RNA recognition motifs: boring? Not quite

The sequence of the human genome

Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., Smith, H. O., Yandell, M., Evans, C. A., Holt, R. A., et al. (2001) · Science · doi:10.1126/science.1058040 · Cited by 13,909

Sequence-specific binding of single-stranded RNA: is there a code for recognition?

Auweter, S. D., Oberstrass, F. C., & Allain, F. H.-T. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl620 · Cited by 314

A brave new world of RNA-binding proteins

Hentze, M. W., Castello, A., Schwarzl, T., & Preiss, T. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.130 · Cited by 1,821

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

Tollervey, J. R., Curk, T., Rogelj, B., Briese, M., Cereda, M., Kayikci, M., König, J., Hortobágyi, T., Nishimura, A. L., Župunski, V., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2778 · Cited by 1,165

RBPDB: a database of RNA-binding specificities

Cook, K. B., Kazan, H., Zuberi, K., Morris, Q., & Hughes, T. R. (2011) · Nucleic Acids Research · doi:10.1093/nar/gkq1069 · Cited by 638

RNA Binding Protein Regulation and Cross-Talk in the Control of AU-rich mRNA Fate

García-Mauriño, S. M., Rivero-Rodríguez, F., Velázquez-Cruz, A., Hernández-Vellisca, M., Díaz-Quintana, A., De la Rosa, M. A., & Díaz-Moreno, I. (2017) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2017.00071 · Cited by 174

Current-generation high-throughput sequencing: deepening insights into mammalian transcriptomes

Blencowe, B. J., Ahmad, S., & Lee, L. J. (2009) · Genes & Development · doi:10.1101/gad.1788009 · Cited by 168

Emerging complexity of the HuD/ELAVl4 gene; implications for neuronal development, function, and dysfunction

Bronicki, L. M., & Jasmin, B. J. (2013) · RNA · doi:10.1261/rna.039164.113 · Cited by 126

One, Two, Three, Four! How Multiple RRMs Read the Genome Sequence

Afroz, T., Cienikova, Z., Cléry, A., & Allain, F. H. T. (2015) · Methods in Enzymology · doi:10.1016/bs.mie.2015.01.015 · Cited by 104

Spatiotemporally-resolved mapping of RNA binding proteins via functional proximity labeling reveals a mitochondrial mRNA anchor promoting stress recovery

Qin, W., Myers, S. A., Carey, D. K., Carr, S. A., & Ting, A. Y. (2021) · Nature Communications · doi:10.1038/s41467-021-25259-2 · Cited by 84

Human Inositol Polyphosphate Multikinase Regulates Transcript-Selective Nuclear MRNA Export to Preserve Genome Integrity

Wickramasinghe, V. O., Savill, J. M., Chavali, S., Jonsdottir, A. B., Rajendra, E., Grüner, T., Laskey, R. A., Babu, M. M., & Venkitaraman, A. R. (2013) · Molecular Cell · doi:10.1016/j.molcel.2013.08.031 · Cited by 80

Liquid-liquid phase transitions and amyloid aggregation in proteins related to cancer and neurodegenerative diseases

(2019) · Advances in protein chemistry and structural biology · doi:10.1016/bs.apcsb.2019.08.002 · Cited by 78

Structural analysis of Red1 as a conserved scaffold of the RNA-targeting MTREC/PAXT complex

Foucher, A.-E., Touat-Todeschini, L., Juarez-Martinez, A. B., Rakitch, A., Laroussi, H., Karczewski, C., Acajjaoui, S., Soler-López, M., Cusack, S., Mackereth, C. D., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-32542-3 · Cited by 26

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

(2024) · doi:10.7554/elife.98070.3 · Cited by 23

Mutagenesis and structural studies reveal the basis for the specific binding of SARS-CoV-2 SL3 RNA element with human TIA1 protein

Zhang, D., Qiao, L., Lei, X., Dong, X., Tong, Y., Wang, J., Wang, Z., & Zhou, R. (2023) · Nature Communications · doi:10.1038/s41467-023-39410-8 · Cited by 21

The Arabidopsis SR45 splicing factor bridges the splicing machinery and the exon–exon junction complex

(2024) · doi:10.1093/jxb/erae002 · Cited by 17

DTX3L ubiquitin ligase ubiquitinates single-stranded nucleic acids

(2024) · doi:10.7554/elife.98070 · Cited by 16

Challenges in Therapeutically Targeting the RNA‐Recognition Motif

Schmeing, S., & Hart, P. '. (2024) · WIREs RNA · doi:10.1002/wrna.1877 · Cited by 11

Structural and mechanistic analysis of covalent ligands targeting the RNA-binding protein NONO

Lindsey, G. L., Hockley, T. K., Gomez, A. V., Marshall, A. C., Brothers, W. R., Finney, C. T., Gross, J., Fox, A. H., Yeo, G. W., Melillo, B., et al. (2026) · Cell Chemical Biology · doi:10.1016/j.chembiol.2025.12.010 · Cited by 6

Insight into the Structural Basis for Dual Nucleic Acid—Recognition by the Scaffold Attachment Factor B2 Protein

Korn, S. M., Von Ehr, J., Dhamotharan, K., Tants, J.-N., Abele, R., & Schlundt, A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24043286 · Cited by 4

HIPPO: HIstogram-based Pseudo-POtential for scoring protein-ssRNA fragment-based docking poses

Kravchenko, A., de Vries, S. J., Smaïl-Tabbone, M., & Chauvot de Beauchene, I. (2024) · BMC Bioinformatics · doi:10.1186/s12859-024-05733-6 · Cited by 1

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA

Keil, P., Wulf, A., Kachariya, N., Reuscher, S., Hühn, K., Silbern, I., Altmüller, J., Stehle, R., Zarnack, K., Sattler, M., et al. (2022) · doi:10.1101/2022.07.22.501171