infante, J., Martín-Vera, D., del-Blanco-Muñiz, J. Á., Merino‐Andrés, J., & Sánchez‐Sierra, A. (2024) · Frontiers in Neuroscience · doi:10.3389/fnins.2024.1423927 · Cited by 2
Influence of the combination of end-expiratory breath-hold training and inspiratory muscle training on performance in artistic swimmers
Guézennec, J., Correa, D., & Billaut, F. (2025) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2025-0247 · Cited by 2
Inspiratory muscle training improves exercise performance and breathing pattern during 6-min walking test in systemic sclerosis-associated interstitial lung disease
Vicenzi, M., Bellocchi, C., Deboeck, G., Beretta, L., Tobaldini, E., Montano, N., & Rodrigues, G. D. (2025) · ERJ Open Research · doi:10.1183/23120541.00659-2025 · Cited by 2
Effect Of Inspiratory Muscle Traınıng on Diaphragm Functıon and Activıty Performance in Subacute Ischemıc Stroke Patıents: A Sıngle-Blind Randomized-Controlled Trial
Akcay, S., Akyol, D. K., Erkut, Ü., Coşkunsu, D. K., Kunduracılar, Z., Bajrami, A., & Yavaş, A. D. (2026) · Neurorehabilitation and neural repair · doi:10.1177/15459683251412282 · Cited by 2
Acute Cardiopulmonary and Muscle Oxygenation Responses to Normocapnic Hyperpnea Exercise in COPD
OUESLATI, F., Saey, D., Vézina, F.-A., NADREAU, É., MARTIN, M., & MALTAIS, F. (2021) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000002760 · Cited by 2
CO 2 -Enriched Air Inhalation Modulates the Ventilatory and Metabolic Responses of Endurance Runners During Incremental Running in Hypobaric Hypoxia
Cao, Y., Fujii, N., Fujimoto, T., Lai, Y., Ogawa, T., Hiroyama, T., Enomóto, Y., & Nishiyasu, T. (2022) · High Altitude Medicine & Biology · doi:10.1089/ham.2021.0114 · Cited by 2
Cardiopulmonary Exercise Performance of Children Born Non-Extremely Preterm
Fouzas, S., Nourloglou, A., Vervenioti, A., Karatza, A., Anthracopoulos, M. Β., & Dimitriou, G. (2024) · Children · doi:10.3390/children11020198 · Cited by 2
Physiological effects of high-flow nasal cannula during sustained high-intensity exercise in healthy volunteers: a randomised crossover trial
Moya-Gallardo, E., García-Valdés, P., Marambio-Coloma, C., Gutierrez-Escobar, C., Hernández-Vargas, B., Muñoz-Castro, C., Riquelme-Sánchez, S., Moo-Millan, J. I., Basoalto, R., Bruhn, A. R., et al. (2024) · ERJ Open Research · doi:10.1183/23120541.00482-2024 · Cited by 2
Ageing exacerbates the adverse effects of respiratory muscle fatigue on vascular function, locomotor muscle fatigue and exercise performance in males
Mons, V., Lavigne, C., Meste, O., Mauroy, B., & Blain, G. M. (2025) · Experimental Physiology · doi:10.1113/ep092897 · Cited by 2
The Effect of an Inspiratory Muscle Training Period at High Altitude on Arterial Oxygen Saturation and Performance of Iran’s National Team Endurance Runners
Rooholah, M. M., & Mirdar, S. (2016) · Journal of Pulmonary & Respiratory Medicine · doi:10.4172/2161-105x.1000356 · Cited by 2
Comparison of Respiratory Parameters of Physically Disabled and Healthy Children
Muammer, R., Baktır, S., & Muammer, K. (2015) · Bezmialem Science · doi:10.14235/bs.2015.392 · Cited by 2
Does altitude level of a prior time‐trial modify subsequent exercise performance in hypoxia and associated neuromuscular responses?
Girard, O., Bula, S., Faiss, R., Brocherie, F., Millet, G. Y., & Millet, G. P. (2016) · Physiological Reports · doi:10.14814/phy2.12804 · Cited by 2
Highlights from the 2018 European Respiratory Society International Congress: sleep and clinical physiology
Almendros, I., Baillieul, S., Caballero, C., Degani‐Costa, L. H., Furian, M., Hirotsu, C., Louvaris, Z., Thiel, S., & Turnbull, C. D. (2019) · ERJ Open Research · doi:10.1183/23120541.00201-2018 · Cited by 2
Efeitos do treinamento físico aeróbico associado ao treinamento respiratório no controle neurovascular e na força muscular respiratória em pacientes com insuficiência cardíaca
Trevizan, P. F. (2017) · doi:10.11606/t.5.2017.tde-20062017-151204 · Cited by 2
Physical Exercise in Post-Polio Syndrome: Highlights
Anna, M. D. S. (2018) · Biomedical Journal of Scientific & Technical Research · doi:10.26717/bjstr.2018.10.001953 · Cited by 1
Potential adverse effects of face mask use on cardiopulmonary function and thermoregulation in robotic stroke rehabilitation during the COVID-19 pandemic
Kwon, Y.-D., Park, C., Oh, W., & You, J. H. (2023) · Neurorehabilitation · doi:10.3233/nre-230150 · Cited by 1
The Relationship between Inspiratory Muscle Strength and Cycling Performance: Insights from Hypoxia and Inspiratory Muscle Warm-Up
Oliveira, A. L. M. B., Rodrigues, G. D., Rohan, P. D. A., Gonçalves, T. R., & Soares, P. P. D. S. (2024) · Journal of Functional Morphology and Kinesiology · doi:10.3390/jfmk9020097 · Cited by 1
Respiratory muscle endurance training among patients with chronic diseases: A systematic review of available evidence
Laurent, H., Costes, F., Richard, R., & Filaire, M. (2025) · Experimental Physiology · doi:10.1113/ep092300 · Cited by 1
Would Integrating Inspiratory Muscle Training into Pulmonary Rehabilitation of Adults with Burn Injuries Have Any Advantageous Effects? a Randomized, Double-Blind, Sham-controlled Study
Abdel‐Aal, N. M., Basha, M. A., Aloraini, S. M., Azab, A. R., & Kamel, F. H. (2025) · Annals of Rehabilitation Medicine · doi:10.5535/arm.240092 · Cited by 1
Determinants of Exercise Capacity in Children and Adolescents with Asthma: A Comparative Case-Control Study
Kaya, M., Uçgun, H., Karaaslan, H. B. G., Kıykım, A. A., & Kulli, H. (2025) · Nigerian Journal of Clinical Practice · doi:10.4103/njcp.njcp_746_24 · Cited by 1
Inspiratory Muscle Training Included in Therapeutic and Training Regimens for Middle-Distance Runners
Okrzymowska, P., Maćkała, K., Kucharski, W., & Roźek-Piechura, K. (2025) · Journal of Clinical Medicine · doi:10.3390/jcm14093180 · Cited by 1
Combined effects of normobaric hypoxia and cold on respiratory system responses to high‐intensity exercise
Callovini, A., Fornasiero, A., Savoldelli, A., Dorelli, G., Decet, M., Bortolan, L., Pellegrini, B., & Schena, F. F. (2025) · Experimental Physiology · doi:10.1113/ep092468 · Cited by 1
Hypoxic exercise enhances post-exercise hypotension compared to normoxic exercise
Kim, T.-J., Jang, M.-H., Han, J.-H., Jung, H. C., & Kim, J.-H. (2025) · International Journal of Sports Medicine · doi:10.1055/a-2602-9020 · Cited by 1
Effects of oral, oronasal, and oronasal breathing with a decongested nose during incremental maximal exercise testing of well-trained endurance athletes: a randomized cross-over study
Bergqvist, J., Reite, F., Edin, F., Schiöler, L., Börjesson, M., Steinsvåg, S., Pettersson, S., & Hellgren, J. (2025) · Frontiers in Physiology · doi:10.3389/fphys.2025.1654725 · Cited by 1
An evidence-based multi-factorial model to predict the oxygen cost of ventilation during ramp-incremental cycle ergometry exercise
O'Malley, B. G., Robergs, R. A., Hrach, K., Vella, C. A., & Marks, D. W. (2026) · Frontiers in Physiology · doi:10.3389/fphys.2026.1702120 · Cited by 1
Respiratory muscle oxygen demand and cardiac output distribution during exercise: revisiting an underweighted mechanism of exercise intolerance in heart failure
Vignati, C., & Pezzuto, B. (2026) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00547.2026 · Cited by 1
Respiratory Muscle Blood Flow Measured by Near-Infrared Spectroscopy (NIRS) and Indocyanine Green Dye (ICG)
Louvaris, Z., Zakynthinos, S. G., & Vogiatzis, I. (2014) · Springer eBooks · doi:10.1007/978-88-470-5647-3_12 · Cited by 2
Exploration fonctionnelle à l’exercice (EFX) et dyspnée inattendue
Aguilaniu, B., Terce, G., & Wallaert, B. (2013) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2013.09.012 · Cited by 1

