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Cited by 144Schizophrenia research and treatmentGlobal Cancer Incidence and ScreeningPsychopathy, Forensic Psychiatry, Sexual Offending

The DOI matches its Crossref record; 30 of the 32 references it cites were found in a registry or an index.

Risk for cancer in a cohort of patients hospitalized for schizophrenia in Denmark, 1969–1993

Dalton, Susanne Oksbjerg, Mellemkjær, Lene, Thomassen, Lars, Mortensen, Preben B., Johansen, Christoffer·2005·Schizophrenia Research
DOI 10.1016/j.schres.2004.11.009
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Abstract

We investigated the cancer risk of patients hospitalized for schizophrenia in a nationwide cohort study. All 22766 adults admitted for schizophrenia, ICD-8 295, in Denmark between 1969 and 1993 were followed up for cancer through 1995. The incidence of site-specific cancers was compared with national incidence rates, adjusted for sex, age and calendar time. The risk for cancer was increased for both men and women during the first year of follow-up. When the first year of follow-up was excluded, the risk for all tobacco-associated cancers and for prostate and rectal cancers was reduced for male patients with schizophrenia. The standardized incidence ratio (SIR) of lung cancer was marginally reduced (SIR, 0.86; 95% CI: 0.65, 1.02) for male patients with schizophrenia; this was due, however, to a reduction in risk for older patients. An increased risk for breast cancer found for female patients with schizophrenia (SIR, 1.20; 95% CI: 1.05, 1.38) should be interpreted with caution, given the high proportion of nulliparous women with schizophrenia in Denmark. The data might support reduced risks for prostate and rectal cancer among male patients with schizophrenia, whereas a changing smoking pattern might explain the reduced risk for tobacco-related cancers.

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Metadata

Authors
Dalton, S. O., Mellemkjær, L., Thomassen, L., Mortensen, P. B., & Johansen, C.
Affiliations
  • Danish Cancer Society (DK)
  • Aarhus University (DK)
Corresponding author
Dalton, Susanne Oksbjerg
ORCID
Venue
Schizophrenia Research
Publisher
Elsevier BV
Published
2005-06
Volume
75
Issue
2-3
Pages
315-324
ISSN
0920-9964 (ISSN-L)
DOI
10.1016/j.schres.2004.11.009
OpenAlex
W2090248954
Cited by
142
References
32
Citations by year
2026: 2 · 2025: 5 · 2024: 4 · 2023: 5 · 2022: 8 · 2021: 6 · 2020: 6 · 2019: 5 · 2018: 9 · 2017: 7 · 2016: 2 · 2015: 11 · 2014: 6 · 2013: 6 · 2012: 10
FWCI
1.67
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Schizophrenia Research (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Danmarks Grundforskningsfond
  • Fonds National de la Recherche Luxembourg
Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
  • Health Sciences › Medicine › Oncology › Global Cancer Incidence and Screening
  • Social Sciences › Psychology › Clinical Psychology › Psychopathy, Forensic Psychiatry, Sexual Offending
Keywords
schizophrenia, cancer risk
MeSH terms
Adolescent, Adult, Aged, Denmark, Female, Follow-Up Studies, Humans, Male, Middle Aged, Neoplasms, Risk Factors, Schizophrenia, Cohort Studies, Incidence

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