Cited by 210Schizophrenia research and treatmentMental Health and PsychiatryNeurotransmitter Receptor Influence on Behavior

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Endophenotypes in schizophrenia: A selective review

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Allen, Allyssa J., Griss, Mélina E., Folley, Bradley S., Hawkins, Keith A., Pearlson, Godfrey D.·2009·Schizophrenia Research

DOI 10.1016/j.schres.2009.01.016PMC PMC2665704

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Abstract

Background Given the wealth of data in the literature on schizophrenia endophenotypes, it is useful to have one source to reference their frequency data. We reviewed the literature on disease-liability associated variants in structural and functional magnetic resonance images (MRI), sensory processing measures, neuromotor abilities, neuropsychological measures, and physical characteristics in schizophrenia patients (SCZ), their first-degree relatives (REL), and healthy controls (HC). The purpose of this review was to provide a summary of the existing data on the most extensively published endophenotypes for schizophrenia.Methods We searched PubMed and MedLine for all studies on schizophrenia endophenotypes comparing SCZ to HC and/or REL to HC groups. Percent abnormal values, generally defined as >2 SD from the mean (in the direction of abnormality) and/or associated effect sizes (Cohen's d) were calculated for each study.Results Combined, the articles reported an average 39.4% (SD=20.7%; range=2.2-100%) of abnormal values in SCZ, 28.1% (SD=16.6%; range=1.6-67.0%) abnormal values in REL, and 10.2% (SD=6.7%; range=0.0-34.6%) in HC groups.Conclusions These findings are reviewed in the context of emerging hypotheses on schizophrenia endophenotypes, as well as a discussion of clustering trends among the various intermediate phenotypes. In addition, programs for future research are discussed, as instantiated in a few recent large-scale studies on multiple endophenotypes across patients, relatives, and healthy controls.

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Items 201–272 of 272

Cognitive functions related to interpersonal problem-solving skills in schizophrenic patients compared with healthy subjects
Zanello, A., Perrig, L., & Huguelet, P. (2006) · Psychiatry Research · doi:10.1016/j.psychres.2003.07.009 · Cited by 60
Semantic matching of pictures in schizophrenia: A cross-cultural ERP study
Bobes, M. A., Xiao, L., Ibáñez, S., Hou, Y., & Valdés-Sosa, M. J. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00352-5 · Cited by 60
Deficient motor synchrony in schizophrenia.
Manschreck, T. C., Maher, B. A., Rucklos, M. E., Veneer, D. R., & Ader, D. N. (1981) · Journal of Abnormal Psychology · doi:10.1037//0021-843x.90.4.321 · Cited by 59
Minor physical anomalies in familial and sporadic schizophrenia: the Maudsley family study
Griffiths, T. D., Sigmundsson, T., Takei, N., Frangou, S., Birkett, P., Sharma, T., Reveley, A. M., & Murray, R. M. (1998) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.64.1.56 · Cited by 59
Application of automated MRI volumetric measurement techniques to the ventricular system in schizophrenics and normal controls
Shenton, M. E., Kikinis, R., McCarley, R. W., Metcalf, D., Tieman, J., & Jolesz, F. A. (1991) · Schizophrenia Research · doi:10.1016/0920-9964(91)90037-r · Cited by 58
Use of Serotonergic Drugs and the Risk of Bleeding
Verdel, B. M., Souverein, P. C., Meenks, S. D., Heerdink, E. R., Leufkens, H. G. M., & Egberts, T. C. G. (2010) · Clinical Pharmacology & Therapeutics · doi:10.1038/clpt.2010.240 · Cited by 57
Schizophrenia with onset after age 50 years
Brodaty, H., Sachdev, P. S., Rose, N., Rylands, K., & Prenter, L. (1999) · The British Journal of Psychiatry · doi:10.1192/bjp.175.5.410 · Cited by 57
Early detection of schizophrenia by diffusion weighted imaging
DeLisi, L. E., Szulc, K. U., Bertisch, H. C., Majcher, M., Brown, K., Bappal, A., Branch, C. A., & Ardekani, B. A. (2006) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2006.04.010 · Cited by 57
Nonverbal working memory deficits in schizophrenia patients: Evidence of a supramodal executive processing deficit
Gooding, D. C. (2003) · Schizophrenia Research · doi:10.1016/j.schres.2003.07.007 · Cited by 56
Sustained attention in young people at high risk for schizophrenia
Cosway, R., Byrne, M., Clafferty, R. A., Hodges, A., Grant, L., MORRIS, J., Abukmeil, S. S., LAWRIE, S. M., Miller, P. M., Owens, D. G. C., et al. (2002) · Psychological Medicine · doi:10.1017/s0033291701005050 · Cited by 56
In this issue of The American Journal of Psychiatry
Kulynych, J. J., Vladar, K., Jones, D. W., & Weinberger, D. R. (1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.9.a50 · Cited by 54
Superior temporal gyrus volume in schizophrenia: a study using MRI morphometry assisted by surface rendering
(1996) · American Journal of Psychiatry · doi:10.1176/ajp.153.1.50 · Cited by 53
Large CSF Volume Not Attributable to Ventricular Volume in Schizotypal Personality Disorder
Dickey, C. C., Shenton, M. E., Hirayasu, Y., Fischer, I. A., Voglmaier, M. M., Niznikiewicz, M. A., Seidman, L. J., Fraone, S., & McCarley, R. W. (2000) · American Journal of Psychiatry · doi:10.1176/ajp.157.1.48 · Cited by 52
Failure to Find P50 Suppression Deficits in Young First-Episode Patients With Schizophrenia and Clinically Unaffected Siblings
Wilde, O. B.-D., Bour, L. J., Dingemans, P. M. A. J., Koelman, J. H. T. M., & LINSZEN, D. H. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbm001 · Cited by 52
Abnormal association between reduced magnetic mismatch field to speech sounds and smaller left planum temporale volume in schizophrenia
Yamasue, H., Yamada, H., Yumoto, M., Kamio, S., Kudo, N., Uetsuki, M., Abe, O., Fukuda, R., Aoki, S., Ohtomo, K., et al. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.01.042 · Cited by 51
No deficit in Wisconsin Card Sorting Test performance of schizophrenic patients' first-degree relatives
Stratta, P., Daneluzzo, E., Mattei, P., Bustini, M., CASACCHIA, M., & Rossi, A. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00047-9 · Cited by 49
Clinical subtyping reveals significant differences in calcium-dependent phospholipase A2 activity in schizophrenia
Hudson, C. J., Gotowiec, A. P., Seeman, M. V., Warsh, J. J., & Ross, B. M. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00010-4 · Cited by 49
Quantitative characterization of eye tracking dysfunction in schizophrenia
Levy, D. L., Lajonchere, C., Dorogusker, B., Min, D., Lee, S., Tartaglini, A., Lieberman, J. A., & Mendell, N. R. (2000) · Schizophrenia Research · doi:10.1016/s0920-9964(99)00122-x · Cited by 47
Specificity of smooth pursuit eye movement and visual fixation abnormalities in schizophrenia
AMADOR, X. F., Sackeïm, H. A., Mukherjee, S., Halperin, R., Neeley, P., Maclin, E. L., & Schnur, D. B. (1991) · Schizophrenia Research · doi:10.1016/0920-9964(91)90040-x · Cited by 46
Familial Aggregation in Skin Flush Response to Niacin Patch Among Schizophrenic Patients and Their Nonpsychotic Relatives
Lin, S., Liu, C., Chang, S., Hwu, H., Liu, S., Hwang, T., Hsieh, M. H., Guo, S.-C., & Chen, W. J. (2006) · Schizophrenia Bulletin · doi:10.1093/schbul/sbl038 · Cited by 46
Functional Genomics and Schizophrenia: Endophenotypes and Mutant Models
Waddington, J. L., Corvin, A. P., Donohoe, G. J., O’Tuathaigh, C. M. P., Mitchell, K. J., & Gill, M. (2007) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2007.04.011 · Cited by 45
Choice of Comparison Group and Findings of Computerised Tomography in Schizophrenia
Smith, G. N., Iacono, W. G., Moreau, M., Tallman, K., Beiser, M., & Flak, B. (1988) · The British Journal of Psychiatry · doi:10.1192/bjp.153.5.667 · Cited by 44
Spatial and object working memory impairments in schizophrenia patients: A Bayesian item-response theory analysis.
Coleman, M. J., Cook, S., Matthysse, S., Barnard, J., Lo, Y., Levy, D. L., Rubin, D. B., & Holzman, P. S. (2002) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.111.3.425 · Cited by 44
Deficient motor synchrony in schizophrenia.
Manschreck, T. C., Maher, B. A., Rucklos, M. E., et al. (1981) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.90.4.321 · Cited by 44
Handedness in first-episode psychotic patients and their first-degree biological relatives.
Clementz, B. A., Iacono, W. G., & Beiser, M. (1994) · Journal of Abnormal Psychology · doi:10.1037/0021-843x.103.2.400 · Cited by 42
Failure to find progressive temporal lobe volume decreases 10 years subsequent to a first episode of schizophrenia
DeLisi, L. E., & Hoff, A. L. (2005) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2005.02.005 · Cited by 42
Are eye movement abnormalities indicators of genetic vulnerability to schizophrenia?
Boudet, C., Bocca, M., Chabot, B., Delamillieure, P., Brazo, P., Denise, P., & Dollfus, S. (2005) · European Psychiatry · doi:10.1016/j.eurpsy.2004.12.010 · Cited by 40
Semantic Dysfunction in Women With Schizotypal Personality Disorder
Niznikiewicz, M. A., Shenton, M. E., Voglmaier, M. M., Nestor, P. G., Dickey, C. C., Frumin, M., Seidman, L. J., Allen, C. G., & McCarley, R. W. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1767 · Cited by 39
Re-examining handedness in schizophrenia: Now you see it - now you don't
Nelson, L. D., Satz, P., Green, M. M., & Cicchetti, D. V. (1993) · Journal of Clinical and Experimental Neuropsychology · doi:10.1080/01688639308402553 · Cited by 38
Quantitative EEG, SPEM, and Psychometric Studies in Schizophrenics before and during Differential Neuroleptic Therapy
Saletu, B., Kufferle, B., Grünberger, J., & Anderer, P. (1986) · Pharmacopsychiatry · doi:10.1055/s-2007-1017283 · Cited by 37
Association of an oculomotor delayed response task and the Wisconsin Card Sort Test in schizophrenic patients
Park, S. (1997) · International Journal of Psychophysiology · doi:10.1016/s0167-8760(97)00045-7 · Cited by 37
The ‘well control’ artefact in case/control studies of specific psychiatric disorders
Schwartz, S., & Link, B. G. (1989) · Psychological Medicine · doi:10.1017/s0033291700024338 · Cited by 36
Educational level and age influence spatial working memory and Wisconsin Card Sorting Test performance differently: a controlled study in schizophrenic patients
Stratta, P., Prosperini, P., Daneluzzo, E., Bustini, M., & Rossi, A. (2001) · Psychiatry Research · doi:10.1016/s0165-1781(01)00230-x · Cited by 36
WCST performance and schizotypal features in the first-degree relatives of patients with schizophrenia
Laurent, A., Duly, D., Murry, P., Foussard, N., Boccara, S., Mingat, F., Jean Dalery, A., & d’Amato, T. (2001) · Psychiatry Research · doi:10.1016/s0165-1781(01)00306-7 · Cited by 35
The Wisconsin card sorting test discriminates schizophrenic patients and their siblings
Scarone, S., Abbruzzese, M., & Gambini, O. (1993) · Schizophrenia Research · doi:10.1016/0920-9964(93)90044-j · Cited by 34
Morphometry of the Superior Temporal Plane In Schizophrenia: Relationship to Clinical Correlates
Crespo‐Facorro, B., Kim, J., Chemerinski, E., Magnotta, V. A., Andreasen, N. C., & Nopoulos, P. (2004) · Journal of Neuropsychiatry · doi:10.1176/jnp.16.3.284 · Cited by 34
Superior temporal gyrus and P300 in schizophrenia: a combined ERP/structural magnetic resonance imaging investigation
Meisenzahl, E. M., Frodl, T., Müller, D. K., Schmitt, G., Gallinat, J., Zetzsche, D. A., Marcuse, A., Juckel, G., Leinsinger, G., Hahn, K. M., et al. (2003) · Journal of Psychiatric Research · doi:10.1016/s0022-3956(03)00078-5 · Cited by 33
An assessment of the Wisconsin Card Sorting Test as an indicator of liability to schizophrenia
Battaglia, M., Abbruzzese, M., Ferri, S., Scarone, S., Bellodi, L., & Smeraldi, E. (1994) · Schizophrenia Research · doi:10.1016/0920-9964(94)90007-8 · Cited by 33
Independent Domains of Inhibitory Gating in Schizophrenia and the Effect of Stimulus Interval
Hong, L. E., Summerfelt, A. T., Wonodi, I., Adami, H. M., Buchanan, R. W., & Thaker, G. K. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.1.61 · Cited by 33
Attention, eye tracking and schizophrenia
Acker, W. B., & Toone, B. (1978) · British Journal of Social and Clinical Psychology · doi:10.1111/j.2044-8260.1978.tb00261.x · Cited by 32
In search of madness: schizophrenia and neuroscience
(2001) · Choice Reviews Online · doi:10.5860/choice.39-1239 · Cited by 32
Mixed-Handedness in Patients with Functional Psychosis
Malesu, R. R., Cannon, M. D., Jones, P. B., McKenzie, K. J., Gilvarry, K., Rifkin, L., Toone, B., & Murray, R. M. (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.168.2.234 · Cited by 31
Spatial working memory: absence of gender differences in schizophrenia patients and healthy control subjects
Minor, K. L., & Park, S. (1999) · Biological Psychiatry · doi:10.1016/s0006-3223(99)00149-3 · Cited by 31
Soft signs of neurological dysfunction in schizophrenia: an investigation of lateral performance.
Walker, E. F., & Green, M. (1982) · PubMed · Cited by 30
Ventriculomegaly in schizophrenia: Is the choice of controls important?
Raz, S., Raz, N., & Bigler, E. D. (1988) · Psychiatry Research · doi:10.1016/0165-1781(88)90142-4 · Cited by 29
Clinical and experimental characteristics of “hypothetically psychosis prone” college students
Cadenhead, K. S., Kumar, C. T. S., & BRAFF, D. L. (1996) · Journal of Psychiatric Research · doi:10.1016/0022-3956(96)00020-9 · Cited by 28
Eye tracking, schizophrenic symptoms, and schizotypal personality disorder
Keefe, R. S. E., Siever, L. J., Mohs, R. C., Peterson, A. E., Mahon, T. R., Bergman, R. L., & Davis, K. L. (1989) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/bf01739742 · Cited by 27
Discriminating Value of Total Minor Physical Anomaly Score on the Waldrop Physical Anomaly Scale Between Schizophrenia Patients and Normal Control Subjects
Sivkov, S. T., & Akabaliev, V. (2004) · Schizophrenia Bulletin · doi:10.1093/oxfordjournals.schbul.a007085 · Cited by 27
Non-selective impairment of Wisconsin Card Sorting Test performance in patients with schizophrenia
Dieci, M., Vita, A., Silenzi, C., Caputo, A., Comazzi, M., Ferrari, L., Ghiringhelli, L., Mezzetti, M., Tenconi, F., & INVERNIZZI, G. (1997) · Schizophrenia Research · doi:10.1016/s0920-9964(96)00125-9 · Cited by 27
SUSTAINED ATTENTION DEFICIT IN YOUNG SCHIZOPHRENIC AND SCHIZOTYPIC MEN
Obiols, J. E., Clos, M., Corberó, E., García-Domingo, M., de Trinchería, I., & Llaberia, E. D. (1992) · Psychological Reports · doi:10.2466/pr0.1992.71.3f.1131 · Cited by 25
Combined measure of smooth pursuit eye movements and ventricle-brain ratio in schizophrenic disorders
Smeraldi, E., Gambini, O., Bellodi, L., Sacchetti, E., Vita, A., Rosa, M., Macciardi, F. M., & Cazzullo, C. L. (1987) · Psychiatry Research · doi:10.1016/0165-1781(87)90012-6 · Cited by 24
Relationship of good and poor Wisconsin Card Sorting Test performance to illness duration in schizophrenia: a cross-sectional analysis
Stratta, P., Arduini, L., Daneluzzo, E., Rinaldi, O., Genova, A. D., & Rossi, A. (2003) · Psychiatry Research · doi:10.1016/s0165-1781(03)00256-7 · Cited by 24
Sensorimotor laterality in schizophrenia: Which features transcend cultural influences?
Gureje, O. (1988) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1988.tb05099.x · Cited by 24
Narrow and Broad Definition of Mixed-Handedness in Male Psychiatric Patients
Giotakos, O. (2001) · Perceptual and Motor Skills · doi:10.2466/pms.2001.93.3.631 · Cited by 22