Authors: Dempsey, J. A., Romer, L., Rodman, J., Miller, J., & Smith, C.
Affiliations: University of Wisconsin–Madison (US)
Corresponding author: Dempsey, Jerome A.
ORCID: Dempsey, Jerome A.
Romer, Lee
Miller, Jordan
Smith, Curtis
Venue: Respiratory Physiology & Neurobiology
Publisher: Elsevier BV
Published: 2006-04
Volume: 151
Issue: 2-3
Pages: 242-250
ISSN: 1569-9048 (ISSN-L)
DOI: 10.1016/j.resp.2005.12.015
OpenAlex: W1973218442
Cited by: 398
References: 35
Citations by year: 2026: 23 · 2025: 22 · 2024: 19 · 2023: 18 · 2022: 28 · 2021: 23 · 2020: 34 · 2019: 26 · 2018: 26 · 2017: 22 · 2016: 14 · 2015: 18 · 2014: 14 · 2013: 9 · 2012: 22
FWCI: 3.84
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Respiratory Physiology & Neurobiology (publishedVersion)
PubMed (publishedVersion)
Funders: American Heart Association
National Heart, Lung, and Blood Institute
Topics: Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
Keywords: muscle metaboreflex, ventilatory response, central fatigue, peripheral fatigue, sympathetic vasoconstriction, chronic obstructive pulmonary disease, chronic heart failure, respiratory muscle work
MeSH terms: Animals, Humans, Models, Biological, Physical Endurance, Respiratory Muscles, Exercise, Muscle, Skeletal, Muscle Fatigue

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Consequences of exercise-induced respiratory muscle work

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks