Correlation analysis of the severity and clinical prognosis of 32 cases of patients with COVID-19
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Prominent pulmonary fibrosis was observed in this lung autopsy series and correlated with SOTD and patient age.
“Prominent pulmonary fibrosis was observed in this lung autopsy series, consistent with previous reports (49–51), and correlated with SOTD and patient age (fig. S17).”
From Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19 (2021) · cites this paper as [49]
Correlation analysis of the severity and clinical prognosis of patients with COVID-19 demonstrated that an increase in fibrosis indicators detected at hospital admission, including hyaluronic acid, laminin, and type III procollagen, was predictive of critical illness and poor prognosis.
“Correlation analysis of the severity and clinical prognosis of patients with COVID-19 demonstrated that an increase in fibrosis indicators detected at hospital admission, including hyaluronic acid, laminin, and type III procollagen, was predictive of critical illness and poor prognosis (49).”
From Lung epithelial and endothelial damage, loss of tissue repair, inhibition of fibrinolysis, and cellular senescence in fatal COVID-19 (2021) · cites this paper as [49]
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- Authors
- Ding, M., Zhang, Q., Li, Q., Wu, T., & Huang, Y.-Z.
- Affiliations
- Zhongda Hospital Southeast University (CN)
- Venue
- Respiratory Medicine
- Publisher
- Elsevier BV
- Published
- 2020-06
- Volume
- 167
- Pages
- 105981
- ISSN
- 0954-6111 (ISSN-L)
- PMC
- PMC7167578
- OpenAlex
- W3016832871
- Cited by
- 60
- References
- 11
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 6 · 2023: 7 · 2022: 13 · 2021: 17 · 2020: 15
- FWCI
- 1.71
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Respiratory Medicine (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Jiangsu Social Development Project (BE2017745)
- Topics
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › SARS-CoV-2 and COVID-19 Research
- Keywords
- COVID-19 pandemic, SARS-CoV-2, disease severity, clinical prognosis, prognostic factors, mortality
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, COVID-19 Testing, Aged, C-Reactive Protein, Female, Humans, Hyaluronic Acid, Male, Middle Aged, Pneumonia, Viral, Prognosis, Pulmonary Fibrosis, Retrospective Studies, Lung Diseases, Interstitial, Coronavirus Infections, Clinical Laboratory Techniques, Collagen Type XII, Pandemics
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