Smooth pursuit eye movements of normal and schizophrenic subjects tracking an unpredictable target
Allen, J. S., Matsunaga, K., Hacısalihzade, S. S., & STARK, L. W. (1990) · Biological Psychiatry · doi:10.1016/0006-3223(90)90457-d · Cited by 22
Does the Definition of Borders of the Planum Temporale Influence the Results in Schizophrenia?
Meisenzahl, E. M., Zetzsche, T., Preuss, U. W., Frodl, T., Leinsinger, G. L., & Möller, H. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.7.1198 · Cited by 22
Endophenotypes, Dimensions, Risks: Is Psychosis Analogous to Common Inherited Medical Illnesses?
Pearlson, G. D., & Folley, B. S. (2008) · Clinical EEG and Neuroscience · doi:10.1177/155005940803900210 · Cited by 21
Self-citation
Non-Right-Handedness and Obstetrical Complications in Paranoid Hallucinatory Schizophrenics
Sperling, W., Martus, P., & Barocka, A. (1999) · Psychopathology · doi:10.1159/000029099 · Cited by 21
Hand preference in patients with allergy, juvenile cancer, and schizophrenia
Upadhyay, N., Mandal, M., Asthana, A. K., & Sharma, H. O. (2004) · Laterality Asymmetries of Body Brain and Cognition · doi:10.1080/13576500342000194 · Cited by 21
Relationships of categorization on tests and daily tasks in patients with schizophrenia, post-stroke patients and healthy controls
Josman, N., & Katz, N. (2005) · Psychiatry Research · doi:10.1016/j.psychres.2004.03.015 · Cited by 20
Saccadic distractibility is elevated in schizophrenia patients, but not in their unaffected relatives
MacCabe, J. H., SIMON, H., Zanelli, J., Walwyn, R. E. A., McDonald, C., & Murray, R. M. (2005) · Psychological Medicine · doi:10.1017/s0033291705005738 · Cited by 20
Homozygous mutation (A228T) in the 5?-reductase type 2 gene in a boy with 5?-reductase deficiency: Genotype-phenotype correlations
Nordenskj�ld, A., Magnus, �., Aagen�s, �., & Knudtzon, J. (1998) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(19981116)80:3 · Cited by 19
Vestibular activation, smooth pursuit tracking, and psychosis
Jones, A. M., & Pivik, R. T. (1985) · Psychiatry Research · doi:10.1016/0165-1781(85)90097-6 · Cited by 19
Normal eye tracking is associated with abnormal morphology of medial temporal lobe structures in schizophrenia
Levy, D. L., Bogerts, B., Degreef, G., Dorogusker, B., WATERNAUX, C. M., Ashtari, M., Jody, D. N., Geisler, S., & Lieberman, J. A. (1992) · Schizophrenia Research · doi:10.1016/0920-9964(92)90055-a · Cited by 15
Inverse Relationship of Perinatal Complications and Eye Tracking Dysfunction in Relatives of Patients With Schizophrenia: Evidence for a Two-Factor Model
Kinney, D. K., Levy, D. L., Yurgelun-Todd, D. A., Tramer, S. J., & Holzman, P. S. (1998) · American Journal of Psychiatry · doi:10.1176/ajp.155.7.976 · Cited by 14
The Wisconsin Card Sort Test and P300 responses to novel auditory stimuli in schizophrenic patients
Merrin, E. L., Floyd, T. C., Deicken, R. F., & Lane, P. A. (2005) · International Journal of Psychophysiology · doi:10.1016/j.ijpsycho.2005.05.012 · Cited by 12
Auditory Recognition Memory, Conscious Recollection, and Executive Function in Patients with Schizophrenia
Drakeford, J. L., Edelstyn, N. M. J., Oyebode, F., Srivastava, S., Calthorpe, W. R., & Mukherjee, T. (2006) · Psychopathology · doi:10.1159/000093524 · Cited by 11
Spatial working memory assessment by a visual-manual delayed response task: a controlled study in schizophrenia
Stratta, P., Daneluzzo, E., Prosperini, P., Bustini, M., Marinangeli, M. G., & Rossi, A. (1999) · Neuroscience Letters · doi:10.1016/s0304-3940(99)00726-0 · Cited by 11
Mutations, developmental instability, and the Red Queen
Gangestad, S. W., & Yeo, R. A. (2006) · Behavioral and Brain Sciences · doi:10.1017/s0140525x06309090 · Cited by 9
The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes
Ritsner, M. S. (2009) · Springer eBooks · doi:10.1007/978-90-481-2298-1 · Cited by 9
Neurofunctional assessment of schizophrenia: A preliminary investigation of the presence of eye-tracking (SPEMS) and quality extinction test (QET) abno
Scarone, S., Gambini, O., Häfele, E., Bellodi, L., & Smeraldi, E. (1987) · Biological Psychology · doi:10.1016/0301-0511(87)90006-8 · Cited by 6
Finland's Galapagos: Founder effect, drift, and isolation in the inheritance of susceptibility alleles
Campbell, T. A., Osipova, D. V., & Kähkönen, S. (2006) · Behavioral and Brain Sciences · doi:10.1017/s0140525x06279093 · Cited by 4

