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Cited by 981

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

SF1 and SF2 helicases: family matters

Open access
Fairman-Williams, Margaret E, Guenther, Ulf-Peter, Jankowsky, Eckhard·2010·Current Opinion in Structural Biology

Abstract

Helicases of the superfamily (SF) 1 and 2 are involved in virtually all aspects of RNA and DNA metabolism. SF1 and SF2 helicases share a catalytic core with high structural similarity, but different enzymes even within each superfamily perform a wide spectrum of distinct functions on diverse substrates. To rationalize similarities and differences between these helicases, we outline a classification based on protein families that are characterized by typical sequence, structural and mechanistic features. This classification complements and extends existing SF1 and SF2 helicase categorizations and highlights major structural and functional themes for these proteins. We discuss recent data in the context of this unifying view of SF1 and SF2 helicases.

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Crossref · 10.1016/j.sbi.2010.03.011

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Metadata

Authors
Fairman-Williams, M. E., Guenther, U.-P., & Jankowsky, E.
Venue
Current Opinion in Structural Biology
Publisher
Elsevier BV
Published
2010-06
Volume
20
Issue
3
Pages
313-324
ISSN
0959-440X (ISSN-L)
OpenAlex
W2037978116
Cited by
981
References
3
FWCI
2.59
Type
journal article
Language
en
Open access
green

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