Flagged first, then by citations

2 of the 274 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

Altman, 1990, Neuropsychological test deficits are associated with smooth pursuit eye movement impairment in affective disorders but not in schizophrenia, International Journal of Clinical Neuropsychology, 12, 49
Lawrie, 1999, Magnetic resonance imaging of brain in people at high risk of developing schizophrenia [comment], Lancet, 353, 30, 10.1016/S0140-6736(98)06244-8 · DOI

Sorted by citations

Schizophrenia
van Os, J., & Kapur, S. (2009) · The Lancet · doi:10.1016/s0140-6736(09)60995-8 · Cited by 1,971
Schizophrenia, “just the facts” 4. Clinical features and conceptualization
Tandon, R., Nasrallah, H. A., & Keshavan, M. S. (2009) · Schizophrenia Research · doi:10.1016/j.schres.2009.03.005 · Cited by 1,101
Why has it taken so long for biological psychiatry to develop clinical tests and what to do about it?
Kapur, S., Phillips, A. G., & Insel, T. R. (2012) · Molecular Psychiatry · doi:10.1038/mp.2012.105 · Cited by 980
Systematic meta-review and quality assessment of the structural brain alterations in schizophrenia
Shepherd, A. M., Laurens, K. R., Matheson, S. L., Carr, V. J., & Green, M. J. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.12.015 · Cited by 412
Differences in Resting-State Functional Magnetic Resonance Imaging Functional Network Connectivity Between Schizophrenia and Psychotic Bipolar Probands and Their Unaffected First-Degree Relatives
Meda, S. A., Gill, A., Stevens, M. C. G., Lorenzoni, R. P., Glahn, D. C., Calhoun, V. D., Sweeney, J. A., Tamminga, C. A., Keshavan, M. S., Thaker, G. K., et al. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.01.025 · Cited by 273
Self-citation

See all 210

Authors: Allen, A. J., Griss, M. E., Folley, B. S., Hawkins, K. A., & Pearlson, G. D.
Affiliations: Hartford Hospital (US)
Yale University (US)
Corresponding author: Allen, Allyssa J.
ORCID: Hawkins, Keith A.
Pearlson, Godfrey D.
Venue: Schizophrenia Research
Publisher: Elsevier BV
Published: 2009-04
Volume: 109
Issue: 1-3
Pages: 24-37
ISSN: 0920-9964 (ISSN-L)
DOI: 10.1016/j.schres.2009.01.016
PMC: PMC2665704
OpenAlex: W2102684787
Cited by: 210
References: 274
Citations by year: 2026: 5 · 2024: 3 · 2023: 6 · 2022: 2 · 2021: 9 · 2020: 11 · 2019: 10 · 2018: 6 · 2017: 16 · 2016: 15 · 2015: 21 · 2014: 20 · 2013: 21 · 2012: 29
FWCI: 2.53
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Schizophrenia Research (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Korea Electrotechnology Research Institute
National Institute of Mental Health (MH074797, R01MH074797, R37MH043775, R01MH077945)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurotransmitter Receptor Influence on Behavior
Keywords: schizophrenia, endophenotypes
MeSH terms: Cognition Disorders, Family, Humans, Phenotype, Schizophrenia, Schizophrenic Psychology, Statistics as Topic, Biomarkers, Cluster Analysis

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Endophenotypes in schizophrenia: A selective review

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